Precedex

Schizophrenia, Agitation, Sedation + 3 more
Treatment
20 Active Studies for Precedex

What is Precedex

DexmedetomidineThe Generic name of this drug
Treatment SummaryMedetomidine is a drug used in veterinary medicine to relieve pain and induce sedation. It works by stimulating certain receptors in the body and is the racemate of Dexmedetomidine.
Precedexis the brand name
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Precedex Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Precedex
Dexmedetomidine
2004
83

Effectiveness

How Precedex Affects PatientsDexmedetomidine works by activating certain receptors in the body, reducing the activity of the sympathetic nervous system. This leads to a decrease in anesthetic and opioid needs, as well as sedation and pain relief.
How Precedex works in the bodyDexmedetomidine works by attaching to nerve receptors in the body called alpha-2 adrenoceptors. This blocks pain signals from being sent, and also lowers blood pressure and heart rate.

When to interrupt dosage

The proposed dosage of Precedex is contingent upon the declared ailment, including Cyclic Vomiting Syndrome, Mechanical Ventilation and Disease. The quantity of dosage is contingent on the technique of delivery (e.g. Injection, solution - Intravenous or Film) specified in the table below.
Condition
Dosage
Administration
Schizophrenia
, 0.1 mg/mL, 0.004 mg/mL, 0.1 mg, 0.02 mg/mL, 0.2 mg/mL, 0.18 mg, 0.12 mg
, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Film, Sublingual, Film - Sublingual
Behcet Syndrome
, 0.1 mg/mL, 0.004 mg/mL, 0.1 mg, 0.02 mg/mL, 0.2 mg/mL, 0.18 mg, 0.12 mg
, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Film, Sublingual, Film - Sublingual
Syndrome
, 0.1 mg/mL, 0.004 mg/mL, 0.1 mg, 0.02 mg/mL, 0.2 mg/mL, 0.18 mg, 0.12 mg
, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Film, Sublingual, Film - Sublingual
Agitation
, 0.1 mg/mL, 0.004 mg/mL, 0.1 mg, 0.02 mg/mL, 0.2 mg/mL, 0.18 mg, 0.12 mg
, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Film, Sublingual, Film - Sublingual
Sedation
, 0.1 mg/mL, 0.004 mg/mL, 0.1 mg, 0.02 mg/mL, 0.2 mg/mL, 0.18 mg, 0.12 mg
, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Film, Sublingual, Film - Sublingual
induction of Sedation
, 0.1 mg/mL, 0.004 mg/mL, 0.1 mg, 0.02 mg/mL, 0.2 mg/mL, 0.18 mg, 0.12 mg
, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Film, Sublingual, Film - Sublingual

Warnings

There are 20 known major drug interactions with Precedex.
Common Precedex Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Dexmedetomidine.
Aminophylline
Major
The metabolism of Aminophylline can be decreased when combined with Dexmedetomidine.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Dexmedetomidine.
Anagrelide
Major
The metabolism of Anagrelide can be decreased when combined with Dexmedetomidine.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Dexmedetomidine.
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Precedex Novel Uses: Which Conditions Have a Clinical Trial Featuring Precedex?

12 active clinical trials are currently analyzing the utility of Precedex for Sedative therapy, Anesthetic procedures and Cyclic Vomiting Syndrome.
Condition
Clinical Trials
Trial Phases
Schizophrenia
108 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 4, Phase 2, Phase 1
Sedation
2 Actively Recruiting
Not Applicable, Phase 1
Agitation
4 Actively Recruiting
Phase 3, Phase 2, Not Applicable
Syndrome
4 Actively Recruiting
Phase 2, Phase 3, Not Applicable
induction of Sedation
0 Actively Recruiting
Behcet Syndrome
1 Actively Recruiting
Not Applicable

Precedex Reviews: What are patients saying about Precedex?

5Patient Review
9/16/2012
Precedex for Calming of Intubated Patient by Administration of Sedative
I didn't experience any benefits from this treatment, and actually found it made me more sleepless, irritable, and nervous. Not to mention the high cost.
4.3Patient Review
1/26/2013
Precedex for Calming of Intubated Patient by Administration of Sedative
I was pretty out of it after the anesthesia wore off.
2.3Patient Review
7/1/2020
Precedex for Calming of Intubated Patient by Administration of Sedative
I was woken up abruptly by intense pain and felt nauseous afterwards.
1.7Patient Review
2/28/2010
Precedex for Calming of Intubated Patient by Administration of Sedative
I experienced severe anxiety, confusion, aggressiveness, pinpoint pupils, severe light sensitivity, nausea and tremors after taking this medication.
1.7Patient Review
11/19/2009
Precedex for Calming of Intubated Patient by Administration of Sedative
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Patient Q&A Section about precedex

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Why is Precedex preferred over propofol?

"11.2 +/- 3.4 hours, respectively).

Patients sedated with dexmedetomidine spent less time on mechanical ventilation, on average, than those sedated with propofol."

Answered by AI

What class of drug is Precedex?

"Precedex is a type of drug called a sedative. It is not known if it is safe and effective to use in children."

Answered by AI

What is Precedex used to treat?

"Precedex is a medication that is indicated for use in sedating patients who are on a ventilator and receiving treatment in an intensive care setting. This medication is to be used starting on May 1, 2022."

Answered by AI

Why is Precedex used in ICU?

"Dexmedetomidine can help sedate patients while still allowing them to be responsive, and may shorten the amount of time they need mechanical ventilation and experience delirium while in the ICU."

Answered by AI

Clinical Trials for Precedex

Have you considered Precedex clinical trials? We made a collection of clinical trials featuring Precedex, we think they might fit your search criteria.
Have you considered Precedex clinical trials? We made a collection of clinical trials featuring Precedex, we think they might fit your search criteria.
Have you considered Precedex clinical trials? We made a collection of clinical trials featuring Precedex, we think they might fit your search criteria.
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