Zegerid

Zollinger-Ellison Syndrome, Curling Ulcer, Heartburn + 15 more

Treatment

15 FDA approvals

20 Active Studies for Zegerid

What is Zegerid

Omeprazole

The Generic name of this drug

Treatment Summary

Magnesium hydroxide is a naturally occurring mineral that is used in a variety of ways. It can be taken orally as a liquid suspension or chewable tablet to act as an antacid or laxative. It is also used commercially as a fire retardant due to its smoke suppressing and flame retardant properties. Magnesium hydroxide can also be applied directly to the skin to act as a deodorant or to treat canker sores.

Prilosec

is the brand name

image of different drug pills on a surface

Zegerid Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Prilosec

Omeprazole

1990

669

Approved as Treatment by the FDA

Omeprazole, otherwise called Prilosec, is approved by the FDA for 15 uses which include multiple endocrine adenomas and Gastro-esophageal Reflux Disease (GERD) .

multiple endocrine adenomas

Gastro-esophageal Reflux Disease (GERD)

Gastric Ulcer

Gastroesophageal Reflux

Healing

Zollinger-Ellison Syndrome

Helps manage Zollinger-Ellison Syndrome

Heartburn

Helps manage Heartburn

Stomach Ulcer

Duodenal Ulcer

Helicobacter Pylori Infection

Used to treat Helicobacter Pylori Infection in combination with Amoxicillin

Heartburn

Helps manage Heartburn

Heartburn

Erosive Esophagitis

Adenoma

Curling Ulcer

Effectiveness

How Zegerid Affects Patients

Magnesium hydroxide is an antacid, meaning it reduces stomach acid by reacting with hydrochloric acid in the stomach. This reaction forms magnesium chloride and water, which helps to reduce irritation in the stomach, raise the pH level, and stop pepsin from working. Magnesium hydroxide also strengthens the barrier between the stomach and esophagus, as well as improving the strength of the muscles that control the stomach and esophagus. As a laxative, magnesium hydroxide increases the amount of water in the intestines, causing the colon to expand and leading to increased movement in the digestive system and eventually evacuation of

How Zegerid works in the body

Magnesium hydroxide helps to neutralize stomach acid when taken in small doses. If taken in larger doses, it acts as a laxative. The magnesium hydroxide combines with stomach acid to form magnesium chloride and water, which helps to reduce stomach acidity. When taken in larger doses, it can draw water into the intestines, softening stools and increasing intestinal motility, which stimulates the urge to have a bowel movement. Magnesium hydroxide can also release a hormone called cholecystokinin, which helps the intestines absorb more water and electrolytes.

When to interrupt dosage

The degree of Zegerid is contingent upon the determined diagnosis, including Acid indigestion, Upset stomach and Antacid therapy. The quantity of dosage is dependent upon the mode of administration stated in the table below.

Condition

Dosage

Administration

Rheumatoid Arthritis

40.0 mg, , 10.0 mg, 20.0 mg, 20.6 mg, 2.5 mg

Oral, Capsule, delayed release pellets - Oral, , Capsule, delayed release pellets, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, delayed release - Oral, Tablet, delayed release, Capsule, Capsule - Oral, Kit, Powder, for suspension, Powder, for suspension - Oral, Granule, delayed release, Granule, delayed release - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Tablet, chewable, Tablet, chewable - Oral, Tablet - Oral, Tablet, Kit - Oral, For suspension - Oral, For suspension

Prophylaxis of NSAID gastric ulceration

40.0 mg, , 10.0 mg, 20.0 mg, 20.6 mg, 2.5 mg

Oral, Capsule, delayed release pellets - Oral, , Capsule, delayed release pellets, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, delayed release - Oral, Tablet, delayed release, Capsule, Capsule - Oral, Kit, Powder, for suspension, Powder, for suspension - Oral, Granule, delayed release, Granule, delayed release - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Tablet, chewable, Tablet, chewable - Oral, Tablet - Oral, Tablet, Kit - Oral, For suspension - Oral, For suspension

