Pseudoephedrine for Barotrauma

Phase-Based Progress Estimates
John Muir Health, Walnut Creek, CABarotraumaPseudoephedrine Pill - Drug
All Sexes
What conditions do you have?

Study Summary

This trial studies if pseudoephedrine helps protect ears during high-pressure oxygen therapy (HBOT). It hopes to prevent ear trauma.

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: 45-60 minutes

1 minute
Incidence of completed compression
45-60 minutes
Compare changes in self-reported ear pain during hyperbaric oxygen therapy

Trial Safety

Trial Design

2 Treatment Groups

1 of 2
1 of 2

Experimental Treatment

Non-Treatment Group

90 Total Participants · 2 Treatment Groups

Primary Treatment: Pseudoephedrine · Has Placebo Group · N/A

Experimental Group · 1 Intervention: Pseudoephedrine Pill · Intervention Types: Drug
PlaceboComparator Group · 1 Intervention: Placebo · Intervention Types: Drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 45-60 minutes

Who is running the clinical trial?

John Muir HealthLead Sponsor
2 Previous Clinical Trials
458 Total Patients Enrolled
Jacinta Showers, RNPrincipal InvestigatorJohn Muir Health

Eligibility Criteria

Age 18+ · All Participants · 5 Total Inclusion Criteria

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Frequently Asked Questions

Are applications being accepted for participation in this trial?

"According to, the trial is actively enrolling participants as of now. It was initially published on January 31st 2023 and has been amended most recently on March 8th 2023." - Anonymous Online Contributor

Unverified Answer

How many participants are currently receiving the intervention in this clinical trial?

"Affirmative. The information available on indicates that recruitment for this medical trial is still ongoing, with the initial posting having been made on January 31st 2023 and last updated March 8th of the same year. This project requires 90 volunteers across a single location." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.