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What is Tindamax
TinidazoleThe Generic name of this drug
Treatment SummaryMetronidazole is a medication used to treat infections caused by the microorganisms Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia.
Tindamaxis the brand name
Tindamax Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Tindamax
Tinidazole
2004
24
Approved as Treatment by the FDA
Tinidazole, commonly known as Tindamax, is approved by the FDA for 4 uses including Ameboma and Giardiasis .Ameboma
Giardiasis
Bacterial Vaginosis
Trichomonas Vaginitis
Effectiveness
How Tindamax Affects PatientsTinidazole is a drug used to treat infections caused by protozoa, which are small, single-celled organisms. Tinidazole has been proven to be effective against the protozoa Trichomonas vaginalis, Giardia duodenalis, and Entamoeba histolytica. It does not appear to work against the bacteria that usually live in the vagina.
How Tindamax works in the bodyTinidazole is a medicine that helps to kill protozoa. When taken, it's converted into a toxic free radical within the protozoa. This free radical binds to the protozoa's DNA, causing damage and cell death. It's not known exactly how tinidazole works against Giardia and Entamoeba species, but it is thought to work in a similar way.
When to interrupt dosage
The proposed measure of Tindamax is contingent upon the diagnosed disorder, including Urethritis, Sexually Transmitted Diseases and Trichomoniasis. The quantity of dosage shifts, in line with the delivery approach (e.g. Tablet, film coated or Tablet, film coated - Oral) specified in the table below.Condition
Dosage
Administration
Sexual Assault
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Giardiasis
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Sexually Transmitted Diseases
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Mixed Vaginal Infections
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Trichomonas Vaginalis Infection
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Vaginal Candidiasis
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Sexually Transmitted Diseases
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Bacterial Vaginosis
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Trichomonas Vaginitis
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Urethritis
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Ameboma
500.0 mg, , 250.0 mg
Oral, , Tablet, film coated - Oral, Tablet, film coated, Tablet, Tablet - Oral
Warnings
Tindamax ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Tinidazole may interact with Pulse Frequency
Common Tindamax Drug Interactions
Drug Name
Risk Level
Description
Disulfiram
Major
The risk or severity of adverse effects can be increased when Tinidazole is combined with Disulfiram.
Ethanol
Major
The risk or severity of adverse effects can be increased when Tinidazole is combined with Ethanol.
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Tinidazole.
Abacavir
Minor
Tinidazole may decrease the excretion rate of Abacavir which could result in a higher serum level.
Aclidinium
Minor
Tinidazole may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Tindamax Toxicity & Overdose RiskThere have been no reported overdoses of tinidazole in humans. However, testing on mice and rats has found that the toxic amount is greater than 3,600 mg/kg when taken orally, and greater than 2,300 mg/kg when taken through the abdomen in mice. In rats, the toxic amount is greater than 2,000mg/kg for both oral and intraperitoneal administration.
Tindamax Novel Uses: Which Conditions Have a Clinical Trial Featuring Tindamax?
11 active trials are presently assessing the potential of Tindamax to manage Trichomoniasis, Sexually Transmitted Diseases and Trichomonas Vaginalis Infection.Condition
Clinical Trials
Trial Phases
Trichomonas Vaginitis
1 Actively Recruiting
Phase 2
Vaginal Candidiasis
0 Actively Recruiting
Sexually Transmitted Diseases
0 Actively Recruiting
Trichomonas Vaginalis Infection
0 Actively Recruiting
Giardiasis
0 Actively Recruiting
Ameboma
0 Actively Recruiting
Mixed Vaginal Infections
0 Actively Recruiting
Urethritis
0 Actively Recruiting
Sexual Assault
7 Actively Recruiting
Not Applicable
Bacterial Vaginosis
3 Actively Recruiting
Not Applicable, Phase 2, Early Phase 1
Sexually Transmitted Diseases
0 Actively Recruiting
Tindamax Reviews: What are patients saying about Tindamax?