Heartburn

40.0 mg, , 10.0 mg, 20.0 mg, 20.6 mg, 2.5 mg

Oral, Capsule, delayed release pellets - Oral, , Capsule, delayed release pellets, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, delayed release - Oral, Tablet, delayed release, Capsule, Capsule - Oral, Kit, Powder, for suspension, Powder, for suspension - Oral, Granule, delayed release, Granule, delayed release - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Tablet, chewable, Tablet, chewable - Oral, Tablet - Oral, Tablet, Kit - Oral, For suspension - Oral, For suspension

Ankylosing Spondylitis

40.0 mg, , 10.0 mg, 20.0 mg, 20.6 mg, 2.5 mg

Oral, Capsule, delayed release pellets - Oral, , Capsule, delayed release pellets, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, delayed release - Oral, Tablet, delayed release, Capsule, Capsule - Oral, Kit, Powder, for suspension, Powder, for suspension - Oral, Granule, delayed release, Granule, delayed release - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Tablet, chewable, Tablet, chewable - Oral, Tablet - Oral, Tablet, Kit - Oral, For suspension - Oral, For suspension

hypersecretory conditions

40.0 mg, , 10.0 mg, 20.0 mg, 20.6 mg, 2.5 mg

Oral, Capsule, delayed release pellets - Oral, , Capsule, delayed release pellets, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, delayed release - Oral, Tablet, delayed release, Capsule, Capsule - Oral, Kit, Powder, for suspension, Powder, for suspension - Oral, Granule, delayed release, Granule, delayed release - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Tablet, chewable, Tablet, chewable - Oral, Tablet - Oral, Tablet, Kit - Oral, For suspension - Oral, For suspension

Gastroesophageal Reflux

40.0 mg, , 10.0 mg, 20.0 mg, 20.6 mg, 2.5 mg

Oral, Capsule, delayed release pellets - Oral, , Capsule, delayed release pellets, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, delayed release - Oral, Tablet, delayed release, Capsule, Capsule - Oral, Kit, Powder, for suspension, Powder, for suspension - Oral, Granule, delayed release, Granule, delayed release - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Tablet, chewable, Tablet, chewable - Oral, Tablet - Oral, Tablet, Kit - Oral, For suspension - Oral, For suspension

Heartburn

40.0 mg, , 10.0 mg, 20.0 mg, 20.6 mg, 2.5 mg

Oral, Capsule, delayed release pellets - Oral, , Capsule, delayed release pellets, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, delayed release - Oral, Tablet, delayed release, Capsule, Capsule - Oral, Kit, Powder, for suspension, Powder, for suspension - Oral, Granule, delayed release, Granule, delayed release - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Tablet, chewable, Tablet, chewable - Oral, Tablet - Oral, Tablet, Kit - Oral, For suspension - Oral, For suspension

Mastocytosis, Systemic

40.0 mg, , 10.0 mg, 20.0 mg, 20.6 mg, 2.5 mg

Oral, Capsule, delayed release pellets - Oral, , Capsule, delayed release pellets, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, delayed release - Oral, Tablet, delayed release, Capsule, Capsule - Oral, Kit, Powder, for suspension, Powder, for suspension - Oral, Granule, delayed release, Granule, delayed release - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Tablet, chewable, Tablet, chewable - Oral, Tablet - Oral, Tablet, Kit - Oral, For suspension - Oral, For suspension

Stomach Ulcer

40.0 mg, , 10.0 mg, 20.0 mg, 20.6 mg, 2.5 mg

Oral, Capsule, delayed release pellets - Oral, , Capsule, delayed release pellets, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, delayed release - Oral, Tablet, delayed release, Capsule, Capsule - Oral, Kit, Powder, for suspension, Powder, for suspension - Oral, Granule, delayed release, Granule, delayed release - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Tablet, chewable, Tablet, chewable - Oral, Tablet - Oral, Tablet, Kit - Oral, For suspension - Oral, For suspension

