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What is Skelaxin
MetaxaloneThe Generic name of this drug
Treatment SummaryMetaxalone is a medication used to relieve muscle pain, spasms, and strains. It works by temporarily depressing the central nervous system. Metaxalone is sold under the brand name Skelaxin® and comes in an 800 mg scored tablet. This drug has few side effects and is generally safe for most people to use.
Skelaxinis the brand name
Skelaxin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Skelaxin
Metaxalone
1962
134
Approved as Treatment by the FDA
Metaxalone, otherwise called Skelaxin, is approved by the FDA for 4 uses which include Pain and Musculoskeletal Disorders .Pain
Helps manage Pain
Musculoskeletal Disorders
Helps manage Musculoskeletal Disorders
Chronic Pain
Helps manage Pain
Musculoskeletal Diseases
Helps manage Musculoskeletal Disorders
Effectiveness
How Skelaxin Affects PatientsMetaxalone is a drug that helps relieve pain and discomfort from muscle issues. It works by helping people rest, and can also be used in conjunction with physical therapy. The exact way it works is not known, but may be related to its calming effects. Metaxalone does not work by directly relaxing tense muscles.
How Skelaxin works in the bodyWe are not sure how metaxalone works, but it likely works by calming the central nervous system.
When to interrupt dosage
The proposed dose of Skelaxin is contingent upon the perceived sickness. The amount of dosage is dependent on the method of delivery listed in the table beneath.Condition
Dosage
Administration
Musculoskeletal Diseases
800.0 mg, , 400.0 mg, 640.0 mg
, Oral, Tablet - Oral, Tablet, Kit
Chronic Pain
800.0 mg, , 400.0 mg, 640.0 mg
, Oral, Tablet - Oral, Tablet, Kit
Warnings
There are 20 known major drug interactions with Skelaxin.Common Skelaxin Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Metaxalone may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Ethanol
Major
Metaxalone may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Methylene blue
Major
Metaxalone may increase the serotonergic activities of Methylene blue.
Mirtazapine
Major
Metaxalone may increase the serotonergic activities of Mirtazapine.
Oliceridine
Major
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Metaxalone is combined with Oliceridine.
Skelaxin Toxicity & Overdose RiskTests on rats and mice have found that the toxic dose of the drug is 775mg/kg and 1690mg/kg respectively. As the dosage increases, symptoms such as sedation, hypnosis, and eventually difficulty breathing were observed. Dogs showed signs of nausea after 15-30 minutes of being given the drug. Other common side effects of overdose include vomiting, drowsiness, dizziness, headaches, and irritability.
Skelaxin Novel Uses: Which Conditions Have a Clinical Trial Featuring Skelaxin?
177 active clinical trials are presently being conducted to evaluate the potential of Skelaxin in treating Musculoskeletal Disorders.Condition
Clinical Trials
Trial Phases
Musculoskeletal Diseases
2 Actively Recruiting
Not Applicable
Chronic Pain
144 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 4, Phase 3, Early Phase 1
Skelaxin Reviews: What are patients saying about Skelaxin?
5Patient Review
2/16/2014 This medication quickly and effectively alleviated my muscle cramps. I was previously taking Flexeril, which worked well for me until it was discontinued.
5Patient Review
5/30/2014 I started taking this yesterday and it has already done wonders for my muscle spasms. I was in a lot of pain yesterday, but today I can walk and climb stairs with only some residual pain. So far there haven't been any negative side effects like upset stomach, which is great.
5Patient Review
1/30/2015 I'm glad I found this treatment. It's been really helpful, even though it can be tough to keep up with the recommended dosage schedule.
5Patient Review
7/13/2015 Skelaxin was a huge help for me after I hurt my neck and shoulders. The pain was constant, but after a few weeks on this medication, it got much better. I could actually function again without being in constant pain.
5Patient Review
6/19/2014 Skelaxin is a really great relaxer, and it's helped me a lot. However, I find it to be quite expensive. Are there any other options out there that are cheaper but just as effective?
Patient Q&A Section about skelaxin
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Skelaxin a strong muscle relaxer?
"No, metaxalone does not relieve pain from other sources such as inflammatory or nerve pain."
Answered by AI
Is Skelaxin an anti inflammatory?
"Metaxalone is a skeletal muscle relaxant that is classified as a non-steroidal anti-inflammatory drug (NSAID) and an analgesic (painkiller)."
Answered by AI
What is Skelaxin 800 mg prescribed for?
"Skelaxin is a prescription medication used to treat the symptoms of musculoskeletal pain. Skelaxin can be used alone or with other medications. Skelaxin is a type of drug called a Skeletal Muscle Relaxant."
Answered by AI
Is Skelaxin the same as Flexeril?
"Both Skelaxin and Flexeril are used to treat painful muscle spasms and have similar side effects including drowsiness, dizziness, headache, nausea or stomach upset/pain."
Answered by AI
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