Prednisone Intensol

Pemphigus, Ophthalmia, Sympathetic, Chorioretinitis + 95 more
Treatment
55 FDA approvals
20 Active Studies for Prednisone Intensol

What is Prednisone Intensol

PrednisoneThe Generic name of this drug
Treatment SummaryPrednisone is a synthetic anti-inflammatory medication derived from cortisone. It works by reducing inflammation in the body and can be converted to prednisolone in the liver. Prednisone was approved by the FDA in 1955.
PredniSONEis the brand name
image of different drug pills on a surface
Prednisone Intensol Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
PredniSONE
Prednisone
1972
681

Approved as Treatment by the FDA

Prednisone, commonly known as PredniSONE, is approved by the FDA for 55 uses which include Anemia, Hemolytic and Uremia .
Anemia, Hemolytic
Uremia
Mycosis Fungoides (MF)
Helps manage Mycosis Fungoides (MF)
Thrombocytopenia
Conjunctivitis
Helps manage Ocular Inflammation
Secondary thrombocytopenia
Diuresis
Allergic Rhinitis (AR)
Helps manage Allergic Rhinitis (AR)
non-suppurative Thyroiditis
Primary adrenocortical insufficiency
Adrenal Cortex Hormones
Helps manage unresponsive to topical corticosteroids
acquired immune hemolytic anemia
Crohn Disease
Helps manage acute Crohn's Disease (CD)
Atopic Dermatitis
Helps manage Atopic Dermatitis
Congenital Hypoplastic Anemia
Congenital Adrenal Hyperplasia (CAH)
Neurologic Involvement
Immune Thrombocytopenia (ITP)
Disseminated tuberculosis
Used to treat Disseminated tuberculosis in combination with Aminosalicylic acid
Drug hypersensitivity reaction
Contact Dermatitis
Mycosis Fungoides
Helps manage Mycosis Fungoides (MF)
Thyroiditis
Ulcerative Colitis
Helps manage Ulcerative Colitis
Sarcoidosis
Helps manage symptomatic Sarcoidosis
Secondary adrenocortical insufficiency
Malignant Neoplasms
Stevens-Johnson Syndrome
induction of Diuresis
Idiopathic Nephrotic Syndrome
symptomatic Sarcoidosis
Helps manage symptomatic Sarcoidosis
Asthma
Helps manage Asthma
Ulcerative Colitis
Helps manage Ulcerative Colitis
Ocular Inflammation
Helps manage Ocular Inflammation
Pemphigus
Helps manage Pemphigus
Trichinosis
Pemphigus
Helps manage Pemphigus
Systemic Lupus Erythematosus (SLE)
Adrenal Insufficiency
Addison Disease
Lupus Erythematosus
Proteinuria
Uremia
Bullous dermatitis herpetiformis
Helps manage Bullous dermatitis herpetiformis
Tuberculosis
Used to treat fulminating Tuberculosis in combination with Aminosalicylic acid
Serum Sickness
exfoliative erythroderma
Helps manage exfoliative erythroderma
Anemia, Diamond-Blackfan
Lupus
Congenital adrenal hyperplasia
Patient Participation
Tuberculosis
Used to treat Disseminated tuberculosis in combination with Aminosalicylic acid
Aspiration Pneumonitis
Drug Allergy
Asthma
Helps manage Asthma

Effectiveness

How Prednisone Intensol Affects PatientsCorticosteroids like prednisone work by attaching to the glucocorticoid receptor in the body. This helps to reduce inflammation and keep it under control. Prednisone works quickly but has a short duration, lasting only 2-3 hours. It is a powerful drug but can be taken safely as long as a person is aware of the risks of HPA axis suppression and infection.
How Prednisone Intensol works in the bodyPrednisone is changed in the liver to its active form, prednisolone. This corticosteroid helps reduce inflammation in the body. It does this by blocking blood vessel widening, reducing the flow of white blood cells to sites of inflammation, and preventing neutrophil death. It also stops the production of arachidonic acid derivatives, and increases anti-inflammatory genes like interleukin-10. Lower doses of prednisolone reduce inflammation, while higher doses act as an immunosuppressant. High doses of prednisolone also bind to the mineralocorticoid receptor, raising sodium levels