Helicobacter Pylori Infection

40.0 mg, , 10.0 mg, 20.0 mg, 20.6 mg, 2.5 mg

Oral, Capsule, delayed release pellets - Oral, , Capsule, delayed release pellets, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, delayed release - Oral, Tablet, delayed release, Capsule, Capsule - Oral, Kit, Powder, for suspension, Powder, for suspension - Oral, Granule, delayed release, Granule, delayed release - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Tablet, chewable, Tablet, chewable - Oral, Tablet - Oral, Tablet, Kit - Oral, For suspension - Oral, For suspension

Osteoarthritis

40.0 mg, , 10.0 mg, 20.0 mg, 20.6 mg, 2.5 mg

Oral, Capsule, delayed release pellets - Oral, , Capsule, delayed release pellets, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, delayed release - Oral, Tablet, delayed release, Capsule, Capsule - Oral, Kit, Powder, for suspension, Powder, for suspension - Oral, Granule, delayed release, Granule, delayed release - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Tablet, chewable, Tablet, chewable - Oral, Tablet - Oral, Tablet, Kit - Oral, For suspension - Oral, For suspension

Zollinger-Ellison Syndrome

40.0 mg, , 10.0 mg, 20.0 mg, 20.6 mg, 2.5 mg

Oral, Capsule, delayed release pellets - Oral, , Capsule, delayed release pellets, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, delayed release - Oral, Tablet, delayed release, Capsule, Capsule - Oral, Kit, Powder, for suspension, Powder, for suspension - Oral, Granule, delayed release, Granule, delayed release - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Tablet, chewable, Tablet, chewable - Oral, Tablet - Oral, Tablet, Kit - Oral, For suspension - Oral, For suspension

Curling Ulcer

40.0 mg, , 10.0 mg, 20.0 mg, 20.6 mg, 2.5 mg

Oral, Capsule, delayed release pellets - Oral, , Capsule, delayed release pellets, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, delayed release - Oral, Tablet, delayed release, Capsule, Capsule - Oral, Kit, Powder, for suspension, Powder, for suspension - Oral, Granule, delayed release, Granule, delayed release - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Tablet, chewable, Tablet, chewable - Oral, Tablet - Oral, Tablet, Kit - Oral, For suspension - Oral, For suspension

Adenoma

40.0 mg, , 10.0 mg, 20.0 mg, 20.6 mg, 2.5 mg

Oral, Capsule, delayed release pellets - Oral, , Capsule, delayed release pellets, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, delayed release - Oral, Tablet, delayed release, Capsule, Capsule - Oral, Kit, Powder, for suspension, Powder, for suspension - Oral, Granule, delayed release, Granule, delayed release - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Tablet, chewable, Tablet, chewable - Oral, Tablet - Oral, Tablet, Kit - Oral, For suspension - Oral, For suspension

Erosive Esophagitis

40.0 mg, , 10.0 mg, 20.0 mg, 20.6 mg, 2.5 mg

Oral, Capsule, delayed release pellets - Oral, , Capsule, delayed release pellets, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, delayed release - Oral, Tablet, delayed release, Capsule, Capsule - Oral, Kit, Powder, for suspension, Powder, for suspension - Oral, Granule, delayed release, Granule, delayed release - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Tablet, chewable, Tablet, chewable - Oral, Tablet - Oral, Tablet, Kit - Oral, For suspension - Oral, For suspension

Stomach Ulcer

40.0 mg, , 10.0 mg, 20.0 mg, 20.6 mg, 2.5 mg

Oral, Capsule, delayed release pellets - Oral, , Capsule, delayed release pellets, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, delayed release - Oral, Tablet, delayed release, Capsule, Capsule - Oral, Kit, Powder, for suspension, Powder, for suspension - Oral, Granule, delayed release, Granule, delayed release - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Tablet, chewable, Tablet, chewable - Oral, Tablet - Oral, Tablet, Kit - Oral, For suspension - Oral, For suspension

