Xhance

House dust allergy, Sneezing, Allergic Rhinitis + 22 more

Treatment

20 Active Studies for Xhance

What is Xhance

Fluticasone propionate

The Generic name of this drug

Treatment Summary

Fluticasone propionate is a steroid medication used to reduce inflammation. It comes in the form of inhalers, nasal sprays, and topical treatments for various inflammatory conditions. Fluticasone propionate was approved by the FDA in 1990.

Cutivate

is the brand name

image of different drug pills on a surface

Xhance Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Cutivate

Fluticasone propionate

1990

366

Effectiveness

How Xhance Affects Patients

Fluticasone propionate works by activating certain receptors in the body and reducing inflammation in the lungs of rats. When used as a topical product, it is also linked to narrowing of the blood vessels in the skin.

How Xhance works in the body

Fluticasone propionate is used to reduce inflammation in the lungs. It works by activating certain receptors and decreasing the number of eosinophils, a type of white blood cell involved in inflammation.

When to interrupt dosage

The suggested dosage of Xhance is contingent upon the diagnosed condition, for instance Sinusitis, Chronic Obstructive Pulmonary Disease (COPD) and Non-Allergic Rhinitis. The dosage amount varies, subject to the delivery technique (e.g. Spray, metered - Nasal or Respiratory (inhalation)) itemized in the following table.

Condition

Dosage

Administration

prophylaxis of Allergic rhinitis

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Bronchitis, Chronic

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Eosinophilic Esophagitis

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Allergy to Mold

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Sinusitis

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Nasal Congestion

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Nose

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Rhinitis

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

House dust allergy

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Emphysema

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Rhinorrhea

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Hay Fever

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Sinusitis

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Adrenal Cortex Hormones

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

moderate, severe Seasonal Allergic Rhinitis

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Asthma

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Chronic Obstructive Pulmonary Disease

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Allergy to Tree Pollen

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Rhinitis, Allergic

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Allergy to Animal Dander

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Warnings

Xhance Contraindications

Condition

Risk Level

Notes

Status Asthmaticus

Do Not Combine

Asthma

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Fluticasone Propionate may interact with Pulse Frequency

Severe Hypersensitivity Reactions

Do Not Combine

Fluticasone Propionate may interact with Pulse Frequency

Severe Hypersensitivity Reactions

Do Not Combine

Fluticasone Propionate may interact with Pulse Frequency

There are 20 known major drug interactions with Xhance.

Common Xhance Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Fluticasone propionate is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Fluticasone propionate is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abemaciclib

Major

The metabolism of Abemaciclib can be decreased when combined with Fluticasone propionate.

Abetimus

Major

The risk or severity of adverse effects can be increased when Fluticasone propionate is combined with Abetimus.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be decreased when combined with Fluticasone propionate.

Xhance Toxicity & Overdose Risk

Not enough research has been done to know the effects of fluticasone propionate on specific populations. Generally, it has not been linked to cancer, mutations, or chromosomal changes. However, it has been found to cause birth defects in rats when given by injection and may suppress growth in infants when given through breast milk. Elderly patients may be more sensitive to side effects, and those with liver disease should be monitored closely. There is no difference in how fluticasone propionate is cleared from the body based on gender or race.

Xhance Novel Uses: Which Conditions Have a Clinical Trial Featuring Xhance?

389 active clinical trials are currently underway to assess the potential of Xhance to alleviate Nasal Congestion, House Dust Mite Allergy and Atopic Dermatitis.

Condition

Clinical Trials

Trial Phases

Bronchitis, Chronic

0 Actively Recruiting

Asthma

92 Actively Recruiting

Phase 1, Phase 4, Early Phase 1, Phase 2, Not Applicable, Phase 3

Chronic Obstructive Pulmonary Disease

76 Actively Recruiting

Phase 3, Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 4

Sinusitis

0 Actively Recruiting

Adrenal Cortex Hormones

0 Actively Recruiting

Emphysema

4 Actively Recruiting

Phase 2, Not Applicable

Sinusitis

6 Actively Recruiting

Early Phase 1, Phase 2, Phase 3, Phase 1

House dust allergy

0 Actively Recruiting

Rhinitis, Allergic

0 Actively Recruiting

Allergy to Mold

0 Actively Recruiting

Allergy to Tree Pollen

0 Actively Recruiting

Allergic Rhinitis

0 Actively Recruiting

Nose

0 Actively Recruiting

Eosinophilic Esophagitis

0 Actively Recruiting

moderate, severe Seasonal Allergic Rhinitis

0 Actively Recruiting

Sneezing

0 Actively Recruiting

Hay Fever

0 Actively Recruiting

House Dust Mite Allergy

0 Actively Recruiting

Non-Allergic Rhinitis

0 Actively Recruiting

Atopic Dermatitis

10 Actively Recruiting

Phase 2, Phase 3, Phase 4

Xhance Reviews: What are patients saying about Xhance?

5

Patient Review

1/2/2019

Xhance for Presence of Polyps in the Nose

I've had to use Xhance for a while now, and it's been great. I don't have any allergy symptoms anymore and my sense of smell is back, which is amazing. I just hope that it continues to work well during Spring.

