Tuzistra Xr

Catarrh, Chronic Pain, Acute Bronchitis + 10 more

Treatment

6 FDA approvals

20 Active Studies for Tuzistra Xr

What is Tuzistra Xr

Codeine

The Generic name of this drug

Treatment Summary

Diphenhydramine is an antihistamine drug used to treat allergies, hay fever, rhinitis, hives, and asthma. It is one of the most commonly used antihistamines and usually causes less drowsiness and sedation than other similar medications. Diphenhydramine is used in both humans and animals.

Soma

is the brand name

Tuzistra Xr Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Soma

Codeine

1960

398

Approved as Treatment by the FDA

Codeine, also known as Soma, is approved by the FDA for 6 uses like Pain and Pain .

Pain

Used in combination with Acetaminophen / Codeine for moderate Pain

Pain

Used in combination with Acetaminophen / Codeine for Severe Pain

Acute Bronchitis

Pain

Helps manage Pain

Chronic Pain

Helps manage Pain

Mild pain

Effectiveness

How Tuzistra Xr Affects Patients

Allergic reactions happen when a substance (allergen) interacts with the antibodies on mast cells and basophils. This triggers a series of events that cause the mast cells and basophils to release histamine and other chemicals. Histamine affects the body by causing itching, flushing, headache, and other symptoms. Chlorpheniramine is a medicine that works by blocking histamine receptors, which helps to relieve sneezing, itchy eyes, and a runny nose caused by allergies.

How Tuzistra Xr works in the body

Chlorpheniramine works by blocking your body's histamine receptors. Histamine is a compound that causes reactions in the body, and chlorpheniramine stops it from having any effect, providing temporary relief from the symptoms it causes.

When to interrupt dosage

The advocated measure of Tuzistra Xr is based on the identified ailment, for example upper respiratory symptoms, Coughing and Inflammation. The dosage varies, in accordance with the delivery methodology (e.g. Kit; Syrup - Oral or Liquid - Oral) specified in the table below.

Condition

Dosage

Administration

Airway secretion clearance therapy

, 10.0 mg/mL, 16.0 mg, 30.0 mg, 60.0 mg, 12.0 mg/mL, 7.5 mg/mL, 6.33 mg/mL, 6.0 mg/mL, 8.0 mg/mL, 6.3 mg/mL, 3.0 mg/mL, 3.5 mg/mL, 4.5 mg/mL, 5.0 mg/mL, 1.0 mg/mL, 15.0 mg, 30.0 mg/mL, 9.0 mg/mL, 15.0 mg/mL, 32.4 mg, 200.0 mg, 100.0 mg, 150.0 mg, 8.0 mg, 64.8 mg, 16.2 mg, 20.0 mg, 50.0 mg, 0.23 %, 54.3 mg, 14.7 mg/mL, 10.0 mg, 0.5 mg/mL, 9.0 mg, 2.0 mg/mL, 1.8 mg/mL, 20.0 mg/mL, 4.0 mg/mL, 2.4 mg/mL, 3.6 mg/mL, 3.3 mg/mL, 60.0 mg/mL, 25.0 mg/mL, 3.33 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, Tablet - Oral, Capsule - Oral, Capsule, Liquid, Liquid - Oral, Solution - Oral, Solution, Suspension - Oral, Suspension, Kit, Kit - Oral, Elixir, Elixir - Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release, Suspension, extended release - Oral, Intramuscular; Subcutaneous, Liquid - Intramuscular; Subcutaneous, Solution - Intramuscular; Subcutaneous

Coughing

, 10.0 mg/mL, 16.0 mg, 30.0 mg, 60.0 mg, 12.0 mg/mL, 7.5 mg/mL, 6.33 mg/mL, 6.0 mg/mL, 8.0 mg/mL, 6.3 mg/mL, 3.0 mg/mL, 3.5 mg/mL, 4.5 mg/mL, 5.0 mg/mL, 1.0 mg/mL, 15.0 mg, 30.0 mg/mL, 9.0 mg/mL, 15.0 mg/mL, 32.4 mg, 200.0 mg, 100.0 mg, 150.0 mg, 8.0 mg, 64.8 mg, 16.2 mg, 20.0 mg, 50.0 mg, 0.23 %, 54.3 mg, 14.7 mg/mL, 10.0 mg, 0.5 mg/mL, 9.0 mg, 2.0 mg/mL, 1.8 mg/mL, 20.0 mg/mL, 4.0 mg/mL, 2.4 mg/mL, 3.6 mg/mL, 3.3 mg/mL, 60.0 mg/mL, 25.0 mg/mL, 3.33 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, Tablet - Oral, Capsule - Oral, Capsule, Liquid, Liquid - Oral, Solution - Oral, Solution, Suspension - Oral, Suspension, Kit, Kit - Oral, Elixir, Elixir - Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release, Suspension, extended release - Oral, Intramuscular; Subcutaneous, Liquid - Intramuscular; Subcutaneous, Solution - Intramuscular; Subcutaneous