When to interrupt dosage

The quantity of Prednisone Intensol is hinged upon the diagnosed illness, including Malignant Lymphomas, Thyroiditis and Tuberculosis Meningitis. The amount of dosage is contingent upon the delivery procedure (e.g. Oral or Solution, concentrate) specified in the table hereunder.
Condition
Dosage
Administration
Dermatomyositis
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
prophylaxis of graves ophthalmopathy
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
Craniotomy
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
exfoliative erythroderma
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
Addison Disease
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
varicella-zoster virus acute retinal necrosis
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
Psoriasis
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
Trichinosis
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
induction of Diuresis
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
Diuresis
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
Sarcoidosis
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
Brain
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
Brain
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
Optic Neuritis
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
Congenital adrenal hyperplasia
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
Malignant Neoplasms
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
HIV Positive
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
Red-Cell Aplasia, Pure
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
Psoriatic Arthritis
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit
Ulcerative Colitis
, 5.0 mg/mL, 2.5 mg, 10.0 mg, 5.0 mg, 20.0 mg, 1.0 mg, 50.0 mg, 0.2 mg, 0.1 mg, 2.0 mg/mg, 2.0 mg, 5.0 mg/mg
, Oral, Solution, Solution - Oral, Tablet - Oral, Tablet, Solution, concentrate - Oral, Solution, concentrate, Tablet, delayed release - Oral, Tablet, delayed release, Kit

Warnings

Prednisone Intensol has two contraindications and therefore should not be consumed when experiencing any of the conditions displayed in the table below.Prednisone Intensol Contraindications
Condition
Risk Level
Notes
Mycoses
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Prednisone may interact with Pulse Frequency
There are 20 known major drug interactions with Prednisone Intensol.
Common Prednisone Intensol Drug Interactions
Drug Name
Risk Level
Description
2-Methoxyethanol
Major
The risk or severity of adverse effects can be increased when Prednisone is combined with 2-Methoxyethanol.
9-(N-methyl-L-isoleucine)-cyclosporin A
Major
The risk or severity of adverse effects can be increased when Prednisone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Abatacept
Major
The risk or severity of adverse effects can be increased when Prednisone is combined with Abatacept.
Abetimus
Major
The risk or severity of adverse effects can be increased when Prednisone is combined with Abetimus.
Acteoside
Major
The risk or severity of adverse effects can be increased when Prednisone is combined with Acteoside.
Prednisone Intensol Toxicity & Overdose RiskTaking high doses of prednisone for a long time can cause a variety of side effects, including mental disturbances, round face, excess fat in certain areas, fluid build-up, increased appetite, weight gain, excessive body hair, acne, red stretch marks, easy bruising, increased sweating, skin discoloration, thinning scalp hair, high blood pressure, rapid heart rate, inflammation of veins, decreased immunity to infection, slower bone and wound healing, headaches, fatigue, menstrual problems, worsening menopause symptoms, nerve pain, fractures, weak bones, ulcers in the stomach, decreased tolerance to sugar, low levels of potassium
image of a doctor in a lab doing drug, clinical research

Prednisone Intensol Novel Uses: Which Conditions Have a Clinical Trial Featuring Prednisone Intensol?

