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What is Timentin
TicarcillinThe Generic name of this drug
Treatment SummaryClavulanic acid is a medication used in combination with other antibiotics, such as amoxicillin or ticarcillin, to fight antibiotic-resistant bacteria. Clavulanic acid comes from a bacteria known as Streptomyces clavuligerus and is often referred to as Augmentin, Co-Amoxiclav, or Clavulin when combined with amoxicillin. It prevents the degradation of other antibiotics by beta-lactamase enzymes, allowing them to be effective against a wider range of bacteria.
Timentinis the brand name
Timentin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Timentin
Ticarcillin
1990
4
Effectiveness
How Timentin Affects PatientsClavulanic acid helps antibiotics like amoxicillin to work better against bacteria. It does this by making the bacteria unable to break down the antibiotics, so that the antibiotics can fight the infection.
How Timentin works in the bodyClavulanic acid blocks the action of beta-lactamases, enzymes that break down certain antibiotics. By doing this, it allows antibiotics to remain effective in treating bacterial infections.
When to interrupt dosage
The advocated measure of Timentin is contingent upon the recognized health problem, such as Upper Respiratory Tract Infection, bacteroides fragilis and Staph Aureus Infection. The quantity of dosage is dependent on the technique of delivery which can be found in the table below.Condition
Dosage
Administration
Infection
1000.0 mg, , 3000.0 mg, 30000.0 mg, 30.0 mg/mL
, Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Warnings
Timentin has a total of six contraindications and should not be taken when experiencing the conditions in the table below.Timentin ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Common Timentin Drug Interactions
Drug Name
Risk Level
Description
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Ticarcillin.
Chlormadinone
Minor
The therapeutic efficacy of Chlormadinone can be decreased when used in combination with Ticarcillin.
Cloprostenol
Minor
The therapeutic efficacy of Cloprostenol can be decreased when used in combination with Ticarcillin.
Cyproterone acetate
Minor
The therapeutic efficacy of Cyproterone acetate can be decreased when used in combination with Ticarcillin.
Demegestone
Minor
The therapeutic efficacy of Demegestone can be decreased when used in combination with Ticarcillin.
Timentin Toxicity & Overdose RiskClavulanic acid is generally considered safe, with an LD50 of over 2000mg/kg in adult rodents. However, in pre-weaning rats lower doses (125mg/kg) can cause gastrointestinal distress and mortality. Taking too much of this drug in combination with amoxicillin may lead to changes in fluid and electrolyte balance, gastrointestinal symptoms, crystalluria, renal failure, and seizures. Treatment should focus on relieving symptoms and maintaining proper fluid and electrolyte balance. Hemodialysis may be used to remove the drug from the bloodstream.
Timentin Novel Uses: Which Conditions Have a Clinical Trial Featuring Timentin?
49 active clinical trials are being conducted to assess the potential of Timentin in treating Lower Respiratory Tract Infection (LRTI), Pseudomonas Aeruginosa and bacteroides fragilis.Condition
Clinical Trials
Trial Phases
Infection
9 Actively Recruiting
Phase 3, Not Applicable, Phase 1
Timentin Reviews: What are patients saying about Timentin?
3Patient Review
1/19/2008Patient Q&A Section about timentin
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the generic name for TIMENTIN?
"This is the name of the medication. Ticarcillin/clavulanate potassium is an antibiotic used to treat infections caused by bacteria. It is given by injection into a vein."
Answered by AI
What is TIMENTIN used for?
"Timentin is a prescription medicine used to treat the symptoms of various types of bacterial infections. These include infections of the blood (septicemia), lungs (lower respiratory infections), bones and joints (bone and joint infections), urinary tract (urinary tract infections), lining of the abdomen (intra-abdominal infections), and female reproductive organs (gynecologic infections). Timentin may be used alone or in combination with other medications."
Answered by AI
Is TIMENTIN still available?
"We are alerting you that GlaxoSmithKline has stopped making TIMENTIN® for the US."
Answered by AI
What type of drug is TIMENTIN?
"TIMENTIN consists of the semisynthetic antibiotic ticarcillin disodium and the β-lactamase inhibitor clavulanate potassium. It is for intravenous administration and is sterile and injectable."
Answered by AI