Erivedge
Treatment
2 FDA approvals
0 Active Studies for Erivedge
What is Erivedge
Vismodegib
The Generic name of this drug
Treatment Summary
Vismodegib is a medication used to treat basal cell carcinoma, a type of skin cancer, in adults. It works by blocking a pathway that helps cancer cells grow. The FDA approved Vismodegib in 2012.
Erivedge
is the brand name
Erivedge Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Erivedge
Vismodegib
2012
1
Approved as Treatment by the FDA
Vismodegib, also called Erivedge, is approved by the FDA for 2 uses such as metastatic Basal cell carcinoma and Locally Advanced Basal Cell Carcinoma .
metastatic Basal cell carcinoma
Locally Advanced Basal Cell Carcinoma
Effectiveness
How Erivedge Affects Patients
Vismodegib works by blocking a protein called Smoothened homologue, which stops signals from a pathway in the body called Hedgehog from getting through.
How Erivedge works in the body
Vismodegib stops an overactive protein from causing the skin to produce too many basal cells. This protein is called Smoothened homologue (SMO) and is part of the Hedgehog signaling pathway. By blocking SMO, Vismodegib can prevent uncontrolled cell production.
Warnings
Erivedge Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Erivedge.
Common Erivedge Drug Interactions
Drug Name
Risk Level
Description
Ozanimod
Major
Vismodegib may decrease the excretion rate of Ozanimod which could result in a higher serum level.
Rimegepant
Major
The serum concentration of Rimegepant can be increased when it is combined with Vismodegib.
(S)-Warfarin
Minor
The metabolism of (S)-Warfarin can be decreased when combined with Vismodegib.
Abrocitinib
Minor
The metabolism of Abrocitinib can be decreased when combined with Vismodegib.
Asunaprevir
Minor
The metabolism of Asunaprevir can be decreased when combined with Vismodegib.
Erivedge Toxicity & Overdose Risk
Taking this drug may increase the chance of fetal death and birth defects. Possible side effects include muscle spasms, hair loss, changes in taste, weight loss, tiredness, nausea, diarrhea, reduced appetite, constipation, joint pain, vomiting, and loss of taste.
Erivedge Reviews: What are patients saying about Erivedge?
5
Patient Review
1/27/2018
Erivedge for Basal Cell Carcinoma of the Skin
3.7
Patient Review
8/15/2019
Erivedge for Basal Cell Carcinoma of the Skin
Patient Q&A Section about erivedge
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Is Erivedge a chemotherapy?
"A targeted therapy is a cancer treatment that targets specific molecules involved in the growth and spread of cancer cells Erivedge (generic name: Vismodegib) is a chemotherapy drug used to treat cancer. In some cases, health care professionals may refer to it by its trade name, Erivedge. It is a targeted therapy, meaning it targets specific molecules involved in the growth and spread of cancer cells."
Answered by AI
What is Erivedge used for?
"Erivedge is a prescription medication used to treat adults with a type of skin cancer, called basal cell carcinoma, that has spread to other parts of the body, come back after surgery, or that your healthcare provider decides cannot be treated with surgery or radiation."
Answered by AI
What are the side effects of Erivedge?
"Side effects such as muscle spasms, hair loss, taste changes/loss, weight loss, tiredness, nausea, diarrhea, loss of appetite, constipation, vomiting, or joint pain may occur. If any of these effects persist or worsen, please tell your doctor or pharmacist."
Answered by AI
How long do you take Erivedge?
"Patients taking Erivedge stayed on the medication for anywhere from 3 weeks to 19 months."
Answered by AI