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What is Taclonex
CalcipotriolThe Generic name of this drug
Treatment SummaryBetamethasone is a steroid medication that helps reduce inflammation and suppress the immune system. It can be applied directly to the skin to treat inflammatory skin conditions like eczema, and given intravenously to treat autoimmune diseases. The drug works by blocking the production of certain hormones that trigger inflammation.
Calcipotrieneis the brand name
Taclonex Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Calcipotriene
Calcipotriol
1996
56
Effectiveness
How Taclonex Affects PatientsCorticosteroids are a type of medicine that reduce inflammation and inhibit pro-inflammatory signals. Depending on the patient, a dose much larger than normal may be prescribed. People who need to take a corticosteroid for a long time should be aware of the risk of the body not producing hormones correctly and the increased likelihood of getting infections.
How Taclonex works in the bodyGlucocorticoids like betamethasone work by reducing inflammation and encouraging anti-inflammatory reactions. They block molecules that trigger inflammatory responses, such as NF-Kappa B and other transcription factors. They also stop the formation of arachidonic acid derivatives. Betamethasone works in two ways: it either activates receptors to start a slower, anti-inflammatory process, or it uses existing receptors to quickly reduce current inflammation.
When to interrupt dosage
The quantity of Taclonex is contingent upon the diagnosed condition, including Ankylosing Spondylitis, Adrenal cortical hypofunctions and Post Surgical Ocular Inflammation. The amount also changes depending on the mode of delivery (e.g. Topical or Solution - Oral) showcased in the table beneath.Condition
Dosage
Administration
Psoriasis
, 0.05 mg/mL, 0.00005 mg/mg
, Topical, Solution, Solution - Topical, Cream, Cream - Topical, Ointment, Ointment - Topical, Spray, metered, Spray, metered - Topical, Suspension, Suspension - Topical, Gel - Topical, Gel, Aerosol, foam, Aerosol, foam - Topical, Kit, Kit - Topical
Psoriasis Vulgaris
, 0.05 mg/mL, 0.00005 mg/mg
, Topical, Solution, Solution - Topical, Cream, Cream - Topical, Ointment, Ointment - Topical, Spray, metered, Spray, metered - Topical, Suspension, Suspension - Topical, Gel - Topical, Gel, Aerosol, foam, Aerosol, foam - Topical, Kit, Kit - Topical
Warnings
Taclonex has one contraindication, so it should not be utilized when experiencing the conditions enumerated in the following table.Taclonex ContraindicationsCondition
Risk Level
Notes
Hypercalcemia
Do Not Combine
vitamin D intoxication
Do Not Combine
use in the face
Do Not Combine
Common Taclonex Drug Interactions
Drug Name
Risk Level
Description
Calcium
Moderate
The risk or severity of adverse effects can be increased when Calcipotriol is combined with Calcium.
Calcium Phosphate
Moderate
The risk or severity of adverse effects can be increased when Calcipotriol is combined with Calcium Phosphate.
Calcium acetate
Moderate
The risk or severity of adverse effects can be increased when Calcipotriol is combined with Calcium acetate.
Calcium carbonate
Moderate
The risk or severity of adverse effects can be increased when Calcipotriol is combined with Calcium carbonate.
Calcium cation
Moderate
The risk or severity of adverse effects can be increased when Calcipotriol is combined with Calcium cation.
Taclonex Toxicity & Overdose RiskTaking high amounts of glucocorticoids for a long period of time can cause cataracts, glaucoma, high blood pressure, water retention, high cholesterol, stomach ulcers, pancreatitis, muscle weakness, mood changes, psychosis, thinning skin, allergies, acne, excessive hair growth, reduced immunity, diabetes, low calcium and phosphorus levels, acid buildup in the body, slowed growth in children, and decreased hormone production in the adrenal glands. Treatment for overdose includes reducing the dose or stopping the steroid, as well as providing symptom relief and supportive care.
Taclonex Novel Uses: Which Conditions Have a Clinical Trial Featuring Taclonex?
