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What is Clenpiq
Magnesium oxideThe Generic name of this drug
Treatment SummaryMagnesium oxide is a type of mineral found in nature. It is used to neutralize stomach acid and as a mild laxative. It can also be used in a variety of other applications outside of medicine.
PNV-Selectis the brand name
Clenpiq Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
PNV-Select
Magnesium oxide
1990
8
Approved as Treatment by the FDA
Magnesium oxide, also called PNV-Select, is approved by the FDA for 4 uses like Nutritional supplementation and Bowel preparation therapy .Nutritional supplementation
Bowel preparation therapy
Used to treat Bowel preparation therapy in combination with Citric acid
Indigestion
Heartburn
Effectiveness
How Clenpiq works in the bodyMilk of Magnesia is a white liquid made of magnesium hydroxide. It is used to treat constipation, indigestion, and heartburn. This liquid helps the body get rid of waste by drawing fluid into the intestine and increasing the amount of water in the bowel. This makes it easier to pass stools. Magnesium also helps to reduce platelet aggregation by blocking calcium from entering the body.
When to interrupt dosage
The suggested measure of Clenpiq is contingent upon the recognized condition, including Bowel preparation therapy, Acid indigestion and Nutritional supplementation. The amount of dosage is differentiated by the method of delivery (e.g. Capsule - Oral or Oral) featured in the table beneath.Condition
Dosage
Administration
Indigestion
400.0 mg, , 253.0 mg, 75.0 mg, 25.0 mg, 45.0 mg, 30.0 mg, 3500.0 mg, 250.0 mg, 241.8 mg, 50.0 mg, 82.0 mg, 410.0 mg, 420.0 mg, 100.0 mg, 136.0 mg, 167.0 mg, 133.0 mg, 82.9 mg, 96.9 mg, 96.95 mg, 63.0 mg, 0.35 mg/mg, 60.0 mg, 0.5 mg/mg, 170.0 mg, 10.0 mg, 66.6 mg, 155.0 mg, 663.0 mg, 600.0 mg, 84.0 mg, 140.0 mg, 125.0 mg, 500.0 mg, 200.0 mg, 35.0 mg/mL, 15.0 mg, 20.0 mg, 0.03 mg, 12.0 mg/mL, 40.0 mg, 10.0 mg/mL, 1.0 mg/mg, 158.0 mg, 0.005 mg, 35.0 mg, 90.0 mg, 60.3 mg, 5.0 mg, 37.5 mg, 3.8 mg/mL, 1.9 mg/mL, 0.04 mg/mg, 62.5 mg, 115.0 mg, 0.03846 mg/mg, 0.00421 mg/mg, 0.0532 mg/mg, 300.0 mg, 166.67 mg, 150.0 mg, 70.0 mg, 166.0 mg, 0.01 mg/mg, 240.0 mg/mL, 165.0 mg, 166.6 mg, 30.0 mg/mL, 252.0 mg, 133.3 mg, 87.5 mg, 62.0 mg, 66.67 mg, 20.0 mg/mL, 72.75 mg, 142.5 mg
, Tablet, Oral, Tablet - Oral, Tablet, coated - Oral, Tablet, coated, Kit, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Powder, for solution, Powder, for solution - Oral, Capsule - Oral, Capsule, Powder, metered - Oral, Powder, metered, Irrigation, Solution - Irrigation, Solution, Liquid - Irrigation, Liquid, Tablet, chewable, Tablet, extended release - Oral, Tablet, extended release, Tablet, chewable - Oral, Liquid - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit - Oral, Wafer - Oral, Wafer, Capsule, liquid filled, Capsule, liquid filled - Oral, Pill, Pill - Oral, Powder, Powder - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Oral; Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Nutritional supplementation
400.0 mg, , 253.0 mg, 75.0 mg, 25.0 mg, 45.0 mg, 30.0 mg, 3500.0 mg, 250.0 mg, 241.8 mg, 50.0 mg, 82.0 mg, 410.0 mg, 420.0 mg, 100.0 mg, 136.0 mg, 167.0 mg, 133.0 mg, 82.9 mg, 96.9 mg, 96.95 mg, 63.0 mg, 0.35 mg/mg, 60.0 mg, 0.5 mg/mg, 170.0 mg, 10.0 mg, 66.6 mg, 155.0 mg, 663.0 mg, 600.0 mg, 84.0 mg, 140.0 mg, 125.0 mg, 500.0 mg, 200.0 mg, 35.0 mg/mL, 15.0 mg, 20.0 mg, 0.03 mg, 12.0 mg/mL, 40.0 mg, 10.0 mg/mL, 1.0 mg/mg, 158.0 mg, 0.005 mg, 35.0 mg, 90.0 mg, 60.3 mg, 5.0 mg, 37.5 mg, 3.8 mg/mL, 1.9 mg/mL, 0.04 mg/mg, 62.5 mg, 115.0 mg, 0.03846 mg/mg, 0.00421 mg/mg, 0.0532 mg/mg, 300.0 mg, 166.67 mg, 150.0 mg, 70.0 mg, 166.0 mg, 0.01 mg/mg, 240.0 mg/mL, 165.0 mg, 166.6 mg, 30.0 mg/mL, 252.0 mg, 133.3 mg, 87.5 mg, 62.0 mg, 66.67 mg, 20.0 mg/mL, 72.75 mg, 142.5 mg
