Tolazamide

Type 2 Diabetes
Treatment
1 FDA approval
20 Active Studies for Tolazamide

What is Tolazamide

TolazamideThe Generic name of this drug
Treatment SummaryGlipizide is a medication used to lower blood sugar levels in people with diabetes. It works similarly to the diabetes medication chlorpropamide.
Tolazamideis the brand name
Tolazamide Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Tolazamide
Tolazamide
1995
11

Approved as Treatment by the FDA

Tolazamide, otherwise called Tolazamide, is approved by the FDA for 1 uses like Type 2 Diabetes .
Type 2 Diabetes
Helps manage Type 2 Diabetes Mellitus

Effectiveness

How Tolazamide Affects PatientsTolazamide is a type of medication that helps to lower blood sugar levels. It does this by stimulating the pancreas to release insulin. This effect usually lessens over time, so sometimes other medications may need to be used. Tolazamide may also be effective for people who have become unresponsive to other drugs in the same class. On top of lowering blood sugar levels, it also helps the body get rid of extra water.
How Tolazamide works in the bodySulfonylureas help your pancreas release insulin. They do this by blocking the flow of potassium in and out of the cells. This causes the cells to become more electrically charged, triggering an influx of calcium ions. The calcium ions signal the release of insulin from the pancreas.

When to interrupt dosage

The suggested dosage of Tolazamide is contingent upon the determined condition. The quantity of dosage changes in accordance with the technique of delivery (e.g. Oral or Tablet - Oral) listed in the table below.
Condition
Dosage
Administration
Type 2 Diabetes
500.0 mg, 100.0 mg, , 250.0 mg
Oral, Tablet - Oral, , Tablet

Warnings

Tolazamide Contraindications
Condition
Risk Level
Notes
Diabetic Ketoacidosis
Do Not Combine
in Type I diabetes, as sole therapy
Do Not Combine
There are 20 known major drug interactions with Tolazamide.
Common Tolazamide Drug Interactions
Drug Name
Risk Level
Description
(R)-warfarin
Minor
Tolazamide may increase the anticoagulant activities of (R)-warfarin.
(S)-Warfarin
Minor
Tolazamide may increase the anticoagulant activities of (S)-Warfarin.
Abacavir
Minor
Tolazamide may decrease the excretion rate of Abacavir which could result in a higher serum level.
Abrocitinib
Minor
The metabolism of Abrocitinib can be decreased when combined with Tolazamide.
Aclidinium
Minor
Tolazamide may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Tolazamide Toxicity & Overdose RiskTaking too much of a sulfonylurea drug can result in dangerously low blood sugar levels, which can cause dizziness, confusion, seizures, and even loss of consciousness. These symptoms require urgent medical attention.

Tolazamide Novel Uses: Which Conditions Have a Clinical Trial Featuring Tolazamide?

162 active clinical trials are currently being conducted to investigate the potential of Tolazamide to manage Type 2 Diabetes.
Condition
Clinical Trials
Trial Phases
Type 2 Diabetes
175 Actively Recruiting
Phase 2, Not Applicable, Phase 4, Early Phase 1, Phase 1, Phase 3

Tolazamide Reviews: What are patients saying about Tolazamide?

2.7Patient Review
4/5/2018
Tolazamide for Type 2 Diabetes Mellitus
Beware of long-term use of this medication. I nearly died as a result of liver failure after taking it for several months. The doctors determined that the diabetes medication Tolazamide was to blame. Please consult with your doctor and do your research before starting any new medications.

Patient Q&A Section about tolazamide

Is Tolazamide available in the USA?

"Tolazamide is no longer available in the United States as of September 15, 2020." - Anonymous Online Contributor

Unverified Answer

Which ring is present in Tolazamide?

"Tolazamide is one type of N-sulfonylurea that is 1-tosylurea in which the nitrogen at position 3 has an azepan-1-yl group instead of a hydrogen atom. It is used as a hypoglycemic agent to treat type 2 diabetes mellitus." - Anonymous Online Contributor

Unverified Answer

What is Tolazamide used for?

"Tolazamide is used to treat high blood sugar levels caused by type 2 diabetes mellitus. Type 2 diabetes is a condition in which your body does not work properly to store excess sugar and the sugar remains in your bloodstream." - Anonymous Online Contributor

Unverified Answer

What is the brand name of Tolazamide?

"TOLINASE tablets can be used as a complement to diet to help lower blood sugar in patients with non-insulin dependent diabetes mellitus (Type II) who cannot adequately control their hyperglycemia with diet alone." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Clinical Trials for Tolazamide

Have you considered Tolazamide clinical trials? We made a collection of clinical trials featuring Tolazamide, we think they might fit your search criteria.
Have you considered Tolazamide clinical trials? We made a collection of clinical trials featuring Tolazamide, we think they might fit your search criteria.
Have you considered Tolazamide clinical trials? We made a collection of clinical trials featuring Tolazamide, we think they might fit your search criteria.
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Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
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