Weight loss treatment for Overeating

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Drexel University, Philadelphia, PA
Overeating+6 More
Weight loss treatment - Behavioral
Eligibility
< 65
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether a decision-making intervention can help adolescents lose weight.

See full description

Eligible Conditions

  • Overeating
  • Impulsive Behavior
  • Overweight or Obesity
  • Overweight Adolescents

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Weight loss treatment will improve 1 primary outcome in patients with Overeating. Measurement will happen over the course of 16 weeks.

16 weeks
Percent of 95 percentile BMI

Trial Safety

Safety Estimate

1 of 3

Trial Design

1 Treatment Group

Adolescent-specific behavioral weight loss treatment
1 of 1
Experimental Treatment

This trial requires 80 total participants across 1 different treatment group

This trial involves a single treatment. Weight Loss Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Adolescent-specific behavioral weight loss treatment
Behavioral
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Weight loss treatment
2007
Completed Phase 4
~260

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 16 weeks
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 16 weeks for reporting.

Closest Location

Drexel University - Philadelphia, PA

Eligibility Criteria

This trial is for patients born any sex aged 65 and younger. There are 7 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Have a smartphone, are willing to download an app to track food intake and complete surveys on the phone for two seven-day periods throughout the course of the study, and are willing to wear a fitness tracker during these same two week-long periods
Are between 14 and 18 years of age
Have a BMI between the 85th and 99th percentiles for sex and age as determined by the CDC growth charts
Are currently living at home with a parent or guardian
Have at least one parent or guardian who is willing to participate in the study
Are willing to complete baseline assessment tasks
Are located in the US and wiling/able to participate in remote intervention and assessments

Patient Q&A Section

What are common treatments for overweight?

"There is significant evidence to support weight management through exercise and nutrition counseling. In the U.S., obese children typically lose about 15%-30% of excess weight as they mature; with this weight loss being maintained for up to 3-5 years. Exercise, however, has been found to be the most effective way to help combat excessive weight gain. Physical activity can not only reduce body fat, but also alleviate the negative effects of obesity. As a result, it is the recommended method to lose and maintain weight. There is moderate to good evidence that physical activity can help prevent certain diseases like heart disease and osteoporosis, and will make overweight people feel much better, even when only weight loss is desired." - Anonymous Online Contributor

Unverified Answer

Can overweight be cured?

"Overweight can be cured in very many cases. Not only, however, the cause of this illness but all life circumstances, particularly the way one lives the rest of life, can be modified. Obesity is not simply an external problem of the individual at work. In addition to lifestyle changes, proper diet and exercise are the key to success in the fight to lose weight." - Anonymous Online Contributor

Unverified Answer

What are the signs of overweight?

"Women with higher adiposity tended to have higher plasma triglyceride to high-density lipoprotein cholesterols. Higher waist-to-height ratio was also associated with higher triglyceride/high-density lipoprotein cholesterol and waist-to-height ratio was associated with higher low-density lipoprotein cholesterol. In boys, higher fat mass was correlated with higher triglyceride/high-density lipoprotein cholesterol and lower fasting plasma glucose. Higher total to high-density lipoprotein cholesterol was related to higher total cholesterol and lower low-density lipoprotein cholesterol. This information will be valuable in identifying those at risk for obesity and pre-diabetes." - Anonymous Online Contributor

Unverified Answer

What causes overweight?

"This is one of the few topics where you can make one major break. When we start studying the causes of an unhealthy weight we stop thinking about causes. We just consider how we can prevent a person from going to this unhealthy place when they begin losing weight, this should be our main area of study, we also have not even begun to look into why and how unhealthy it seems for their bodies to go to this state of being overweight." - Anonymous Online Contributor

Unverified Answer

What is overweight?

"Obese children in Saudi Arabia are similar to Americans. It is well known that in the Saudi community, children and adolescents with overweight are more likely to be overweight and to become obese." - Anonymous Online Contributor

Unverified Answer

How many people get overweight a year in the United States?

"Approximately 21.7 million Americans are overweight, with 8% of men being categorized as obese and 1/3 women being categorized as overweight. For women, nearly 1 in every 5 women aged 65-74 was classified as overweight in the last year, compared with 1 in every 4 among men of the same age range. The rising rate of obesity and the subsequent excesses of obesity such as high blood pressure and diabetes, as well as increased morbidity, have led to considerable attention given to the role of prevention and treatment of obesity for improving health. Over the last few years, the number of people with elevated blood pressure has been increasing by 7% per year, as well as the number of Americans who are obese by 2%." - Anonymous Online Contributor

Unverified Answer

Who should consider clinical trials for overweight?

"Clinical trials are generally only available for patients with a body mass index (BMI) ≥ 30 kg/m2 or a BMI ≥ 35 kg/m2 for bariatric surgery trials. To offer these trials to patients in this range, rigorous clinical evaluation of the safety and efficacy of these treatments is necessary. The need for studies to assess the long-term safety for obese patients receiving bariatric surgery alone or in combination with pharmacotherapy is great and warrants consideration of this subgroup of patients." - Anonymous Online Contributor

Unverified Answer

What is the primary cause of overweight?

"We conclude that there appears to be a strong genetic influence for overweight and obesity, particularly the susceptibility of a predisposition on family history of diabetes mellitus type 2." - Anonymous Online Contributor

Unverified Answer

What is the latest research for overweight?

"Obesity can be associated with various co-morbidities including hypertension, diabetes mellitus, and cardiovascular diseases in both men and women. The presence of cardiovascular health problems, even in the low BMI range, may be more common in women than in men. Future studies need to be conducted to further investigate this topic." - Anonymous Online Contributor

Unverified Answer

What is the average age someone gets overweight?

"There is little age information for the overweight population in Canada compared to the United States. However, the weight in Canada is mostly of a younger population. This can be a problem for the health care system because the overweight population has more medical issues. The medical system will have to do more with this population to help them gain weight in a healthier way and therefore gain weight at a lower risk for all the complications of obesity like cardiovascular disease (heart attacks and stroke) and certain cancers (breast, colon and endometrial cancers)." - Anonymous Online Contributor

Unverified Answer

Has weight loss treatment proven to be more effective than a placebo?

"Weight loss treatment has not been proven to decrease or control the rate or intensity of future weight gain. However, a placebo-controlled study would provide further information." - Anonymous Online Contributor

Unverified Answer

How does weight loss treatment work?

"The findings of the present investigation provide new insights into the effect of obesity weight loss treatment. The findings are consistent with the proposition that an improved sense of well-being occurs following weight loss treatment. Additionally, results suggest that a better sense of well-being may enhance weight-loss efficacy but it is not the only mechanism involved in weight loss. Other possibilities that need to be considered are changes in body image perception and self-efficacy." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
See if you qualify for this trial
Get access to this novel treatment for Overeating by sharing your contact details with the study coordinator.