Retin-A

mottled hyperpigmentation, Alopecia, Hyperpigmentation + 14 more

Treatment

2 FDA approvals

16 Active Studies for Retin-A

What is Retin-A

Tretinoin

The Generic name of this drug

Treatment Summary

Tretinoin, also known as ATRA, is a form of Vitamin A. It is used to regulate cell growth and treat skin conditions like acne and photo damage. It is also used to treat keratinization disorders such as ichthyosis and keratosis follicularis. In addition, it is an important anti-cancer drug used in the treatment of acute promyelocytic leukemia (APL).

Tretinoin Cream

is the brand name

image of different drug pills on a surface

Retin-A Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Tretinoin Cream

Tretinoin

1973

185

Approved as Treatment by the FDA

Tretinoin, also known as Tretinoin Cream, is approved by the FDA for 2 uses including Alopecia and Alopecia .

Alopecia

Used to treat Alopecia in combination with Minoxidil

Alopecia

Used to treat Alopecia in combination with Minoxidil

Effectiveness

How Retin-A Affects Patients

Tretinoin, also known as ATRA (all-trans-retinoic acid), is a form of vitamin A. It helps control how cells reproduce, grow, and develop. It is used to treat acne, sun-damaged skin, and certain skin conditions like ichthyosis or keratosis follicularis. It can also be used as an anti-cancer drug to treat a type of blood cancer called acute promyelocytic leukemia (APL).

How Retin-A works in the body

Tretinoin works by affecting the retinoic acid receptors in the body. It helps reduce acne by increasing cell turnover in the follicles, making it easier for comedones to be shed. It also has anti-cancer effects, as it can cause cells from acute promyelocytic leukemia and squamous cell cancers to mature. The exact mechanism of action for these cancer fighting effects is unknown.

When to interrupt dosage

The proposed dosage of Retin-A is contingent upon the characterized condition, including Alopecia, Chloasma and Chloasma. The amount of dosage differs, as per the method of administration delineated in the table beneath.

Condition

Dosage

Administration

Fine Wrinkles

, 0.0005 mg/mg, 0.001 mg/mg, 0.00025 mg/mg, 0.000375 mg/mg, 0.00075 mg/mg, 0.0001 mg/mg, 0.0002 mg/mg, 0.00005 mg/mg, 0.000025 mg/mg, 0.0004 mg/mg, 0.4 mL/mg, 0.001 mL/mg, 10.0 mg, 0.00001 mg/mg, 0.1 %, 0.025 %, 0.05 %, 0.01 %, 0.04 %, 0.00004 mg/mg, 0.0008 mg/mg, 0.1 mg/mL, 0.0006 mg/mg, 2.5 mg/mg, 0.5 mg/mL, 0.0025 mg/mg, 0.000015 mg/mg, 0.0000075 mg/mg

, Gel, Gel - Topical, Topical, Cream, Cream - Topical, Kit, Oral, Capsule - Oral, Capsule, Liquid, Liquid - Topical, Solution, Solution - Topical, Capsule, liquid filled, Capsule, liquid filled - Oral, Emulsion, Lotion, Lotion - Topical, Emulsion - Topical, Kit - Topical

mottled hyperpigmentation

, 0.0005 mg/mg, 0.001 mg/mg, 0.00025 mg/mg, 0.000375 mg/mg, 0.00075 mg/mg, 0.0001 mg/mg, 0.0002 mg/mg, 0.00005 mg/mg, 0.000025 mg/mg, 0.0004 mg/mg, 0.4 mL/mg, 0.001 mL/mg, 10.0 mg, 0.00001 mg/mg, 0.1 %, 0.025 %, 0.05 %, 0.01 %, 0.04 %, 0.00004 mg/mg, 0.0008 mg/mg, 0.1 mg/mL, 0.0006 mg/mg, 2.5 mg/mg, 0.5 mg/mL, 0.0025 mg/mg, 0.000015 mg/mg, 0.0000075 mg/mg

