Bepreve

Itching, Allergic Conjunctivitis (AC)
Treatment
3 FDA approvals
5 Active Studies for Bepreve

What is Bepreve

BepotastineThe Generic name of this drug
Treatment SummaryBepotastine is a medication used to treat allergic rhinitis and itching/rash. It works by blocking histamine, a chemical released by the body during an allergic reaction. Bepotastine was approved in Japan in 2000 and 2002, and is sold under the brand name Talion. It is available as an oral and eye drop solution, with the eye drop version being sold in the U.S. under the brand name Bepreve since 2009.
Bepreveis the brand name
image of different drug pills on a surface
Bepreve Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Bepreve
Bepotastine
2009
7

Approved as Treatment by the FDA

Bepotastine, otherwise called Bepreve, is approved by the FDA for 3 uses which include Pruritus and Allergic Conjunctivitis (AC) .
Pruritus
Allergic Conjunctivitis (AC)
Itching

Effectiveness

How Bepreve Affects PatientsBepotastine is a medication that blocks the effects of histamine, a chemical that affects your body's immune system. It is a type of drug called a mast cell stabilizer and helps reduce inflammation and eosinophil movement in the body. Bepotastine does not cause the same side effects as other medications, such as dry mouth or drowsiness. It takes about a quarter of an hour to start working, and lasts up to 24 hours.
How Bepreve works in the bodyBepotastine treats itchy eyes caused by allergies. It works by blocking histamine, which is released when an allergen is present, from triggering an allergic reaction. It also helps to stabilize the cells which release histamine, and prevent additional cells from coming to the site of the allergic reaction, thus reducing inflammation and irritation.

When to interrupt dosage

The suggested measure of Bepreve is contingent on the determined condition. The amount likewise fluctuates with the mode of delivery (e.g. Solution or Solution / drops - Ophthalmic) noted in the table underneath.
Condition
Dosage
Administration
Itching
, 15.0 mg/mL, 1.5 %
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic
Allergic Conjunctivitis (AC)
, 15.0 mg/mL, 1.5 %
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic

Warnings

Bepreve has one contraindication and ought not to be taken while experiencing any of the conditions in the following table.Bepreve Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Bepotastine may interact with Pulse Frequency
There are 20 known major drug interactions with Bepreve.
Common Bepreve Drug Interactions
Drug Name
Risk Level
Description
Pitolisant
Major
The therapeutic efficacy of Pitolisant can be decreased when used in combination with Bepotastine.
Aclidinium
Minor
Bepotastine may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Bepotastine may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Albutrepenonacog alfa
Minor
Bepotastine may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Almasilate
Minor
Bepotastine may decrease the excretion rate of Almasilate which could result in a higher serum level.
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Bepreve Novel Uses: Which Conditions Have a Clinical Trial Featuring Bepreve?

19 trials are presently being conducted to examine the potential of Bepreve to alleviate Itch symptoms.
Condition
Clinical Trials
Trial Phases
Allergic Conjunctivitis (AC)
2 Actively Recruiting
Phase 3
Itching
3 Actively Recruiting
Phase 2, Phase 3, Not Applicable

Bepreve Reviews: What are patients saying about Bepreve?

5Patient Review
3/21/2011
Bepreve for Allergic Conjunctivitis
This drop is the only thing that has worked for my crazy itchy eyes this weekend ! Get the big bottle as my insurance company was charging me the same for a bottle half the size. Hope this stuff works just as good as the allergy season rolls in !
5Patient Review
12/17/2012
Bepreve for Allergic Conjunctivitis
Though very costly, this medication is like magic for me. It immediately relieves my allergies and I don't need to take other medications as frequently.
5Patient Review
7/15/2011
Bepreve for Allergic Conjunctivitis
This stuff is really great! By 8 PM, my vision was significantly improved. I only wish it wasn't so expensive.
5Patient Review
9/5/2015
Bepreve for Allergic Conjunctivitis
Bepreve cleared up my eyes within a week and I had no side effects!
4.3Patient Review
10/24/2012
Bepreve for Allergic Conjunctivitis
My allergy doctor told me these were good, but he should have told me they were MAGIC. I have had terrible eye allergies the past 6 weeks with intense itching and burning pain. I used two other drops that did nothing. I have used this for 3 days and it's like I have a new set of eyeballs. No more itching, burning, or pain. I'm a fan. Even though the drops are outrageously priced, ask your doctor for samples and a coupon before you buy them--I got both of which really helped financially.
View All Reviews
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Patient Q&A Section about bepreve

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is bepreve used for?

"Bepreve is a medication used to treat itching associated with allergic conjunctivitis. It works by blocking histamine receptors."

Answered by AI

What are the side effects of Bepreve eye drops?

"Unusual or unpleasant taste in the mouth, headache, eye irritation, stuffy nose, and sore throat are all symptoms of allergies."

Answered by AI

How many times a day do you use Bepreve eye drops?

"For the ophthalmic dosage form (eye drops):

For itching of the eyes:

Adults, teenagers, and children 2 years of age and older—Use one drop in the affected eye two times a day.

Children younger than 2 years of age—Use and dose must be determined by your doctor."

Answered by AI

Can you buy bepreve over the counter?

"Bepotastine (Bepreve) is not available over the counter and requires a prescription. If you are looking for an over the counter option, you may want to try Pataday (olopatadine) or Zaditor (ketotifen) which work similarly."

Answered by AI

Clinical Trials for Bepreve

Have you considered Bepreve clinical trials? We made a collection of clinical trials featuring Bepreve, we think they might fit your search criteria.
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