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What is Abilify
AripiprazoleThe Generic name of this drug
Treatment SummaryAripiprazole is a medication used to treat mental health conditions like schizophrenia, bipolar disorder, major depression, irritability in people with autism, and Tourette's syndrome. It can be taken orally or given as an injection to treat agitation related to schizophrenia or bipolar mania. Aripiprazole works by stimulating dopamine and serotonin receptors while inhibiting alpha-adrenergic and serotonin receptors. This drug was approved by the FDA in 2002.
Abilifyis the brand name
Abilify Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Abilify
Aripiprazole
2002
454
Approved as Treatment by the FDA
Aripiprazole, also known as Abilify, is approved by the FDA for 1 uses such as Schizophrenia .Schizophrenia
Used to treat Schizophrenia in combination with Aripiprazole lauroxil
Effectiveness
How Abilify Affects PatientsAripiprazole binds strongly to various receptors in the brain, such as those for serotonin, dopamine, and adrenaline. It also has weaker effects on other receptors. It is not yet known exactly how this binding of aripiprazole to these receptors results in its clinical effects.
How Abilify works in the bodyAripiprazole works to treat psychosis by activating dopamine and serotonin receptors. It may also cause unwanted side effects by affecting other receptors, such as the adrenergic alpha1 receptor, which can cause low blood pressure when standing.
When to interrupt dosage
The recommended dosage of Abilify is contingent upon the diagnosed condition, including Agitation, Schizophrenia and Alzheimer's Disease. The quantity of dosage is dependent on the mode of delivery noted in the table below.Condition
Dosage
Administration
Acute Coryza
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution, Injection, solution - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, Injection - Intramuscular
Schizophrenia
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution, Injection, solution - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, Injection - Intramuscular
Autism Spectrum Disorder (ASD)
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution, Injection, solution - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, Injection - Intramuscular
Tourette's Disorder (TD)
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution, Injection, solution - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, Injection - Intramuscular
Irritability
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution, Injection, solution - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, Injection - Intramuscular
Agitation
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution, Injection, solution - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, Injection - Intramuscular
Schizophrenia
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution, Injection, solution - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, Injection - Intramuscular
Bipolar Disorder
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution, Injection, solution - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, Injection - Intramuscular
Bipolar Disorder
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution, Injection, solution - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, Injection - Intramuscular
Psychotic Depression
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution, Injection, solution - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, Injection - Intramuscular
Alzheimer's Disease
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution, Injection, solution - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, Injection - Intramuscular
Depression
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution, Injection, solution - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, Injection - Intramuscular
Bipolar Disorder
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
, Oral, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution, Injection, solution - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, Injection - Intramuscular
Warnings
Abilify ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Aripiprazole may interact with Pulse Frequency
Common Abilify Drug Interactions
Drug Name
Risk Level
Description
Acepromazine
Major
Aripiprazole may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Acepromazine.
Aclidinium
Major
The risk or severity of adverse effects can be increased when Aripiprazole is combined with Aclidinium.
Alfuzosin
Major
Aripiprazole may increase the hypotensive activities of Alfuzosin.
Amisulpride
Major
Aripiprazole may increase the antipsychotic activities of Amisulpride.
Aripiprazole lauroxil
Major
Aripiprazole may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole lauroxil.
Abilify Toxicity & Overdose RiskThere have been no studies done on the safety and effectiveness of taking aripiprazole while pregnant. However, a national pregnancy registry is tracking mothers who take it while pregnant. Studies of other antipsychotic medications during pregnancy have found that babies are at risk of developing symptoms like muscle stiffness or withdrawal. Animal studies of aripiprazole have linked it to birth defects and fetal death at higher doses than the recommended for humans. Aripiprazole should only be prescribed if the benefits outweigh the risks. Babies exposed to the drug in the third trimester may develop symptoms like muscle stiffness or withdrawal that can last from hours to
Abilify Novel Uses: Which Conditions Have a Clinical Trial Featuring Abilify?
