Diovan Hct

Hypesthesia, Hypesthesia, Hypesthesia + 15 more
Treatment
11 FDA approvals
20 Active Studies for Diovan Hct

What is Diovan Hct

ValsartanThe Generic name of this drug
Treatment SummaryValsartan is a medication that belongs to a class of drugs called angiotensin II receptor blockers (ARBs). These drugs are used to lower blood pressure, reduce aldosterone levels, and increase the excretion of sodium. They work by blocking the action of angiotensin II, a protein that causes blood vessels to constrict and increases fluid retention. Valsartan is often used to treat hypertension, heart failure, and Type 2 Diabetes-associated nephropathy. It is generally well-tolerated with fewer side effects than other antihypertensive medications. Valsartan was approved in
Diovanis the brand name
image of different drug pills on a surface
Diovan Hct Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Diovan
Valsartan
1996
621

Approved as Treatment by the FDA

Valsartan, also known as Diovan, is approved by the FDA for 11 uses such as Heart failure and High Blood Pressure .
Heart failure
Used to treat Heart Failure in combination with Sacubitril
High Blood Pressure
Used to treat Moderate Essential Hypertension in combination with Hydrochlorothiazide
chronic heart failure with reduced ejection fraction (NYHA Class II-IV)
Used to treat chronic heart failure with reduced ejection fraction (NYHA Class II-IV) in combination with Sacubitril
Heart Failure
Used to treat hospitalization due to cardiac failure in combination with Sacubitril
Systolic Left Ventricular Dysfunction
Used to treat Systolic Left Ventricular Dysfunction in combination with Sacubitril
Moderate Essential Hypertension
Used to treat Moderate Essential Hypertension in combination with Hydrochlorothiazide
Combined Modality Therapy
Used to treat patients for whom combination therapy is appropriate in combination with Hydrochlorothiazide
Cardiovascular Mortality
Used to treat Cardiovascular Mortality in combination with Sacubitril
Hypesthesia
Used to treat chronic heart failure with reduced ejection fraction (NYHA Class II-IV) in combination with Sacubitril
Congestive Heart Failure
Used to treat Heart Failure in combination with Sacubitril
Ventricular Dysfunction, Left
Used to treat Systolic Left Ventricular Dysfunction in combination with Sacubitril

Effectiveness

How Diovan Hct Affects PatientsValsartan works by blocking the effects of angiotensin II, a hormone that helps regulate blood pressure. When taking this drug, people may experience a drop in blood pressure, and could be more likely to have low blood pressure if they are dehydrated or taking diuretics. It is important to be careful when starting treatment in patients with heart failure, as the drug can cause further reduction in blood pressure. If this happens, the patient should be put in a lying down position and may need to receive a saline solution. In rare cases, taking valsartan can lead to an increase in potassium levels, especially in
How Diovan Hct works in the bodyValsartan is a medication used to lower blood pressure. It belongs to the angiotensin II receptor blocker family of drugs, which block angiotensin receptor 1 and prevent angiotensin II from binding. This helps reduce hypertension, lower aldosterone levels, reduce cardiac activity, and increase sodium excretion. Valsartan also works on the renin-angiotensin aldosterone system, which helps regulate kidney, vascular, and cardiac functions. It has been shown to improve cardiovascular outcomes and reduce risk of heart attack, stroke, and heart failure. It is commonly used to manage hypertension, heart

When to interrupt dosage

The proposed dosage of Diovan Hct is reliant upon the diagnosed condition, such as initial treatment, Left Ventricular Failure, Unspecified and Combined Modality Therapy. The amount of dosage is contingent upon the technique of administration (e.g. Tablet - Oral or Tablet, film coated) noted in the table below.
Condition
Dosage
Administration
Hypesthesia
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Hypesthesia
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Hypesthesia
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Hypesthesia
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Diabetic Nephropathies
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Congestive Heart Failure
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Type 2 Diabetes
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
High Blood Pressure
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Cardiovascular Mortality
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Hypertensive disease
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Combined Modality Therapy
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
initial treatment
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
multiple antihypertensive drugs likely required
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
not adequately controlled with monotherapy
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Ventricular Dysfunction, Left
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Left Ventricular Failure, Unspecified
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Ventricular Dysfunction, Left
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral
Heart Failure
160.0 mg, 320.0 mg, , 80.0 mg, 40.0 mg, 1.6 mg, 3.2 mg, 26.0 mg, 51.0 mg, 103.0 mg, 4.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral

Warnings

Diovan Hct Contraindications
Condition
Risk Level
Notes
Type 2 Diabetes
Do Not Combine
Breast Milk Production
Do Not Combine
Diabetes
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Valsartan may interact with Pulse Frequency
There are 20 known major drug interactions with Diovan Hct.
Common Diovan Hct Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Valsartan.
Amifostine
Major
Valsartan may increase the hypotensive activities of Amifostine.
Cabozantinib
Major
The metabolism of Cabozantinib can be decreased when combined with Valsartan.
Capecitabine
Major
The metabolism of Capecitabine can be decreased when combined with Valsartan.
Cyclophosphamide
Major
The metabolism of Cyclophosphamide can be decreased when combined with Valsartan.
Diovan Hct Toxicity & Overdose RiskValsartan has been found to be toxic to rats in doses higher than 2000mg/kg. When given to pregnant mice, rats and rabbits, there were no signs of birth defects, but there were signs of decreased fetal weight and pup survival rate. If pregnant women take valsartan, it can harm the fetus and should be stopped as soon as possible.
image of a doctor in a lab doing drug, clinical research

Diovan Hct Novel Uses: Which Conditions Have a Clinical Trial Featuring Diovan Hct?

Currently, 510 active clinical trials are underway to assess the potential of Diovan Hct to ameliorate Type 2 Diabetes, Diabetic Nephropathy and Hypertension.
Condition
Clinical Trials
Trial Phases
Hypesthesia
7 Actively Recruiting
Not Applicable, Early Phase 1, Phase 1
Diabetic Nephropathies
0 Actively Recruiting
Ventricular Dysfunction, Left
1 Actively Recruiting
Phase 2, Phase 3
Type 2 Diabetes
175 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1
High Blood Pressure
4 Actively Recruiting
Not Applicable, Early Phase 1
Congestive Heart Failure
175 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Phase 3, Early Phase 1
Hypesthesia
2 Actively Recruiting
Not Applicable
Cardiovascular Mortality
0 Actively Recruiting
Hypertensive disease
23 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Ventricular Dysfunction, Left
0 Actively Recruiting
Combined Modality Therapy
0 Actively Recruiting
Heart Failure
0 Actively Recruiting
Left Ventricular Failure, Unspecified
0 Actively Recruiting
Hypesthesia
0 Actively Recruiting
not adequately controlled with monotherapy
0 Actively Recruiting
Hypesthesia
10 Actively Recruiting
Not Applicable, Phase 1
initial treatment
0 Actively Recruiting
multiple antihypertensive drugs likely required
0 Actively Recruiting

Diovan Hct Reviews: What are patients saying about Diovan Hct?

5Patient Review
7/13/2014
Diovan Hct for High Blood Pressure
This medication has been key in keeping my blood pressure at a normal level.
5Patient Review
2/6/2016
Diovan Hct for High Blood Pressure
This treatment was very effective in lowering my blood pressure. I only need to take half a tablet now, and my BP has been normal for over 10 years.
5Patient Review
10/4/2013
Diovan Hct for High Blood Pressure
4.7Patient Review
9/18/2015
Diovan Hct for High Blood Pressure
I take Valsartan HCT 160/25 for high blood pressure. I'm mostly concerned with the frequency of urination it causes---sometimes I have to get up five times a night. My blood pressure usually stays in the range of 135-160 on the upper end and 67-80 on the lower end during the day.
4.7Patient Review
6/30/2016
Diovan Hct for High Blood Pressure
I was using co-diovan before, but now I'm on diovan 80 mg. It seems to be working well for me; there's just a bit of dizziness, but my blood pressure is controlled much better.
View All Reviews
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Patient Q&A Section about diovan hct

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the side effects of valsartan hydrochlorothiazide?

"The most common side effects of valsartan/hydrochlorothiazide are headache, dizziness, and nose and throat infections."

Answered by AI

What is Diovan HCT used for?

"Valsartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). Hydrochlorothiazide belongs to a class of drugs called thiazide diuretics (water pills).

This drug is used to treat high blood pressure by lowering it. This prevents strokes, heart attacks, and kidney problems. The drug is a combination of two medications, valsartan and hydrochlorothiazide. Valsartan is an angiotensin receptor blocker (ARB), while hydrochlorothiazide is a thiazide diuretic (water pill)."

Answered by AI

What is the generic name of Diovan HCT?

"Diovan HCT is a combination medication that contains an angiotensin receptor blocker and a diuretic. It is used to treat hypertension, or high blood pressure."

Answered by AI

What is the difference between Diovan and Diovan HCT?

"Diovan is for hypertension in adults and children one year and older. Diovan HCT is a combination of valsartan (Diovan) and hydrochlorothiazide (HCTZ)."

Answered by AI

Clinical Trials for Diovan Hct

Have you considered Diovan Hct clinical trials? We made a collection of clinical trials featuring Diovan Hct, we think they might fit your search criteria.
Have you considered Diovan Hct clinical trials? We made a collection of clinical trials featuring Diovan Hct, we think they might fit your search criteria.
Have you considered Diovan Hct clinical trials? We made a collection of clinical trials featuring Diovan Hct, we think they might fit your search criteria.