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What is Relpax
EletriptanThe Generic name of this drug
Treatment SummaryEletriptan is a medication created by Pfizer that can be used to treat migraine headaches. It belongs to a class of drugs called triptans.
Relpaxis the brand name
Relpax Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Relpax
Eletriptan
2002
26
Effectiveness
How Relpax Affects PatientsEletriptan triggers certain receptors in the body and has been shown to reduce the flow of blood through the carotid artery. This has a small effect on the blood pressure in high doses. Other arteries, such as the coronary artery, also become narrower. In rats, it has been observed to reduce activity of the trigeminal nerve.
How Relpax works in the bodyEletriptan binds to certain serotonin receptors in the brain to help relieve migraines. The exact way this works is unclear, but it is thought that by binding to these receptors, it causes blood vessels in the brain to constrict, which leads to a reduction in migraine symptoms. It is also believed to block the release of certain chemicals that cause inflammation and pain.
When to interrupt dosage
The measure of Relpax is contingent upon the diagnosed state. The magnitude of the dosage is contingent upon the approach of conveyance (e.g. Tablet, film coated - Oral or Tablet, film coated) detailed in the table hereunder.Condition
Dosage
Administration
Migraine Without Aura
, 20.0 mg, 40.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral
Migraine With Aura
, 20.0 mg, 40.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral
Warnings
Relpax ContraindicationsCondition
Risk Level
Notes
intestinal ischemia
Do Not Combine
Basilar Migraine
Do Not Combine
Coronary Artery Vasospasm
Do Not Combine
Pulse Frequency
Do Not Combine
history of stroke
Do Not Combine
Pulse Frequency
Do Not Combine
arrhythmias associated with conduction disorders
Do Not Combine
Peripheral Vascular Disease
Do Not Combine
Pulse Frequency
Do Not Combine
Anomalous atrioventricular excitation
Do Not Combine
Pulse Frequency
Do Not Combine
Transient Ischemic Attack
Do Not Combine
Pulse Frequency
Do Not Combine
Hypertensive disease
Do Not Combine
Coronary Artery Disease
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Hemiplegic migraine
Do Not Combine
Common Relpax Drug Interactions
Drug Name
Risk Level
Description
Amitriptyline
Major
The metabolism of Amitriptyline can be decreased when combined with Eletriptan.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Eletriptan.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Eletriptan.
Azelastine
Major
Eletriptan may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Capmatinib
Major
The serum concentration of Capmatinib can be decreased when it is combined with Eletriptan.
Relpax Toxicity & Overdose RiskTaking too much of a 5-HT1B/1D agonist could lead to high blood pressure or other serious heart-related issues.
Relpax Novel Uses: Which Conditions Have a Clinical Trial Featuring Relpax?
Currently, 4 active studies are assessing the potential of Relpax to provide relief for Migraine Without Aura.Condition
Clinical Trials
Trial Phases
Migraine With Aura
3 Actively Recruiting
Not Applicable
Migraine Without Aura
2 Actively Recruiting
Not Applicable
Relpax Reviews: What are patients saying about Relpax?
5Patient Review
12/13/2015 Despite my insurance only giving me a measly six Relpax per month (I need at least 20), this drug has always been effective for me in the past. It works within an hour to several, which is really incredible. Sadly, my doctor doesn't like fighting with my insurance company, so I have to make due with what little I'm given.
5Patient Review
2/11/2016 I've been dealing with migraines since I was a teenager, but Relpax has always been effective for me. It does cause some temporary weakness, but that's a small price to pay for getting rid of the migraine.
5Patient Review
7/10/2017 These pills are incredible for migraines. Within 45 minutes of taking them, I can go about my day as normal. So glad that insurance covers most of the cost because they're not cheap.
5Patient Review
12/10/2016 I've been taking 40 mg of Relpax for quite a few years with no side effects. I strongly suggest this drug to anyone I know that has chronic migraines.
5Patient Review
5/18/2018 I've tried all the other triptans, and they all help to some extent. However, Relpax is the only one that works for me every single time--though sometimes I have to take two pills. One commenter here said that the FDA only allows two pills per week, but that's not true. The limit is two per 24 hours.
5Patient Review
12/15/2017 This is the only medication that has been able to entirely relieve my migraines. Sometimes I have to take two pills, but it's worth it when the pain goes away. The price can be prohibitive, though I've had to pay as much as $50 per pill at times.
5Patient Review
9/5/2017 This medication is great for migraines. It usually takes the pain down from a 10+ to a 4 or 5, which is much more manageable. However, it is dangerous to take more than two doses per week, so I often have to supplement with narcotics.
5Patient Review
5/9/2021 Relax is great for when I'm feeling anxious or stressed. Within fifteen minutes, I'm back to being productive without any sort of side effects.
5Patient Review
5/22/2021 Relpax is great for when I need to be productive despite having a headache or migraine.
5Patient Review
5/3/2016 Relpax has been a game-changer for me when it comes to managing my migraines. I've tried other medications in the past, but their side effects were almost as bad as the migraine itself. If you're debating whether or not to take this medication, just do it! The sooner you take it, the better chance you have of preventing the headache from getting worse.
4.3Patient Review
10/29/2019 This treatment saved my life.
1.3Patient Review
4/26/2019 I've been on this prescription for a couple years now and, to be frank, I haven't found it helpful at all. The two hour wait between pills is torture, and my insurance only covers so many per month. Time to try something else.
1Patient Review
2/7/2017 The first time I took Relpax, it made me so nauseous that I had to lay down and not move. I also felt very hazy and ended up passing out for four hours. Not only did it not help with my migraine, but it actually made the pain worse. I usually have migraines that last one day, but after taking this medication, my migraine lasted for three days. It was the worst experience of my life and I will never take this drug again.
1Patient Review
10/14/2015 This medication was prescribed by a doctor for my son, but it hasn't helped him at all.
Patient Q&A Section about relpax
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What drug class is Relpax?
"Relpax is an antimigraine medication containing the drug eletriptan which belongs to a class of drugs known as triptans. Triptans work by narrowing swollen blood vessels in your brain which can lead to less pain."
Answered by AI
Why was Relpax recalled?
"This is a voluntary recall for 2 lots of RELPAX® (eletriptan hydrobromide) 40 mg Tablets. The reason is potential microbial contamination of the non-sterile products."
Answered by AI
What is Relpax prescribed for?
"Triptans can help to relieve headaches, pain, and other symptoms associated with migraines, such as nausea, vomiting, and sensitivity to light and sound. Getting prompt treatment can help you get back to your normal routine and may reduce your need for other pain medications."
Answered by AI
How does Relpax make you feel?
"You may have discomfort in your jaw, throat, neck, or chest after taking a dose of Relpax. Some people had this side effect in the drug's clinical trials, though it was less common. Symptoms may include the following sensations in the jaw, throat, neck, or chest: pain, pressure, or tightness."
Answered by AI