Celexa

Obsessive-Compulsive Disorder, Premenstrual Dysphoric Disorder, Social Anxiety Disorder + 8 more
Treatment
1 FDA approval
20 Active Studies for Celexa

What is Celexa

CitalopramThe Generic name of this drug
Treatment SummaryCitalopram is a type of antidepressant called a selective serotonin-reuptake inhibitor (SSRI). It is used to treat the symptoms of depression and is available in tablet and liquid form. This drug was approved by the FDA in 1998 and is commonly known by the name Celexa.
Citalopram Hydrobromideis the brand name
Celexa Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Citalopram Hydrobromide
Citalopram
1998
418

Approved as Treatment by the FDA

Citalopram, also known as Citalopram Hydrobromide, is approved by the FDA for 1 uses like Depression .
Depression
Helps manage Depression

Effectiveness

How Celexa Affects PatientsCitalopram is an antidepressant that belongs to a group of medications known as selective serotonin reuptake inhibitors (SSRIs). It can help treat symptoms of depression, anxiety, eating disorders, and obsessive-compulsive disorder. It works by blocking the reabsorption of serotonin in the brain, which helps regulate mood, perception, reward, anger, aggression, appetite, memory, sexuality, and attention. Citalopram usually begins to take effect in 1-4 weeks, with full effects usually taking 8-12 weeks. In addition, citalopram does not inhibit the enzyme monoamine oxidase.
How Celexa works in the bodyCitalopram works by blocking the nerve cells in the brain from absorbing serotonin. It specifically targets serotonin transporter proteins, which are responsible for re-absorbing serotonin from the nerves. Citalopram does not have a strong effect on other types of receptors, so it has fewer side effects than other similar drugs. It does not affect dopamine, adrenaline, histamine, or GABA receptors, which are responsible for many of the negative side effects of other medications.

When to interrupt dosage

The proposed measure of Celexa is contingent upon the observed condition, including Obsessive-Compulsive Disorder, Premenstrual Dysphoric Disorder and Diabetic Neuropathy. The amount additionally fluctuates based on the mode of delivery (e.g. Tablet - Oral or Tablet) featured in the table beneath.
Condition
Dosage
Administration
Premature Ejaculation
20.0 mg, 40.0 mg, , 2.0 mg/mL, 10.0 mg, 10.0 mg/mL, 30.0 mg, 0.4 mg
Tablet - Oral, Tablet, Solution - Oral, Capsule - Oral, Tablet, film coated - Oral, , Oral, Tablet, film coated, Solution, Capsule, Kit
Obsessive-Compulsive Disorder
20.0 mg, 40.0 mg, , 2.0 mg/mL, 10.0 mg, 10.0 mg/mL, 30.0 mg, 0.4 mg
Tablet - Oral, Tablet, Solution - Oral, Capsule - Oral, Tablet, film coated - Oral, , Oral, Tablet, film coated, Solution, Capsule, Kit
Premenstrual Dysphoric Disorder
20.0 mg, 40.0 mg, , 2.0 mg/mL, 10.0 mg, 10.0 mg/mL, 30.0 mg, 0.4 mg
Tablet - Oral, Tablet, Solution - Oral, Capsule - Oral, Tablet, film coated - Oral, , Oral, Tablet, film coated, Solution, Capsule, Kit
Social Anxiety Disorder
20.0 mg, 40.0 mg, , 2.0 mg/mL, 10.0 mg, 10.0 mg/mL, 30.0 mg, 0.4 mg
Tablet - Oral, Tablet, Solution - Oral, Capsule - Oral, Tablet, film coated - Oral, , Oral, Tablet, film coated, Solution, Capsule, Kit
Diabetic Neuropathy
20.0 mg, 40.0 mg, , 2.0 mg/mL, 10.0 mg, 10.0 mg/mL, 30.0 mg, 0.4 mg
Tablet - Oral, Tablet, Solution - Oral, Capsule - Oral, Tablet, film coated - Oral, , Oral, Tablet, film coated, Solution, Capsule, Kit
Post Traumatic Stress Disorder
20.0 mg, 40.0 mg, , 2.0 mg/mL, 10.0 mg, 10.0 mg/mL, 30.0 mg, 0.4 mg
Tablet - Oral, Tablet, Solution - Oral, Capsule - Oral, Tablet, film coated - Oral, , Oral, Tablet, film coated, Solution, Capsule, Kit
Generalized Anxiety Disorder
20.0 mg, 40.0 mg, , 2.0 mg/mL, 10.0 mg, 10.0 mg/mL, 30.0 mg, 0.4 mg
Tablet - Oral, Tablet, Solution - Oral, Capsule - Oral, Tablet, film coated - Oral, , Oral, Tablet, film coated, Solution, Capsule, Kit
Bulimia Nervosa
20.0 mg, 40.0 mg, , 2.0 mg/mL, 10.0 mg, 10.0 mg/mL, 30.0 mg, 0.4 mg
Tablet - Oral, Tablet, Solution - Oral, Capsule - Oral, Tablet, film coated - Oral, , Oral, Tablet, film coated, Solution, Capsule, Kit
Depression
20.0 mg, 40.0 mg, , 2.0 mg/mL, 10.0 mg, 10.0 mg/mL, 30.0 mg, 0.4 mg
Tablet - Oral, Tablet, Solution - Oral, Capsule - Oral, Tablet, film coated - Oral, , Oral, Tablet, film coated, Solution, Capsule, Kit
Anorexia Nervosa
20.0 mg, 40.0 mg, , 2.0 mg/mL, 10.0 mg, 10.0 mg/mL, 30.0 mg, 0.4 mg
Tablet - Oral, Tablet, Solution - Oral, Capsule - Oral, Tablet, film coated - Oral, , Oral, Tablet, film coated, Solution, Capsule, Kit
Panic Disorder
20.0 mg, 40.0 mg, , 2.0 mg/mL, 10.0 mg, 10.0 mg/mL, 30.0 mg, 0.4 mg
Tablet - Oral, Tablet, Solution - Oral, Capsule - Oral, Tablet, film coated - Oral, , Oral, Tablet, film coated, Solution, Capsule, Kit

