Erivedge

Treatment

2 FDA approvals

0 Active Studies for Erivedge

What is Erivedge

VismodegibThe Generic name of this drug

Treatment SummaryVismodegib is a medication used to treat basal cell carcinoma, a type of skin cancer, in adults. It works by blocking a pathway that helps cancer cells grow. The FDA approved Vismodegib in 2012.

Erivedgeis the brand name

Erivedge Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Erivedge

Vismodegib

2012

Approved as Treatment by the FDA

Vismodegib, also called Erivedge, is approved by the FDA for 2 uses such as Locally Advanced Basal Cell Carcinoma and metastatic Basal cell carcinoma .

Locally Advanced Basal Cell Carcinoma

metastatic Basal cell carcinoma

Effectiveness

How Erivedge Affects PatientsVismodegib works by blocking a protein called Smoothened homologue, which stops signals from a pathway in the body called Hedgehog from getting through.

How Erivedge works in the bodyVismodegib stops an overactive protein from causing the skin to produce too many basal cells. This protein is called Smoothened homologue (SMO) and is part of the Hedgehog signaling pathway. By blocking SMO, Vismodegib can prevent uncontrolled cell production.

Warnings

Erivedge Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

There are 20 known major drug interactions with Erivedge.

Common Erivedge Drug Interactions

Drug Name

Risk Level

Description

Ozanimod

Major

Vismodegib may decrease the excretion rate of Ozanimod which could result in a higher serum level.

Rimegepant

Major

The serum concentration of Rimegepant can be increased when it is combined with Vismodegib.

(S)-Warfarin

Minor

The metabolism of (S)-Warfarin can be decreased when combined with Vismodegib.

Abrocitinib

Minor

The metabolism of Abrocitinib can be decreased when combined with Vismodegib.

Asunaprevir

Minor

The metabolism of Asunaprevir can be decreased when combined with Vismodegib.

Erivedge Toxicity & Overdose RiskTaking this drug may increase the chance of fetal death and birth defects. Possible side effects include muscle spasms, hair loss, changes in taste, weight loss, tiredness, nausea, diarrhea, reduced appetite, constipation, joint pain, vomiting, and loss of taste.

image of a doctor in a lab doing drug, clinical research

Erivedge Reviews: What are patients saying about Erivedge?

5Patient Review

1/27/2018

Erivedge for Basal Cell Carcinoma of the Skin

I've been taking this medication since 01/02/18 and I've seen a dramatic decrease in the number of sores on my head. Not to mention, it's helped with the size of some of the remaining sores. Additionally, I haven't experienced any negative side effects. This has really helped me boost my self-esteem.

3.7Patient Review

8/15/2019

Erivedge for Basal Cell Carcinoma of the Skin

Worked great for the first three months, then effectiveness petered out.

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Patient Q&A Section about erivedge

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Erivedge a chemotherapy?

"A targeted therapy is a cancer treatment that targets specific molecules involved in the growth and spread of cancer cells Erivedge (generic name: Vismodegib) is a chemotherapy drug used to treat cancer. In some cases, health care professionals may refer to it by its trade name, Erivedge. It is a targeted therapy, meaning it targets specific molecules involved in the growth and spread of cancer cells."

Answered by AI

What is Erivedge used for?

"Erivedge is a prescription medication used to treat adults with a type of skin cancer, called basal cell carcinoma, that has spread to other parts of the body, come back after surgery, or that your healthcare provider decides cannot be treated with surgery or radiation."

Answered by AI

What are the side effects of Erivedge?

"Side effects such as muscle spasms, hair loss, taste changes/loss, weight loss, tiredness, nausea, diarrhea, loss of appetite, constipation, vomiting, or joint pain may occur. If any of these effects persist or worsen, please tell your doctor or pharmacist."

Answered by AI