Currently, 70 active studies are evaluating the potential of Prednisone Intensol to provide relief from Adrenal Cortex Hormones, Disseminated Tuberculosis and Idiopathic Thrombocytopenic Purpura.
Condition
Clinical Trials
Trial Phases
Drug Allergy
2 Actively Recruiting
Phase 3, Phase 2
Asthma
92 Actively Recruiting
Phase 1, Phase 4, Early Phase 1, Phase 2, Not Applicable, Phase 3
Tuberculosis
0 Actively Recruiting
Relapsing Polychondritis
1 Actively Recruiting
Phase 2
Giant Cell Arteritis
3 Actively Recruiting
Phase 3, Phase 1, Phase 2
Lupus
65 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 3, Phase 4, Early Phase 1
Tennis Elbow
0 Actively Recruiting
Acute Coryza
0 Actively Recruiting
Ulcerative Colitis
14 Actively Recruiting
Phase 3, Phase 2, Not Applicable, Phase 4, Phase 1
Bell Palsy
0 Actively Recruiting
Polymyalgia Rheumatica
3 Actively Recruiting
Phase 3, Phase 2
Patient Participation
0 Actively Recruiting
Crohn Disease
0 Actively Recruiting
Chorioretinitis
0 Actively Recruiting
Acne Vulgaris
2 Actively Recruiting
Phase 1, Phase 2, Early Phase 1
Brain
7 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1
acute Bursitis
0 Actively Recruiting
Brain
0 Actively Recruiting
Arthritis, Juvenile
1 Actively Recruiting
Not Applicable
Bullous dermatitis herpetiformis
0 Actively Recruiting

Prednisone Intensol Reviews: What are patients saying about Prednisone Intensol?

5Patient Review
5/7/2009
Prednisone Intensol for Joint Disease which may include Attacks of Acute Arthritis
This treatment saved my life. Plain and simple.
5Patient Review
8/30/2015
Prednisone Intensol for Giant Hives
I was unable to sleep while taking this drug; I would go days without any rest. Additionally, it's apparently common knowledge that this drug can cause bone deterioration. If you're going to be taking it for a prolonged period of time, make sure to get your bone density checked regularly.
5Patient Review
6/16/2017
Prednisone Intensol for Rheumatic Disease causing Pain & Stiffness in Backbone
This medication has been a godsend. It's helped me so much with my polymyalgia rheumatica and I'm able to live a normal life again thanks to it.
5Patient Review
1/24/2016
Prednisone Intensol for Sarcoidosis
The side effects of this medication were unfortunately worse than the illness it was treating.
5Patient Review
11/8/2007
Prednisone Intensol for Obstructive Pulmonary Disease
5Patient Review
6/10/2008
Prednisone Intensol for Inflammation of the Joints due to Gout
5Patient Review
9/26/2008
Prednisone Intensol for Cluster Headache Prevention
5Patient Review
10/26/2008
Prednisone Intensol for Joint Disease which may include Attacks of Acute Arthritis
4.3Patient Review
6/24/2015
Prednisone Intensol for Multiple Sclerosis
I was on this drug for a long time, and it effectively decreased my libido. I was told that it would come back when I stopped taking the medication, but unfortunately that has not been the case.
4Patient Review
5/17/2016
Prednisone Intensol for Asthma
It's been such a relief to find something that actually helps with my chronic symptoms. This drug has made a huge difference for me, after more than a year of struggling.
4Patient Review
11/18/2008
Prednisone Intensol for Crohn's Disease
3.7Patient Review
9/19/2017
Prednisone Intensol for Bell's Palsy Paralysis of One Side of the Face
I was on a high dosage of prednisone for several weeks, and while it did improve my Bell's Palsy symptoms, I experienced some very unpleasant side effects. Now that I'm tapering off the drug, I'm experiencing adrenal fatigue. In other words, the withdrawal is almost as bad as the side effects.
3.3Patient Review
1/16/2013
Prednisone Intensol for Asthma
This medication is really great. It helps with my pain and I can walk while taking it, which is a huge plus. The only downside is that it doesn't last very long.
3Patient Review
4/28/2015
Prednisone Intensol for Crohn's Disease
I experienced swelling in my extremities, which was painful. I also gained weight and felt pressure in my head. This drug made me very hyperactive and unable to sit still or stand for long periods of time.
3Patient Review
2/27/2009
Prednisone Intensol for Rheumatoid Arthritis
I'm concerned about how long-term this medication is.
3Patient Review
6/22/2015
Prednisone Intensol for Crohn's Disease
Though it can be irritating, this treatment is quite effective- especially when used on short notice.
2.3Patient Review
1/4/2016
Prednisone Intensol for Low Platelet Count and Bleeding from Immune Response
I've found that taking this drug for three to five days when I have a flare-up of my MS symptoms provides the most benefit. The biggest issues I experience are insomnia, muscle soreness/tenderness, flushing, heartburn and water blisters; however, overall the outcome is most beneficial and I am extremely thankful for the benefits of this drug.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about prednisone intensol

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is an Intensol medication?