Warnings

Celexa Contraindications
Condition
Risk Level
Notes
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Citalopram may interact with Toxoplasma Infections
There are 20 known major drug interactions with Celexa.
Common Celexa Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be decreased when combined with Citalopram.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be decreased when combined with Citalopram.
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Citalopram.
Aminophylline
Major
The metabolism of Aminophylline can be decreased when combined with Citalopram.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Citalopram.
Celexa Toxicity & Overdose RiskThe lethal dose of citalopram in humans is 56mg/kg and 179mg/kg in mice. Symptoms of an overdose can include dizziness, sweating, nausea, vomiting, trembling, drowsiness, fast heart rate, and confusion. In rare cases, amnesia, coma, seizures, shortness of breath, muscle breakdown, and abnormal heart rhythms may occur. If an overdose occurs, supportive care should be provided and activated charcoal and vomiting may be used. This drug is considered to be of a pregnancy category C and should only be used if the potential benefits outweigh the possible risks to the fetus. Citalopram

Celexa Novel Uses: Which Conditions Have a Clinical Trial Featuring Celexa?

954 clinical trials are currently being conducted to evaluate the potential of Celexa in treating Panic Disorder, Obsessive-Compulsive Disorder and Depression.
Condition
Clinical Trials
Trial Phases
Panic Disorder
17 Actively Recruiting
Not Applicable, Phase 3, Phase 1, Phase 2
Obsessive-Compulsive Disorder
15 Actively Recruiting
Not Applicable, Phase 3
Depression
642 Actively Recruiting
Phase 2, Not Applicable, Phase 3, Phase 1, Early Phase 1, Phase 4
Post Traumatic Stress Disorder
242 Actively Recruiting
Phase 4, Phase 1, Not Applicable, Early Phase 1, Phase 2, Phase 3
Social Anxiety Disorder
25 Actively Recruiting
Not Applicable, Phase 3, Phase 2, Phase 4
Bulimia Nervosa
14 Actively Recruiting
Not Applicable, Phase 2, Phase 3, Early Phase 1
Premenstrual Dysphoric Disorder
0 Actively Recruiting
Diabetic Neuropathy
17 Actively Recruiting
Phase 2, Not Applicable, Phase 3, Early Phase 1
Premature Ejaculation
0 Actively Recruiting
Generalized Anxiety Disorder
34 Actively Recruiting
Not Applicable, Phase 3, Phase 2, Phase 1
Anorexia Nervosa
0 Actively Recruiting

Celexa Reviews: What are patients saying about Celexa?

5Patient Review
4/25/2021
Celexa for Repeated Episodes of Anxiety
Celexa has been a total game-changer for me. I was having anxiety attacks that I couldn't control, but after starting this medication, they stopped completely. Not to mention my heart palpitations calmed down and my mood improved. Would definitely recommend!
5Patient Review
10/18/2021
Celexa for Depression
This medication has helped me a lot with my memory. I was having trouble remembering simple words or using the wrong ones, but that's no longer an issue.
5Patient Review
2/28/2022
Celexa for Posttraumatic Stress Syndrome
Celexa has really helped me with my depression. I didn't notice a difference until after the first month, but by the third month I could really tell that things had changed for the better. If you're struggling with depression, I would recommend giving this medication a try.
5Patient Review
3/10/2022
Celexa for Depression
I've been taking Celexa for nearly two decades and it has vastly improved the quality of my life. I only wish I had started sooner!
4.3Patient Review
5/13/2022
Celexa for Depression
I found this medication to be really helpful at first, but then it just stopped working for me. In fact, it made me feel worse so I had to stop taking it.
3.7Patient Review
4/15/2022
Celexa for Anxiousness associated with Depression
I didn't experience the results I was hoping for.
3.7Patient Review
5/24/2022
Celexa for Anxiousness associated with Depression
I found that this medication helped to improve my mood and patience. It's also been effective in managing my anxiety and depression. The only downside is that I experienced some mild gastrointestinal side effects when I first started taking it.
2.7Patient Review
12/16/2019
Celexa for Depression
I was switched to Celexa after Cipralex stopped working for me. Unfortunately, Celexa has made me sweat and I can't get a full night's sleep.
2.3Patient Review
1/7/2020
Celexa for Depression
I felt like the depression was at bay, but it made my anxiety skyrocket. The side effects were extreme—either not enough sleep or I’d sleep the entire day, always felt unwell and nauseous, horrible headaches. I’m currently on week three of coming off of 20mg, and I keep forgetting simple words or use the wrong ones (completely out of my character)..!
2.3Patient Review
10/15/2020
Celexa for Bipolar Depression
I had really bad side effects from Celexa, to the point where I started harming myself. Never again will I take this medication.
1Patient Review
9/20/2020
Celexa for Depression
I started taking Celexa 10 mg. for depression two weeks ago and have since then only experienced negative side effects such as terrible headaches and nausea.