Healing

40.0 mg, , 10.0 mg, 20.0 mg, 20.6 mg, 2.5 mg

Oral, Capsule, delayed release pellets - Oral, , Capsule, delayed release pellets, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, delayed release - Oral, Tablet, delayed release, Capsule, Capsule - Oral, Kit, Powder, for suspension, Powder, for suspension - Oral, Granule, delayed release, Granule, delayed release - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Tablet, chewable, Tablet, chewable - Oral, Tablet - Oral, Tablet, Kit - Oral, For suspension - Oral, For suspension

Peptic Ulcer

40.0 mg, , 10.0 mg, 20.0 mg, 20.6 mg, 2.5 mg

Oral, Capsule, delayed release pellets - Oral, , Capsule, delayed release pellets, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, delayed release - Oral, Tablet, delayed release, Capsule, Capsule - Oral, Kit, Powder, for suspension, Powder, for suspension - Oral, Granule, delayed release, Granule, delayed release - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Delayed Release, Tablet, Delayed Release - Oral, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Tablet, chewable, Tablet, chewable - Oral, Tablet - Oral, Tablet, Kit - Oral, For suspension - Oral, For suspension

Warnings

Zegerid Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Omeprazole may interact with Pulse Frequency

Severe Hypersensitivity Reactions

Do Not Combine

Omeprazole may interact with Pulse Frequency

There are 20 known major drug interactions with Zegerid.

Common Zegerid Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Omeprazole.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be increased when combined with Omeprazole.

Alectinib

Major

The metabolism of Alectinib can be increased when combined with Omeprazole.

Aminophylline

Major

The metabolism of Aminophylline can be increased when combined with Omeprazole.

Amoxapine

Major

The metabolism of Amoxapine can be decreased when combined with Omeprazole.

Zegerid Toxicity & Overdose Risk

The toxic dose of magnesium hydroxide in rats is 8500mg/kg. Common side effects include drowsiness and feeling flushed. If taken daily, it can cause changes in fluid and electrolyte levels. Taking too much may cause abdominal cramping, nausea, and/or diarrhea. Symptoms of overdose include gastrointestinal irritation, watery diarrhea, nausea, vomiting, feeling flushed, thirst, low blood pressure, confusion, weak muscles, slowed breathing, irregular heartbeat, coma, and cardiac arrest. It should not be used if someone has kidney disease or a magnesium restricted diet, sudden changes in bowel movements lasting over two weeks, abdominal pain

image of a doctor in a lab doing drug, clinical research

Zegerid Novel Uses: Which Conditions Have a Clinical Trial Featuring Zegerid?

Presently, 43 active studies are assessing the potential of Zegerid to attenuate Gastric Acid Suppression, Flatulence and Acid Indigestion.

Condition

Clinical Trials

Trial Phases

Rheumatoid Arthritis

58 Actively Recruiting

Not Applicable, Phase 3, Phase 2, Phase 1, Phase 4

Heartburn

14 Actively Recruiting

Phase 3, Phase 2, Not Applicable, Phase 1

Gastroesophageal Reflux

0 Actively Recruiting

Prophylaxis of NSAID gastric ulceration

0 Actively Recruiting

Mastocytosis, Systemic

0 Actively Recruiting

hypersecretory conditions

0 Actively Recruiting

Stomach Ulcer

2 Actively Recruiting

Phase 4, Not Applicable

Erosive Esophagitis

2 Actively Recruiting

Phase 2, Phase 3

Helicobacter Pylori Infection

2 Actively Recruiting

Not Applicable, Phase 4

Ankylosing Spondylitis

2 Actively Recruiting

Phase 3, Not Applicable

Stomach Ulcer

0 Actively Recruiting

Heartburn

2 Actively Recruiting

Phase 3, Not Applicable

Zollinger-Ellison Syndrome

0 Actively Recruiting

Osteoarthritis

0 Actively Recruiting

Curling Ulcer

0 Actively Recruiting

Peptic Ulcer

0 Actively Recruiting

Adenoma

0 Actively Recruiting

Healing

0 Actively Recruiting

Zegerid Reviews: What are patients saying about Zegerid?