5Patient Review
3/31/2019 This medication is really great. I didn't experience any negative side effects and it worked very quickly. Much easier on the body than other treatments like Flagyl.
5Patient Review
11/8/2018 Despite my initial anxiety about taking this medication, it really helped me. I would recommend it to anyone dealing with similar issues.
5Patient Review
8/10/2011 I was initially hesitant to try this medication because of the negative reviews I had read. However, I'm glad I did. Not only did it clear up my infection, but I also didn't experience any adverse side effects.
4.7Patient Review
2/15/2012 I'm on my second day of taking this medication, and I'm feeling much better. The symptoms have decreased significantly, and I haven't experienced any side effects yet. The only downside is that I have to take it with food four times a day, which can be a bit inconvenient.
4.7Patient Review
4/1/2014 So far, tindamax (tinidazole) has been great. I just have to make sure to eat something when I take it and drink lots of water, otherwise I get a metallic taste in my mouth.
4.7Patient Review
2/27/2013 I took two 500mg pills for five days and had no negative side effects, except for some very vivid dreams. The medication also did a great job of clearing up the odor by day two.
4.3Patient Review
8/24/2011 I was given a prescription for four 500mg doses to take at once for Trichomoniasis. The worst part of the experience was the awful metallic taste it left in my mouth. I took them right after dinner and before bed, slept like a baby and feel great. It seemed to clear up my problem and I actually woke up the next morning feeling well rested.
4Patient Review
10/26/2014 I'm currently on day two of a five-day tindamax regimen, and so far the only side effects I've experienced are a metallic taste in my mouth and a runny nose. That said, the medication does seem to be effective, as I noticed a difference after the first day. If you can get past the taste (eating some fruit snacks helps for me), then this is definitely worth trying.
3Patient Review
4/14/2012 This medication worked to clear up my infection, but it also came with some very severe and uncomfortable side effects. I would not recommend this to anyone.
3Patient Review
5/25/2013 I've been on this medication for three days now, taking 500mg twice a day. I haven't experienced any constipation, metallic taste, or vomiting, but I do feel horrible. I'm not sure if it's helping with my infection because I didn't know I had one until recently. However, I am starting to feel the yeast infection coming up. Additionally, this medication seems to interact poorly with my antidepressants and is making everything much worse. Therefore, I will be calling my doctor as soon as possible.
2.7Patient Review
6/15/2011 I had an unfortunate reaction to this treatment and it caused me to break out.
2.3Patient Review
1/15/2016 I took Tindamax for five days, twice a day as directed. By the first day, I had a metallic taste in my mouth that only got worse. I also started feeling nauseous on the second day and by the third, I was bedridden with a fever of 101 degrees. It was an awful experience and now I also have a white milky coating on my tongue - possibly thrush. I will never take this medication again.
Patient Q&A Section about tindamax
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How long does it take Tindamax to cure BV?
"Tinidazole is an effective treatment for trichomoniasis, with cure rates ranging from 46% to 91%."
Answered by AI
What is Tindamax used for?
"Tinidazole is used to treat infections caused by single-celled organisms (such as trichomoniasis, giardiasis, and amebiasis). It is also used to treat adult women with vaginal infections (bacterial vaginosis). Tinidazole belongs to the group of medicines called antiprotozoals."
Answered by AI
Is Tindamax stronger than Flagyl?
"The data suggests that tinidazole is more successful and can be tolerated better than metronidazole when given as a shorter course with only one daily dose for those with intestinal amoebiasis and amoebic liver abscess. Tinidazole is also successful in treating symptomatic giardiasis with only one dose."
Answered by AI
Is Tindamax the same as Flagyl?
"Tinidazole is a second-generation nitroimidazole, similar to metronidazole. It has a longer half-life than metronidazole, allowing for a shorter course of therapy."
Answered by AI