, Gel, Gel - Topical, Topical, Cream, Cream - Topical, Kit, Oral, Capsule - Oral, Capsule, Liquid, Liquid - Topical, Solution, Solution - Topical, Capsule, liquid filled, Capsule, liquid filled - Oral, Emulsion, Lotion, Lotion - Topical, Emulsion - Topical, Kit - Topical

Alopecia

, 0.0005 mg/mg, 0.001 mg/mg, 0.00025 mg/mg, 0.000375 mg/mg, 0.00075 mg/mg, 0.0001 mg/mg, 0.0002 mg/mg, 0.00005 mg/mg, 0.000025 mg/mg, 0.0004 mg/mg, 0.4 mL/mg, 0.001 mL/mg, 10.0 mg, 0.00001 mg/mg, 0.1 %, 0.025 %, 0.05 %, 0.01 %, 0.04 %, 0.00004 mg/mg, 0.0008 mg/mg, 0.1 mg/mL, 0.0006 mg/mg, 2.5 mg/mg, 0.5 mg/mL, 0.0025 mg/mg, 0.000015 mg/mg, 0.0000075 mg/mg

, Gel, Gel - Topical, Topical, Cream, Cream - Topical, Kit, Oral, Capsule - Oral, Capsule, Liquid, Liquid - Topical, Solution, Solution - Topical, Capsule, liquid filled, Capsule, liquid filled - Oral, Emulsion, Lotion, Lotion - Topical, Emulsion - Topical, Kit - Topical

Hyperpigmentation

, 0.0005 mg/mg, 0.001 mg/mg, 0.00025 mg/mg, 0.000375 mg/mg, 0.00075 mg/mg, 0.0001 mg/mg, 0.0002 mg/mg, 0.00005 mg/mg, 0.000025 mg/mg, 0.0004 mg/mg, 0.4 mL/mg, 0.001 mL/mg, 10.0 mg, 0.00001 mg/mg, 0.1 %, 0.025 %, 0.05 %, 0.01 %, 0.04 %, 0.00004 mg/mg, 0.0008 mg/mg, 0.1 mg/mL, 0.0006 mg/mg, 2.5 mg/mg, 0.5 mg/mL, 0.0025 mg/mg, 0.000015 mg/mg, 0.0000075 mg/mg

, Gel, Gel - Topical, Topical, Cream, Cream - Topical, Kit, Oral, Capsule - Oral, Capsule, Liquid, Liquid - Topical, Solution, Solution - Topical, Capsule, liquid filled, Capsule, liquid filled - Oral, Emulsion, Lotion, Lotion - Topical, Emulsion - Topical, Kit - Topical

tactile roughness of facial skin

, 0.0005 mg/mg, 0.001 mg/mg, 0.00025 mg/mg, 0.000375 mg/mg, 0.00075 mg/mg, 0.0001 mg/mg, 0.0002 mg/mg, 0.00005 mg/mg, 0.000025 mg/mg, 0.0004 mg/mg, 0.4 mL/mg, 0.001 mL/mg, 10.0 mg, 0.00001 mg/mg, 0.1 %, 0.025 %, 0.05 %, 0.01 %, 0.04 %, 0.00004 mg/mg, 0.0008 mg/mg, 0.1 mg/mL, 0.0006 mg/mg, 2.5 mg/mg, 0.5 mg/mL, 0.0025 mg/mg, 0.000015 mg/mg, 0.0000075 mg/mg

, Gel, Gel - Topical, Topical, Cream, Cream - Topical, Kit, Oral, Capsule - Oral, Capsule, Liquid, Liquid - Topical, Solution, Solution - Topical, Capsule, liquid filled, Capsule, liquid filled - Oral, Emulsion, Lotion, Lotion - Topical, Emulsion - Topical, Kit - Topical

severe, recalcitrant Cystic acne

, 0.0005 mg/mg, 0.001 mg/mg, 0.00025 mg/mg, 0.000375 mg/mg, 0.00075 mg/mg, 0.0001 mg/mg, 0.0002 mg/mg, 0.00005 mg/mg, 0.000025 mg/mg, 0.0004 mg/mg, 0.4 mL/mg, 0.001 mL/mg, 10.0 mg, 0.00001 mg/mg, 0.1 %, 0.025 %, 0.05 %, 0.01 %, 0.04 %, 0.00004 mg/mg, 0.0008 mg/mg, 0.1 mg/mL, 0.0006 mg/mg, 2.5 mg/mg, 0.5 mg/mL, 0.0025 mg/mg, 0.000015 mg/mg, 0.0000075 mg/mg

