Your session is about to expire
What is Ultram
TramadolThe Generic name of this drug
Treatment SummaryTramadol is a medication used to treat moderate to severe pain. It works differently than other opioid pain medications because it affects two types of neurotransmitters, serotonin and norepinephrine. This dual-action makes tramadol more effective at reducing pain from a variety of sources such as neuropathic pain, post-operative pain, lower back pain, labor pain, and cancer-related pain. It can also help with anxiety, depression, and shivering. Tramadol does carry a risk of side effects, including tolerance, dependence, abuse, and overdose. It can also cause seizures and serotonin syndrome if taken with
Ultramis the brand name
Ultram Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Ultram
Tramadol
1995
475
Approved as Treatment by the FDA
Tramadol, otherwise called Ultram, is approved by the FDA for 2 uses including Pain, Acute and Acute Pain .Pain, Acute
Used to treat Pain, Acute in combination with Acetaminophen
Acute Pain
Used to treat Pain, Acute in combination with Acetaminophen
Effectiveness
How Ultram Affects PatientsTramadol is a pain reliever that works by binding to opioid receptors in the central nervous system. It can help reduce pain and fever, but can also lead to dizziness, drowsiness, nausea, constipation, sweating, and itching. It does not cause histamine release like morphine, has no effect on heart rate or left-ventricular function, and can cause respiratory depression and suppress coughing. Seizures have been reported with tramadol, especially when taken in high doses. It also carries a risk of serotonin syndrome when taken with other drugs that affect serotonin levels. Gastrointestinal effects of taking
How Ultram works in the bodyTramadol is a medicine that works on the brain to control pain. It has a weak connection to opioid receptors, and it also helps to increase the amount of serotonin and norepinephrine in the brain. It is made up of two parts that work together to provide pain relief. One part binds to opioid receptors, while the other part helps keep serotonin and norepinephrine in the brain. Tramadol also affects a number of other pain modulators, including alpha2-adrenoreceptors, neurokinin 1 receptors, voltage-gated sodium channels, transient receptor potential cation channels, muscar
When to interrupt dosage
The recommended measure of Ultram is contingent upon the diagnosed affliction, including Pain, Pain and Acute Pain. The amount of dosage may differ as per the prescribed method of delivery (e.g. Capsule or Tablet) stated in the table below.Condition
Dosage
Administration
Pain
, 50.0 mg, 200.0 mg, 300.0 mg, 100.0 mg, 37.5 mg, 150.0 mg, 0.5 mg, 5.0 mg/mg, 400.0 mg, 75.0 mg, 1.0 mg/mL, 1.0 mg/mg, 5.8 mg/mg, 5.0 mg/mL, 44.0 mg
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Kit - Oral, Capsule, coated, extended release - Oral, Capsule, coated, extended release, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Topical, Cream - Topical, Cream, Tablet, delayed release, Tablet, delayed release - Oral, Solution, Solution - Oral
Pain
, 50.0 mg, 200.0 mg, 300.0 mg, 100.0 mg, 37.5 mg, 150.0 mg, 0.5 mg, 5.0 mg/mg, 400.0 mg, 75.0 mg, 1.0 mg/mL, 1.0 mg/mg, 5.8 mg/mg, 5.0 mg/mL, 44.0 mg
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Kit - Oral, Capsule, coated, extended release - Oral, Capsule, coated, extended release, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Topical, Cream - Topical, Cream, Tablet, delayed release, Tablet, delayed release - Oral, Solution, Solution - Oral
Pain
, 50.0 mg, 200.0 mg, 300.0 mg, 100.0 mg, 37.5 mg, 150.0 mg, 0.5 mg, 5.0 mg/mg, 400.0 mg, 75.0 mg, 1.0 mg/mL, 1.0 mg/mg, 5.8 mg/mg, 5.0 mg/mL, 44.0 mg
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Kit - Oral, Capsule, coated, extended release - Oral, Capsule, coated, extended release, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Topical, Cream - Topical, Cream, Tablet, delayed release, Tablet, delayed release - Oral, Solution, Solution - Oral
Premature Ejaculation
, 50.0 mg, 200.0 mg, 300.0 mg, 100.0 mg, 37.5 mg, 150.0 mg, 0.5 mg, 5.0 mg/mg, 400.0 mg, 75.0 mg, 1.0 mg/mL, 1.0 mg/mg, 5.8 mg/mg, 5.0 mg/mL, 44.0 mg
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Kit - Oral, Capsule, coated, extended release - Oral, Capsule, coated, extended release, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Topical, Cream - Topical, Cream, Tablet, delayed release, Tablet, delayed release - Oral, Solution, Solution - Oral
Acute Pain
, 50.0 mg, 200.0 mg, 300.0 mg, 100.0 mg, 37.5 mg, 150.0 mg, 0.5 mg, 5.0 mg/mg, 400.0 mg, 75.0 mg, 1.0 mg/mL, 1.0 mg/mg, 5.8 mg/mg, 5.0 mg/mL, 44.0 mg
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Kit - Oral, Capsule, coated, extended release - Oral, Capsule, coated, extended release, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Topical, Cream - Topical, Cream, Tablet, delayed release, Tablet, delayed release - Oral, Solution, Solution - Oral
Warnings
Ultram has eighteen contraindications, thus it should not be ingested when confronted with any of the conditions provided in the following table.Ultram ContraindicationsCondition
Risk Level
Notes
Mental Depression
Do Not Combine
Asthma
Do Not Combine
Abdomen
Do Not Combine
Alcohol Withdrawal Delirium
Do Not Combine
ethanol
Do Not Combine
Ileus
Do Not Combine
Pulmonary Heart Disease
Do Not Combine
Head
Do Not Combine
Pulse Frequency
Do Not Combine
Pulmonary Disease, Chronic Obstructive
Do Not Combine
Intoxication
Do Not Combine
Epilepsy
Do Not Combine
Severe Hepatic Impairment
Do Not Combine
Respiratory Insufficiency
Do Not Combine
Status Asthmaticus
Do Not Combine
Intestinal Obstruction
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Tramadol may interact with Pulse Frequency
Common Ultram Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Major
The risk or severity of adverse effects can be increased when Tramadol is combined with Aclidinium.
