Fareston

Metastatic Breast Cancer
Treatment
1 Active Study for Fareston

What is Fareston

ToremifeneThe Generic name of this drug
Treatment SummaryRaloxifene is a drug used to treat post-menopausal women by imitating the effects of estrogen in the body. It affects the bones, cholesterol levels, and other areas that usually respond to estrogen. Unlike other hormones, it does not increase the risk of breast and uterine cancer.
Farestonis the brand name
image of different drug pills on a surface
Fareston Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Fareston
Toremifene
1997
5

Effectiveness

How Fareston Affects PatientsToremifene is a drug used to treat advanced breast cancer. It works by blocking the effects of estrogen, the hormone that can cause tumor growth, in the body. In animal tests, it has been shown to prevent the growth of tumors, and even cause them to shrink. It binds to the same receptors in the body as estrogen does, blocking estrogen from binding and therefore reducing its effects. Studies have also shown that it competes with estradiol (a form of estrogen) for binding sites in target tissues such as the breast.
How Fareston works in the bodyToremifene is a drug that works by binding to estrogen receptors. It can act like estrogen, block estrogen, or both, depending on how it's used. It's mainly used to fight breast cancer by blocking the growth-stimulating effects of estrogen in the tumor. It may also work by inducing cell death and changing the expression of certain genes and growth factors.

When to interrupt dosage

The prescribed measure of Fareston is contingent upon the diagnosed condition. The magnitude of dosage fluctuates, depending on the mode of delivery (e.g. Tablet - Oral or Tablet) specified in the table beneath.
Condition
Dosage
Administration
Metastatic Breast Cancer
, 60.0 mg
, Oral, Tablet, Tablet - Oral

Warnings

Fareston Contraindications
Condition
Risk Level
Notes
Hyperkalemia
Do Not Combine
Long QT Syndrome
Do Not Combine
uncorrected hypomagnesmia
Do Not Combine
There are 20 known major drug interactions with Fareston.
Common Fareston Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The serum concentration of Abemaciclib can be increased when it is combined with Toremifene.
Arsenic trioxide
Major
The risk or severity of QTc prolongation can be increased when Toremifene is combined with Arsenic trioxide.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Toremifene is combined with Artemether.
Asenapine
Major
The risk or severity of QTc prolongation can be increased when Toremifene is combined with Asenapine.
Astemizole
Major
The risk or severity of QTc prolongation can be increased when Toremifene is combined with Astemizole.
image of a doctor in a lab doing drug, clinical research

Fareston Novel Uses: Which Conditions Have a Clinical Trial Featuring Fareston?

There are 73 active investigations assessing the potential of Fareston to provide therapeutic relief for Metastatic Breast Cancer.
Condition
Clinical Trials
Trial Phases
Metastatic Breast Cancer
1 Actively Recruiting
Phase 1, Phase 2

Fareston Reviews: What are patients saying about Fareston?

5Patient Review
7/27/2010
Fareston for Breast Cancer that has Spread to Another Part of the Body
I had a tumor on my chest from breast cancer and went through several rounds of research drugs, all with terrible side effects. My doctor decided to do radiation, but before beginning, he prescribed this pill. I took it for three weeks and saw a significant reduction in the size of my tumor. After completing the course of radiation, I'm still taking the pill and the tumor is gone. Wonderful results!
3Patient Review
5/24/2012
Fareston for Breast Cancer that has Spread to Another Part of the Body
I was diagnosed with cancer in 2006 and underwent a mastectomy, chemo, and radiation. I started taking Fareston in 2007 after two other medications had side effects that caused me joint pain. The Fareston was marginally better by taking 1/2 pill in the morning and 1/2 before bed. April 2012 I was declared cancer-free after 5 years on Fareston. Within 2 weeks my knee pain was better. Vaginal discharge is worse (at age 66!!) Hoping that will improve in coming weeks.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about fareston

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who makes Fareston?

"Kyowa Kirin is an international company that creates Fareston. Fareston is a medication used to treat breast cancer."

Answered by AI

Is Fareston a chemo?

"Instead, it takes action on the estrogen receptors on the breast cancer cell’s surface, thereby slowing the progression of the cancer.

Fareston is a drug that is used to treat metastatic breast cancer. It works by blocking estrogen from reaching cancer cells, which slows the growth of the cancer."

Answered by AI

What is Fareston used for?

"Fareston is a drug used to treat breast cancer in postmenopausal women. It is a type of SERM, which is a drug that modulates the estrogen receptor."

Answered by AI

What is the difference between tamoxifen and toremifene?

"The two compounds only differ by a single chlorine atom, and have similar pharmacologic profiles. The major difference is in the preclinical activity; while tamoxifen is hepatocarcinogenic in high doses given over a long period of time to rats, toremifene is not."

Answered by AI

Clinical Trials for Fareston

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