Patient Q&A Section about celexa

Is Celexa better than Zoloft?

"A study was done comparing the effects of two drugs for treating depression. The study found that both drugs were effective and tolerated well. However, Celexa showed earlier signs of symptom improvement than Zoloft." - Anonymous Online Contributor

Unverified Answer

Is Celexa similar to Xanax?

"Celexa (citalopram) and Xanax are not the same medication. They might have some of the same side effects, but they belong to different medication classes. Celexa is a selective serotonin reuptake inhibitor (SSRI), while Xanax is a benzodiazepine." - Anonymous Online Contributor

Unverified Answer

Is Celexa better for anxiety or depression?

"Celexa is a selective serotonin reuptake inhibitor (SSRI) and Xanax is a benzodiazepine.

Celexa and Xanax are two different drugs that are used to treat anxiety. Celexa is an SSRI that is primarily used to treat depression, but it can also be used to treat anxiety. Xanax is a benzodiazepine that is also used to treat panic attacks." - Anonymous Online Contributor

Unverified Answer

What does Celexa do to you?

"Celexa is a medication that helps to elevate serotonin levels in the brain. Serotonin is a hormone that can impact sleep, metabolism, and mood. Low serotonin levels have been linked by research to both depression and anxiety. Celexa is typically taken once a day, either in the morning or evening, and can be taken with or without food." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Clinical Trials for Celexa

Image of Icahn School of Medicine at Mount Sinai, Mount Sinai West in New York, United States.
Phase-Based Progress Estimates
1
Effectiveness
1
Safety

Deep Brain Stimulation (DBS) For Treatment Resistant Depressionfor Major Depressive Disorder

25 - 70
All Sexes
New York, NY
Of the estimated 30 million Americans who suffer from Major Depressive Disorder, approximately 10% are considered treatment resistant. Deep brain stimulation (DBS) to a region of the brain called the subcallosal cingulate (SCC) is an emerging strategy for treatment resistant depression (TRD), which involves placement of electrodes in a specific region of the brain and stimulating that area with electricity. This is believed to reset the brain network responsible for symptoms and results in a significant antidepressant response. A series of open-label studies have demonstrated sustained, long-term antidepressant effects in 40-60% of patients who received this treatment. A challenge to the effective dissemination of this fledgling treatment is the absence of biomarkers (objective, measureable indications of the state of the body and brain) to guide device placement and select stimulation parameters during follow-up care. By using a DBS device called the Percept PC (Medtronic, Inc) which has the ability to both deliver stimulation to and record electrical signals directly from the brain, this study aims to identify changes in local field potentials (LFPs), specific electrical signals that are thought to represent how the brain communicates information from one region to another, to see how this relates to DBS parameter settings and patient depressive symptomatology. The goal of this study is to study LFPs before and during active DBS stimulation to identify changes that correlate with the antidepressant effects of SCC DBS. The study team will recruit 10 patients with TRD and implant them with the Percept PC system. Participants will be asked to complete short questionnaires and collect LFP data twice daily for the first year of the study, as well as have weekly in person research procedures and assessments with the study team for up to one year. These include meetings with the study psychiatrist, psychologist, symptom ratings, and movement, voice, and video recordings. A brief discontinuation experiment will be conducted after 6 months of stimulation, in which the stimulation will be turned off and patterns of LFP changes will be recorded. The entire study is expected to last about 5 years, parcellated into several study phases. All participants are required to live in the New York metropolitan area for the first several months of the study.
Recruiting
Has No Placebo
Icahn School of Medicine at Mount Sinai, Mount Sinai WestHelen Mayberg, MD
Have you considered Celexa clinical trials? We made a collection of clinical trials featuring Celexa, we think they might fit your search criteria.
Have you considered Celexa clinical trials? We made a collection of clinical trials featuring Celexa, we think they might fit your search criteria.
Have you considered Celexa clinical trials? We made a collection of clinical trials featuring Celexa, we think they might fit your search criteria.
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