Catarrh

, 10.0 mg/mL, 16.0 mg, 30.0 mg, 60.0 mg, 12.0 mg/mL, 7.5 mg/mL, 6.33 mg/mL, 6.0 mg/mL, 8.0 mg/mL, 6.3 mg/mL, 3.0 mg/mL, 3.5 mg/mL, 4.5 mg/mL, 5.0 mg/mL, 1.0 mg/mL, 15.0 mg, 30.0 mg/mL, 9.0 mg/mL, 15.0 mg/mL, 32.4 mg, 200.0 mg, 100.0 mg, 150.0 mg, 8.0 mg, 64.8 mg, 16.2 mg, 20.0 mg, 50.0 mg, 0.23 %, 54.3 mg, 14.7 mg/mL, 10.0 mg, 0.5 mg/mL, 9.0 mg, 2.0 mg/mL, 1.8 mg/mL, 20.0 mg/mL, 4.0 mg/mL, 2.4 mg/mL, 3.6 mg/mL, 3.3 mg/mL, 60.0 mg/mL, 25.0 mg/mL, 3.33 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, Tablet - Oral, Capsule - Oral, Capsule, Liquid, Liquid - Oral, Solution - Oral, Solution, Suspension - Oral, Suspension, Kit, Kit - Oral, Elixir, Elixir - Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release, Suspension, extended release - Oral, Intramuscular; Subcutaneous, Liquid - Intramuscular; Subcutaneous, Solution - Intramuscular; Subcutaneous

Chronic Pain

, 10.0 mg/mL, 16.0 mg, 30.0 mg, 60.0 mg, 12.0 mg/mL, 7.5 mg/mL, 6.33 mg/mL, 6.0 mg/mL, 8.0 mg/mL, 6.3 mg/mL, 3.0 mg/mL, 3.5 mg/mL, 4.5 mg/mL, 5.0 mg/mL, 1.0 mg/mL, 15.0 mg, 30.0 mg/mL, 9.0 mg/mL, 15.0 mg/mL, 32.4 mg, 200.0 mg, 100.0 mg, 150.0 mg, 8.0 mg, 64.8 mg, 16.2 mg, 20.0 mg, 50.0 mg, 0.23 %, 54.3 mg, 14.7 mg/mL, 10.0 mg, 0.5 mg/mL, 9.0 mg, 2.0 mg/mL, 1.8 mg/mL, 20.0 mg/mL, 4.0 mg/mL, 2.4 mg/mL, 3.6 mg/mL, 3.3 mg/mL, 60.0 mg/mL, 25.0 mg/mL, 3.33 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, Tablet - Oral, Capsule - Oral, Capsule, Liquid, Liquid - Oral, Solution - Oral, Solution, Suspension - Oral, Suspension, Kit, Kit - Oral, Elixir, Elixir - Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release, Suspension, extended release - Oral, Intramuscular; Subcutaneous, Liquid - Intramuscular; Subcutaneous, Solution - Intramuscular; Subcutaneous

