Clenpiq

Indigestion, Heartburn, Nutritional supplementation + 1 more

Treatment

5 FDA approvals

8 Active Studies for Clenpiq

What is Clenpiq

Magnesium oxide

The Generic name of this drug

Treatment Summary

Magnesium oxide is a type of mineral found in nature. It is used to neutralize stomach acid and as a mild laxative. It can also be used in a variety of other applications outside of medicine.

PNV-Select

is the brand name

image of different drug pills on a surface

Clenpiq Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

PNV-Select

Magnesium oxide

1990

8

Approved as Treatment by the FDA

Magnesium oxide, also called PNV-Select, is approved by the FDA for 5 uses like Heartburn and Nutritional supplementation .

Heartburn

Nutritional supplementation

Bowel preparation therapy

Used to treat Bowel preparation therapy in combination with Citric acid

Indigestion

Heartburn

Effectiveness

How Clenpiq works in the body

Milk of Magnesia is a white liquid made of magnesium hydroxide. It is used to treat constipation, indigestion, and heartburn. This liquid helps the body get rid of waste by drawing fluid into the intestine and increasing the amount of water in the bowel. This makes it easier to pass stools. Magnesium also helps to reduce platelet aggregation by blocking calcium from entering the body.

When to interrupt dosage

The suggested measure of Clenpiq is contingent upon the recognized condition, including Bowel preparation therapy, Acid indigestion and Nutritional supplementation. The amount of dosage is differentiated by the method of delivery (e.g. Capsule - Oral or Oral) featured in the table beneath.

Condition

Dosage

Administration

Bowel preparation therapy

400.0 mg, , 253.0 mg, 75.0 mg, 25.0 mg, 45.0 mg, 30.0 mg, 3500.0 mg, 250.0 mg, 241.8 mg, 50.0 mg, 82.0 mg, 410.0 mg, 420.0 mg, 100.0 mg, 136.0 mg, 167.0 mg, 133.0 mg, 82.9 mg, 96.9 mg, 96.95 mg, 63.0 mg, 0.35 mg/mg, 60.0 mg, 0.5 mg/mg, 170.0 mg, 10.0 mg, 66.6 mg, 155.0 mg, 663.0 mg, 600.0 mg, 84.0 mg, 140.0 mg, 125.0 mg, 500.0 mg, 200.0 mg, 35.0 mg/mL, 15.0 mg, 20.0 mg, 0.03 mg, 12.0 mg/mL, 40.0 mg, 10.0 mg/mL, 1.0 mg/mg, 158.0 mg, 0.005 mg, 35.0 mg, 90.0 mg, 60.3 mg, 5.0 mg, 37.5 mg, 3.8 mg/mL, 1.9 mg/mL, 0.04 mg/mg, 62.5 mg, 115.0 mg, 0.03846 mg/mg, 0.00421 mg/mg, 0.0532 mg/mg, 300.0 mg, 166.67 mg, 150.0 mg, 70.0 mg, 166.0 mg, 0.01 mg/mg, 240.0 mg/mL, 165.0 mg, 166.6 mg, 30.0 mg/mL, 252.0 mg, 133.3 mg, 87.5 mg, 62.0 mg, 66.67 mg, 20.0 mg/mL, 72.75 mg, 142.5 mg

, Tablet, Oral, Tablet - Oral, Tablet, coated - Oral, Tablet, coated, Kit, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Powder, for solution, Powder, for solution - Oral, Capsule - Oral, Capsule, Powder, metered - Oral, Powder, metered, Irrigation, Solution - Irrigation, Solution, Liquid - Irrigation, Liquid, Tablet, chewable, Tablet, extended release - Oral, Tablet, extended release, Tablet, chewable - Oral, Liquid - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit - Oral, Wafer - Oral, Wafer, Capsule, liquid filled, Capsule, liquid filled - Oral, Pill, Pill - Oral, Powder, Powder - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Oral; Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Indigestion