5

Patient Review

7/31/2012

Zegerid for Medication Treatment for Healing Erosive Esophagitis

I experienced some drowsiness while taking this medication, which was alleviated by running in the mornings. Otherwise, it did a great job at relieving my sensitive stomach and food allergies.

5

Patient Review

2/2/2012

Zegerid for Condition in which Stomach Acid is Pushed Into the Esophagus

This treatment has been extremely effective for me, though I have experienced some negative side effects like swollen ankles due to the high sodium content.

5

Patient Review

7/2/2011

Zegerid for Condition in which Stomach Acid is Pushed Into the Esophagus

My Gastro had me on every prescribe medication. Then He decided to try this. As I as well had surgery to try and control the acid reflux problem, which did help) But Zegerid in the powder form worked best for me. Some side effects but it is worth it. This is the FIRST time I have remarked on any medication.But again for what ever reason the pills where not effctive as well as the powder form for me. And it is instant relief within mins.

5

Patient Review

11/1/2011

Zegerid for Condition in which Stomach Acid is Pushed Into the Esophagus

This didn't work for me, unfortunately.

5

Patient Review

12/27/2011

Zegerid for Condition in which Stomach Acid is Pushed Into the Esophagus

This medication has done wonders for my son who suffers from GERD. He used to be in a lot of pain, and would even choke sometimes. Now he's practically symptom-free and it's made such a difference in his quality of life.

5

Patient Review

12/26/2013

Zegerid for Conditions of Excess Stomach Acid Secretion

I was struggling with GERDs and tried a bunch of different meds that didn't help at all. A friend recommended this one, and I'm so glad they did! It's by far the best medication I've tried—I don't even get breakthrough symptoms anymore.

5

Patient Review

7/25/2015

Zegerid for Condition in which Stomach Acid is Pushed Into the Esophagus

I cannot stress enough how much this has helped me. I was struggling with gastroparesis and GERD for years, and nothing the doctors gave me ever worked. But Zegerid? Zegerid is a life saver.

5

Patient Review

4/12/2014

Zegerid for Condition in which Stomach Acid is Pushed Into the Esophagus

This is the only medication that works for my GERD. No side effects to speak of. Slightly pricey...but so is an ER visit.

5

Patient Review

5/12/2016

Zegerid for Condition in which Stomach Acid is Pushed Into the Esophagus

I've been taking Zegrid for a long time to manage my stomach acid. I've tried other proton pump inhibitors, but I always come back to this one because it's the most effective.

5

Patient Review

11/28/2015

Zegerid for Condition in which Stomach Acid is Pushed Into the Esophagus

This treatment is really effective. I've tried other things like Prilosec, but this is by far the best.

4.7

Patient Review

5/24/2011

Zegerid for Condition in which Stomach Acid is Pushed Into the Esophagus

4.7

Patient Review

4/20/2012

Zegerid for Condition in which Stomach Acid is Pushed Into the Esophagus

Zegrid has been an absolute lifesaver for me. I can now eat and drink things that were previously off limits due to my acid reflux. It's amazing how much this medication has improved my quality of life.

3

Patient Review

9/23/2013

Zegerid for Conditions of Excess Stomach Acid Secretion

I'm really surprised at how quickly Zegerid worked.

2.7

Patient Review

8/24/2011

Zegerid for Condition in which Stomach Acid is Pushed Into the Esophagus

This provided some relief, which was good.

2.3

Patient Review

10/16/2011

Zegerid for Conditions of Excess Stomach Acid Secretion

After taking Zegrid for two days, I started feeling awful. I had fatigue, body aches, headaches, and nausea. So, I stopped taking it.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about zegerid

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the difference between Zegerid and Prilosec?

"Both Zegerid and Prilosec contain PPIs, but Zegerid also has an antacid. You can get Prilosec OTC or as a generic, and side effects for both drugs can include headache, stomach/abdominal pain, nausea, gas, and diarrhea."

