What is Trexall
MethotrexateThe Generic name of this drug
Treatment SummaryMethotrexate is a type of drug that stops the body from making certain enzymes that help with cell growth and inflammation. It is used to treat arthritis, breast cancer, and non-Hodgkin's lymphoma. It is only prescribed if other treatments have not worked or if the patient cannot tolerate those treatments. Methotrexate was approved by the FDA in 1953.
Rheumatrex Dose Packis the brand name
Trexall Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Rheumatrex Dose Pack
Methotrexate
1953
137
Effectiveness
How Trexall Affects PatientsMethotrexate stops cells from dividing and reduces inflammation. It usually needs to be taken once a week and has a small margin of safety. Do not take methotrexate on a daily basis.
How Trexall works in the bodyMethotrexate targets the enzymes that help cells reproduce, preventing them from dividing. In rheumatoid arthritis, methotrexate polyglutamates specifically inhibit an enzyme called AICART. This leads to a build-up of adenosine triphosphate and adenosine in the area around the cells, which helps reduce inflammation.
When to interrupt dosage
The amount of Trexall is contingent upon the diagnosed condition, including Uveitis, Polymyositis and nonleukemic meningeal cancer. The degree of dosage likewise differs according to the method of delivery featured in the table beneath.Condition
Dosage
Administration
Sarcoma
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
prophylaxis of Meningeal leukemia
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Pregnancy
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Medically induced abortion
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Acute Lymphoblastic Leukemia
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Hematopoietic stem cells
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Crohn's Disease
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Soft Tissue Sarcoma
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Psoriasis
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Lupus
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Acute Promyelocytic Leukemia
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Rheumatoid Arthritis
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Prophylaxis against graft versus host disease
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Extrauterine Pregnancy
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Dermatomyositis (DM)
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Erythema Induratum
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Squamous cell carcinoma
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Bladder Cancer
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Takayasu Arteritis
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Meningeal leukemia
, 275.0 mg/mL, 1000.0 mg, 2.5 mg, 300.0 mg/mL, 125.0 mg/mL, 150.0 mg/mL, 100.0 mg/mL, 50.0 mg, 10.0 mg/mL, 75.0 mg/mL, 20.0 mg/mL, 2.5 mg/mL, 225.0 mg/mL, 200.0 mg/mL, 25.0 mg/mL, 175.0 mg/mL, 15.0 mg/mL, 250.0 mg/mL, 15.0 mg, 20.0 mg, 7.5 mg, 12.5 mg, 25.0 mg, 17.5 mg, 10.0 mg, 5.0 mg, 22.5 mg, 2.0 mg/mL
, Solution - Intra-arterial; Intramuscular; Intravenous, Tablet, Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intravenous, Intramuscular; Intrathecal; Intravenous, Injection, solution - Subcutaneous, Solution, Injection, solution, Injection, powder, lyophilized, for solution, Tablet, film coated - Oral, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet - Oral, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Liquid - Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Tablet, film coated, Solution - Intravenous, Solution - Subcutaneous, Liquid, Intramuscular; Intrathecal; Intravenous; Subcutaneous, Powder, for solution, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution - Oral, Injection, solution - Intramuscular; Intrathecal; Intravenous; Subcutaneous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection
Warnings
Trexall ContraindicationsCondition
Risk Level
Notes
Non Neoplastic Condition
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Methotrexate may interact with Toxoplasma Infections
Common Trexall Drug Interactions
Drug Name
Risk Level
Description
2-Methoxyethanol
Major
The risk or severity of adverse effects can be increased when Methotrexate is combined with 2-Methoxyethanol.
9-(N-methyl-L-isoleucine)-cyclosporin A
Major
The risk or severity of adverse effects can be increased when Methotrexate is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Abetimus
Major
The risk or severity of adverse effects can be increased when Methotrexate is combined with Abetimus.
Acteoside
Major
The risk or severity of adverse effects can be increased when Methotrexate is combined with Acteoside.
Aldosterone
Major
The risk or severity of adverse effects can be increased when Methotrexate is combined with Aldosterone.
Trexall Toxicity & Overdose RiskThe lowest toxic dose of this drug in rats is 135mg/kg and in mice is 146mg/kg. Overdosing on this drug may cause low blood cell counts, mouth sores, nausea, vomiting, stomach ulcers, and bleeding from the digestive tract. If a patient overdoses, they should be treated with glucarpidase and should not be given leucovorin for 2 hours before or after glucarpidase.