400.0 mg, , 253.0 mg, 75.0 mg, 25.0 mg, 45.0 mg, 30.0 mg, 3500.0 mg, 250.0 mg, 241.8 mg, 50.0 mg, 82.0 mg, 410.0 mg, 420.0 mg, 100.0 mg, 136.0 mg, 167.0 mg, 133.0 mg, 82.9 mg, 96.9 mg, 96.95 mg, 63.0 mg, 0.35 mg/mg, 60.0 mg, 0.5 mg/mg, 170.0 mg, 10.0 mg, 66.6 mg, 155.0 mg, 663.0 mg, 600.0 mg, 84.0 mg, 140.0 mg, 125.0 mg, 500.0 mg, 200.0 mg, 35.0 mg/mL, 15.0 mg, 20.0 mg, 0.03 mg, 12.0 mg/mL, 40.0 mg, 10.0 mg/mL, 1.0 mg/mg, 158.0 mg, 0.005 mg, 35.0 mg, 90.0 mg, 60.3 mg, 5.0 mg, 37.5 mg, 3.8 mg/mL, 1.9 mg/mL, 0.04 mg/mg, 62.5 mg, 115.0 mg, 0.03846 mg/mg, 0.00421 mg/mg, 0.0532 mg/mg, 300.0 mg, 166.67 mg, 150.0 mg, 70.0 mg, 166.0 mg, 0.01 mg/mg, 240.0 mg/mL, 165.0 mg, 166.6 mg, 30.0 mg/mL, 252.0 mg, 133.3 mg, 87.5 mg, 62.0 mg, 66.67 mg, 20.0 mg/mL, 72.75 mg, 142.5 mg

, Tablet, Oral, Tablet - Oral, Tablet, coated - Oral, Tablet, coated, Kit, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Powder, for solution, Powder, for solution - Oral, Capsule - Oral, Capsule, Powder, metered - Oral, Powder, metered, Irrigation, Solution - Irrigation, Solution, Liquid - Irrigation, Liquid, Tablet, chewable, Tablet, extended release - Oral, Tablet, extended release, Tablet, chewable - Oral, Liquid - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit - Oral, Wafer - Oral, Wafer, Capsule, liquid filled, Capsule, liquid filled - Oral, Pill, Pill - Oral, Powder, Powder - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Oral; Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Nutritional supplementation

400.0 mg, , 253.0 mg, 75.0 mg, 25.0 mg, 45.0 mg, 30.0 mg, 3500.0 mg, 250.0 mg, 241.8 mg, 50.0 mg, 82.0 mg, 410.0 mg, 420.0 mg, 100.0 mg, 136.0 mg, 167.0 mg, 133.0 mg, 82.9 mg, 96.9 mg, 96.95 mg, 63.0 mg, 0.35 mg/mg, 60.0 mg, 0.5 mg/mg, 170.0 mg, 10.0 mg, 66.6 mg, 155.0 mg, 663.0 mg, 600.0 mg, 84.0 mg, 140.0 mg, 125.0 mg, 500.0 mg, 200.0 mg, 35.0 mg/mL, 15.0 mg, 20.0 mg, 0.03 mg, 12.0 mg/mL, 40.0 mg, 10.0 mg/mL, 1.0 mg/mg, 158.0 mg, 0.005 mg, 35.0 mg, 90.0 mg, 60.3 mg, 5.0 mg, 37.5 mg, 3.8 mg/mL, 1.9 mg/mL, 0.04 mg/mg, 62.5 mg, 115.0 mg, 0.03846 mg/mg, 0.00421 mg/mg, 0.0532 mg/mg, 300.0 mg, 166.67 mg, 150.0 mg, 70.0 mg, 166.0 mg, 0.01 mg/mg, 240.0 mg/mL, 165.0 mg, 166.6 mg, 30.0 mg/mL, 252.0 mg, 133.3 mg, 87.5 mg, 62.0 mg, 66.67 mg, 20.0 mg/mL, 72.75 mg, 142.5 mg

, Tablet, Oral, Tablet - Oral, Tablet, coated - Oral, Tablet, coated, Kit, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Powder, for solution, Powder, for solution - Oral, Capsule - Oral, Capsule, Powder, metered - Oral, Powder, metered, Irrigation, Solution - Irrigation, Solution, Liquid - Irrigation, Liquid, Tablet, chewable, Tablet, extended release - Oral, Tablet, extended release, Tablet, chewable - Oral, Liquid - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit - Oral, Wafer - Oral, Wafer, Capsule, liquid filled, Capsule, liquid filled - Oral, Pill, Pill - Oral, Powder, Powder - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Oral; Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Heartburn

