Pharmacist Intervention for Smoking Cessation

Overseen By Shelby L Francis, PhD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: University of Iowa

Disqualifiers: Non-English speakers, Unable to consent

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 7

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests whether talking with a pharmacist can help smokers quit. It targets current smokers undergoing regular lung cancer screenings. Participants will either have several conversations with a pharmacist over a few months or complete surveys. The goal is to determine if the pharmacist's advice aids smoking cessation more effectively than surveys alone. Current smokers in a lung cancer screening program may be suitable candidates for this study. As an unphased trial, this study provides a unique opportunity to contribute to research that could enhance smoking cessation support.

Do I need to stop taking my current medications to join the trial?

The trial information does not specify whether you need to stop taking your current medications. It focuses on smoking cessation and does not mention any medication restrictions.

What prior data suggests that this pharmacist intervention is safe for smoking cessation?

Research has shown that assistance from pharmacists to quit smoking is generally safe and well-received. In one study, a pharmacist-led service changed people's attitudes about quitting. Specifically, 33 participants chose to use nicotine patches or gum, and 11 successfully quit smoking. Another study demonstrated that 59% of participants quit smoking after receiving help from a pharmacist.

These results suggest that consulting a pharmacist can be a safe and effective way to quit smoking. No reports of serious side effects have emerged from discussing quitting with a pharmacist, indicating that this approach is likely safe for those considering joining the trial. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about the pharmacist intervention for smoking cessation because it introduces a new support system that directly involves pharmacists in helping individuals quit smoking. Unlike traditional treatments, which often include nicotine replacement therapies or prescription medications, this approach leverages pharmacists' accessibility and expertise to provide personalized counseling and follow-up support. This method can potentially enhance motivation and adherence to quit plans, offering a more integrated and supportive experience for those looking to kick the habit.

What evidence suggests that this pharmacist intervention is effective for smoking cessation?

Research has shown that help from pharmacists can greatly assist people in quitting smoking. In one study, 54.3% of people who worked with a pharmacist quit smoking after a year, compared to 37.1% who did not have this support. Another study found that 28% of those who received help from a pharmacist quit smoking within six months, while only 11.8% of those who received regular care did. These results suggest that regular meetings with a pharmacist can improve the chances of quitting smoking successfully. Participants in this trial will join either the Pharmacist Intervention Group or the Control Group to further evaluate the effectiveness of pharmacist support in smoking cessation. The evidence supports the idea that pharmacist help can be a powerful tool for quitting smoking. ^{1 5 6 7 8}

Who Is on the Research Team?

Jacob E Simmering, PhD

Principal Investigator

University of Iowa

Are You a Good Fit for This Trial?

This trial is for current smokers enrolled in the Lung Cancer Screening Program. It's designed to see if talking with a pharmacist over the phone can help them quit smoking, especially those getting low-radiation chest CT scans.

Inclusion Criteria

I currently smoke.

I am currently enrolled in a Lung Cancer Screening Program.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants in the intervention group complete a baseline survey and have phone calls with a pharmacist at baseline, 2, 4, 6, 8, 10, and 12 weeks

12 weeks

7 phone calls

Control

Participants in the control group complete a baseline survey and an exit survey

12 weeks

Follow-up

Participants are monitored for smoking cessation success and use of nicotine replacement therapies

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Pharmacist Intervention

Trial Overview The study tests a remote pharmacist intervention where participants receive regular phone calls from a pharmacist to discuss quitting smoking. The control group only completes surveys without additional support.

How Is the Trial Designed?

Group I: Pharmacist Intervention Group Experimental Treatment 1 Intervention

Group II: Control Group Active Control 1 Intervention

Who Is Running the Clinical Trial?

University of Iowa

Lead Sponsor

Trials

486

Recruited

934,000+

Citations

1. sciencedirect.com sciencedirect.com/science/article/pii/S1551741123003686

Smoking cessation intervention in the community pharmacy At 12 months, 54.3% and 37.1% patients from the intervention and the control groups reported smoking cessation, respectively. The difference in probability of ...

2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC6822095/

Community pharmacy personnel interventions for smoking ... We pooled six studies of 1614 participants and detected a benefit of more intensive behavioural smoking cessation interventions delivered by ...

3. bmcpublichealth.biomedcentral.com bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-017-4103-4

Effectiveness of a pharmacist-delivered smoking cessation ... At 6 months, the biochemically confirmed smoking cessation quit rate was 28% in the face to face group and 11.8% in the standard care group (p < ...

4. accpjournals.onlinelibrary.wiley.com accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1864

Pharmacist-Led Smoking Cessation in Pulmonary Clinic Overall, patients managed by the pharmacist achieved significantly higher cessation rates at 12 months and significantly higher rates of ...

5. tobaccoinduceddiseases.org tobaccoinduceddiseases.org/A-community-based-pharmacist-led-smoking-cessation-nprogram-before-elective-total,126405,0,2.html

A community-based pharmacist-led smoking cessation ... Smoking cessation, the primary outcome, was ascertained independently of participating pharmacists at 6 weeks post-operative using exhaled CO ...

6. sciencedirect.com sciencedirect.com/science/article/pii/S294996902500003X

Impact of a pharmacist-led smoking cessation service on ... A pharmacist-led service positively affected attitudes toward smoking, with 33 participants agreeing to use NRT and 11 self-reporting smoking cessation.

7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC10603824/

Pharmacist prescriber smoking cessation intervention during ... The questionnaire was completed by 85 clients with 59% reporting they had quit. Eleven clients and seven out of eight pharmacists were ...

8. clinicaltrials.gov clinicaltrials.gov/study/NCT06943287

Pharmacist Intervention to Improve Smoking Cessation | ... A phase of research to describe clinical trials that focus on the safety of a drug. They are usually conducted with healthy volunteers, and the goal is to ...