Currently, 469 active clinical trials are underway to ascertain the potential of Abilify in treating Alzheimer's Disease, Early Infantile Autism and Irritability.Condition
Clinical Trials
Trial Phases
Schizophrenia
34 Actively Recruiting
Early Phase 1, Not Applicable, Phase 4
Bipolar Disorder
1 Actively Recruiting
Phase 4
Bipolar Disorder
0 Actively Recruiting
Agitation
5 Actively Recruiting
Phase 3, Phase 2
Bipolar Disorder
0 Actively Recruiting
Acute Coryza
1 Actively Recruiting
Not Applicable
Autism Spectrum Disorder (ASD)
55 Actively Recruiting
Phase 3, Not Applicable, Phase 2, Phase 4, Phase 1, Early Phase 1
Schizophrenia
174 Actively Recruiting
Not Applicable, Phase 3, Phase 2, Early Phase 1, Phase 4, Phase 1
Alzheimer's Disease
31 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 3
Depression
199 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Phase 4, Early Phase 1
Tourette's Disorder (TD)
2 Actively Recruiting
Not Applicable, Phase 3
Irritability
4 Actively Recruiting
Not Applicable, Phase 4
Psychotic Depression
0 Actively Recruiting
Abilify Reviews: What are patients saying about Abilify?
5Patient Review
6/18/2022 I've been on Trintellix for a few years now and, recently, I had been feeling very depressed and suicidal. However, my psychiatrist put me on Abilify and, after just three days, I'm virtually depression-free! This feels like a miracle to me; I haven't felt this good in years!
5Patient Review
6/30/2022 Abilify has worked very well for me over the last five years. It's important to remember that people react differently to medications, so what works for one person might not work for another.
4.7Patient Review
9/15/2022 This treatment has been working great for me. I have seen a significant reduction in my depression symptoms, which has had a positive impact on my quality of life. I have experienced some side effects, but they are manageable and haven't impacted my ability to live a normal life.
4.7Patient Review
9/9/2022 My kids think this is for schizophrenia. This is dangerous to translate because they are from broken homes and it's safe to say I am not any longer. It has several uses, but I use it for depression. Strong.
3.3Patient Review
11/6/2022 While this did an amazing job at stabilizing my mood, the side effects were just too much for me to handle. My anxiety increased significantly while taking this medication and made it hard to focus on anything else or go about my daily routine.
1Patient Review
7/22/2022 Do not under any circumstances take this drug. It completely ruined my life by causing me to gain an excessive amount of weight and develop a gambling addiction. The company who makes it, Bristol-Meyers, claims they did nothing wrong but I disagree.
1Patient Review
9/1/2022 ABILIFY is poison and caused me to become a compulsive gambler. It's completely useless and should be illegal. The company that manufactures it is scamming American taxpayers by making insurance companies pay outrageous prices for their drug.
1Patient Review
9/16/2022 As a child, I was prescribed this medication and it caused me to have uncontrollable muscle spasms in my jaw. My mouth was stuck shut and I came dangerously close to breaking my jaw. All the psychiatrist did was lower my dosage, but I was forced to take this for 2 years due to my age. Now, 18 years later, I suffer from chronic TMJ as a result of long-term side effects.
Patient Q&A Section about abilify
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the drug Abilify used for?
"Aripiprazole is a medication that can be used to treat mental disorders such as bipolar I disorder, major depressive disorder, and schizophrenia. It can be used by itself or in combination with other medications."
Answered by AI
What are the negative side effects of Abilify?
"The following side effects may occur: dizziness, lightheadedness, drowsiness, nausea, vomiting, tiredness, excess saliva/drooling, blurred vision, weight gain, constipation, headache, and trouble sleeping. If you experience any of these effects, tell your doctor or pharmacist."
Answered by AI
Is Abilify an antipsychotic or mood stabilizer?
"Abilify is an antipsychotic medication that affects chemicals in the brain to treat the symptoms of psychotic conditions like schizophrenia in adults and children aged 13 and up."
Answered by AI
Is Abilify an antipsychotic or antidepressant?
"The medicine Abilify is used to treat a variety of mental disorders, such as schizophrenia, bipolar disorder, Tourette syndrome, and irritability associated with autism. It can be used in combination with an antidepressant to treat depression."
Answered by AI