"Lorazepam Intensol is a type of benzodiazepine that is typically used to treat anxiety disorders. However, it may also have other uses not mentioned in this guide."

Answered by AI

What classification of the drug is prednisone prednisone Intensol )?

"Prednisone is a drug that belongs to a class of drugs known as corticosteroids. It is used to reduce the symptoms of various diseases by decreasing the response of the immune system."

Answered by AI

What is prednisone Intensol used for?

"Prednisone is employed to ameliorate conditions such as arthritis, blood disorders, breathing difficulties, severe allergies, skin diseases, cancer, eye problems, and immune system disorders. Prednisone is a member of a class of medications called corticosteroids."

Answered by AI

Is prednisone Intensol the same as prednisone?

"Prednisone Intensol is a liquid solution with a high concentration of prednisone (5 mg per mL) for patients who may have difficulty taking a tablet or a lower-concentration lower solution."

Answered by AI

Clinical Trials for Prednisone Intensol

Image of Investigative Site in Beverly Hills, United States.

VENT-03 for Lupus

18 - 70
All Sexes
Beverly Hills, CA
The goal of this clinical trial is to learn if VENT-03 works to treat patients with cutaneous lupus erythematosus (CLE) who may or may not have systemic lupus erythematosus (SLE). Another goal is to learn about the safety of VENT-03 and how it is processed by the body. The main questions it aims to answer are: * Does VENT-03 affect the activity and severity of CLE? * What side effects do participants have when taking VENT-03? Researchers will compare VENT-03 to a placebo (a look-alike substance that contains no drug) to see if VENT-03 works to treat patients with CLE. Participants will: * Take VENT-3 or a placebo every day for 4 weeks, then all participants will switch to VENT-03 for another 8 weeks; * Visit the clinic once a month for checkups and tests.
Phase 2
Recruiting
Investigative Site (+9 Sites)Ventus Therapeutics U.S., Inc.
Image of University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center in Cleveland, United States.

Whole Brain Radiotherapy for Brain Cancer

18+
All Sexes
Cleveland, OH
Participants in this research study have cancer that has spread to their brain, called brain metastases. One treatment for this type of cancer is called whole brain radiotherapy that stays away from a specific neurocognitive substructure, called the hippocampus, combined with medication to preserve cognitive function. This study compares that approach to another approach of whole brain radiotherapy that stays away from additional structures that are thought to have a role in cognitive function. Researchers want to see if there is a difference in the preservation of cognitive function between these two approaches.
Phase 2
Waitlist Available
University Hospitals Seidman Cancer Center, Case Comprehensive Cancer CenterHaley Perlow, MD
Image of Sunnybrook Health Sciences Centre in Toronto, Canada.