, Gel, Gel - Topical, Topical, Cream, Cream - Topical, Kit, Oral, Capsule - Oral, Capsule, Liquid, Liquid - Topical, Solution, Solution - Topical, Capsule, liquid filled, Capsule, liquid filled - Oral, Emulsion, Lotion, Lotion - Topical, Emulsion - Topical, Kit - Topical

Acute Promyelocytic Leukemia

, 0.0005 mg/mg, 0.001 mg/mg, 0.00025 mg/mg, 0.000375 mg/mg, 0.00075 mg/mg, 0.0001 mg/mg, 0.0002 mg/mg, 0.00005 mg/mg, 0.000025 mg/mg, 0.0004 mg/mg, 0.4 mL/mg, 0.001 mL/mg, 10.0 mg, 0.00001 mg/mg, 0.1 %, 0.025 %, 0.05 %, 0.01 %, 0.04 %, 0.00004 mg/mg, 0.0008 mg/mg, 0.1 mg/mL, 0.0006 mg/mg, 2.5 mg/mg, 0.5 mg/mL, 0.0025 mg/mg, 0.000015 mg/mg, 0.0000075 mg/mg

, Gel, Gel - Topical, Topical, Cream, Cream - Topical, Kit, Oral, Capsule - Oral, Capsule, Liquid, Liquid - Topical, Solution, Solution - Topical, Capsule, liquid filled, Capsule, liquid filled - Oral, Emulsion, Lotion, Lotion - Topical, Emulsion - Topical, Kit - Topical

Chloasma

, 0.0005 mg/mg, 0.001 mg/mg, 0.00025 mg/mg, 0.000375 mg/mg, 0.00075 mg/mg, 0.0001 mg/mg, 0.0002 mg/mg, 0.00005 mg/mg, 0.000025 mg/mg, 0.0004 mg/mg, 0.4 mL/mg, 0.001 mL/mg, 10.0 mg, 0.00001 mg/mg, 0.1 %, 0.025 %, 0.05 %, 0.01 %, 0.04 %, 0.00004 mg/mg, 0.0008 mg/mg, 0.1 mg/mL, 0.0006 mg/mg, 2.5 mg/mg, 0.5 mg/mL, 0.0025 mg/mg, 0.000015 mg/mg, 0.0000075 mg/mg

, Gel, Gel - Topical, Topical, Cream, Cream - Topical, Kit, Oral, Capsule - Oral, Capsule, Liquid, Liquid - Topical, Solution, Solution - Topical, Capsule, liquid filled, Capsule, liquid filled - Oral, Emulsion, Lotion, Lotion - Topical, Emulsion - Topical, Kit - Topical

Chloasma

, 0.0005 mg/mg, 0.001 mg/mg, 0.00025 mg/mg, 0.000375 mg/mg, 0.00075 mg/mg, 0.0001 mg/mg, 0.0002 mg/mg, 0.00005 mg/mg, 0.000025 mg/mg, 0.0004 mg/mg, 0.4 mL/mg, 0.001 mL/mg, 10.0 mg, 0.00001 mg/mg, 0.1 %, 0.025 %, 0.05 %, 0.01 %, 0.04 %, 0.00004 mg/mg, 0.0008 mg/mg, 0.1 mg/mL, 0.0006 mg/mg, 2.5 mg/mg, 0.5 mg/mL, 0.0025 mg/mg, 0.000015 mg/mg, 0.0000075 mg/mg

, Gel, Gel - Topical, Topical, Cream, Cream - Topical, Kit, Oral, Capsule - Oral, Capsule, Liquid, Liquid - Topical, Solution, Solution - Topical, Capsule, liquid filled, Capsule, liquid filled - Oral, Emulsion, Lotion, Lotion - Topical, Emulsion - Topical, Kit - Topical