Acute Bronchitis

, 10.0 mg/mL, 16.0 mg, 30.0 mg, 60.0 mg, 12.0 mg/mL, 7.5 mg/mL, 6.33 mg/mL, 6.0 mg/mL, 8.0 mg/mL, 6.3 mg/mL, 3.0 mg/mL, 3.5 mg/mL, 4.5 mg/mL, 5.0 mg/mL, 1.0 mg/mL, 15.0 mg, 30.0 mg/mL, 9.0 mg/mL, 15.0 mg/mL, 32.4 mg, 200.0 mg, 100.0 mg, 150.0 mg, 8.0 mg, 64.8 mg, 16.2 mg, 20.0 mg, 50.0 mg, 0.23 %, 54.3 mg, 14.7 mg/mL, 10.0 mg, 0.5 mg/mL, 9.0 mg, 2.0 mg/mL, 1.8 mg/mL, 20.0 mg/mL, 4.0 mg/mL, 2.4 mg/mL, 3.6 mg/mL, 3.3 mg/mL, 60.0 mg/mL, 25.0 mg/mL, 3.33 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, Tablet - Oral, Capsule - Oral, Capsule, Liquid, Liquid - Oral, Solution - Oral, Solution, Suspension - Oral, Suspension, Kit, Kit - Oral, Elixir, Elixir - Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release, Suspension, extended release - Oral, Intramuscular; Subcutaneous, Liquid - Intramuscular; Subcutaneous, Solution - Intramuscular; Subcutaneous

Influenza

, 10.0 mg/mL, 16.0 mg, 30.0 mg, 60.0 mg, 12.0 mg/mL, 7.5 mg/mL, 6.33 mg/mL, 6.0 mg/mL, 8.0 mg/mL, 6.3 mg/mL, 3.0 mg/mL, 3.5 mg/mL, 4.5 mg/mL, 5.0 mg/mL, 1.0 mg/mL, 15.0 mg, 30.0 mg/mL, 9.0 mg/mL, 15.0 mg/mL, 32.4 mg, 200.0 mg, 100.0 mg, 150.0 mg, 8.0 mg, 64.8 mg, 16.2 mg, 20.0 mg, 50.0 mg, 0.23 %, 54.3 mg, 14.7 mg/mL, 10.0 mg, 0.5 mg/mL, 9.0 mg, 2.0 mg/mL, 1.8 mg/mL, 20.0 mg/mL, 4.0 mg/mL, 2.4 mg/mL, 3.6 mg/mL, 3.3 mg/mL, 60.0 mg/mL, 25.0 mg/mL, 3.33 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, Tablet - Oral, Capsule - Oral, Capsule, Liquid, Liquid - Oral, Solution - Oral, Solution, Suspension - Oral, Suspension, Kit, Kit - Oral, Elixir, Elixir - Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release, Suspension, extended release - Oral, Intramuscular; Subcutaneous, Liquid - Intramuscular; Subcutaneous, Solution - Intramuscular; Subcutaneous

Pain

, 10.0 mg/mL, 16.0 mg, 30.0 mg, 60.0 mg, 12.0 mg/mL, 7.5 mg/mL, 6.33 mg/mL, 6.0 mg/mL, 8.0 mg/mL, 6.3 mg/mL, 3.0 mg/mL, 3.5 mg/mL, 4.5 mg/mL, 5.0 mg/mL, 1.0 mg/mL, 15.0 mg, 30.0 mg/mL, 9.0 mg/mL, 15.0 mg/mL, 32.4 mg, 200.0 mg, 100.0 mg, 150.0 mg, 8.0 mg, 64.8 mg, 16.2 mg, 20.0 mg, 50.0 mg, 0.23 %, 54.3 mg, 14.7 mg/mL, 10.0 mg, 0.5 mg/mL, 9.0 mg, 2.0 mg/mL, 1.8 mg/mL, 20.0 mg/mL, 4.0 mg/mL, 2.4 mg/mL, 3.6 mg/mL, 3.3 mg/mL, 60.0 mg/mL, 25.0 mg/mL, 3.33 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, Tablet - Oral, Capsule - Oral, Capsule, Liquid, Liquid - Oral, Solution - Oral, Solution, Suspension - Oral, Suspension, Kit, Kit - Oral, Elixir, Elixir - Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release, Suspension, extended release - Oral, Intramuscular; Subcutaneous, Liquid - Intramuscular; Subcutaneous, Solution - Intramuscular; Subcutaneous

