Nerve Grafting for Erectile Dysfunction After Prostate Cancer Surgery
(PRP-NR Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
A single arm prospective pilot trial evaluating the safety and the 1-year erectile recovery outcomes of patients undergoing a somatic to autonomic nerve grafting procedure for restoration of erectile function in patients who have lost erectile function following radical prostatectomy for prostate cancer. During this study a total of 10 patients who have persistent erectile dysfunction for more than 18 months post prostatectomy will undergo a post radical prostatectomy nerve restoration procedure (PRP-NR).
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It is best to discuss this with the trial coordinators or your doctor.
Is nerve grafting for erectile dysfunction after prostate cancer surgery safe?
How is the nerve grafting treatment for erectile dysfunction after prostate cancer surgery different from other treatments?
What data supports the effectiveness of the treatment for erectile dysfunction after prostate cancer surgery?
Research suggests that nerve grafting techniques, like using sural nerve grafts, have shown modest success in restoring erectile function after prostate surgery. Additionally, platelet-rich plasma (PRP) has shown promise in nerve regeneration, which could help improve erectile function after nerve injury.12346
Who Is on the Research Team?
Victor McPherson, MD
Principal Investigator
Jewish General Hospital
Are You a Good Fit for This Trial?
This trial is for men who've had prostate cancer surgery at least 18 months ago and are now experiencing persistent erectile dysfunction. It's a small study, aiming to include just 10 patients.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo the post radical prostatectomy nerve restoration procedure (PRP-NR)
Post-operative Monitoring
Participants are monitored for safety and recovery outcomes with questionnaires and clinical assessments
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Post radical prostatectomy nerve restoration procedure (PRP-NR)
Post radical prostatectomy nerve restoration procedure (PRP-NR) is already approved in United States, European Union for the following indications:
- Erectile dysfunction post radical prostatectomy
- Erectile dysfunction post radical prostatectomy
Find a Clinic Near You
Who Is Running the Clinical Trial?
Sir Mortimer B. Davis - Jewish General Hospital
Lead Sponsor