Trexall Novel Uses: Which Conditions Have a Clinical Trial Featuring Trexall?
There are 764 active investigations into the potential of Trexall to treat Uveitis, Small Cell Lung Cancer and Soft Tissue Sarcoma.Condition
Clinical Trials
Trial Phases
Head and Neck Carcinoma
20 Actively Recruiting
Phase 3, Phase 2, Not Applicable, Phase 1, Early Phase 1
Squamous cell carcinoma
8 Actively Recruiting
Not Applicable, Phase 1, Phase 2
Multiple Sclerosis
198 Actively Recruiting
Phase 3, Not Applicable, Phase 2, Phase 1, Phase 4, Early Phase 1
Small Cell Lung Cancer
62 Actively Recruiting
Phase 2, Phase 3, Phase 1, Not Applicable, Phase 4, Early Phase 1
Hydatidiform Moles
0 Actively Recruiting
Pregnancy
42 Actively Recruiting
Phase 3, Not Applicable, Phase 2, Phase 1, Phase 4
Crohn's Disease
36 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4
Lupus
64 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 3, Phase 4, Early Phase 1
Chronic Graft Versus Host Disease
32 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Phase 3, Early Phase 1
Soft Tissue Sarcoma
63 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 3, Phase 4, Early Phase 1
Acute Lymphoblastic Leukemia
140 Actively Recruiting
Phase 2, Phase 3, Phase 1, Not Applicable, Early Phase 1
Dermatomyositis (DM)
0 Actively Recruiting
Uveitis
13 Actively Recruiting
Phase 2, Phase 3, Phase 4, Not Applicable
Rheumatoid Arthritis
0 Actively Recruiting
Prophylaxis against graft versus host disease
0 Actively Recruiting
Polymyositis
3 Actively Recruiting
Early Phase 1, Phase 2, Phase 3
Erythema Induratum
0 Actively Recruiting
Bladder Cancer
108 Actively Recruiting
Phase 3, Phase 2, Not Applicable, Phase 1, Early Phase 1
Lymphoma
8 Actively Recruiting
Phase 2, Early Phase 1, Phase 1
Meningeal leukemia
0 Actively Recruiting
Trexall Reviews: What are patients saying about Trexall?
5Patient Review
5/19/2010 I've used this treatment for two years now and it has worked well for me. I'm currently taking 8 2.5 mg doses per week, but I recently tried cutting down to 6 because I was feeling so well and didn't like the possible side effects. However, I found that my pain increased and my mobility decreased, so with my doctor's approval, I will probably go back up to 8 doses per week.
4.3Patient Review
7/20/2009 I've had RA for a decade and been on methotrexate off-and-on for a couple years now. I'm currently 1.5 years into another cycle and it's helping moderately well; better than most other options available to me, at any rate. That said, it does make me tired and nauseous every dosage, which isn't ideal.
4.3Patient Review
7/19/2013 I've had some indigestion, reflux and chest pains since starting this medication, but it's only been three doses.
3.7Patient Review
10/24/2008 I've been taking methotrexate for nearly a year now, and I don't see any change in my current psoriasis areas. If anything, it seems like I'm getting new breakouts.
3Patient Review
10/23/2012 Please be aware that long-term use of this drug may lead to diabetes. My husband developed blue toe syndrome and had to have a toe removed as a result.
2Patient Review
10/3/2008Patient Q&A Section about trexall
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What are the common side effects of methotrexate?
"Dizziness, drowsiness, headache, swollen, tender gums, decreased appetite, reddened eyes, and hair loss are all potential side effects of the medication."
Answered by AI
How long does it take for Trexall to work?
"Methotrexate requires regular laboratory monitoring in order to keep track of blood counts and the patient's liver function. The drug usually produces improvements in arthritis and other conditions within three to six weeks, although the full benefits of the drug may not be seen for 12 weeks."
Answered by AI
What is the difference between Trexall and methotrexate?
"Trexall is a brand-name medication that contains the active drug methotrexate. Methotrexate is the ingredient that makes Trexall work. Generic forms of methotrexate tablets are available, but these come in a lower strength (2.5 mg) than Trexall."
Answered by AI
What is the drug Trexall used for?
"Methotrexate is a medication that is used as a treatment for cancer, severe psoriasis, or rheumatoid arthritis. It is typically given to patients who have not responded well to other forms of treatment."
Answered by AI