5

Patient Review

8/21/2019

Xhance for Presence of Polyps in the Nose

Xhance has completely changed my quality of life for the better. I can smell and breathe normally again, something I haven't been able to do in years.

5

Patient Review

4/22/2022

Xhance for Presence of Polyps in the Nose

XHANCE has been incredibly effective for me in combating polyps. I've had four surgeries due to this issue, and after the last one my doctor could see that they were already beginning to grow back. However, since I started using XHANCE they have not returned at all.

5

Patient Review

8/22/2022

Xhance for Presence of Polyps in the Nose

I had to use prednisone for my chronic sinusitis before I found XHANCE. Thankfully, this product has helped me become symptom-free as of March 2022. It's pricey, but worth it to me.

5

Patient Review

10/24/2021

Xhance for Presence of Polyps in the Nose

Though the side effects were annoying, this treatment was definitely worth it.

3.3

Patient Review

8/9/2019

Xhance for Presence of Polyps in the Nose

My ENT prescribed me Xhance, and while it's been minimally effective, I can't afford the $400 price tag each month. It's a shame that healthcare in America is so expensive.

2.3

Patient Review

5/18/2020

Xhance for Presence of Polyps in the Nose

I've been using Xhance for the past year, but in the last three months, the devices have stopped working properly. They leak and can't maintain pressure before releasing the spray.

1

Patient Review

5/23/2019

Xhance for Presence of Polyps in the Nose

Though Xhance did reduce the swelling in my sinuses, I got migraines both times I used it. So unfortunately, I won't be able to continue using this product.

1

Patient Review

6/16/2021

Xhance for Presence of Polyps in the Nose

Xhance was great when it cost $500. I bought two bottles because it worked so well for me. Once the price dropped, though, it stopped working entirely. I've used four bottles since then with no results; something must have changed in the recipe. It's disappointing because it was such a blessing at first.

1

Patient Review

11/12/2021

Xhance for Presence of Polyps in the Nose

The price for this generic drug is way too high. You're better off going to Costco or Sam's and getting the brand name fluticasone for under $4 a month. It's the same exact drug but XHANCE wants to charge almost $400 a month for it.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about xhance

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Xhance prescribed for?

"Xhance is a nose spray that is used to treat nasal polyps. It has a special delivery system that gets the medication to where your polyps are, but it can sometimes cause nose bleeds and irritation."

Answered by AI

Is Xhance a steroid?

"The prescription medication Xhance is a corticosteroid nasal spray indicated for the treatment of nasal polyps in adults 18 years of age or older."

Answered by AI

Is Xhance the same as Flonase?

"XHANCE has the same active ingredient as FLONASE®, but it is not the same product. FLONASE® has not been approved by the FDA for the treatment of nasal polyps, while XHANCE uses an Exhalation Delivery System to carry medicine high and deep into the nose."

Answered by AI

Is Xhance stronger than Flonase?

"The researchers found that the Xhance geometric least squares mean Cmax was higher than with Flonase at 400 micrograms (16.02 vs 11.66 pg/mL, respectively; geometric mean ratio [GMR], 137.42%). The researchers also found that the Xhance and Flonase had similar geometric least squares mean AUC0-∞ values (97.30 vs 99.61 pg · h/mL; GMR, 97.78%)."

Answered by AI

Clinical Trials for Xhance

Image of ALS Global in Irving, United States.

GX-03 for Eczema

18 - 70
All Sexes
Irving, TX

This is a randomized, double-blind, vehicle-controlled clinical study designed to evaluate the efficacy and safety of GX-03, a topically applied emollient, in adult subjects with moderate to severe eczema. Approximately 120 adult participants will be enrolled and randomized in a 1:1 ratio to receive either GX-03 or a petrolatum-based vehicle control for 8 consecutive weeks. Efficacy will be assessed using validated clinical outcome measures, including the Eczema Area and Severity Index (EASI), the Validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD™), and the Peak Pruritus Numeric Rating Scale (PP-NRS). Safety will be evaluated through monitoring of treatment-emergent adverse events throughout the study period.

Phase 2
Recruiting

ALS Global

Turn Therapeutics

Image of Seeding Labs INC in Austin, United States.

Tailored Recommendations for Infant Gut Microbiome

No minimum age - 3
All Sexes
Austin, TX

The goal of this clinical trial is to learn whether microbiome analysis, education, and personalized recommendations can improve gut health and reduce early markers of immune-related conditions in infants aged 0-3 months delivered via Cesarean section. The study aims to determine whether these interventions can increase beneficial bacteria, decrease C-section-associated microbiome signatures, reduce opportunistic pathogens, and improve functional potential for HMO digestion and SCFA production. The study also seeks to assess whether improvements in microbiome composition are associated with a reduced prevalence of early atopic symptoms. Researchers will compare three groups: a full intervention arm that receives microbiome reports, coaching, personalized recommendations, and educational materials; a limited intervention arm that receives simplified reports and basic recommendations; and a control arm that receives no results until study completion. This design allows evaluation of both a comprehensive intervention and a more scalable, minimal-results model. Participants will: 1. Provide six microbiome stool samples over a 24-month period. 2. Provide additional small stool samples at two timepoints for exploratory metabolomic analysis. 3. Receive microbiome reports and guidance according to their assigned study arm. 4. Complete surveys on infant health history, symptoms, diet, and environmental exposures. 5. Participate in standardized eczema assessment(s) administered by a Nurse Practitioner and evaluated by a Pediatric Allergy Specialist if any symptoms are reported. This study seeks to demonstrate that targeted microbiome support can positively shift gut microbial development in C-section infants and may reduce risks linked to the early stages of the atopic march. Findings may inform scalable strategies for delivering microbiome-based support in early life and improve long-term health outcomes for this high-risk population.

