Vitamin D Supplementation for Vitamin D Deficiency
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial is testing if giving burn patients with low Vitamin D a higher amount of Vitamin D improves their health more than a smaller amount. The study focuses on physical, mental, and social health outcomes. Vitamin D deficiency is common in burn patients, and previous studies have shown that supplementation may improve health outcomes.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Is vitamin D supplementation safe for humans?
How does the drug Ergocalciferol differ from other vitamin D treatments for deficiency?
Ergocalciferol (vitamin D2) is a synthetic form of vitamin D that is less stable and less potent than cholecalciferol (vitamin D3), which is the natural form found in the body. Unlike vitamin D3, ergocalciferol has a shorter shelf life and is more susceptible to breakdown, making it less effective for long-term supplementation.12367
Who Is on the Research Team?
Maria Pia Kabamalan
Principal Investigator
UT Southwestern
Are You a Good Fit for This Trial?
This trial is for adults with major burn injuries who have a vitamin D deficiency. Eligible participants are those aged 18-64 with burns covering at least 20% of their body, or those aged 65 and older with at least 10% coverage. They must be past the six-month mark from their injury and able to speak English or Spanish. People with cancer, parathyroid disease, severe liver or kidney dysfunction unrelated to burns cannot join.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either a low dose (400 IU) or high dose (4000 IU) of Vitamin D daily
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Ergocalciferol Capsules
Ergocalciferol Capsules is already approved in United States, European Union, Canada for the following indications:
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Texas Southwestern Medical Center
Lead Sponsor