Steroids for Rheumatoid Arthritis

18+
All Sexes
Toronto, Canada
People living with rheumatoid arthritis (RA) often experience flares-periods where their symptoms suddenly get worse. These flares can cause significant pain, make it harder to move and do daily activities, and lower overall quality of life. Doctors often treat flares with medications called glucocorticoids (GCs), which reduce inflammation. These medications can be taken by mouth (oral/PO) or given as a single injection into the muscle (intramuscular/IM). However, it's not clear which option works better from the patient's point of view-especially when it comes to relief of symptoms, improvements in function, and satisfaction with treatment. Most research so far has focused on how well the drugs control the disease, rather than how they impact the patient's overall experience. Research Questions: 1. Does a single GC injection work just as well as taking pills over a few weeks in improving symptoms reported by patients? 2. How do the two treatments compare in terms of symptom relief, ability to function, and patient satisfaction? 3. What do patients think and feel about using GCs to treat RA flares? What the Investigators Think: The investigators believe that a one-time GC injection is just as good as taking pills for a few weeks when it comes to managing RA flares. In fact, the injection might even be safer and preferred by patients. What the Investigators are Doing: The investigators will study 220 adults with RA who are currently having a flare (with at least 3 swollen and tender joints). These patients will be recruited from rheumatology clinics at the University of Toronto and must not have used GCs in the past month. They will be randomly assigned to receive either: A single injection (Methylprednisolone 120 mg), or Oral pills (Prednisone starting at 15 mg daily and tapering down over 3 weeks). The main thing the investigators will look at is how much better patients feel after 6 weeks, based on a questionnaire designed to measure RA flares. The investigators will also look at how well they function, how satisfied they are with the treatment, and whether they had any side effects. In addition, 20 patients (10 from each group) will be interviewed to understand their experiences and opinions about flare treatment in more detail. Why This Is Possible: The investigators have already surveyed University of Toronto rheumatologists who support the idea and provided input on study design. The investigators have also partnered with experts in research methods, national arthritis organizations, and patient groups to make sure the study is relevant and meaningful. Ethics approval has been obtained. Why It Matters: RA flares can have a major impact on people's lives. While current treatments help control inflammation, the investigators need to better understand how these treatments affect people from their own perspective. This study will shift the focus to what matters most to patients, helping doctors and patients choose the best treatment based not only on medical results but also on the patient's experience. This could lead to more effective and personalized care for people living with RA.
Phase 4
Waitlist Available
Sunnybrook Health Sciences Centre (+4 Sites)
Have you considered Prednisone Intensol clinical trials? We made a collection of clinical trials featuring Prednisone Intensol, we think they might fit your search criteria.Go to Trials
Image of Weill Cornell Medical College in New York, United States.

Health Coaching for Rheumatoid Arthritis

18+
All Sexes
New York, NY
The goal of this clinical trial is to learn if peer coaching works to reduce levels of anxiety and/or depression in adults diagnosed with Rheumatoid Arthritis (RA). The main questions it aims to answer are: Do people with RA who complete the intervention with a peer coach have lower levels of anxiety and/or depression at 6 months from baseline? Do people with RA who complete the intervention with a peer coach have lower levels of anxiety and/or depression at 6 months compared to those in the control arm? Researchers will compare the peer coaching intervention to an active-control arm (where people without RA coach participants on general health and nutrition topics) to see if peer coaching works to reduce anxiety and/or depression. Participants will meet with a coach every week for 9 weeks and complete several surveys before, during and after the intervention
Recruiting
Has No Placebo
Weill Cornell Medical CollegeIris Y Navarro-Millán, MDBristol-Myers Squibb
Image of Humana Healthcare Research, Inc. in Louisville, United States.

Academic Detailing for Rheumatoid Arthritis

Any Age
All Sexes
Louisville, KY
The goal of this trial is to learn if an interactive evidence-based educational outreach visits to clinicians who prescribe biologics change prescribing of biosimilar medications. The main questions it aims to answer are: 1. Do educational outreach visits lead to a higher number of prescriptions for biosimilar versions of adalimumab? 2. Do in-person or virtual visits work better? Researchers will compare clinicians offered the educational outreach visit to those who are not offered the visit to see if there is a difference in prescribing of biosimilar versions of adalimumab instead of the original brand-name version. Participants will be offered the chance to meet with a trained clinician who will provide educational information tailored to their knowledge and attitudes on the topic. They will also be provided an educational brochure and patient educational materials.
Waitlist Available
Has No Placebo
Humana Healthcare Research, Inc. (+1 Sites)
Have you considered Prednisone Intensol clinical trials? We made a collection of clinical trials featuring Prednisone Intensol, we think they might fit your search criteria.Go to Trials
Have you considered Prednisone Intensol clinical trials? We made a collection of clinical trials featuring Prednisone Intensol, we think they might fit your search criteria.Go to Trials
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