Waitlist Available
Has No Placebo

Seeding Labs INC

Qian Yuan, MD

Seeding, Inc DBA Tiny Health

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We made a collection of clinical trials featuring Xhance, we think they might fit your search criteria.
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Image of Stanford University in Stanford, United States.

MoblO2 for Chronic Lung Diseases

18+
All Sexes
Stanford, CA

Many patients with chronic lung disease (e.g., chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD)) require supplemental oxygen (O2) at some point during their disease course. Practitioners prescribe O2 to patients with chronic lung disease in hopes of the following: 1) that it will limit desaturation events and combat breathlessness, thus preventing the frustratingly slow pace and numerous rest breaks patients are forced to adopt while doing even simple tasks; 2) that it will allow patients to be more active physically (perhaps increase their ability to exercise) and socially (perhaps leave the home more often); 3) that it will stave off putative complications of hypoxemia (e.g., cognitive dysfunction, pulmonary hypertension) and 4) that it will improve health-related quality of life (HRQL). However, despite the rationale for O2, and prescribers' good intentions, patients generally view O2 with frustration and fear - it threatens their HRQL, which is already impaired by having a condition that imposes itself on every aspect of their lives. Nasal cannulas and delivery devices call unwanted attention to patients when they are out in public. O2 users feel stigmatized and are often viewed as "smokers who get what they deserve, even if they never smoked a day in their lives" - or as disabled, sick or even infectious. O2 steals patients' independence, forcing them to plan their lives around it. The anxiety that patients and their caregivers experience around running out of oxygen, or not getting enough, immobilizes them and restricts participation in activities outside of the home. O2 disrupts the home environment, adding stress, and creating a burden for patients' caregiver-loved-ones who are often saddled with the responsibility of ensuring adequate equipment and supply of O2, and O2 is a constant reminder to patients they are living with a condition that could shorten their lives. O2 delivery equipment is typically heavy, unwieldy and intimidating. Different recommendations (e.g., insurance companies use 88% as a cut-off for SpO2, while many practitioners focus on 90%) make it confusing for patients, which almost certainly affects adherence. O2-requiringpatients are starving for things that can make their lives easier. An auto-adjusting O2 delivery device - one that automatically delivers the correct amount of O2 to maintain blood oxygen at desired, pre-set levels - would alleviate the need for patients to constantly (incessantly for many) monitor their peripheral oxygen saturation (SpO2) and adjust O2flow to meet the demands as exertion levels vary . The MoblO2 device is a battery-operated, light-weight, closed-loop O2 delivery device that houses a regulator (which attaches to compressed gas O2 tanks) and adjusts O2 flow to meet a pre-set blood oxygen level. A pulse oximeter is worn on the ear and transmits via Bluetooth to the device, which adjusts an internal valve to control flow on a second-to-second basis. The user sets the dial to the highest flow of O2 needed to meet the demands of activities they might perform (up to 15 liters per minute), and the device adjusts flow, up to the pre-set level to maintain SpO2 at a preset level (e.g., \> 90%). To conserve O2 supply in the tank - and to avoid over-oxygenation (which could be problematic for a small percentage of patients with the most severe COPD) - the MoblO2 begins to limit O2 flow at a SpO2 of 93%. The device can be manually over-ridden by the user, and should the battery run out - or the device fail for some unforeseen reason - the default position is valve open, so the users receive whatever flow of oxygen has been set on the dial. Given the substantial burdens of O2 on patients and their families, the hassles patients describe with having to monitor their SpO2 and repeatedly adjust the flow of O2 to meet their needs, patients and experts around the world have called for improvements in O2 delivery equipment. The MoblO2 is just such a remarkable improvement and a giant step forward in helping to ease the burdens of O2 on patients who require it. The purpose of this study is to investigate the effects of the MoblO2 O2 delivery device on a range of outcomes, including physical activity, amount (liters) O2 use; maintenance of adequate SpO2 levels; patient reported outcomes including symptoms, HRQL and satisfaction with the MoblO2 O2 device.

Waitlist Available
Has No Placebo

Stanford University

Jeff Swigris, DO, MS

Minnesota Health Solutions

Have you considered Xhance clinical trials?

We made a collection of clinical trials featuring Xhance, we think they might fit your search criteria.
Go to Trials

Have you considered Xhance clinical trials?

We made a collection of clinical trials featuring Xhance, we think they might fit your search criteria.
Go to Trials