Semiconductor Embedded Socks for Ankle Sprains

Overseen By Study Coordinator

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: University of Colorado, Denver

Disqualifiers: Neurological, Surgical history, Chronic pain, Auto-immune, Tobacco, others

Compensation: Varies

Number of Visits: Unknown

Duration: 12 weeks

100 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether special socks made with semiconductor fabric can aid healing in ankle sprains more effectively than regular compression socks. Researchers aim to determine if these socks improve symptoms and function during recovery. Participants will wear these socks and monitor their symptoms as they heal. The trial seeks individuals who have experienced an ankle sprain or minor fracture and have had pain for at least one day. As an unphased trial, this study offers participants the chance to contribute to innovative research that could enhance recovery for future patients.

Do I need to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that semiconductor embedded socks are safe for ankle sprain rehabilitation?

Research suggests that socks made from special materials might aid healing by improving blood flow and reducing inflammation and pain. However, there is insufficient clear information about their safety for people. The trial is in the "Not Applicable" phase, indicating that the treatment is still under study. This often means there is limited knowledge about how well people can tolerate wearing the socks. Prospective participants should be aware that, while the concept is promising, the safety details remain incomplete. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about semiconductor embedded socks for ankle sprains because they offer a high-tech twist on traditional compression therapy. Unlike standard options like rest, ice, compression, and elevation (RICE) or elastic bandages, these socks incorporate semiconductor materials that can potentially enhance healing through improved blood flow and targeted compression. This innovative approach could provide faster recovery times and more efficient pain relief, making it a promising alternative to current methods.

What evidence suggests that semiconductor embedded socks are effective for ankle sprains?

This trial will compare the effectiveness of Semiconductor Embedded Socks with Control Compression Socks for ankle sprains. Research has shown that socks with special materials, like those in the Semiconductor Embedded Socks, may enhance recovery from ankle sprains by boosting blood flow, potentially speeding up healing. They also aim to reduce swelling and pain, common after an ankle injury. Early results suggest these socks might improve healing more effectively than regular compression socks. The special materials in the socks interact with the body to possibly offer additional benefits during recovery. ^{1 2 3 4 6}

Who Is on the Research Team?

Nicholas Alfonso, MD

Principal Investigator

University of Colorado Department of Orthopedics

Are You a Good Fit for This Trial?

This trial is for individuals with non-operative ankle sprains or avulsion fractures. Participants should be undergoing rehabilitation and willing to wear the provided socks throughout their recovery, recording symptoms and functional measures.

Inclusion Criteria

I have experienced pain for at least one day.

I have an ankle injury, including a sprain or a small bone break.

I am between 18 and 69 years old.

Exclusion Criteria

Patients with neurological conditions

Patients with tobacco use in last 90 days

I have had surgery for a lower limb injury before.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants wear semiconductor embedded socks throughout a 12-week course of rehabilitation for non-surgically treated ankle sprain or fracture injury

12 weeks

Regular visits for monitoring and assessment

Follow-up

Participants are monitored for safety and effectiveness after treatment, with outcome measures collected at standard intervals up to 1 year

6 months

What Are the Treatments Tested in This Trial?

Interventions

• Semiconductor Embedded Sock

Trial Overview The study tests if semiconductor fabric in socks can improve healing compared to regular compression socks. It will assess how these special socks affect injury outcomes and function during treatment.

How Is the Trial Designed?

Group I: Semiconductor Embedded Sock Experimental Treatment 1 Intervention

Group II: Control Compression Sock Placebo Group 1 Intervention

Who Is Running the Clinical Trial?

University of Colorado, Denver

Lead Sponsor

Trials

1,842

Recruited

3,028,000+

INCREDIWEAR HOLDINGS, INC.

Industry Sponsor

Trials

6

Recruited

630+

University of Colorado Health

Collaborator

Trials

4

Recruited

1,000+

Citations

1. clinicaltrials.gov clinicaltrials.gov/study/NCT07025733

Semiconductor Embedded Socks for Ankle Sprains The goal of this clinical trial is to determine if semiconductor fabric embedded in socks can improve healing after non operative ankle sprains.

2. patlynk.com patlynk.com/trial/NCT07025733

Therapeutic Semiconductor Socks for Ankle Injury Recovery These socks are embedded with semiconductors that can help increase blood circulation, reduce inflammation and pain, and enhance the healing process. The goal ...

3. withpower.com withpower.com/trial/phase-fractures-avulsion-3-2025-ba191

Semiconductor Embedded Socks for Ankle Sprains The goal of this clinical trial is to determine if semiconductor fabric embedded in socks can improve healing after non operative ankle sprains.

4. trialstoday.org trialstoday.org/search/results?status=recruiting&gender=&age=&zip=&radius=25&condition=&healthy=&type=&interventionalpurpose=&observationalmodel=&query=University%20of%20Iowa%20Neurology&page=eJyLVspLrShR0lHycw4xMDE2MzI0N1PS0bWEARxMMz1jYyMDc3MdQ3NTQ2MjCwMw0FHKSy4xMDMwMzI2MVKKBQDVxhSF

Save Selected The main questions it aims to answer are: 1. How does semiconductor embedded sock effect outcomes in patients undergoing rehabilitation from ankle injury? 2.

5. go.drugbank.com go.drugbank.com/conditions/DBCOND0048995

Ankle Sprains (DBCOND0048995) Semiconductor Embedded Socks for Ankle Sprains, No drug interventions, treatment, Not Available, recruiting. NCT06962943. Auto-regulated Blood Flow Restriction ...

6. mdpi.com mdpi.com/2076-3417/15/3/1584

Concept Protocol for Developing a DAid® Smart Socks ... The data will be used to provide immediate feedback on movement patterns, allowing athletes to correct improper techniques that could lead to injuries. This ...