400.0 mg, , 253.0 mg, 75.0 mg, 25.0 mg, 45.0 mg, 30.0 mg, 3500.0 mg, 250.0 mg, 241.8 mg, 50.0 mg, 82.0 mg, 410.0 mg, 420.0 mg, 100.0 mg, 136.0 mg, 167.0 mg, 133.0 mg, 82.9 mg, 96.9 mg, 96.95 mg, 63.0 mg, 0.35 mg/mg, 60.0 mg, 0.5 mg/mg, 170.0 mg, 10.0 mg, 66.6 mg, 155.0 mg, 663.0 mg, 600.0 mg, 84.0 mg, 140.0 mg, 125.0 mg, 500.0 mg, 200.0 mg, 35.0 mg/mL, 15.0 mg, 20.0 mg, 0.03 mg, 12.0 mg/mL, 40.0 mg, 10.0 mg/mL, 1.0 mg/mg, 158.0 mg, 0.005 mg, 35.0 mg, 90.0 mg, 60.3 mg, 5.0 mg, 37.5 mg, 3.8 mg/mL, 1.9 mg/mL, 0.04 mg/mg, 62.5 mg, 115.0 mg, 0.03846 mg/mg, 0.00421 mg/mg, 0.0532 mg/mg, 300.0 mg, 166.67 mg, 150.0 mg, 70.0 mg, 166.0 mg, 0.01 mg/mg, 240.0 mg/mL, 165.0 mg, 166.6 mg, 30.0 mg/mL, 252.0 mg, 133.3 mg, 87.5 mg, 62.0 mg, 66.67 mg, 20.0 mg/mL, 72.75 mg, 142.5 mg

, Tablet, Oral, Tablet - Oral, Tablet, coated - Oral, Tablet, coated, Kit, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Powder, for solution, Powder, for solution - Oral, Capsule - Oral, Capsule, Powder, metered - Oral, Powder, metered, Irrigation, Solution - Irrigation, Solution, Liquid - Irrigation, Liquid, Tablet, chewable, Tablet, extended release - Oral, Tablet, extended release, Tablet, chewable - Oral, Liquid - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit - Oral, Wafer - Oral, Wafer, Capsule, liquid filled, Capsule, liquid filled - Oral, Pill, Pill - Oral, Powder, Powder - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Oral; Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Warnings

There are 20 known major drug interactions with Clenpiq.

Common Clenpiq Drug Interactions

Drug Name

Risk Level

Description

2,5-Dimethoxy-4-ethylamphetamine

Major

The serum concentration of 2,5-Dimethoxy-4-ethylamphetamine can be increased when it is combined with Magnesium oxide.

2,5-Dimethoxy-4-ethylthioamphetamine

Major

The serum concentration of 2,5-Dimethoxy-4-ethylthioamphetamine can be increased when it is combined with Magnesium oxide.

4-Bromo-2,5-dimethoxyamphetamine

Major

The serum concentration of 4-Bromo-2,5-dimethoxyamphetamine can be increased when it is combined with Magnesium oxide.

Amphetamine/Dextroamphetamine

Major

The serum concentration of Amphetamine can be increased when it is combined with Magnesium oxide.

Atazanavir

Major

Magnesium oxide can cause a decrease in the absorption of Atazanavir resulting in a reduced serum concentration and potentially a decrease in efficacy.

image of a doctor in a lab doing drug, clinical research

Clenpiq Novel Uses: Which Conditions Have a Clinical Trial Featuring Clenpiq?

6 active clinical trials are assessing the potential of Clenpiq to reduce Heartburn, facilitate Bowel preparation therapy and promote Nutritional supplementation.

Condition

Clinical Trials

Trial Phases

Indigestion

6 Actively Recruiting

Phase 3, Not Applicable, Phase 2

Heartburn

2 Actively Recruiting

Phase 3, Not Applicable

Bowel preparation therapy

1 Actively Recruiting

Phase 1, Phase 2

Nutritional supplementation

0 Actively Recruiting

Clenpiq Reviews: What are patients saying about Clenpiq?

5

Patient Review

6/9/2022

Clenpiq for Emptying of the Bowel

I'm an experienced user, and I have to say that Clenpiq was great! Easy to use and no cramping. Would recommend it to anyone.

5

Patient Review

7/15/2022

Clenpiq for Emptying of the Bowel

The prep for this was easy to take and follow. I wasn't hungry or feeling any negative effects like a headache from dehydration, which was great.

3.3

Patient Review

6/22/2022

Clenpiq for Emptying of the Bowel

This did a great job at cleansing my bowels for colonoscopy, but I didn't love the taste. It's very salty and bitter, not sweet like some people said. I had to drink it quickly and chase each gulp with apple juice, which made me a little nauseous.

3

Patient Review

10/18/2022

Clenpiq for Emptying of the Bowel

The containers were very difficult to open. The taste and texture were also pretty bad, but I'm glad the nurse warned me to sip it slowly and alternate with tea or broth. I didn't get a full clean-out, but the doctor said it was okay.

2

Patient Review

10/28/2022

Clenpiq for Emptying of the Bowel

I don't think I can ever drink this again. It was the most awful tasting drink. I was gagging even though I chased it with sweet tea. Ended up throwing up about 5 times.

