Study Summary
This trial will study the safety and effectiveness of simufilam, a drug for Alzheimer's disease, for one year. 750 people with mild-to-moderate Alzheimer's will be given the drug or a placebo twice daily. The trial will assess cognitive enhancement and functional decline.
Video Summary
Treatment Effectiveness
Effectiveness Progress
Study Objectives
2 Primary · 7 Secondary · Reporting Duration: Baseline (Study Day 1) to Week 52
Trial Safety
Safety Progress
Trial Design
2 Treatment Groups
Simufilam 100 mg
1 of 2
Placebo
1 of 2
Experimental Treatment
Non-Treatment Group
750 Total Participants · 2 Treatment Groups
Primary Treatment: Simufilam · Has Placebo Group · Phase 3
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18+ · All Participants · 9 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:About The Reviewer
Michael Gill - B. Sc.
First Published: October 30th, 2021
Last Reviewed: November 27th, 2022
Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.
Who else is applying?
What state do they live in?
| California | 28.6% |
| Ohio | 14.3% |
| Indiana | 14.3% |
| Other | 42.9% |
How old are they?
| 18 - 65 | 80.0% |
| 65+ | 20.0% |
What site did they apply to?
| Advanced Research Center, Inc | 50.0% |
| Sun Valley Research Center, Inc. | 25.0% |
| MD Clinical - Velocity Clinical Research | 25.0% |
What portion of applicants met pre-screening criteria?
| Met criteria | 83.3% |
| Did not meet criteria | 16.7% |
How responsive is this trial?
Most responsive sites:
- Sun Valley Research Center, Inc.: < 48 hours
- Advanced Research Center, Inc: < 48 hours
Average response time
- < 2 Days
Typically responds via
| 50.0% | |
| Phone Call | 50.0% |