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Bontril
Exogenous Obesity
Treatment
1 FDA approval
0 Active Studies for Bontril
Treatment for
Exogenous Obesity
What is Bontril
PhendimetrazineThe Generic name of this drug
Treatment SummaryPhendimetrazine is a prescription medication used to promote weight loss. It is classified as a Schedule III drug in the US due to its similarity to amphetamines.
Bontril PDMis the brand name
Bontril Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Bontril PDM
Phendimetrazine
1976
79
Approved as Treatment by the FDA
Phendimetrazine, otherwise known as Bontril PDM, is approved by the FDA for 1 uses including Exogenous Obesity .Exogenous Obesity
Helps manage Exogenous Obesity
Effectiveness
How Bontril Affects PatientsPhendimetrazine is a drug that works like the amphetamines used to treat obesity. It stimulates the central nervous system and raises blood pressure. Over time, the body can become used to the drug and it may not be as effective. These drugs are also called "anorectics" and are thought to help with weight loss by reducing appetite, although other effects on the body may also be involved.
How Bontril works in the bodyPhendimetrazine works by activating the body's alpha-adrenergic system, which suppresses appetite and increases metabolism. It also works to release norepinephrine and dopamine. It does this by binding to and reversing the NET, a transport system for these hormones.
When to interrupt dosage
The prescribed measure of Bontril is contingent upon the diagnosed ailment. The amount likewise differs depending on the approach of delivery (e.g. Capsule or Capsule, extended release - Oral) featured in the referenced table.Condition
Dosage
Administration
Exogenous Obesity
, 35.0 mg, 105.0 mg
, Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, Capsule - Oral
Warnings
Bontril has twelve contraindications, thus it should not be ingested if any of the conditions in the table below are present.Bontril ContraindicationsCondition
Risk Level
Notes
Hyperthyroidism
Do Not Combine
Hypertensive disease
Do Not Combine
advanced arteriosclerosis
Do Not Combine
nrevousness
Do Not Combine
symptomatic cardiovascular disease
Do Not Combine
Agitation
Do Not Combine
Hypertension
Do Not Combine
Open-angle glaucoma
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Drug abuse
Do Not Combine
Common Bontril Drug Interactions
Drug Name
Risk Level
Description
1-benzylimidazole
Minor
The therapeutic efficacy of 1-benzylimidazole can be decreased when used in combination with Phendimetrazine.
2,5-Dimethoxy-4-ethylthioamphetamine
Minor
The risk or severity of hypertension can be increased when Phendimetrazine is combined with 2,5-Dimethoxy-4-ethylthioamphetamine.
5-methoxy-N,N-dimethyltryptamine
Minor
The risk or severity of hypertension can be increased when Phendimetrazine is combined with 5-methoxy-N,N-dimethyltryptamine.
Abediterol
Minor
The risk or severity of hypertension can be increased when Phendimetrazine is combined with Abediterol.
Acebutolol
Minor
The therapeutic efficacy of Acebutolol can be decreased when used in combination with Phendimetrazine.
Bontril Toxicity & Overdose RiskTaking too much phendimetrazine can cause restlessness, confusion, aggression, hallucinations, and panic. It can also lead to extreme tiredness and sadness. Heart issues may include abnormal heartbeats, high or low blood pressure, and weak blood circulation. Other symptoms may include nausea, vomiting, diarrhea, and stomach pain. In extreme cases, there may be seizures, unconsciousness, and even death.
Bontril Novel Uses: Which Conditions Have a Clinical Trial Featuring Bontril?
No active trials are currently assessing the potential of Bontril to address Exogenous Obesity.Condition
Clinical Trials
Trial Phases
Exogenous Obesity
0 Actively Recruiting
Bontril Reviews: What are patients saying about Bontril?
5Patient Review
2/7/2009 I started this treatment on 9/30/08 and I was 230lbs. Today is 10/7/2008, and I've already lost 7 lbs. This is the first time something has actually worked for me; I'm really happy about it. Remember that this pill is meant for people who are obese, not just looking to lose 10 pounds. My doctor told me that I have to use it for 3 months, then take a break for 1 month, before starting again.
5Patient Review
6/30/2009 Bontril has been effective for me in losing weight; however, it also makes me feel very irritable. I think this is because it's a stimulant and those typically increase anxiety. So far, the drug has helped with my weight loss goals despite these side effects.
5Patient Review
5/21/2010 I've lost twelve pounds in three weeks thanks to this medication, and I couldn't be happier.
5Patient Review
10/12/2009 I saw significant results within two months.
5Patient Review
11/2/2011 Bontril was extremely effective for me. I lost 20lbs each of the first two months, and then 10lbs in the third month when I took it every other day.
5Patient Review
10/28/2010 Bontril has been a great help to me in losing weight. I'm down 37lbs in just 13 weeks!