Dermatologic disorders

, 0.0005 mg/mg, 0.001 mg/mg, 0.00025 mg/mg, 0.000375 mg/mg, 0.00075 mg/mg, 0.0001 mg/mg, 0.0002 mg/mg, 0.00005 mg/mg, 0.000025 mg/mg, 0.0004 mg/mg, 0.4 mL/mg, 0.001 mL/mg, 10.0 mg, 0.00001 mg/mg, 0.1 %, 0.025 %, 0.05 %, 0.01 %, 0.04 %, 0.00004 mg/mg, 0.0008 mg/mg, 0.1 mg/mL, 0.0006 mg/mg, 2.5 mg/mg, 0.5 mg/mL, 0.0025 mg/mg, 0.000015 mg/mg, 0.0000075 mg/mg

, Gel, Gel - Topical, Topical, Cream, Cream - Topical, Kit, Oral, Capsule - Oral, Capsule, Liquid, Liquid - Topical, Solution, Solution - Topical, Capsule, liquid filled, Capsule, liquid filled - Oral, Emulsion, Lotion, Lotion - Topical, Emulsion - Topical, Kit - Topical

Acne Vulgaris

, 0.0005 mg/mg, 0.001 mg/mg, 0.00025 mg/mg, 0.000375 mg/mg, 0.00075 mg/mg, 0.0001 mg/mg, 0.0002 mg/mg, 0.00005 mg/mg, 0.000025 mg/mg, 0.0004 mg/mg, 0.4 mL/mg, 0.001 mL/mg, 10.0 mg, 0.00001 mg/mg, 0.1 %, 0.025 %, 0.05 %, 0.01 %, 0.04 %, 0.00004 mg/mg, 0.0008 mg/mg, 0.1 mg/mL, 0.0006 mg/mg, 2.5 mg/mg, 0.5 mg/mL, 0.0025 mg/mg, 0.000015 mg/mg, 0.0000075 mg/mg

, Gel, Gel - Topical, Topical, Cream, Cream - Topical, Kit, Oral, Capsule - Oral, Capsule, Liquid, Liquid - Topical, Solution, Solution - Topical, Capsule, liquid filled, Capsule, liquid filled - Oral, Emulsion, Lotion, Lotion - Topical, Emulsion - Topical, Kit - Topical

benzyl violet

, 0.0005 mg/mg, 0.001 mg/mg, 0.00025 mg/mg, 0.000375 mg/mg, 0.00075 mg/mg, 0.0001 mg/mg, 0.0002 mg/mg, 0.00005 mg/mg, 0.000025 mg/mg, 0.0004 mg/mg, 0.4 mL/mg, 0.001 mL/mg, 10.0 mg, 0.00001 mg/mg, 0.1 %, 0.025 %, 0.05 %, 0.01 %, 0.04 %, 0.00004 mg/mg, 0.0008 mg/mg, 0.1 mg/mL, 0.0006 mg/mg, 2.5 mg/mg, 0.5 mg/mL, 0.0025 mg/mg, 0.000015 mg/mg, 0.0000075 mg/mg

, Gel, Gel - Topical, Topical, Cream, Cream - Topical, Kit, Oral, Capsule - Oral, Capsule, Liquid, Liquid - Topical, Solution, Solution - Topical, Capsule, liquid filled, Capsule, liquid filled - Oral, Emulsion, Lotion, Lotion - Topical, Emulsion - Topical, Kit - Topical

sun avoidance program

, 0.0005 mg/mg, 0.001 mg/mg, 0.00025 mg/mg, 0.000375 mg/mg, 0.00075 mg/mg, 0.0001 mg/mg, 0.0002 mg/mg, 0.00005 mg/mg, 0.000025 mg/mg, 0.0004 mg/mg, 0.4 mL/mg, 0.001 mL/mg, 10.0 mg, 0.00001 mg/mg, 0.1 %, 0.025 %, 0.05 %, 0.01 %, 0.04 %, 0.00004 mg/mg, 0.0008 mg/mg, 0.1 mg/mL, 0.0006 mg/mg, 2.5 mg/mg, 0.5 mg/mL, 0.0025 mg/mg, 0.000015 mg/mg, 0.0000075 mg/mg

