PrEP Awareness Program for HIV Prevention in Black Women

Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Duke University
Must be taking: PrEP
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to explore how effectively a program can increase awareness and use of PrEP, a medication that helps prevent HIV, among Black women. Researchers will pilot a program at a GYN residency clinic and use a social media campaign to determine if these efforts improve PrEP uptake. The trial suits Black cisgender women eligible for PrEP according to CDC guidelines. As an unphased study, this trial offers participants the opportunity to contribute to important research that could enhance HIV prevention strategies for Black women.

Do I need to stop my current medications for this trial?

The trial protocol does not specify whether you need to stop taking your current medications.

What prior data suggests that this program is safe for participants?

Research shows that the GYN Residency Training is safe for participants. Studies have found that after this training, most residents feel more confident and informed about prescribing PrEP, a medication that helps prevent HIV. This indicates that the training is well-received and does not cause harm.

For the Social Media Campaign, past efforts like PrEP4Love have successfully reached millions of people without any reported safety issues. These campaigns aim to raise awareness and do not involve taking any medication, so they are considered safe.

Both the training and the social media campaigns have been used before without causing problems. They focus on education and awareness, which are generally safe activities.12345

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores a fresh approach to increasing the use of PrEP (pre-exposure prophylaxis) for HIV prevention among Black women. Unlike traditional methods, this trial combines GYN residency training with a social media campaign to boost awareness and uptake of PrEP. The layered strategy aims to first strengthen the healthcare provider's role in prescribing PrEP and then leverage social media to engage Black women directly, fostering greater demand and awareness. This dual approach could potentially bridge gaps in current awareness and accessibility, making it a promising avenue for enhancing HIV prevention efforts in this community.

What evidence suggests that this trial's treatments could be effective for HIV prevention in Black women?

This trial will evaluate two separate interventions: GYN residency training and a social media campaign. Research has shown that training for GYN residents can improve their understanding of HIV prevention and increase the use of PrEP, a pill that helps prevent HIV. One study found that trainees knew more about PrEP after receiving education on it. Another study confirmed that PrEP training during residency is effective and important for increasing its use.

Regarding the social media campaign, studies have shown that well-executed campaigns can improve how often people start and continue using PrEP. For example, a community-driven campaign successfully connected with the target audience using engaging visuals and relatable spokespersons. Another study emphasized that such campaigns are vital for raising awareness and encouraging consistent use of PrEP in the community.12367

Who Is on the Research Team?

AC

Amy Corneli, MPH, PhD

Principal Investigator

Duke University

MC

Meredith Clement, MD

Principal Investigator

Louisiana State University Health Sciences Center

Are You a Good Fit for This Trial?

This trial is for LSU GYN residents and Black cisgender women who meet the CDC guidelines for PrEP, a medication that helps prevent HIV. It's designed to evaluate an initiative aimed at increasing PrEP use among these women in New Orleans.

Inclusion Criteria

LSU GYN residents
I am a Black cisgender woman eligible for PrEP according to CDC guidelines.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Pre-intervention

Collection of routine PrEP uptake data to establish a baseline for PrEP prescribing at the GYN residency clinics and local PrEP clinics

4 months

Implementation

Implementation of the combined-care model at the LSU GYN residency clinic at UMCNO and social media campaign in the NOLA area

10 months

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • GYN Residency Training
  • Social Media Campaign
Trial Overview The 'Start the Conversation' Initiative includes training for GYN residents and a social media campaign, both aiming to boost awareness and uptake of PrEP among eligible Black cisgender women to prevent HIV infection.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Start the Conversation PackageExperimental Treatment2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Duke University

Lead Sponsor

Trials
2,495
Recruited
5,912,000+

Louisiana State University Health Sciences Center in New Orleans

Collaborator

Trials
123
Recruited
42,400+

National Institute of Mental Health (NIMH)

Collaborator

Trials
3,007
Recruited
2,852,000+

Published Research Related to This Trial

Only 20.6% of women who use drugs (WWUD) in the U.S. are aware of HIV pre-exposure prophylaxis (PrEP), indicating a significant gap in knowledge about this preventive measure.
Among those who are aware of PrEP, 60.2% expressed willingness to use it, suggesting that increasing awareness could lead to higher uptake of this important HIV prevention strategy.
Suboptimal HIV Pre-exposure Prophylaxis Awareness and Willingness to Use Among Women Who Use Drugs in the United States: A Systematic Review and Meta-analysis.Zhang, C., McMahon, J., Simmons, J., et al.[2020]

Citations

Assessing Barriers in Obstetrics and Gynecology Trainee ...A significantly lower proportion of residents reported that they were comfortable with prescribing PrEP compared with the prior year (26.1% vs.
Integrating HIV Pre-Exposure Prophylaxis (PrEP) Education ...Our study revealed PrEP training during residency was effective per stated objectives and may be an important tool to increase PrEP delivery/uptake.
A Multi-Disciplinary University-Based HIV Prevention ...Knowledge increased significantly after the education program among trainees in OBGYN (2.3 vs 3.8, p < 0.001), pharmacy (1.4 vs 2.5, p = 0.012) and school of ...
Clinic-based interventions to increase preexposure ...This study aimed to increase preexposure prophylaxis counseling and uptake among cisgender women attending obstetrics and gynecology clinics.
Assessing Barriers in Obstetrics and Gynecology Trainee ...A significantly lower proportion of residents reported that they were comfortable with prescribing PrEP compared with the prior year (26.1% vs.
PrEP Training During Residency Increased Knowledge of ...Residents grew more knowledgeable and more comfortable with using pre-exposure prophylaxis (PrEP) drugs for prevention against HIV after ...
7.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/37015803/
Training obstetrician gynaecologists in HIV PrEP (pre- ...After the trainings, the majority of participants reported feeling 'comfortable' or 'very comfortable' in determining candidacy for PrEP and prescribing PrEP ...
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