2

Patient Review

10/23/2022

Clenpiq for Emptying of the Bowel

The only good things about this product are the bottle shape and flavoring. It took hours before I saw any results, and then it dragged on for even longer. My insurance made me use this as it would not cover Suprep any longer, but next time I will pay out of pocket. Suprep works in 30 minutes and is done within 2 hours. With Clenpiq I wasn't even fully clear after the entire prep.

1.7

Patient Review

7/31/2022

Clenpiq for Emptying of the Bowel

Clenpiq was awful! It tastes like concentrated cough syrup. I could taste it in my throat, tongue, and teeth—I almost threw up. But I knew I needed it, so I choked it down. And then I realized I had a whole new bottle to drink! There's got to be an easier way. No wonder people put their colonoscopies off!

1.7

Patient Review

10/31/2022

Clenpiq for Emptying of the Bowel

The prep for this was really tough to go through. I found that Miralax mixed with juice was a better method and worked much faster. The bottle says cranberry flavor but it tasted nothing like it.

1.7

Patient Review

8/4/2022

Clenpiq for Emptying of the Bowel

Clenpiq was a total nightmare for me. I lost all control after taking it and it's still affecting me months later. Avoid if you can.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about clenpiq

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How long do you poop with Clenpiq?

"— Some people will have multiple urgent bowel movements within 30 minutes of drinking the solution and others may not have a bowel movement for 3-4 hours."

Answered by AI

How fast should you drink Clenpiq?

"Drink one bottle of CLENPIQ, then drink one cup (8-ounces each) of clear liquid every 15 minutes for at least four cups. You may continue drinking clear liquids up to 3 hours before your exam."

Answered by AI

Is Clenpiq a good bowel prep?

"Of the 231 people who rated Clenpiq, the average rating was 5.9 out of 10."

Answered by AI

Does Clenpiq make you throw up?

"If you start to feel nauseous or vomit, drink the solution more slowly. Try to drink all of it even if it takes longer. If vomiting continues, or you can't finish the preparation, stop taking it and call your doctor's office for further instructions."

Answered by AI

Clinical Trials for Clenpiq

Image of Mayo Clinic in Rochester in Rochester, United States.

High Resolution Gastric Mapping and Gastroduodenal Manometry for Indigestion

18 - 80
All Sexes
Rochester, MN

Dyspepsia is a common problem attributed to gastric sensorimotor dysfunctions ie, delayed, or less frequently rapid gastric emptying (GE), impaired gastric accommodation, and increased gastric sensation. Therapeutic options manage symptoms, and there is no FDA approved medical therapy for dyspepsia. There is a need for better objective understanding of sensorimotor dysfunction in dyspepsia, as well as noninvasive, efficacious, safe, and inexpensive treatments for dyspepsia. The purpose of this research is to identify disturbances and characterize phenotypes in patients with functional dyspepsia, and to assess the correlations between symptoms (during the manometry and in daily life), gastric emptying, electrical activity (BSGM), and pressure activity (manometry).

Recruiting
Has No Placebo

Mayo Clinic in Rochester

Nicholas R Oblizajek, MD

Image of G. Oppenheimer Center for Neurobiology of Stress and Resilience in Los Angeles, United States.

Biofeedback for Functional Abdominal Bloating

18 - 80
All Sexes
Los Angeles, CA

Background. Abdominal distention is produced by an abnormal somatic postural tone. The authors developed an original biofeedback technique. In a randomized, placebo-controlled trial the authors demonstrated the superiority of biofeedback over placebo for the treatment of abdominal distention. However, the technique is technically complex and unpractical. Aim. To prove the efficacy of a noninstrumental biofeedback technique, transmitted by a standard training program, for the treatment of abdominal distension in different centers. Selection criteria. Episodes of visible abdominal distension. Intervention. Patients will be randomized into biofeedback and placebo groups. Three sessions of either biofeedback or placebo intervention will be performed during the first 3 weeks of the intervention period. Biofeedback: Patients will be taught to control abdominal and thoracic muscular activity by providing instructions using an original video support. In each center one operator will receive a standard training on how to deliver the noninstrumental biofeedback treatment. Patients will be instructed to perform the same exercises before and after breakfast, lunch and dinner during the 4-week intervention period. Placebo: Sham measurements of abdominal and thoracic motion will be performed, and a pill of placebo containing 0.21 g glucose will be administered; patients will be instructed to take a pill of placebo before breakfast, lunch and dinner during the 4-week intervention period.

Recruiting
Paid Trial

G. Oppenheimer Center for Neurobiology of Stress and Resilience (+1 Sites)

Fernando Azpiroz, MD

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