, Gel, Gel - Topical, Topical, Cream, Cream - Topical, Kit, Oral, Capsule - Oral, Capsule, Liquid, Liquid - Topical, Solution, Solution - Topical, Capsule, liquid filled, Capsule, liquid filled - Oral, Emulsion, Lotion, Lotion - Topical, Emulsion - Topical, Kit - Topical

Skin

, 0.0005 mg/mg, 0.001 mg/mg, 0.00025 mg/mg, 0.000375 mg/mg, 0.00075 mg/mg, 0.0001 mg/mg, 0.0002 mg/mg, 0.00005 mg/mg, 0.000025 mg/mg, 0.0004 mg/mg, 0.4 mL/mg, 0.001 mL/mg, 10.0 mg, 0.00001 mg/mg, 0.1 %, 0.025 %, 0.05 %, 0.01 %, 0.04 %, 0.00004 mg/mg, 0.0008 mg/mg, 0.1 mg/mL, 0.0006 mg/mg, 2.5 mg/mg, 0.5 mg/mL, 0.0025 mg/mg, 0.000015 mg/mg, 0.0000075 mg/mg

, Gel, Gel - Topical, Topical, Cream, Cream - Topical, Kit, Oral, Capsule - Oral, Capsule, Liquid, Liquid - Topical, Solution, Solution - Topical, Capsule, liquid filled, Capsule, liquid filled - Oral, Emulsion, Lotion, Lotion - Topical, Emulsion - Topical, Kit - Topical

sun avoidance measures

, 0.0005 mg/mg, 0.001 mg/mg, 0.00025 mg/mg, 0.000375 mg/mg, 0.00075 mg/mg, 0.0001 mg/mg, 0.0002 mg/mg, 0.00005 mg/mg, 0.000025 mg/mg, 0.0004 mg/mg, 0.4 mL/mg, 0.001 mL/mg, 10.0 mg, 0.00001 mg/mg, 0.1 %, 0.025 %, 0.05 %, 0.01 %, 0.04 %, 0.00004 mg/mg, 0.0008 mg/mg, 0.1 mg/mL, 0.0006 mg/mg, 2.5 mg/mg, 0.5 mg/mL, 0.0025 mg/mg, 0.000015 mg/mg, 0.0000075 mg/mg

, Gel, Gel - Topical, Topical, Cream, Cream - Topical, Kit, Oral, Capsule - Oral, Capsule, Liquid, Liquid - Topical, Solution, Solution - Topical, Capsule, liquid filled, Capsule, liquid filled - Oral, Emulsion, Lotion, Lotion - Topical, Emulsion - Topical, Kit - Topical

Hand

, 0.0005 mg/mg, 0.001 mg/mg, 0.00025 mg/mg, 0.000375 mg/mg, 0.00075 mg/mg, 0.0001 mg/mg, 0.0002 mg/mg, 0.00005 mg/mg, 0.000025 mg/mg, 0.0004 mg/mg, 0.4 mL/mg, 0.001 mL/mg, 10.0 mg, 0.00001 mg/mg, 0.1 %, 0.025 %, 0.05 %, 0.01 %, 0.04 %, 0.00004 mg/mg, 0.0008 mg/mg, 0.1 mg/mL, 0.0006 mg/mg, 2.5 mg/mg, 0.5 mg/mL, 0.0025 mg/mg, 0.000015 mg/mg, 0.0000075 mg/mg

