Radiation therapy - 3 weeks for Breast Cancer

Phase-Based Progress Estimates
2
Effectiveness
3
Safety
Breast CancerRadiation therapy - 3 weeks - Radiation
Eligibility
19 - 90
Female
What conditions do you have?
Select

Study Summary

This trial is testing whether a shorter, more intensive course of radiation therapy is as effective as the standard course of treatment for early stage breast cancer.

Treatment Effectiveness

Effectiveness Progress

2 of 3
This is further along than 85% of similar trials

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: 5 years

5 years
Number of participants who demonstrate local control at 5 year follow up
up to 5 years
Number of patients with adverse events receiving radiation therapy between the two arms Arm 1 (15 fractions) and Arm 2 (10 fractions).

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Trial Design

2 Treatment Groups

ARM 1-4050cGY and boost to tumor bed of 4800cGY in 15fractions
1 of 2
ARM 2 - 3200cGY and boost to tumor bed of 4200cGY -10fractions
1 of 2

Experimental Treatment

400 Total Participants · 2 Treatment Groups

Primary Treatment: Radiation therapy - 3 weeks · No Placebo Group · Phase 3

ARM 1-4050cGY and boost to tumor bed of 4800cGY in 15fractions
Radiation
Experimental Group · 1 Intervention: Radiation therapy - 3 weeks · Intervention Types: Radiation
ARM 2 - 3200cGY and boost to tumor bed of 4200cGY -10fractions
Radiation
Experimental Group · 1 Intervention: Radiation therapy - 2 weeks · Intervention Types: Radiation

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 5 years

Who is running the clinical trial?

Weill Medical College of Cornell UniversityLead Sponsor
989 Previous Clinical Trials
1,338,530 Total Patients Enrolled
25 Trials studying Breast Cancer
39,805 Patients Enrolled for Breast Cancer
Silvia Formenti, M.D.Principal InvestigatorWeill Medical College of Cornell University
10 Previous Clinical Trials
822 Total Patients Enrolled
5 Trials studying Breast Cancer
342 Patients Enrolled for Breast Cancer

Eligibility Criteria

Age 19 - 90 · Female Participants · 5 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
Breast cancer with negative margins.
Breast cancer with bilateral tumors, pT1-2, and negative margins.
You have pT1-2 breast cancer.