Calcium Acetate

Hyperphosphataemia, Communicable Diseases, Dialysis therapy + 4 more
Treatment
3 FDA approvals
5 Active Studies for Calcium Acetate

What is Calcium Acetate

Calcium acetateThe Generic name of this drug
Treatment SummaryCalcium acetate is a compound made from calcium and acetic acid (vinegar). It is usually sold as the monohydrate form, which absorbs water easily. It is also known as the acetate of lime.
ProcalAmineis the brand name
Calcium Acetate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
ProcalAmine
Calcium acetate
1982
77

Approved as Treatment by the FDA

Calcium acetate, otherwise known as ProcalAmine, is approved by the FDA for 3 uses which include Kidney Failure, Chronic and End-stage Renal Failure (ESRF) .
Kidney Failure, Chronic
Helps manage End-stage Renal Failure (ESRF)
End-stage Renal Failure (ESRF)
Helps manage End-stage Renal Failure (ESRF)
Hyperphosphataemia
Helps manage Hyperphosphataemia

Effectiveness

How Calcium Acetate Affects PatientsFor people with kidney problems, their body may not be able to get rid of phosphate properly. This can cause high levels of phosphate in the body which can lead to bone and tissue damage. To lower the amount of phosphate, people may need to reduce the amount they eat, use dialysis, or take a medicine called calcium acetate. Calcium acetate binds to phosphate in the gut and helps it pass out of the body in the feces. By taking calcium acetate, the amount of phosphate in the body can be kept below 6.0 mg/dl.
How Calcium Acetate works in the bodyCalcium acetate helps to get rid of extra phosphorus in your body. It does this by binding with the phosphorus in the food you eat. This prevents it from being absorbed and instead causes it to be eliminated from the body.

When to interrupt dosage

The recommended dosage of Calcium Acetate is contingent upon the ascertained condition, such as Kidney, Hyperphosphataemia and Kidney Failure, Chronic. The required amount of dosage is delineated in the table beneath, with regards to the method of administration (e.g. Intravenous or Topical).
Condition
Dosage
Administration
Kidney
667.0 mg, , 667.0 mg/mL, 0.839 mg/mg, 0.952 mg/mg, 952.0 mg, 5.95 mg/mL, 450.0 mg, 300.0 mg, 668.0 mg, 0.26 mg/mL, 22.0 mg/mL, 6.67 mg/mg, 44.0 mg/mL
, Oral, Tablet - Oral, Tablet, Capsule - Oral, Capsule, Solution, Solution - Oral, Powder, for solution - Topical, Topical, Powder, for solution, Solution - Topical, Intravenous, Injection, Injection - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid, Liquid - Intravenous, Solution - Intravenous, Tablet, coated, Tablet, coated - Oral
Hyperphosphataemia
667.0 mg, , 667.0 mg/mL, 0.839 mg/mg, 0.952 mg/mg, 952.0 mg, 5.95 mg/mL, 450.0 mg, 300.0 mg, 668.0 mg, 0.26 mg/mL, 22.0 mg/mL, 6.67 mg/mg, 44.0 mg/mL
, Oral, Tablet - Oral, Tablet, Capsule - Oral, Capsule, Solution, Solution - Oral, Powder, for solution - Topical, Topical, Powder, for solution, Solution - Topical, Intravenous, Injection, Injection - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid, Liquid - Intravenous, Solution - Intravenous, Tablet, coated, Tablet, coated - Oral
high phosphate levels
667.0 mg, , 667.0 mg/mL, 0.839 mg/mg, 0.952 mg/mg, 952.0 mg, 5.95 mg/mL, 450.0 mg, 300.0 mg, 668.0 mg, 0.26 mg/mL, 22.0 mg/mL, 6.67 mg/mg, 44.0 mg/mL
, Oral, Tablet - Oral, Tablet, Capsule - Oral, Capsule, Solution, Solution - Oral, Powder, for solution - Topical, Topical, Powder, for solution, Solution - Topical, Intravenous, Injection, Injection - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid, Liquid - Intravenous, Solution - Intravenous, Tablet, coated, Tablet, coated - Oral
Astringent
667.0 mg, , 667.0 mg/mL, 0.839 mg/mg, 0.952 mg/mg, 952.0 mg, 5.95 mg/mL, 450.0 mg, 300.0 mg, 668.0 mg, 0.26 mg/mL, 22.0 mg/mL, 6.67 mg/mg, 44.0 mg/mL
, Oral, Tablet - Oral, Tablet, Capsule - Oral, Capsule, Solution, Solution - Oral, Powder, for solution - Topical, Topical, Powder, for solution, Solution - Topical, Intravenous, Injection, Injection - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid, Liquid - Intravenous, Solution - Intravenous, Tablet, coated, Tablet, coated - Oral
Communicable Diseases
667.0 mg, , 667.0 mg/mL, 0.839 mg/mg, 0.952 mg/mg, 952.0 mg, 5.95 mg/mL, 450.0 mg, 300.0 mg, 668.0 mg, 0.26 mg/mL, 22.0 mg/mL, 6.67 mg/mg, 44.0 mg/mL
, Oral, Tablet - Oral, Tablet, Capsule - Oral, Capsule, Solution, Solution - Oral, Powder, for solution - Topical, Topical, Powder, for solution, Solution - Topical, Intravenous, Injection, Injection - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid, Liquid - Intravenous, Solution - Intravenous, Tablet, coated, Tablet, coated - Oral
Dialysis therapy
667.0 mg, , 667.0 mg/mL, 0.839 mg/mg, 0.952 mg/mg, 952.0 mg, 5.95 mg/mL, 450.0 mg, 300.0 mg, 668.0 mg, 0.26 mg/mL, 22.0 mg/mL, 6.67 mg/mg, 44.0 mg/mL
, Oral, Tablet - Oral, Tablet, Capsule - Oral, Capsule, Solution, Solution - Oral, Powder, for solution - Topical, Topical, Powder, for solution, Solution - Topical, Intravenous, Injection, Injection - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid, Liquid - Intravenous, Solution - Intravenous, Tablet, coated, Tablet, coated - Oral
Kidney Failure, Chronic
667.0 mg, , 667.0 mg/mL, 0.839 mg/mg, 0.952 mg/mg, 952.0 mg, 5.95 mg/mL, 450.0 mg, 300.0 mg, 668.0 mg, 0.26 mg/mL, 22.0 mg/mL, 6.67 mg/mg, 44.0 mg/mL
, Oral, Tablet - Oral, Tablet, Capsule - Oral, Capsule, Solution, Solution - Oral, Powder, for solution - Topical, Topical, Powder, for solution, Solution - Topical, Intravenous, Injection, Injection - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Liquid, Liquid - Intravenous, Solution - Intravenous, Tablet, coated, Tablet, coated - Oral