Fever

, 10.0 mg/mL, 16.0 mg, 30.0 mg, 60.0 mg, 12.0 mg/mL, 7.5 mg/mL, 6.33 mg/mL, 6.0 mg/mL, 8.0 mg/mL, 6.3 mg/mL, 3.0 mg/mL, 3.5 mg/mL, 4.5 mg/mL, 5.0 mg/mL, 1.0 mg/mL, 15.0 mg, 30.0 mg/mL, 9.0 mg/mL, 15.0 mg/mL, 32.4 mg, 200.0 mg, 100.0 mg, 150.0 mg, 8.0 mg, 64.8 mg, 16.2 mg, 20.0 mg, 50.0 mg, 0.23 %, 54.3 mg, 14.7 mg/mL, 10.0 mg, 0.5 mg/mL, 9.0 mg, 2.0 mg/mL, 1.8 mg/mL, 20.0 mg/mL, 4.0 mg/mL, 2.4 mg/mL, 3.6 mg/mL, 3.3 mg/mL, 60.0 mg/mL, 25.0 mg/mL, 3.33 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, Tablet - Oral, Capsule - Oral, Capsule, Liquid, Liquid - Oral, Solution - Oral, Solution, Suspension - Oral, Suspension, Kit, Kit - Oral, Elixir, Elixir - Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release, Suspension, extended release - Oral, Intramuscular; Subcutaneous, Liquid - Intramuscular; Subcutaneous, Solution - Intramuscular; Subcutaneous

upper respiratory symptoms

, 10.0 mg/mL, 16.0 mg, 30.0 mg, 60.0 mg, 12.0 mg/mL, 7.5 mg/mL, 6.33 mg/mL, 6.0 mg/mL, 8.0 mg/mL, 6.3 mg/mL, 3.0 mg/mL, 3.5 mg/mL, 4.5 mg/mL, 5.0 mg/mL, 1.0 mg/mL, 15.0 mg, 30.0 mg/mL, 9.0 mg/mL, 15.0 mg/mL, 32.4 mg, 200.0 mg, 100.0 mg, 150.0 mg, 8.0 mg, 64.8 mg, 16.2 mg, 20.0 mg, 50.0 mg, 0.23 %, 54.3 mg, 14.7 mg/mL, 10.0 mg, 0.5 mg/mL, 9.0 mg, 2.0 mg/mL, 1.8 mg/mL, 20.0 mg/mL, 4.0 mg/mL, 2.4 mg/mL, 3.6 mg/mL, 3.3 mg/mL, 60.0 mg/mL, 25.0 mg/mL, 3.33 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, Tablet - Oral, Capsule - Oral, Capsule, Liquid, Liquid - Oral, Solution - Oral, Solution, Suspension - Oral, Suspension, Kit, Kit - Oral, Elixir, Elixir - Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release, Suspension, extended release - Oral, Intramuscular; Subcutaneous, Liquid - Intramuscular; Subcutaneous, Solution - Intramuscular; Subcutaneous

Common Cold

, 10.0 mg/mL, 16.0 mg, 30.0 mg, 60.0 mg, 12.0 mg/mL, 7.5 mg/mL, 6.33 mg/mL, 6.0 mg/mL, 8.0 mg/mL, 6.3 mg/mL, 3.0 mg/mL, 3.5 mg/mL, 4.5 mg/mL, 5.0 mg/mL, 1.0 mg/mL, 15.0 mg, 30.0 mg/mL, 9.0 mg/mL, 15.0 mg/mL, 32.4 mg, 200.0 mg, 100.0 mg, 150.0 mg, 8.0 mg, 64.8 mg, 16.2 mg, 20.0 mg, 50.0 mg, 0.23 %, 54.3 mg, 14.7 mg/mL, 10.0 mg, 0.5 mg/mL, 9.0 mg, 2.0 mg/mL, 1.8 mg/mL, 20.0 mg/mL, 4.0 mg/mL, 2.4 mg/mL, 3.6 mg/mL, 3.3 mg/mL, 60.0 mg/mL, 25.0 mg/mL, 3.33 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, Tablet - Oral, Capsule - Oral, Capsule, Liquid, Liquid - Oral, Solution - Oral, Solution, Suspension - Oral, Suspension, Kit, Kit - Oral, Elixir, Elixir - Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release, Suspension, extended release - Oral, Intramuscular; Subcutaneous, Liquid - Intramuscular; Subcutaneous, Solution - Intramuscular; Subcutaneous