5Patient Review
10/29/2019 Bontril has helped me lose weight quickly and effectively. In less than six months, I went from 235 pounds to 179. My doctor was able to lower my insulin intake from 60 units to 16, and my A1C went from 8.5 to 6.8.
5Patient Review
10/29/2019 I've lost a substantial amount of weight in a short period of time with Bontril, and I couldn't be happier. It's worked well for me in conjunction with insulin, and my A1C has improved as a result.
5Patient Review
11/2/2011 Bontril was effective for me in helping to lose weight. I saw the most success when taking it every day for the first two months, then every other day for the third month.
5Patient Review
2/7/2009 I started this treatment on 9/30/08 and I was 230lbs. Today is 10/7/2008 and I have already lost 7lbs. This is the first thing that has ever worked for me and I am very happy. Remember, this pill is for obesity, not just to lose 10 pounds. My doctor told me I have to use it for 3 months then take a break of 1 month and start again...
5Patient Review
11/29/20075Patient Review
8/19/20085Patient Review
11/29/20075Patient Review
8/19/20085Patient Review
6/30/2009 Bontril is assisting me in my weight loss journey, which I am very appreciative of. The only problem I have experienced thus far is that it makes me feel incredibly irritable. This is likely due to it being a stimulant; as those usually lead to increased anxiety levels. Consequently, I have been feeling more emotional and on-edge. Hopefully, these side effects will dissipate soon enough as the drug itself has been helpful.
5Patient Review
10/12/2009 In just two months, I've gone from 247 pounds to 218.
5Patient Review
5/21/2010 I've lost 12lbs in 3 weeks thanks to this medication- 49 more to go!
5Patient Review
10/28/2010 Bontril has been a key part of my weight-loss journey. I've lost 37 pounds in just 13 weeks, and I couldn't be happier.
3.7Patient Review
3/19/2009 The phentermine 37.5 made it hard to work because my heart was racing constantly. So, I called to switch to Bontril and am waiting for that to be more effective. Has anyone else had this problem?
3.7Patient Review
7/3/2009 I was disappointed that I didn't see the same rapid weight loss that others reported. Instead, my weight came off slowly. And now, even after stopping use of the medication months ago, I'm still experiencing racing heart, shortness of breath, and anxiety.
3.7Patient Review
7/3/2009 I slowly lost weight while taking this medication, but have since gained half of it back. I'm also now experiencing racing heart, shortness of breath, and anxiety - even though I stopped taking the medicine months ago. Overall, not a great experience.
3.7Patient Review
3/19/2009 I am currently on phentermine 37.5, but I find it difficult to concentrate at work because my heart rate is always high. I'm going to try Bontril instead and see if that helps. Has anyone else had this problem?
3Patient Review
12/29/2008 I didn't feel as ravenous for the first few days, but now I'm back to normal.
3Patient Review
12/29/2008 For the first few days, I experienced a decreased appetite. Now, however, my hunger is back to its original state.
2.7Patient Review
7/6/2010 I was given this medication to help me lose weight, but it not only failed to do that, it also caused the worst constipation I've ever experienced.
2.7Patient Review
7/6/2010 Bontril didn't help me lose any weight, and made me incredibly constipated to the point where I had to go to the ER.
2.7Patient Review
2/7/20082.7Patient Review
2/7/20082.7Patient Review
7/13/2011 While it didn't help me with appetite or cravings, I appreciate that this treatment exists.
2.7Patient Review
7/13/2011 I didn't find it effective in curbing my appetite or cravings.
2Patient Review
6/19/2013 I had to stop taking this after just two pills because my vision became very blurry. Even now, a month later, it hasn't fully recovered.
2Patient Review
6/19/2013 I had to stop taking this after just two pills because my vision started getting blurry. Even now, about a month later, it hasn't fully recovered.
Patient Q&A Section about bontril
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Does Bontril work for weight loss?
"Phendimetrazine is a drug that is used to help people lose weight by reducing their appetite. It is often used in conjunction with a doctor-approved diet and exercise program."
Answered by AI
Is Bontril still available?
"The Bontril Slow Release product has been discontinued and is no longer available in the United States. If the Food and Drug Administration has approved generic versions of this product, there may be generic equivalents available from other manufacturers."
Answered by AI
What does Bontril do?
"This medication is designed to be used alongside a doctor-approved weight loss plan that includes reducing calorie intake and exercising regularly. It works by suppressing appetite."
Answered by AI
What is the difference between Bontril and phentermine?
"Bontril PDM can help you lose weight, but it shouldn't be used for long periods of time and it isn't for everyone. Adipex-P is effective at lowering appetite and helping with weight loss. Available in generic form, which is more affordable. You only need to take it for a short period of time."
Answered by AI
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