Trexall

Polymyositis, Uveitis, Prophylaxis against graft versus host disease + 27 more
Treatment
20 Active Studies for Trexall

What is Trexall

MethotrexateThe Generic name of this drug
Treatment SummaryMethotrexate is a type of drug that stops the body from making certain enzymes that help with cell growth and inflammation. It is used to treat arthritis, breast cancer, and non-Hodgkin's lymphoma. It is only prescribed if other treatments have not worked or if the patient cannot tolerate those treatments. Methotrexate was approved by the FDA in 1953.
Methotrexateis the brand name
image of different drug pills on a surface
Trexall Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Methotrexate
Methotrexate
1953
137

Effectiveness

How Trexall Affects PatientsMethotrexate stops cells from dividing and reduces inflammation. It usually needs to be taken once a week and has a small margin of safety. Do not take methotrexate on a daily basis.
How Trexall works in the bodyMethotrexate targets the enzymes that help cells reproduce, preventing them from dividing. In rheumatoid arthritis, methotrexate polyglutamates specifically inhibit an enzyme called AICART. This leads to a build-up of adenosine triphosphate and adenosine in the area around the cells, which helps reduce inflammation.

When to interrupt dosage

The amount of Trexall is contingent upon the diagnosed condition, including Uveitis, Polymyositis and nonleukemic meningeal cancer. The degree of dosage likewise differs according to the method of delivery featured in the table beneath.
Condition
Dosage
Administration
Takayasu Arteritis
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Medically induced abortion
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Acute Promyelocytic Leukemia
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Leukemia
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Leukemia
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Arthritis, Juvenile
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Multiple Sclerosis
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Crohn's Disease
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Lupus
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Gestational Trophoblastic Disease
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Uveitis
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Acute Lymphoblastic Leukemia
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Hematopoietic stem cells
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Polymyositis
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Chemotherapy
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Psoriasis
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Lymphoma, Non-Hodgkin
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Dermatomyositis
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Breast Cancer
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis
Rheumatoid Arthritis
25.0 mg/mL, , 2.5 mg, 100.0 mg/mL, 25.0 mg, 7.5 mg, 10.0 mg, 15.0 mg, 20.0 mg, 50.0 mg, 150.0 mg/mL, 200.0 mg/mL, 250.0 mg/mL, 75.0 mg/mL, 125.0 mg/mL, 225.0 mg/mL, 175.0 mg/mL, 12.5 mg, 17.5 mg, 22.5 mg, 5.0 mg, 1000.0 mg, 2.5 mg/mL, 275.0 mg/mL, 300.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 15.0 mg/mL, 2.0 mg/mL
, Injection, Injection - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intra-arterial; Intramuscular; Intrathecal; Intravenous, Injection, solution, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Oral, Tablet, Tablet - Oral, Intra-arterial; Intramuscular; Intravenous, Injection, solution - Intra-arterial; Intramuscular; Intravenous, Solution, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Intra-arterial; Intramuscular; Intravenous, Liquid, Liquid - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Liquid - Intramuscular; Intrathecal; Intravenous, Intramuscular; Intrathecal; Intravenous, Powder, for solution - Intramuscular; Intrathecal; Intravenous, Powder, for solution, Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous; Intraventricular, Powder, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Intravenous, Liquid - Intravenous, Subcutaneous, Injection, solution - Subcutaneous, Solution - Subcutaneous, Tablet, film coated - Oral, Tablet, film coated, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intra-arterial; Intramuscular; Intrathecal; Intravenous, Solution - Oral, Solution - Intravenous, Intra-arterial; Intramuscular; Intrathecal; Iontophoresis, Injection, solution - Intra-arterial; Intramuscular; Intrathecal; Iontophoresis

Warnings

Trexall Contraindications
Condition
Risk Level
Notes
Non Neoplastic Condition
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Methotrexate may interact with Pulse Frequency
There are 20 known major drug interactions with Trexall.
Common Trexall Drug Interactions
Drug Name
Risk Level
Description
2-Methoxyethanol
Major
The risk or severity of adverse effects can be increased when Methotrexate is combined with 2-Methoxyethanol.
9-(N-methyl-L-isoleucine)-cyclosporin A
Major
The risk or severity of adverse effects can be increased when Methotrexate is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Abetimus
Major
The risk or severity of adverse effects can be increased when Methotrexate is combined with Abetimus.
Acteoside
Major
The risk or severity of adverse effects can be increased when Methotrexate is combined with Acteoside.
Aldosterone
Major
The risk or severity of adverse effects can be increased when Methotrexate is combined with Aldosterone.
Trexall Toxicity & Overdose RiskThe lowest toxic dose of this drug in rats is 135mg/kg and in mice is 146mg/kg. Overdosing on this drug may cause low blood cell counts, mouth sores, nausea, vomiting, stomach ulcers, and bleeding from the digestive tract. If a patient overdoses, they should be treated with glucarpidase and should not be given leucovorin for 2 hours before or after glucarpidase.
image of a doctor in a lab doing drug, clinical research

Trexall Novel Uses: Which Conditions Have a Clinical Trial Featuring Trexall?