, Gel, Gel - Topical, Topical, Cream, Cream - Topical, Kit, Oral, Capsule - Oral, Capsule, Liquid, Liquid - Topical, Solution, Solution - Topical, Capsule, liquid filled, Capsule, liquid filled - Oral, Emulsion, Lotion, Lotion - Topical, Emulsion - Topical, Kit - Topical

keratinization disorders of the feet

, 0.0005 mg/mg, 0.001 mg/mg, 0.00025 mg/mg, 0.000375 mg/mg, 0.00075 mg/mg, 0.0001 mg/mg, 0.0002 mg/mg, 0.00005 mg/mg, 0.000025 mg/mg, 0.0004 mg/mg, 0.4 mL/mg, 0.001 mL/mg, 10.0 mg, 0.00001 mg/mg, 0.1 %, 0.025 %, 0.05 %, 0.01 %, 0.04 %, 0.00004 mg/mg, 0.0008 mg/mg, 0.1 mg/mL, 0.0006 mg/mg, 2.5 mg/mg, 0.5 mg/mL, 0.0025 mg/mg, 0.000015 mg/mg, 0.0000075 mg/mg

, Gel, Gel - Topical, Topical, Cream, Cream - Topical, Kit, Oral, Capsule - Oral, Capsule, Liquid, Liquid - Topical, Solution, Solution - Topical, Capsule, liquid filled, Capsule, liquid filled - Oral, Emulsion, Lotion, Lotion - Topical, Emulsion - Topical, Kit - Topical

Warnings

Retin-A Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Tretinoin may interact with Pulse Frequency

There are 20 known major drug interactions with Retin-A.

Common Retin-A Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Tretinoin is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Tretinoin is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abetimus

Major

The risk or severity of adverse effects can be increased when Tretinoin is combined with Abetimus.

Acteoside

Major

The risk or severity of adverse effects can be increased when Tretinoin is combined with Acteoside.

Aldosterone

Major

The risk or severity of adverse effects can be increased when Tretinoin is combined with Aldosterone.

image of a doctor in a lab doing drug, clinical research

Retin-A Novel Uses: Which Conditions Have a Clinical Trial Featuring Retin-A?

65 active clinical trials are currently in progress to explore the potential of Retin-A to treat Chloasma, Acne and Alopecia.

Condition

Clinical Trials

Trial Phases

Chloasma

0 Actively Recruiting

Alopecia

14 Actively Recruiting

Early Phase 1, Not Applicable, Phase 3, Phase 2, Phase 1

mottled hyperpigmentation

0 Actively Recruiting

severe, recalcitrant Cystic acne

0 Actively Recruiting

keratinization disorders of the feet

0 Actively Recruiting

tactile roughness of facial skin

0 Actively Recruiting

Skin

0 Actively Recruiting

Dermatologic disorders

0 Actively Recruiting

Hyperpigmentation

0 Actively Recruiting

Fine Wrinkles

0 Actively Recruiting

Hand

0 Actively Recruiting

Chloasma

0 Actively Recruiting

sun avoidance measures

0 Actively Recruiting

Acute Promyelocytic Leukemia

0 Actively Recruiting

Acne Vulgaris

3 Actively Recruiting

Phase 1, Phase 2, Early Phase 1, Phase 4

benzyl violet

0 Actively Recruiting

sun avoidance program

0 Actively Recruiting

Retin-A Reviews: What are patients saying about Retin-A?

5

Patient Review

2/28/2010

Retin-A for Acne

I had a bad reaction to this medicine. It gave me a tumor-like growth. I spent weeks out of school and had debilitating headaches. I would pass out and needed spinal taps to relieve the pressure in my head. The only upside is that it didn't affect my sight.

5

Patient Review

8/18/2010

Retin-A for Acne

I was given a small sample of this product by a friend, and it completely changed my life. I had been searching for years to find out what it was, and finally tracked her down so I could get the name. This stuff is amazing--not only does it get rid of acne, but it also fades scars quickly.

4.7

Patient Review

12/4/2021

Retin-A for Acne

This cream really did wonders for my acne and oiliness. I was hesitant to try it at first because of the possibility of a "purge" but I only experienced some slight dryness.

4.3

Patient Review

11/9/2013

Retin-A for Acne

When I first started using this medication, my skin was really dry and flaky. But, if you stick with it, the flakiness will go away and your acne will be 100% better than before.

4.3

Patient Review

10/29/2010

Retin-A for Acne

I had to increase the dosage, which made my skin red and dry. However, it was worth it because my skin looks great now. My mother also uses this medication and it has worked well for her too.

