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What is Secuado
AsenapineThe Generic name of this drug
Treatment SummaryAsenapine is an antipsychotic medication used to treat schizophrenia and acute mania associated with bipolar disorder. It is taken under the tongue, and is also approved off-label for severe post-traumatic stress disorder nightmares in soldiers. Asenapine was developed by the company Schering-Plough and was approved by the FDA in 2009.
Saphrisis the brand name
Secuado Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Saphris
Asenapine
2009
35
Approved as Treatment by the FDA
Asenapine, also called Saphris, is approved by the FDA for 4 uses such as Schizophrenia and Bipolar Disorder .Schizophrenia
Helps manage Schizophrenia
Bipolar Disorder
Helps manage Mixed manic depressive episode
Acute Coryza
Helps manage acute Manic episode
Bipolar Disorder
Helps manage Bipolar 1 Disorder
Effectiveness
How Secuado Affects PatientsAsenapine is a drug that helps treat mental health conditions by blocking the activity of serotonin, dopamine, noradrenaline, and histamine in the brain. It is known to cause sedation, but has a lower chance of causing involuntary movements than other antipsychotics. It does not interact with the same receptors as anticholinergic drugs, meaning it will not cause side effects like dry mouth or constipation. Compared to other antipsychotics, it is more effective at blocking serotonin, dopamine, noradrenaline, and histamine but is less effective at blocking 5-HT1A and 5-HT1B
How Secuado works in the bodyAsenapine is a medication used to treat schizophrenia. It works by blocking the activity of certain natural substances in the brain, including serotonin and dopamine. This helps to increase the amount of dopamine and acetylcholine in the brain, which can help improve cognitive function and reduce negative symptoms associated with schizophrenia.
When to interrupt dosage
The recommended amount of Secuado is contingent upon the diagnosed affliction, for instance Bipolar Disorder, Schizophrenia and Acute Coryza. The dose is contingent upon the method of administering, detailed in the table below.Condition
Dosage
Administration
Bipolar Disorder
5.0 mg, , 10.0 mg, 2.5 mg, 0.57 mg/hour, 0.38 mg/hour, 0.76 mg/hour
, Sublingual, Tablet, Tablet - Sublingual, Film, extended release - Transdermal, Film, extended release, Transdermal
maintenance therapy
5.0 mg, , 10.0 mg, 2.5 mg, 0.57 mg/hour, 0.38 mg/hour, 0.76 mg/hour
, Sublingual, Tablet, Tablet - Sublingual, Film, extended release - Transdermal, Film, extended release, Transdermal
Acute Coryza
5.0 mg, , 10.0 mg, 2.5 mg, 0.57 mg/hour, 0.38 mg/hour, 0.76 mg/hour
, Sublingual, Tablet, Tablet - Sublingual, Film, extended release - Transdermal, Film, extended release, Transdermal
Bipolar Disorder
5.0 mg, , 10.0 mg, 2.5 mg, 0.57 mg/hour, 0.38 mg/hour, 0.76 mg/hour
, Sublingual, Tablet, Tablet - Sublingual, Film, extended release - Transdermal, Film, extended release, Transdermal
Schizophrenia
5.0 mg, , 10.0 mg, 2.5 mg, 0.57 mg/hour, 0.38 mg/hour, 0.76 mg/hour
, Sublingual, Tablet, Tablet - Sublingual, Film, extended release - Transdermal, Film, extended release, Transdermal
Warnings
Secuado ContraindicationsCondition
Risk Level
Notes
Severe Hepatic Impairment
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Asenapine may interact with Pulse Frequency
Common Secuado Drug Interactions
Drug Name
Risk Level
Description
Alfuzosin
Major
Asenapine may increase the hypotensive activities of Alfuzosin.
Amisulpride
Major
Asenapine may increase the antipsychotic activities of Amisulpride.
Aripiprazole lauroxil
Major
Asenapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole lauroxil.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Asenapine is combined with Artemether.
Azelastine
Major
Asenapine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Secuado Novel Uses: Which Conditions Have a Clinical Trial Featuring Secuado?
171 active trials are currently underway to investigate the potential of Secuado in providing relief from Schizophrenia, Bipolar Disorder and Acute Coryza.Condition
Clinical Trials
Trial Phases
Schizophrenia
176 Actively Recruiting
Not Applicable, Phase 3, Phase 2, Early Phase 1, Phase 4, Phase 1
maintenance therapy
0 Actively Recruiting
Bipolar Disorder
1 Actively Recruiting
Phase 4
Bipolar Disorder
0 Actively Recruiting
Acute Coryza
1 Actively Recruiting
Not Applicable
Patient Q&A Section about secuado
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What antipsychotic medication is available in a transdermal patch?
"A transdermal patch is a formulation of the atypical antipsychotic asenapine, which is sold under the brand name Secuado and manufactured by Noven Pharmaceuticals. The patch is applied once daily to provide equal concentrations of the medication over a 24-hour period."
Answered by AI
Is Secuado an antipsychotic?
"Secuado is a prescription antipsychotic medication used to treat the symptoms of schizophrenia in adults. It is unknown if Secuado is safe and effective for use in children."
Answered by AI
Who makes Secuado?
"In March 2020, Noven launched SECUADO, an atypical antipsychotic medication used to treat adults with schizophrenia, in the form of a transdermal system."
Answered by AI
What is Secuado used for?
"SECUADO is a transdermal system (patch) you apply to your skin which is used to treat adults with schizophrenia. Its safety and effectiveness has not been determined in children less than 18 years of age with schizophrenia."
Answered by AI