Pain

, 10.0 mg/mL, 16.0 mg, 30.0 mg, 60.0 mg, 12.0 mg/mL, 7.5 mg/mL, 6.33 mg/mL, 6.0 mg/mL, 8.0 mg/mL, 6.3 mg/mL, 3.0 mg/mL, 3.5 mg/mL, 4.5 mg/mL, 5.0 mg/mL, 1.0 mg/mL, 15.0 mg, 30.0 mg/mL, 9.0 mg/mL, 15.0 mg/mL, 32.4 mg, 200.0 mg, 100.0 mg, 150.0 mg, 8.0 mg, 64.8 mg, 16.2 mg, 20.0 mg, 50.0 mg, 0.23 %, 54.3 mg, 14.7 mg/mL, 10.0 mg, 0.5 mg/mL, 9.0 mg, 2.0 mg/mL, 1.8 mg/mL, 20.0 mg/mL, 4.0 mg/mL, 2.4 mg/mL, 3.6 mg/mL, 3.3 mg/mL, 60.0 mg/mL, 25.0 mg/mL, 3.33 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, Tablet - Oral, Capsule - Oral, Capsule, Liquid, Liquid - Oral, Solution - Oral, Solution, Suspension - Oral, Suspension, Kit, Kit - Oral, Elixir, Elixir - Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release, Suspension, extended release - Oral, Intramuscular; Subcutaneous, Liquid - Intramuscular; Subcutaneous, Solution - Intramuscular; Subcutaneous

Mild pain

, 10.0 mg/mL, 16.0 mg, 30.0 mg, 60.0 mg, 12.0 mg/mL, 7.5 mg/mL, 6.33 mg/mL, 6.0 mg/mL, 8.0 mg/mL, 6.3 mg/mL, 3.0 mg/mL, 3.5 mg/mL, 4.5 mg/mL, 5.0 mg/mL, 1.0 mg/mL, 15.0 mg, 30.0 mg/mL, 9.0 mg/mL, 15.0 mg/mL, 32.4 mg, 200.0 mg, 100.0 mg, 150.0 mg, 8.0 mg, 64.8 mg, 16.2 mg, 20.0 mg, 50.0 mg, 0.23 %, 54.3 mg, 14.7 mg/mL, 10.0 mg, 0.5 mg/mL, 9.0 mg, 2.0 mg/mL, 1.8 mg/mL, 20.0 mg/mL, 4.0 mg/mL, 2.4 mg/mL, 3.6 mg/mL, 3.3 mg/mL, 60.0 mg/mL, 25.0 mg/mL, 3.33 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, Tablet - Oral, Capsule - Oral, Capsule, Liquid, Liquid - Oral, Solution - Oral, Solution, Suspension - Oral, Suspension, Kit, Kit - Oral, Elixir, Elixir - Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release, Suspension, extended release - Oral, Intramuscular; Subcutaneous, Liquid - Intramuscular; Subcutaneous, Solution - Intramuscular; Subcutaneous

Pain

, 10.0 mg/mL, 16.0 mg, 30.0 mg, 60.0 mg, 12.0 mg/mL, 7.5 mg/mL, 6.33 mg/mL, 6.0 mg/mL, 8.0 mg/mL, 6.3 mg/mL, 3.0 mg/mL, 3.5 mg/mL, 4.5 mg/mL, 5.0 mg/mL, 1.0 mg/mL, 15.0 mg, 30.0 mg/mL, 9.0 mg/mL, 15.0 mg/mL, 32.4 mg, 200.0 mg, 100.0 mg, 150.0 mg, 8.0 mg, 64.8 mg, 16.2 mg, 20.0 mg, 50.0 mg, 0.23 %, 54.3 mg, 14.7 mg/mL, 10.0 mg, 0.5 mg/mL, 9.0 mg, 2.0 mg/mL, 1.8 mg/mL, 20.0 mg/mL, 4.0 mg/mL, 2.4 mg/mL, 3.6 mg/mL, 3.3 mg/mL, 60.0 mg/mL, 25.0 mg/mL, 3.33 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, Tablet - Oral, Capsule - Oral, Capsule, Liquid, Liquid - Oral, Solution - Oral, Solution, Suspension - Oral, Suspension, Kit, Kit - Oral, Elixir, Elixir - Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release, Suspension, extended release - Oral, Intramuscular; Subcutaneous, Liquid - Intramuscular; Subcutaneous, Solution - Intramuscular; Subcutaneous

Warnings

Tuzistra Xr Contraindications

Condition

Risk Level

Notes

Drug Metabolism, Poor, CYP2D6-Related

Do Not Combine

Respiratory Depression

Do Not Combine

Asthma

Do Not Combine

Chronic Pain

Do Not Combine

Adenoidectomy

Do Not Combine

Autoimmune Diseases

Do Not Combine

Intestinal Pseudo-Obstruction

Do Not Combine

Hypercarbia

Do Not Combine

Coughing

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Codeine may interact with Pulse Frequency

There are 20 known major drug interactions with Tuzistra Xr.

