Next-Generation PET Scan Technology Assessment

Michael V Knopp, MD, PhD profile photo
Overseen ByMichael V Knopp, MD, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Cincinnati
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new type of PET scan, a medical imaging technique, to determine if it outperforms current versions. The goal is to explore how advanced digital PET/CT imaging technology can be used in innovative ways beyond typical applications. Suitable candidates for this trial include those diagnosed with a condition requiring exploratory PET imaging. Eligible participants could help improve future medical imaging techniques. As an unphased trial, this study offers a unique opportunity to contribute to groundbreaking research that could redefine medical imaging practices.

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that this PET/CT imaging is safe?

Research shows that digital PET/CT scans are generally easy for people to handle. Studies have found that the radiation from a PET scan is low, about 8 mSv for adults. This level is considered safe and is similar to other common imaging tests, though it does involve some radiation exposure.

The advanced digital PET/CT technology improves image quality and speeds up the process, making the scan faster and possibly more comfortable. No major reports of negative effects from the digital PET/CT scans themselves have emerged.

Overall, digital PET/CT scans have been found safe for patients in similar situations. However, those interested in participating should discuss any concerns with their healthcare provider.12345

Why are researchers excited about this trial?

Researchers are excited about the new-generation digital PET/CT imaging technology because it offers enhanced precision and clarity compared to traditional PET/CT scans. Unlike standard imaging methods, which sometimes struggle with resolution and sensitivity, this cutting-edge technology captures more detailed images, helping doctors detect abnormalities earlier and more accurately. This advancement could lead to better diagnosis and monitoring of diseases, potentially transforming how we understand and treat various medical conditions.

What evidence suggests that this digital PET/CT imaging is effective for new procedures?

Research has shown that the new digital PET/CT imaging technology, which participants in this trial will experience, represents a significant improvement. Studies have found that it produces clearer and more detailed images, aiding doctors in their assessments. It also reduces background noise, enhancing the visibility of important details. One study found that this technology accurately detects various conditions. Compared to older systems, digital PET/CT identifies certain markers more effectively. Overall, these advancements suggest that digital PET/CT imaging could improve the accuracy of diagnosing and assessing conditions.25678

Are You a Good Fit for This Trial?

This trial is for adult men and women who have a medical condition that may benefit from exploratory PET imaging. It's not suitable for pregnant or breastfeeding individuals, prisoners, or those unable to consent or unlikely to complete the procedure.

Inclusion Criteria

I am 18 or older and need a PET scan for my medical condition.

Exclusion Criteria

Participants who are pregnant or lactating
I am unable to give informed consent or unlikely to complete the imaging procedure.
Prisoners

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Investigational PET Imaging

Participants undergo investigational PET/CT imaging using new-generation digital PET technology to assess feasibility and generate preliminary data.

3 years
Multiple visits as required for imaging

Follow-up

Participants are monitored for safety and effectiveness after investigational imaging, and their imaging data may be used for future research.

3 years

What Are the Treatments Tested in This Trial?

Interventions

  • Digital PET/CT imaging
Trial Overview The study is testing the use of a new digital detector technology in PET/CT scans. The goal is to see if this next-generation tech can improve imaging procedures beyond what's currently available.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Investigational ScanExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Cincinnati

Lead Sponsor

Trials
442
Recruited
639,000+

Ohio State University

Lead Sponsor

Trials
891
Recruited
2,659,000+

Ohio Third Frontier

Collaborator

Trials
6
Recruited
690+

Citations

Recent Breakthroughs in PET-CT Multimodality ImagingThe results indicate that HYPER DPR, particularly in digital PET-CT, offers improved spatial resolution, sensitivity, and reduced image noise, ...
Total-Body PET/CT: Challenges and OpportunitiesThis review aims to identify possible challenges and opportunities for PET-centers working with TB and LAFOV systems.
Ultra-fast PET imaging through a combination of digital PET ...The aim of this study was to acquire FDG-PET images with ultra-short acquisition time comparable to a CT scan using a digital PET/CT scanner.
Diagnostic accuracy of the latest-generation digital PET/CT ...Conclusions: In this single-institution study, latest-generation PET/CT had a high sensitivity and moderate to high specificity for detecting ...
Comparison of digital and analog [68Ga]Ga-PSMA-11 PET ...Analog and digital PET/CT showed comparable lesion detection rate (71.8% vs. 74.4%), sensitivity (85.0% vs. 90.0%), and positive predictive ...
PET/CT - Positron Emission Tomography/Computed ...Current and accurate information for patients about PET/CT. Learn what you might experience, how to prepare for the exam, benefits, risks and much more.
Radiation protection of patients during PET/CT scanningThe effective dose from a PET scan is modest and depends on the activity of the injected FDG ( 18 F-Fluoro deoxyglucose) and is typically 8 mSv for adults ...
Radiation Safety With Positron Emission Tomography and ...This article addresses the radiation safety issues posed by PET/CT with regard to the protection and safety of PET/CT personnel, the public, and adult and ...
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