Bontril

Exogenous Obesity

Treatment

1 FDA approval

0 Active Studies for Bontril

Treatment for

Exogenous Obesity

What is Bontril

PhendimetrazineThe Generic name of this drug

Treatment SummaryPhendimetrazine is a prescription medication used to promote weight loss. It is classified as a Schedule III drug in the US due to its similarity to amphetamines.

Bontril PDMis the brand name

image of different drug pills on a surface

Bontril Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Bontril PDM

Phendimetrazine

1976

Approved as Treatment by the FDA

Phendimetrazine, otherwise known as Bontril PDM, is approved by the FDA for 1 uses including Exogenous Obesity .

Exogenous Obesity

Helps manage Exogenous Obesity

Effectiveness

How Bontril Affects PatientsPhendimetrazine is a drug that works like the amphetamines used to treat obesity. It stimulates the central nervous system and raises blood pressure. Over time, the body can become used to the drug and it may not be as effective. These drugs are also called "anorectics" and are thought to help with weight loss by reducing appetite, although other effects on the body may also be involved.

How Bontril works in the bodyPhendimetrazine works by activating the body's alpha-adrenergic system, which suppresses appetite and increases metabolism. It also works to release norepinephrine and dopamine. It does this by binding to and reversing the NET, a transport system for these hormones.

When to interrupt dosage

The prescribed measure of Bontril is contingent upon the diagnosed ailment. The amount likewise differs depending on the approach of delivery (e.g. Capsule or Capsule, extended release - Oral) featured in the referenced table.

Condition

Dosage

Administration

Exogenous Obesity

, 35.0 mg, 105.0 mg

, Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule - Oral, Capsule

Warnings

Bontril has twelve contraindications, thus it should not be ingested if any of the conditions in the table below are present.Bontril Contraindications

Condition

Risk Level

Notes

Hyperthyroidism

Do Not Combine

Hypertensive disease

Do Not Combine

advanced arteriosclerosis

Do Not Combine

nrevousness

Do Not Combine

symptomatic cardiovascular disease

Do Not Combine

Agitation

Do Not Combine

Hypertension

Do Not Combine

Open-angle glaucoma

Do Not Combine

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

Drug abuse

Do Not Combine

There are 20 known major drug interactions with Bontril.

Common Bontril Drug Interactions

Drug Name

Risk Level

Description

1-benzylimidazole

Minor

The therapeutic efficacy of 1-benzylimidazole can be decreased when used in combination with Phendimetrazine.

2,5-Dimethoxy-4-ethylthioamphetamine

Minor

The risk or severity of hypertension can be increased when Phendimetrazine is combined with 2,5-Dimethoxy-4-ethylthioamphetamine.

5-methoxy-N,N-dimethyltryptamine

Minor

The risk or severity of hypertension can be increased when Phendimetrazine is combined with 5-methoxy-N,N-dimethyltryptamine.

Abediterol

Minor

The risk or severity of hypertension can be increased when Phendimetrazine is combined with Abediterol.

Acebutolol

Minor

The therapeutic efficacy of Acebutolol can be decreased when used in combination with Phendimetrazine.

Bontril Toxicity & Overdose RiskTaking too much phendimetrazine can cause restlessness, confusion, aggression, hallucinations, and panic. It can also lead to extreme tiredness and sadness. Heart issues may include abnormal heartbeats, high or low blood pressure, and weak blood circulation. Other symptoms may include nausea, vomiting, diarrhea, and stomach pain. In extreme cases, there may be seizures, unconsciousness, and even death.

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Bontril Novel Uses: Which Conditions Have a Clinical Trial Featuring Bontril?

No active trials are currently assessing the potential of Bontril to address Exogenous Obesity.

Condition

Clinical Trials

Trial Phases

Exogenous Obesity

0 Actively Recruiting

Bontril Reviews: What are patients saying about Bontril?

5Patient Review

2/7/2009

Bontril for Overweight

I started this treatment on 9/30/08 and I was 230lbs. Today is 10/7/2008, and I've already lost 7 lbs. This is the first time something has actually worked for me; I'm really happy about it. Remember that this pill is meant for people who are obese, not just looking to lose 10 pounds. My doctor told me that I have to use it for 3 months, then take a break for 1 month, before starting again.

5Patient Review

6/30/2009

Bontril for Overweight

Bontril has been effective for me in losing weight; however, it also makes me feel very irritable. I think this is because it's a stimulant and those typically increase anxiety. So far, the drug has helped with my weight loss goals despite these side effects.

5Patient Review

5/21/2010

Bontril for Overweight

I've lost twelve pounds in three weeks thanks to this medication, and I couldn't be happier.

5Patient Review

10/12/2009

Bontril for Overweight

I saw significant results within two months.

5Patient Review

11/2/2011

Bontril for Overweight

Bontril was extremely effective for me. I lost 20lbs each of the first two months, and then 10lbs in the third month when I took it every other day.

View All Reviews

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Patient Q&A Section about bontril

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does Bontril work for weight loss?

"Phendimetrazine is a drug that is used to help people lose weight by reducing their appetite. It is often used in conjunction with a doctor-approved diet and exercise program."

Answered by AI

Is Bontril still available?

"The Bontril Slow Release product has been discontinued and is no longer available in the United States. If the Food and Drug Administration has approved generic versions of this product, there may be generic equivalents available from other manufacturers."

Answered by AI

What does Bontril do?

"This medication is designed to be used alongside a doctor-approved weight loss plan that includes reducing calorie intake and exercising regularly. It works by suppressing appetite."

Answered by AI

What is the difference between Bontril and phentermine?

"Bontril PDM can help you lose weight, but it shouldn't be used for long periods of time and it isn't for everyone. Adipex-P is effective at lowering appetite and helping with weight loss. Available in generic form, which is more affordable. You only need to take it for a short period of time."

Answered by AI