SLN Biopsy for Eyelid Melanoma

Age: 18+

Sex: Any

Trial Phase: Phase 1

Sponsor: M.D. Anderson Cancer Center

Disqualifiers: Pregnancy, Nursing

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

38 Participants Needed

Trial Summary

What is the purpose of this trial?

The goal of this clinical research study is to find the sentinel lymph node (SLN) (s) and biopsy it (them) to see if the patient has small or low volume metastatic disease that would otherwise have been missed.

Research Team

Bita Esmaeli

Principal Investigator

M.D. Anderson Cancer Center

Eligibility Criteria

This trial is for adults with a specific eye cancer called conjunctival/eyelid melanoma. They must have no signs of the cancer spreading on ultrasound, chest X-ray, liver tests, or head and neck scans. Participants need to give written consent and can't be pregnant or nursing.

Inclusion Criteria

I have a confirmed melanoma of the eye or eyelid that is thick or shows signs of severe growth.

You need to have a recent ultrasound showing that the lymph nodes in your body are not swollen.

Your chest X-ray, liver enzymes, and head and neck CT or MRI show no signs of cancer spreading to other parts of your body.

Exclusion Criteria

Pregnant or nursing females.

Treatment Details

Interventions

• Sentinel Lymph Node Mapping and Biopsy

Trial Overview The study aims to locate and biopsy the sentinel lymph node(s) in patients with eyelid or conjunctival melanoma to detect any early spread of cancer that might not be otherwise noticed.

Participant Groups

Group I: Sentinel Lymph Node (SLN) Biopsy Experimental Treatment 1 Intervention

Intraoperative lymphatic mapping, then biopsy/removal of the conjunctiva/eyelid tumor.

Who Is Running the Clinical Trial?

M.D. Anderson Cancer Center

Lead Sponsor

Trials

3,107

Recruited

1,813,000+