, Tablet, Oral, Tablet - Oral, Tablet, coated - Oral, Tablet, coated, Kit, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Powder, for solution, Powder, for solution - Oral, Capsule - Oral, Capsule, Powder, metered - Oral, Powder, metered, Irrigation, Solution - Irrigation, Solution, Liquid - Irrigation, Liquid, Tablet, chewable, Tablet, extended release - Oral, Tablet, extended release, Tablet, chewable - Oral, Liquid - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit - Oral, Wafer - Oral, Wafer, Capsule, liquid filled, Capsule, liquid filled - Oral, Pill, Pill - Oral, Powder, Powder - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Oral; Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Bowel preparation therapy
400.0 mg, , 253.0 mg, 75.0 mg, 25.0 mg, 45.0 mg, 30.0 mg, 3500.0 mg, 250.0 mg, 241.8 mg, 50.0 mg, 82.0 mg, 410.0 mg, 420.0 mg, 100.0 mg, 136.0 mg, 167.0 mg, 133.0 mg, 82.9 mg, 96.9 mg, 96.95 mg, 63.0 mg, 0.35 mg/mg, 60.0 mg, 0.5 mg/mg, 170.0 mg, 10.0 mg, 66.6 mg, 155.0 mg, 663.0 mg, 600.0 mg, 84.0 mg, 140.0 mg, 125.0 mg, 500.0 mg, 200.0 mg, 35.0 mg/mL, 15.0 mg, 20.0 mg, 0.03 mg, 12.0 mg/mL, 40.0 mg, 10.0 mg/mL, 1.0 mg/mg, 158.0 mg, 0.005 mg, 35.0 mg, 90.0 mg, 60.3 mg, 5.0 mg, 37.5 mg, 3.8 mg/mL, 1.9 mg/mL, 0.04 mg/mg, 62.5 mg, 115.0 mg, 0.03846 mg/mg, 0.00421 mg/mg, 0.0532 mg/mg, 300.0 mg, 166.67 mg, 150.0 mg, 70.0 mg, 166.0 mg, 0.01 mg/mg, 240.0 mg/mL, 165.0 mg, 166.6 mg, 30.0 mg/mL, 252.0 mg, 133.3 mg, 87.5 mg, 62.0 mg, 66.67 mg, 20.0 mg/mL, 72.75 mg, 142.5 mg
, Tablet, Oral, Tablet - Oral, Tablet, coated - Oral, Tablet, coated, Kit, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Powder, for solution, Powder, for solution - Oral, Capsule - Oral, Capsule, Powder, metered - Oral, Powder, metered, Irrigation, Solution - Irrigation, Solution, Liquid - Irrigation, Liquid, Tablet, chewable, Tablet, extended release - Oral, Tablet, extended release, Tablet, chewable - Oral, Liquid - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit - Oral, Wafer - Oral, Wafer, Capsule, liquid filled, Capsule, liquid filled - Oral, Pill, Pill - Oral, Powder, Powder - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Oral; Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Heartburn
400.0 mg, , 253.0 mg, 75.0 mg, 25.0 mg, 45.0 mg, 30.0 mg, 3500.0 mg, 250.0 mg, 241.8 mg, 50.0 mg, 82.0 mg, 410.0 mg, 420.0 mg, 100.0 mg, 136.0 mg, 167.0 mg, 133.0 mg, 82.9 mg, 96.9 mg, 96.95 mg, 63.0 mg, 0.35 mg/mg, 60.0 mg, 0.5 mg/mg, 170.0 mg, 10.0 mg, 66.6 mg, 155.0 mg, 663.0 mg, 600.0 mg, 84.0 mg, 140.0 mg, 125.0 mg, 500.0 mg, 200.0 mg, 35.0 mg/mL, 15.0 mg, 20.0 mg, 0.03 mg, 12.0 mg/mL, 40.0 mg, 10.0 mg/mL, 1.0 mg/mg, 158.0 mg, 0.005 mg, 35.0 mg, 90.0 mg, 60.3 mg, 5.0 mg, 37.5 mg, 3.8 mg/mL, 1.9 mg/mL, 0.04 mg/mg, 62.5 mg, 115.0 mg, 0.03846 mg/mg, 0.00421 mg/mg, 0.0532 mg/mg, 300.0 mg, 166.67 mg, 150.0 mg, 70.0 mg, 166.0 mg, 0.01 mg/mg, 240.0 mg/mL, 165.0 mg, 166.6 mg, 30.0 mg/mL, 252.0 mg, 133.3 mg, 87.5 mg, 62.0 mg, 66.67 mg, 20.0 mg/mL, 72.75 mg, 142.5 mg
, Tablet, Oral, Tablet - Oral, Tablet, coated - Oral, Tablet, coated, Kit, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Powder, for solution, Powder, for solution - Oral, Capsule - Oral, Capsule, Powder, metered - Oral, Powder, metered, Irrigation, Solution - Irrigation, Solution, Liquid - Irrigation, Liquid, Tablet, chewable, Tablet, extended release - Oral, Tablet, extended release, Tablet, chewable - Oral, Liquid - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit - Oral, Wafer - Oral, Wafer, Capsule, liquid filled, Capsule, liquid filled - Oral, Pill, Pill - Oral, Powder, Powder - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Oral; Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Warnings
There are 20 known major drug interactions with Clenpiq.Common Clenpiq Drug Interactions
Drug Name
Risk Level
Description
2,5-Dimethoxy-4-ethylamphetamine
Major
The serum concentration of 2,5-Dimethoxy-4-ethylamphetamine can be increased when it is combined with Magnesium oxide.
