Citanest
Local Anaesthesia therapy
Treatment
1 FDA approval
0 Active Studies for Citanest
Treatment for
Local Anaesthesia therapy
What is Citanest
Prilocaine
The Generic name of this drug
Treatment Summary
Epinephrine, also known as adrenaline, is a hormone produced by the adrenal glands that has a variety of important functions. It has been used to treat allergies and other hypersensitivity reactions since 1987, and a generic form of epinephrine auto-injector was approved in 2018. Epinephrine can be administered intravenously, inhalation, nebulization, intramuscular injection, and subcutaneous injection. The most common uses are to relieve respiratory distress due to bronchospasm, to provide rapid relief of allergies and other hypersensitivity reactions, and to prolong the action of infiltration anesthetics. It is
Citanest Forte
is the brand name
Citanest Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Citanest Forte
Prilocaine
1965
73
Approved as Treatment by the FDA
Prilocaine, also known as Citanest Forte, is approved by the FDA for 1 uses such as Local Anaesthesia therapy .
Local Anaesthesia therapy
Effectiveness
How Citanest Affects Patients
Epinephrine is a drug that has effects similar to those of the body's own nerve system. It can increase heart rate, make the heart pump more strongly, and cause the body to produce more of a hormone that helps regulate blood pressure. Epinephrine can also help open the airways in the lungs, relax muscles in the uterus, and reduce itching, hives, and swelling caused by an allergic reaction. It may also help with digestive and urinary symptoms related to an allergic reaction.
How Citanest works in the body
Epinephrine works on two types of receptors in the body, alpha and beta. It reduces the widenening of blood vessels and the loss of fluid caused by allergic reactions, and it also works as an antihistamine. It increases the amount of sugar in the blood, and relaxes the muscles of the bronchial tubes and iris. This helps with breathing, wheezing, and any other reactions caused by allergies.
When to interrupt dosage
The quantity of Citanest is reliant upon the diagnosed affliction, including Asthma, Angioneurotic Edema and Idiopathic Anaphylaxis. The dosage can be found in the table below, depending on the method of administration.
Condition
Dosage
Administration
Local Anaesthesia therapy
, 40.0 mg/mL, 0.025 mg/mg, 2.5 %, 50.0 mg/mL, 2.5 mg/mg, 0.05 mg/mg
, Injection, solution, Subcutaneous, Injection, solution - Subcutaneous, Cream, Cream - Topical, Topical, Periodontal, Gel - Periodontal, Injection, solution - Dental, Dental, Gel, Kit, Kit - Topical, Infiltration, Gel - Topical, Solution - Infiltration, Solution, Spray, Spray - Cutaneous, Cutaneous, Patch, Patch - Topical, Submucosal, Injection, solution - Submucosal, Parenteral, Injection, solution - Parenteral, Ointment, Ointment - Topical, Intra-articular; Intramuscular; Topical, Cream; Kit, Cream; Kit - Topical, Kit - Cutaneous; Topical, Cutaneous; Topical, Oral; Topical
Warnings
Citanest has eight acknowledged contraindications, so it should not be utilized when dealing with the conditions in the following table.
Citanest Contraindications
Condition
Risk Level
Notes
Methemoglobinemia
Do Not Combine
Congenital methaemoglobinaemia
Do Not Combine
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Citanest.
Common Citanest Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Ethanol
Major
Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Oliceridine
Major
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Prilocaine is combined with Oliceridine.
Technetium Tc-99m tilmanocept
Major
Prilocaine may decrease effectiveness of Technetium Tc-99m tilmanocept as a diagnostic agent.
Thalidomide
Major
Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Citanest Toxicity & Overdose Risk
Epinephrine can be dangerous when taken in large doses and can cause anxiety, headaches, fear, palpitations, and necrosis at the injection site. It can also affect heart rate and blood pressure, leading to angina, ischemia, or aortic rupture. Overdosing on epinephrine can cause cerebral hemorrhage, hemiplegia, subarachnoid hemorrhage, anginal pain, anxiety, restlessness, throbbing headache, tremor, weakness, dizziness, pallor, respiratory difficulty, palpitation, apprehensiveness, sweating, nausea, vomiting, cardiac arrhythmias,
Citanest Novel Uses: Which Conditions Have a Clinical Trial Featuring Citanest?
282 active studies are underway to assess the potential of Citanest to reduce the symptoms of Asthma, Allergy and Laryngotracheobronchitis.
Condition
Clinical Trials
Trial Phases
Local Anaesthesia therapy
0 Actively Recruiting
Citanest Reviews: What are patients saying about Citanest?
5
Patient Review
8/30/2011
Citanest for Administration of Local Anesthetic Drug
Patient Q&A Section about citanest
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
How long does Citanest last?
"Citanest is a long-lasting, low-toxicity anesthetic that is versatile and suitable for single unit crown procedures. It provides complete anesthesia for procedures lasting an average of 1 hour. Citanest is also versatile, providing anesthesia for both infiltration and nerve block techniques."
Answered by AI
What is Citanest used for?
"Citanest Plain Dental Injection is only indicated for the production of local anesthesia in dentistry by nerve block or infiltration techniques if these procedures are described in standard textbooks."
Answered by AI
Does Citanest contain epinephrine?
"This product is a sterile, non-pyrogenic, isotonic solution that contains a local anesthetic agent with epinephrine and is administered parenterally by injection. It is indicated for use in dental procedures."
Answered by AI
What is Citanest with Octapressin?
"Citanest DENTAL with Octapressin is a local anesthetic used to prevent or relieve pain during dental procedures. It is injected into the gums and works by blocking nerves from sending pain messages to the brain."
Answered by AI