249 active investigations are assessing the potential of Taclonex to treat Eye Infection, Alopecia Areata (AA) and Verrucous Lichen Planus (LP).Condition
Clinical Trials
Trial Phases
Psoriasis Vulgaris
22 Actively Recruiting
Early Phase 1, Phase 4, Phase 3, Not Applicable, Phase 2
Psoriasis
0 Actively Recruiting
Taclonex Reviews: What are patients saying about Taclonex?
5Patient Review
6/21/2011 This medication quickly and effectively reduced the severity of my flare-up, and I only had to pay $0 thanks to a coupon from my dermatologist.
5Patient Review
8/13/2010 This treatment really helped me. I'm grateful for modern medicine.
5Patient Review
7/6/2012 I've been using this for fifteen years and it's by far the most effective treatment I've tried. Not to mention, it's really easy to use!
4.3Patient Review
3/14/2011 Worked great at first, but then I started getting blisters in certain spots.
4Patient Review
10/14/2011 This didn't help me at all.
3.3Patient Review
2/14/2011 After trying cortisone and other topical treatments without success, I was given a sample of taclonex by my dermatologist. This completely cleared up my issue within three weeks. Now, if I get the occasional spot, I use it a couple times a month. Even with a coupon, though, my copay is still $55.
3Patient Review
6/28/2015 This gel form of the drug is just as effective as anything else I've used in the past. The main issue I have is that it's difficult to tell how much is actually coming out and if any is being wasted. With liquid drugs, it's easier to feel them come out.
3Patient Review
7/14/2014 I've been using this medication for two months now. While it has helped to stop the flaking and itching, my hair has become very greasy as a result. It's also quite expensive; even with insurance, it cost me $60.
3Patient Review
3/15/20102.7Patient Review
7/29/2013 I've been losing my hair and having my period continuously since I started Taclonex. That being said, my rash has mostly disappeared but I still have faded red blotches and flaky/dry skin.
2.7Patient Review
10/26/2012 After trying a bunch of different treatments that didn't work or had nasty side effects, I finally found one that worked for me. Taclonex is expensive, but it's worth it if you're struggling with plaque psoriasis.
1.7Patient Review
3/17/20101Patient Review
6/23/2016 A few years ago, I used this treatment on my feet. It did help my feet, but now I have developed painful red patches on my palms and fingers which peel. I believe that this product has permanently thinned my skin, and I am considering legal action. Do not use it.
1Patient Review
2/3/2016 I am blown away by how expensive this product is. I called customer service to confirm the price, and it took over 35 minutes for anyone to answer the phone. Very disappointing.
1Patient Review
3/23/2017 The cost of this medication is outrageous. Even with insurance, I was expecting to pay a lot less than I did. The discount card didn't help as much as I thought it would either.
1Patient Review
4/7/2013 I used taclonex for seven days and got an awful, itchy rash all over my back and stomach. A biopsy showed that the drug was the cause.
1Patient Review
6/27/2014 The price of this prescription at Costco was absurdly high. Over $1400!!! I walked away and refuse to pay that much.
1Patient Review
10/13/2011 Taclonex was a total lifesaver for my psoriasis. I had tried another cream previously with zero success, but this worked within a month.
Patient Q&A Section about taclonex
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Taclonex a steroid?
"Taclonex contains a combination of betamethasone and calcipotriene. Betamethasone is a steroid that prevents the release of substances in the body that cause inflammation. Calcipotriene is a form of vitamin d."
Answered by AI
What is the generic drug for Taclonex?
"Sandoz is marketing the ointment in 60 gram and 100 gram tubes, the same strengths that are marketed as Taclonex® Ointment."
Answered by AI
What is Taclonex drug used for?
"This medication is used to treat psoriasis. It helps to reduce the redness, thickness, and scaling of the skin. Healthy skin lowers your risk of infection and protects you against the environment."
Answered by AI
How long does it take Taclonex to work?
"If your condition does not improve after 2 weeks, or gets worse, tell your doctor."
Answered by AI