3.7

Patient Review

10/19/2015

Retin-A for Acne

I didn't experience any terrible side effects, which is great. I followed the directions and waited before starting the product, as recommended. My acne has improved after using this for nine weeks; however, it's not the miracle cure-all I was hoping for. It did help with my blackheads though.

2.3

Patient Review

2/22/2017

Retin-A for Acne

Retin-A was not at all effective for me in terms of acne reduction. Additionally, it made my skin red and irritated. The only plus side is that it was easy to use!

2

Patient Review

1/26/2010

Retin-A for Acne

I began using this for acne, but it's also helped clear up my melasma. I'm really happy with the results and several friends have commented on how good my skin looks recently without knowing that I've been using this new treatment.

1.3

Patient Review

1/21/2016

Retin-A for Acne

I had a couple of small pimples when I started this cream, but by week three my acne was out of control. It was horrible--I've never seen anything like it. And even after stopping the cream two weeks ago, I'm still not seeing any improvement. Do not use this product!
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about retin-a

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Retin-A and retinol the same thing?

"Retin-A and retinol are both forms of vitamin A that help promote skin renewal. Retin-A eliminates the buildup of dead skin cells, unclogs pores, and promotes the production of healthy, new skin cells. Unlike retinol, Retin-A is already in retinoic acid form, so the skin does not need to convert it."

Answered by AI

How do I get Retin-A?

"Tretinoin Cream is available only with a prescription because it is stronger than over-the-counter retinol products. After reviewing your medical history, Nurx medical providers will prescribe Tretinoin Cream if appropriate. Nurx ships your prescription privately, safely, and discreetly through the mail."

Answered by AI

Do I need A prescription for Retin-A?

"Retin-A is a prescription-only topical medicine that is applied sparingly to the facial skin, avoiding the eyelids, corners of the nose and lips. It works at the cellular level and takes several months to see the full effect."

Answered by AI

What does Retin-A do to your skin?

"Retin-A is a form of vitamin A that helps the skin renew itself. The Retin-A and Avita brands of tretinoin are used to treat acne. The Renova brand of tretinoin is used to reduce the appearance of fine wrinkles and mottled skin discoloration, and to make rough facial skin feel smoother."

Answered by AI

Clinical Trials for Retin-A

Image of Advanced Dermatology & Cosmetic Surgery in Maitland, United States.

Xtresse Serum for Hair Loss

18 - 65
All Sexes
Maitland, FL

The goal of this study is to determine how safe and effective it is to improve hair growth by applying a serum daily on the scalp of men and women with thinning hair. The main aims of this trial are: 1. To confirm using photographic analysis, changes in the quality, volume, and thickness of hair. 2. To gauge patient satisfaction with hair changes and application process. 3. Monitor and report any adverse events associated with the daily usage of Xtressé serum. Participants who qualify will complete 4 visits after voluntary consent has been given. Participants will be given 4 bottles of serum to use during the study. The product will be applied daily over a 4-month period. Photographs and scalp analysis will be performed at each visit to measure changes in hair volume, thickness, and growth. Participants will complete a survey at the end of the study.

Waitlist Available
Has No Placebo

Advanced Dermatology & Cosmetic Surgery (+2 Sites)

Melissa Rayner, MS

Restore Biologics Holdings, Inc. dba Xtressé

Image of Advanced Dermatology & Cosmetic Surgery in Maitland, United States.

Xtressé Gummies for Alopecia

18 - 65
Female
Maitland, FL

The goal of this study is to determine how safe and effective it is to improve hair growth using an active gummy treatment in women with self-perceived thinning hair. The main aims of this trial are: 1. To confirm using photographic analysis, changes in the quality, volume, and thickness of hair. 2. To gauge patient satisfaction with hair changes and application process. 3. Monitor and report any adverse events associated with the daily intake of Xtressé Participants who qualify will complete 5 visits after voluntary consent has been given. Participants will be given a 30-day supply of the gummies at each visit over a 4-month period. Photographs and scalp analysis will be performed at each visit to measure changes in hair volume, thickness, and growth.