Answered by AI

Which is better Nexium or Zegerid?

"Nexium works to relieve heartburn better than other antacids, but there are some risks associated with long-term use. Most people can take Zegerid without any noticeable side effects. Zegerid lasts longer than other types of antacids, so you may only need to take it once a day."

Answered by AI

What is Zegerid used for?

"Zegerid OTC is a heartburn medication that contains the proton pump inhibitor omeprazole. It is used to treat frequent heartburn, which is defined as heartburn occurring two or more days per week. Omeprazole works by reducing acid production, which relieves heartburn symptoms."

Answered by AI

Is Zegerid the same as Zantac?

"Zegerid and Zantac are both used to treat stomach problems, but they work in different ways. Zegerid is a combination of a proton-pump inhibitor (PPI) and an antacid, while Zantac is an H2 (histamine-2) receptor blocker. Both drugs can cause side effects such as headache, stomach or abdominal pain, nausea, and diarrhea."

Answered by AI

Clinical Trials for Zegerid

Have you considered Zegerid clinical trials?

We made a collection of clinical trials featuring Zegerid, we think they might fit your search criteria.
Go to Trials
Image of Sunnybrook Health Sciences Centre in Toronto, Canada.

Steroids for Rheumatoid Arthritis

18+
All Sexes
Toronto, Canada

People living with rheumatoid arthritis (RA) often experience flares-periods where their symptoms suddenly get worse. These flares can cause significant pain, make it harder to move and do daily activities, and lower overall quality of life. Doctors often treat flares with medications called glucocorticoids (GCs), which reduce inflammation. These medications can be taken by mouth (oral/PO) or given as a single injection into the muscle (intramuscular/IM). However, it's not clear which option works better from the patient's point of view-especially when it comes to relief of symptoms, improvements in function, and satisfaction with treatment. Most research so far has focused on how well the drugs control the disease, rather than how they impact the patient's overall experience. Research Questions: 1. Does a single GC injection work just as well as taking pills over a few weeks in improving symptoms reported by patients? 2. How do the two treatments compare in terms of symptom relief, ability to function, and patient satisfaction? 3. What do patients think and feel about using GCs to treat RA flares? What the Investigators Think: The investigators believe that a one-time GC injection is just as good as taking pills for a few weeks when it comes to managing RA flares. In fact, the injection might even be safer and preferred by patients. What the Investigators are Doing: The investigators will study 220 adults with RA who are currently having a flare (with at least 3 swollen and tender joints). These patients will be recruited from rheumatology clinics at the University of Toronto and must not have used GCs in the past month. They will be randomly assigned to receive either: A single injection (Methylprednisolone 120 mg), or Oral pills (Prednisone starting at 15 mg daily and tapering down over 3 weeks). The main thing the investigators will look at is how much better patients feel after 6 weeks, based on a questionnaire designed to measure RA flares. The investigators will also look at how well they function, how satisfied they are with the treatment, and whether they had any side effects. In addition, 20 patients (10 from each group) will be interviewed to understand their experiences and opinions about flare treatment in more detail. Why This Is Possible: The investigators have already surveyed University of Toronto rheumatologists who support the idea and provided input on study design. The investigators have also partnered with experts in research methods, national arthritis organizations, and patient groups to make sure the study is relevant and meaningful. Ethics approval has been obtained. Why It Matters: RA flares can have a major impact on people's lives. While current treatments help control inflammation, the investigators need to better understand how these treatments affect people from their own perspective. This study will shift the focus to what matters most to patients, helping doctors and patients choose the best treatment based not only on medical results but also on the patient's experience. This could lead to more effective and personalized care for people living with RA.

Phase 4
Waitlist Available

Sunnybrook Health Sciences Centre (+4 Sites)

Image of Weill Cornell Medical College in New York, United States.