There are 764 active investigations into the potential of Trexall to treat Uveitis, Small Cell Lung Cancer and Soft Tissue Sarcoma.
Condition
Clinical Trials
Trial Phases
Multiple Sclerosis
120 Actively Recruiting
Phase 3, Not Applicable, Phase 4, Phase 2, Phase 1, Early Phase 1
Bladder Cancer
105 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 3, Early Phase 1
Lupus
57 Actively Recruiting
Phase 2, Phase 1, Not Applicable, Phase 3, Phase 4
Acute Lymphoblastic Leukemia
119 Actively Recruiting
Phase 1, Phase 2, Phase 3, Not Applicable, Early Phase 1, Phase 4
Non-Hodgkin's Lymphoma
124 Actively Recruiting
Phase 1, Phase 2, Early Phase 1, Not Applicable, Phase 3, Phase 4
Rheumatoid Arthritis
54 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1
Soft Tissue Sarcoma
59 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 3, Phase 4, Early Phase 1
Hematopoietic stem cells
3 Actively Recruiting
Early Phase 1, Phase 1, Phase 2
Takayasu Arteritis
0 Actively Recruiting
Psoriasis
0 Actively Recruiting
Mycosis Fungoides
0 Actively Recruiting
Chemotherapy
3 Actively Recruiting
Phase 1, Phase 3, Not Applicable
Crohn's Disease
43 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4
Acute Promyelocytic Leukemia
0 Actively Recruiting
Breast Cancer
26 Actively Recruiting
Phase 2, Phase 1, Not Applicable
Sarcoma
0 Actively Recruiting
Lymphoma
5 Actively Recruiting
Phase 1, Phase 2
Gestational Trophoblastic Disease
0 Actively Recruiting
Pregnancy, Ectopic
0 Actively Recruiting
Polymyositis
4 Actively Recruiting
Phase 2, Phase 3

Trexall Reviews: What are patients saying about Trexall?

5Patient Review
5/19/2010
Trexall for Rheumatoid Arthritis
I've used this treatment for two years now and it has worked well for me. I'm currently taking 8 2.5 mg doses per week, but I recently tried cutting down to 6 because I was feeling so well and didn't like the possible side effects. However, I found that my pain increased and my mobility decreased, so with my doctor's approval, I will probably go back up to 8 doses per week.
4.3Patient Review
7/20/2009
Trexall for Rheumatoid Arthritis
I've had RA for a decade and been on methotrexate off-and-on for a couple years now. I'm currently 1.5 years into another cycle and it's helping moderately well; better than most other options available to me, at any rate. That said, it does make me tired and nauseous every dosage, which isn't ideal.
4.3Patient Review
7/19/2013
Trexall for Inflammation of Skin and Muscles All Over the Body
I've had some indigestion, reflux and chest pains since starting this medication, but it's only been three doses.
3.7Patient Review
10/24/2008
Trexall for Rheumatoid Arthritis
I've been taking methotrexate for nearly a year now, and I don't see any change in my current psoriasis areas. If anything, it seems like I'm getting new breakouts.
3Patient Review
10/23/2012
Trexall for Rheumatoid Arthritis
Please be aware that long-term use of this drug may lead to diabetes. My husband developed blue toe syndrome and had to have a toe removed as a result.
View All Reviews
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Patient Q&A Section about trexall

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the common side effects of methotrexate?

"Dizziness, drowsiness, headache, swollen, tender gums, decreased appetite, reddened eyes, and hair loss are all potential side effects of the medication."

Answered by AI

How long does it take for Trexall to work?

"Methotrexate requires regular laboratory monitoring in order to keep track of blood counts and the patient's liver function. The drug usually produces improvements in arthritis and other conditions within three to six weeks, although the full benefits of the drug may not be seen for 12 weeks."

Answered by AI

What is the difference between Trexall and methotrexate?

"Trexall is a brand-name medication that contains the active drug methotrexate. Methotrexate is the ingredient that makes Trexall work. Generic forms of methotrexate tablets are available, but these come in a lower strength (2.5 mg) than Trexall."

Answered by AI

What is the drug Trexall used for?

"Methotrexate is a medication that is used as a treatment for cancer, severe psoriasis, or rheumatoid arthritis. It is typically given to patients who have not responded well to other forms of treatment."

Answered by AI

Clinical Trials for Trexall

Have you considered Trexall clinical trials? We made a collection of clinical trials featuring Trexall, we think they might fit your search criteria.
Have you considered Trexall clinical trials? We made a collection of clinical trials featuring Trexall, we think they might fit your search criteria.
Have you considered Trexall clinical trials? We made a collection of clinical trials featuring Trexall, we think they might fit your search criteria.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
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