2,5-Dimethoxy-4-ethylthioamphetamine
Major
The serum concentration of 2,5-Dimethoxy-4-ethylthioamphetamine can be increased when it is combined with Magnesium oxide.
4-Bromo-2,5-dimethoxyamphetamine
Major
The serum concentration of 4-Bromo-2,5-dimethoxyamphetamine can be increased when it is combined with Magnesium oxide.
Amphetamine
Major
The serum concentration of Amphetamine can be increased when it is combined with Magnesium oxide.
Atazanavir
Major
Magnesium oxide can cause a decrease in the absorption of Atazanavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Clenpiq Novel Uses: Which Conditions Have a Clinical Trial Featuring Clenpiq?
6 active clinical trials are assessing the potential of Clenpiq to reduce Heartburn, facilitate Bowel preparation therapy and promote Nutritional supplementation.Condition
Clinical Trials
Trial Phases
Indigestion
13 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 2, Phase 1, Phase 4
Heartburn
2 Actively Recruiting
Phase 3, Not Applicable
Bowel preparation therapy
2 Actively Recruiting
Phase 1, Phase 2, Not Applicable
Nutritional supplementation
1 Actively Recruiting
Early Phase 1
Clenpiq Reviews: What are patients saying about Clenpiq?
5Patient Review
6/9/2022 I'm an experienced user, and I have to say that Clenpiq was great! Easy to use and no cramping. Would recommend it to anyone.
5Patient Review
7/15/2022 The prep for this was easy to take and follow. I wasn't hungry or feeling any negative effects like a headache from dehydration, which was great.
3.3Patient Review
6/22/2022 This did a great job at cleansing my bowels for colonoscopy, but I didn't love the taste. It's very salty and bitter, not sweet like some people said. I had to drink it quickly and chase each gulp with apple juice, which made me a little nauseous.
3Patient Review
10/18/2022 The containers were very difficult to open. The taste and texture were also pretty bad, but I'm glad the nurse warned me to sip it slowly and alternate with tea or broth. I didn't get a full clean-out, but the doctor said it was okay.
2Patient Review
10/28/2022 I don't think I can ever drink this again. It was the most awful tasting drink. I was gagging even though I chased it with sweet tea. Ended up throwing up about 5 times.
2Patient Review
10/23/2022 The only good things about this product are the bottle shape and flavoring. It took hours before I saw any results, and then it dragged on for even longer. My insurance made me use this as it would not cover Suprep any longer, but next time I will pay out of pocket. Suprep works in 30 minutes and is done within 2 hours. With Clenpiq I wasn't even fully clear after the entire prep.
1.7Patient Review
7/31/2022 Clenpiq was awful! It tastes like concentrated cough syrup. I could taste it in my throat, tongue, and teeth—I almost threw up. But I knew I needed it, so I choked it down. And then I realized I had a whole new bottle to drink! There's got to be an easier way. No wonder people put their colonoscopies off!
1.7Patient Review
10/31/2022 The prep for this was really tough to go through. I found that Miralax mixed with juice was a better method and worked much faster. The bottle says cranberry flavor but it tasted nothing like it.
1.7Patient Review
8/4/2022 Clenpiq was a total nightmare for me. I lost all control after taking it and it's still affecting me months later. Avoid if you can.
Patient Q&A Section about clenpiq
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How long do you poop with Clenpiq?
"— Some people will have multiple urgent bowel movements within 30 minutes of drinking the solution and others may not have a bowel movement for 3-4 hours."
Answered by AI
How fast should you drink Clenpiq?
"Drink one bottle of CLENPIQ, then drink one cup (8-ounces each) of clear liquid every 15 minutes for at least four cups. You may continue drinking clear liquids up to 3 hours before your exam."
Answered by AI
Is Clenpiq a good bowel prep?
"Of the 231 people who rated Clenpiq, the average rating was 5.9 out of 10."
Answered by AI
Does Clenpiq make you throw up?
"If you start to feel nauseous or vomit, drink the solution more slowly. Try to drink all of it even if it takes longer. If vomiting continues, or you can't finish the preparation, stop taking it and call your doctor's office for further instructions."
Answered by AI