Common Tuzistra Xr Drug Interactions

Drug Name

Risk Level

Description

7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline

Major

The risk or severity of adverse effects can be increased when Codeine is combined with 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline.

Astemizole

Major

The metabolism of Astemizole can be decreased when combined with Codeine.

Azelastine

Major

Codeine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.

Benmoxin

Major

The risk or severity of adverse effects can be increased when Codeine is combined with Benmoxin.

Brofaromine

Major

The risk or severity of adverse effects can be increased when Codeine is combined with Brofaromine.

Tuzistra Xr Toxicity & Overdose Risk

The lowest toxic dose of the drug in rats, mice, and guinea pigs is 306mg/kg, 130mg/kg, and 198mg/kg respectively. It is also known to be a mild reproductive toxin for women of childbearing age.

image of a doctor in a lab doing drug, clinical research

Tuzistra Xr Novel Uses: Which Conditions Have a Clinical Trial Featuring Tuzistra Xr?

163 active trials are being conducted to assess the potential of Tuzistra Xr in alleviating Allergy to Vaccines, Ocular Irritation and Coughing Symptoms.

Condition

Clinical Trials

Trial Phases

Mild pain

0 Actively Recruiting

Pain

0 Actively Recruiting

Pain

0 Actively Recruiting

upper respiratory symptoms

0 Actively Recruiting

Pain

0 Actively Recruiting

Influenza

29 Actively Recruiting

Not Applicable, Phase 4, Phase 2, Phase 1, Phase 3

Chronic Pain

130 Actively Recruiting

Not Applicable, Phase 4, Phase 2, Phase 3, Early Phase 1, Phase 1

Common Cold

3 Actively Recruiting

Not Applicable

Coughing

0 Actively Recruiting

Airway secretion clearance therapy

0 Actively Recruiting

Catarrh

0 Actively Recruiting

Fever

2 Actively Recruiting

Not Applicable, Phase 4

Acute Bronchitis

7 Actively Recruiting

Phase 4, Not Applicable, Phase 3, Early Phase 1

Tuzistra Xr Reviews: What are patients saying about Tuzistra Xr?

5

Patient Review

12/13/2016

Tuzistra Xr for Cough

Don't bother with this Tuzistra XR suspension; it's just sugar water. I paid $116 for it and got zero relief from my bronchitis cough. Stick with Promethazine instead.

5

Patient Review

1/18/2017

Tuzistra Xr for Cold Symptoms

This medication worked great for me and cleared up my infection quickly.

5

Patient Review

11/20/2019

Tuzistra Xr for Stuffy Nose

This medication is way too expensive and not covered by my insurance. Unfortunately, I had to stop taking it after just one and a half days because it made me feel nauseous. The over the counter medication recommended by the pharmacist was much cheaper and worked just as well.

4

Patient Review

2/25/2017

Tuzistra Xr for Cough

I had a pretty severe case of the flu, so I decided to try this liquid medication. You only have to take it once a day, which was really convenient for me. It worked wonders and I was able to get back to my usual routine in no time.

4

Patient Review

6/10/2020

Tuzistra Xr for Cough

This medication caused a little drowsiness but was great to take at night. It helped me sleep and was definitely worth the money, even without insurance.

3.3

Patient Review

4/13/2017

Tuzistra Xr for Cold Symptoms

I was really disappointed in this treatment. It did nothing to help my cough, unfortunately.

2

Patient Review

3/21/2017

Tuzistra Xr for Cough

This stopped my constant coughing at night, which was great. Only needed to use one teaspoon.

2

Patient Review

1/9/2018

Tuzistra Xr for Cough

While the medication did achieve its intended goal of stopping my coughing, I unfortunately had a severe reaction to it in the form of hives all over my body.

1

Patient Review

11/22/2016

Tuzistra Xr for Cold Symptoms

1

Patient Review

11/29/2016

Tuzistra Xr for Cough

I was really disappointed with this medication. Not only is it expensive, but it also didn't work for me at all. I would not recommend it to anyone.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about tuzistra xr

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is tussionex with codeine?

"Chlorpheniramine is an antihistamine that works by preventing the effects of a substance called histamine, which is produced by the body.