Health Coaching for Rheumatoid Arthritis

18+
All Sexes
New York, NY

The goal of this clinical trial is to learn if peer coaching works to reduce levels of anxiety and/or depression in adults diagnosed with Rheumatoid Arthritis (RA). The main questions it aims to answer are: Do people with RA who complete the intervention with a peer coach have lower levels of anxiety and/or depression at 6 months from baseline? Do people with RA who complete the intervention with a peer coach have lower levels of anxiety and/or depression at 6 months compared to those in the control arm? Researchers will compare the peer coaching intervention to an active-control arm (where people without RA coach participants on general health and nutrition topics) to see if peer coaching works to reduce anxiety and/or depression. Participants will meet with a coach every week for 9 weeks and complete several surveys before, during and after the intervention

Recruiting
Has No Placebo

Weill Cornell Medical College

Iris Y Navarro-Millán, MD

Bristol-Myers Squibb

Image of Humana Healthcare Research, Inc. in Louisville, United States.

Academic Detailing for Rheumatoid Arthritis

Any Age
All Sexes
Louisville, KY

The goal of this trial is to learn if an interactive evidence-based educational outreach visits to clinicians who prescribe biologics change prescribing of biosimilar medications. The main questions it aims to answer are: 1. Do educational outreach visits lead to a higher number of prescriptions for biosimilar versions of adalimumab? 2. Do in-person or virtual visits work better? Researchers will compare clinicians offered the educational outreach visit to those who are not offered the visit to see if there is a difference in prescribing of biosimilar versions of adalimumab instead of the original brand-name version. Participants will be offered the chance to meet with a trained clinician who will provide educational information tailored to their knowledge and attitudes on the topic. They will also be provided an educational brochure and patient educational materials.

Waitlist Available
Has No Placebo

Humana Healthcare Research, Inc. (+1 Sites)

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Image of University of California, Irvine - UCI Medical Center in Orange, United States.

Sling-Fiber Preservation vs. Conventional POEM for Achalasia

18+
All Sexes
Orange, CA

Peroral endoscopic myotomy (POEM) is an effective, minimally invasive treatment for achalasia, offering excellent rates of symptom relief. However, a significant drawback is the high incidence of gastroesophageal reflux disease (GERD) following the procedure. One proposed technical modification, the selective preservation of the sling fibers during gastric myotomy (SFP-POEM), may reduce this risk without compromising efficacy as compared to a conventional POEM procedure, which includes myotomy of the sling fibers. In this study, adults with achalasia will be randomly assigned to receive one of the two POEM technical approaches. Researchers will monitor whether preserving sling fibers reduces the rates of reflux esophagitis (classified as Los Angeles Grade B or higher) on follow-up endoscopy. Participants will be followed for up to 1 year after the procedure.

Waitlist Available
Has No Placebo

University of California, Irvine - UCI Medical Center

Jason Samarasena, MD, MBA

Image of University of Minnesota Medical School, Division of Rheumatic and Autoimmune Diseases in Minneapolis, United States.

Ultrasound Therapy for Rheumatoid Arthritis

18+
All Sexes
Minneapolis, MN

The At-Home ULTRA Study will evaluate performance of the MINI system as indicated for the treatment of adults with active, moderate to severe rheumatoid arthritis who are inadequate responders or are intolerant to conventional synthetic disease-modifying anti-rheumatic drugs (csDMARDs), biologic DMARDs (bDMARDs), or targeted synthetic DMARDs (tsDMARDs). The non-invasive study device delivers ultrasound stimulation to the spleen to reduce inflammation. The study will enroll at least 60 participants at up to 8 sites. There will be three arms consisting of two active stimulation groups (treatment) and one non-active stimulation group (sham-control). After completing the double-blinded primary endpoint assessment period at Week 12, there will be a one-way crossover of control participants to active stimulation and an additional 12 week follow-up with all participants to evaluate long-term outcomes.

Recruiting
Drug

University of Minnesota Medical School, Division of Rheumatic and Autoimmune Diseases (+4 Sites)

Daniel Zachs

SecondWave Systems Inc.

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