Waitlist Available
Has No Placebo

Advanced Dermatology & Cosmetic Surgery (+3 Sites)

Melissa Y Rayner, MS

Restore Biologics Holdings, Inc. dba Xtressé

Image of Advanced Dermatology & Cosmetic Surgery in Maitland, United States.

XVIE for Alopecia

28 - 65
Female
Maitland, FL

The goal of this study is to determine how safe and effective it is to improve hair growth using XVIE solution applied on the scalp of women with self-perceived thinning hair. The main aims of this trial are: 1. To confirm using photographic analysis, changes in the quality, volume, and thickness of hair. 2. To gauge patient satisfaction with hair changes and application process. Participants who qualify will complete 5 to 6 visits after voluntary consent has been given. Participant's scalp will be numbed and the XVIE solution will be applied by microneedling. Photographs will be taken at each visit to measure changes in hair volume, thickness, and growth. Every participant will receive active treatment twice over the 4 month period.

Waitlist Available
Has No Placebo

Advanced Dermatology & Cosmetic Surgery (+1 Sites)

Melissa Y Rayner, MS

Restore Biologics Holdings, Inc. dba Xtressé

Have you considered Retin-A clinical trials?

We made a collection of clinical trials featuring Retin-A, we think they might fit your search criteria.
Go to Trials
Image of Skin Wellness Dermatology in Birmingham, United States.

Xtressé Supplement and Serum for Alopecia

28 - 65
Female
Birmingham, AL

The goal of this clinical trial is to test how safe and effective it is to improve hair growth using an active gummy and serum combination treatment when compared to an inactive treatment combination in women with self-perceived thinning hair. The main questions this trial aims to answer are: * to confirm using photograph analytics, how much hair growth has increased in a marked area when using active treatment versus inactive treatment, and * participants assessment and satisfaction with the hair growth using scaled assessments. Participants who qualify will be asked to complete 6 to 7 visits after voluntarily consent has been given. The study is divided into two parts. In Part A participants will be randomly given either active or inactive treatment to use over 3 months. After 3 months, all participants will enter Part B of the study and will be given active treatment to use over the final 6 months of the study.

Recruiting
Paid Trial

Skin Wellness Dermatology (+1 Sites)

Danielle Leavitt

Restore Biologics Holdings, Inc. dba Xtressé

Image of Marc Avram MD in New York, United States.

TargetCool + Benev Exosomes for Alopecia

18 - 70
All Sexes
New York, NY

This clinical trial is testing a new approach to help improve hair thinning using a combination of cosmetic treatments. The purpose of the study is to learn whether applying exosomes to the scalp, along with microneedling and a precision cooling device called TargetCool™. This study aims to determine whether this combination approach offers synergistic benefits for individuals with hair thinning. Exosomes are tiny particles that come from stem cells and contain growth factors and other nutrients. They are being studied for their potential to help regenerate skin and hair. TargetCool™ is an FDA-cleared device that uses precision cooling to reduce inflammation and improve comfort. Microneedling is a common, minimally invasive procedure that uses small needles to stimulate the skin and help absorb topical products more effectively. The study will include healthy men (ages 18 to 70) and women (ages approximately 45 to 70) who are not of childbearing potential. A total of 9 to 15 participants will be randomly placed into one of three groups: Group 1: Exosomes with TargetCool™ Group 2: Microneedling followed by exosomes and TargetCool™ Group 3: Microneedling followed by exosomes only Participants will receive four treatments over 9 weeks. Each visit may include microneedling, TargetCool™ treatment, and exosome application depending on group assignment. A small tattoo will be placed on the scalp to help capture consistent photographs, and a special imaging system (Canfield HairMetrix®) will be used to measure hair changes. Participants will return for follow-up visits at 3 and 6 months after the final treatment. The results will help determine whether this combination of cosmetic treatments is safe and beneficial for people experiencing hair thinning.

Waitlist Available
Has No Placebo

Marc Avram MD

Dawn Queen, MD

Recens Medical, Inc.

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Have you considered Retin-A clinical trials?

We made a collection of clinical trials featuring Retin-A, we think they might fit your search criteria.
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