This combination product is used to treat coughs and other symptoms caused by the common cold or allergies. It contains two medications: hydrocodone, an opioid cough suppressant that acts on the cough center of the brain, and chlorpheniramine, an antihistamine that works by preventing the effects of histamine."

Answered by AI

Does Calmylin have codeine?

"Pheniramine belongs to the group of medications called antihistamines. Guaifenesin belongs to the group of medications called mucolytics.

This combination product contains three medications: codeine, pheniramine, and guaifenesin. Codeine is a narcotic analgesic and cough suppressant. Pheniramine is an antihistamine. Guaifenesin is a mucolytic."

Answered by AI

What is Tuzistra XR for?

"TUZISTRA XR is a prescription medicine that you can use to treat cough and respiratory symptoms that you can have with allergies or a common cold. TUZISTRA XR is a combination of two medicines, codeine and chlorpheniramine. Codeine is a narcotic cough suppressant while chlorpheniramine is an antihistamine."

Answered by AI

What is Tuzistra used for?

"This medication is used to relief symptoms associated with colds and coughs. It may be used on its own or in conjunction with other medicines. It belongs to a class of drugs known as antitussives and narcotic combos. It is not currently known if it is safe and effective for use in children under the age of 18."

Answered by AI

Clinical Trials for Tuzistra Xr

Image of AltaSciences, Inc in Cypress, United States.

SBS-147 Safety Study

18 - 55
All Sexes
Cypress, CA

This study is part of the HEAL Initiative supported by the NIH. The purpose of this study is to learn how safe the study drug, SBS-147, is and how people's bodies respond to and process it. Researchers will also look for any side effects that may occur when taking SBS-147. Some participants will receive SBS-147, and others will receive a placebo, which looks the same but does not contain any medicine. This helps researchers fairly compare results. The study includes two parts: Single-Dose Group, where Participants receive SBS-147 or placebo one time. Multiple-Dose Group, where Participants receive SBS-147 or placebo once or twice daily for 7 days.

Phase 1
Waitlist Available

AltaSciences, Inc

Jeff Reich, MD

Sparian Biosciences, Inc

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We made a collection of clinical trials featuring Tuzistra Xr, we think they might fit your search criteria.
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Image of Vanderbilt University Medical Center in Nashville, United States.

Lidocaine Infusions for Postoperative Pain

18+
All Sexes
Nashville, TN

The goal of this single-center, pragmatic, randomized, blinded, placebo-controlled trial is to evaluate the impact of intravenous (IV) lidocaine within the existing Enhanced Recovery After Surgery (ERAS)program on outcomes in patients after major abdominal surgery. The main questions the trial aims to answer are: The primary hypothesis is that utilization of IV lidocaine as part of a perioperative multimodal pain regimen will result in a reduction in hospital Case Mix Index-Adjusted Resource Length of Stay (CARLOS). The secondary hypotheses are that lidocaine infusion will result in a reduction in total inpatient opioid consumption (oral morphine milligram equivalents, oMMEs) and pain scores, and improved surgical outcomes (including return of bowel function, ileus, nausea, rapid responses called, surgical site infections, and ICU transfers), while also having minimal incidence of side effects (including double/blurry vision, tinnitus, sedation, and adverse events requiring early cessation).

Phase 4
Waitlist Available

Vanderbilt University Medical Center

Danial Shams, MD

Image of Baylor College of Medicine/Texas Children's Hospital in Austin, United States.

Guided Imagery Therapy for Abdominal Pain

7 - 12
All Sexes
Austin, TX

Chronic abdominal pain is common among children, and the majority of cases are attributed to functional abdominal pain disorders. One approach to treating these disorders is by using psychological therapies. This clinical trial aims to see how well pre-recorded guided imagery therapy sessions help children's abdominal pain when delivered via a mobile application (app) on a smartphone or tablet. Participants will complete a baseline abdominal pain and stooling diary to determine eligibility, as well as other surveys. Eligible participants will be given access to the guided imagery therapy mobile application. This intervention asks participants to listen to a 10- to 15-minute GIT session 5 out of 7 days per week for 8 weeks, in addition to their usual care for their abdominal pain. Then, participants will complete another abdominal pain and stooling diary, along with other psychometric surveys, at the end of this intervention period. Participants will also collect another diary and surveys 3 months post-treatment.

Waitlist Available
Has No Placebo

Baylor College of Medicine/Texas Children's Hospital (+1 Sites)

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