Azelastine
Major
Tramadol may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Carbamazepine
Major
The therapeutic efficacy of Carbamazepine can be decreased when used in combination with Tramadol.
Cimetropium
Major
The risk or severity of adverse effects can be increased when Tramadol is combined with Cimetropium.
Eluxadoline
Major
The risk or severity of constipation can be increased when Tramadol is combined with Eluxadoline.
Ultram Toxicity & Overdose RiskThe lowest toxic dose of tramadol in mice is 350mg/kg. Animal studies have not been able to confirm that tramadol causes cancer in humans, but there have been reports of it causing harm to embryos and fetuses. Additionally, there is no evidence to suggest that tramadol has an effect on fertility or can cause mutations.
Ultram Novel Uses: Which Conditions Have a Clinical Trial Featuring Ultram?
18 active trials are currently being conducted to assess the efficacy of Ultram in relieving Acute Pain, Chronic Pain and Pain.Condition
Clinical Trials
Trial Phases
Acute Pain
2 Actively Recruiting
Early Phase 1, Not Applicable
Pain
0 Actively Recruiting
Premature Ejaculation
0 Actively Recruiting
Pain
0 Actively Recruiting
Pain
0 Actively Recruiting
Ultram Reviews: What are patients saying about Ultram?
5Patient Review
5/15/2022 I have a lot of nerve pain and arthritis throughout my body. I've tried other treatments like injections and medication, but nothing works as well as tramadol. It's been a lifesaver for me since 2018.
5Patient Review
5/15/2022 I have a lot of nerve and arthritis pain throughout my body. I've tried injections, medication, and other treatments but nothing has worked as well as Tramadol. It stops the pain immediately for me.
5Patient Review
5/3/2022 I lifted something the wrong way and ended up with severe back pain and spasms. Tramadol worked like magic for me and completely relieved the pain.
5Patient Review
5/3/2022 I was in so much pain after I lifted something heavy and threw out my back. Spasms were constant. But as soon as I took tramadol, the pain completely disappeared. It's like magic!
4.3Patient Review
2/27/2022 I've been struggling with chronic back pain and sciatica for over two decades now. Previous treatments like Vicodin just left me feeling drowsy and unproductive at work. Tramadol really helps take the edge off so that I can still function normally despite the pain.
Patient Q&A Section about ultram
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the medicine Ultram used for?
"This medication is used to relieve moderate to moderately severe pain using Tramadol, an opioid analgesic. The drug works by changing how pain is felt and responded to in the brain."
Answered by AI
Why is Ultram an opioid?
"The medication ULTRAM contains the active ingredient tramadol, which is a type of drug that activates certain opioid receptors in the brain while also inhibiting the re-uptake of serotonin and norepinephrine. While the exact way that this drug works is not fully understood, it is believed that the pain-relieving effects of tramadol are due to both the activation of the µ-opioid receptors and the weak inhibition of serotonin and norepinephrine."
Answered by AI
Which is stronger oxycodone or Ultram?
"Tramadol may be less likely to cause addiction and dependence than oxycodone, but it is not as effective at relieving pain. Tramadol can cause mood-boosting properties and respiratory depression, but it also carries the risk of seizure."
Answered by AI
Is Ultram a strong medication?
"Tramadol (Ultram) is a potent painkiller that is used to relieve moderate to severe pain. It is typically used when non-opioid painkillers are no longer effective at controlling the pain."
Answered by AI
Clinical Trials for Ultram
Other Trials to Consider
Popular Categories
Learn More About These Treatments
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.