Warnings

Calcium Acetate has two restrictions, and it should not be taken in combination with any of the conditions in the following table.Calcium Acetate Contraindications
Condition
Risk Level
Notes
Hypercalcemia
Do Not Combine
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Calcium Acetate.
Common Calcium Acetate Drug Interactions
Drug Name
Risk Level
Description
Technetium Tc-99m oxidronate
Major
Calcium acetate may decrease effectiveness of Technetium Tc-99m oxidronate as a diagnostic agent.
Dobutamine
Minor
The therapeutic efficacy of Dobutamine can be decreased when used in combination with Calcium acetate.
3-Aza-2,3-Dihydrogeranyl Diphosphate
Moderate
Calcium acetate can cause a decrease in the absorption of 3-Aza-2,3-Dihydrogeranyl Diphosphate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Acebutolol
Moderate
The therapeutic efficacy of Acebutolol can be decreased when used in combination with Calcium acetate.
Acetyldigitoxin
Moderate
Calcium acetate may increase the arrhythmogenic and cardiotoxic activities of Acetyldigitoxin.
Calcium Acetate Toxicity & Overdose RiskThe lowest toxic dose of the drug in rats is 4280mg/kg. Mild signs of overdose include constipation, loss of appetite, and nausea and vomiting. In more severe cases, patients may show signs of confusion, unconsciousness, and difficulty speaking.
image of a doctor in a lab doing drug, clinical research

Calcium Acetate Novel Uses: Which Conditions Have a Clinical Trial Featuring Calcium Acetate?

Five active clinical trials are currently being conducted to assess the potential of Calcium Acetate in ameliorating Kidney, high phosphate levels and Hyperphosphataemia.
Condition
Clinical Trials
Trial Phases
high phosphate levels
0 Actively Recruiting
Kidney Failure, Chronic
2 Actively Recruiting
Not Applicable, Phase 1
Communicable Diseases
0 Actively Recruiting
Hyperphosphataemia
0 Actively Recruiting
Dialysis therapy
3 Actively Recruiting
Not Applicable
Astringent
0 Actively Recruiting
Kidney
0 Actively Recruiting

Calcium Acetate Reviews: What are patients saying about Calcium Acetate?

4.7Patient Review
4/14/2010
Calcium Acetate for Renal Osteodystrophy with Hyperphosphatemia
This treatment is great. I'm grateful for modern medicine.
4Patient Review
9/23/2018
Calcium Acetate for High Amount of Phosphate in the Blood
I saw a significant drop in my phosphorus levels after just two weeks of using this treatment. It was easy to use and didn't require any dietary changes, which was great. The only downside is that I have to remember to take it every time I eat, but it's worth it for the relief from itching.
4Patient Review
3/7/2010
Calcium Acetate for High Amount of Phosphate in the Blood
This medication unfortunately caused me a lot of discomfort, including nausea, stomach pain, chest pain, and dizziness. Blurry vision was also an issue. Overall, not a great experience.
3.3Patient Review
11/21/2009
Calcium Acetate for High Amount of Phosphate in the Blood
3Patient Review
11/16/2009
Calcium Acetate for High Amount of Phosphate in the Blood
View All Reviews
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Patient Q&A Section about calcium acetate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who should not take calcium acetate?

"Do not use calcium acetate if you are allergic to it or have high levels of calcium in your blood. Let your doctor know if: your kidney disease gets worse; or you are also taking digoxin (digitalis, Lanoxin)."

Answered by AI

What is another name for calcium acetate?

"There are different brands of calcium acetate, which is a calcium supplement used to control the level of phosphate in the blood for patients on dialysis due to severe kidney disease."

Answered by AI

What is the side effects of calcium acetate?

"The following are symptoms of poisoning: abdominal or stomach pain, full or partial loss of consciousness, headache, incoherent speech, increased urination, metallic taste, muscle weakness, nausea or vomiting."

Answered by AI

When should you take calcium acetate?

"Calcium acetate is a supplement that comes in the form of capsules, tablets, or a liquid solution. It is typically taken with each meal, and people are advised to take it at the same time each day."

Answered by AI

Clinical Trials for Calcium Acetate

Have you considered Calcium Acetate clinical trials? We made a collection of clinical trials featuring Calcium Acetate, we think they might fit your search criteria.
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