Prandin

Physical Activity, Type 2 Diabetes, Diet
Treatment
4 FDA approvals
20 Active Studies for Prandin

What is Prandin

RepaglinideThe Generic name of this drug
Treatment SummaryRepaglinide is a medication used to treat non-insulin dependent diabetes (NIDDM). It belongs to a class of drugs called meglitinides that increase the release of insulin from the pancreas. Repaglinide reduces post-meal and fasting blood sugar levels and can help lower the average blood sugar levels of the last 8-10 weeks. It should be taken with meals and skipped if the meal is skipped. Repaglinide is broken down in the liver and eliminated in bile and urine. It may cause slight weight gain but it is lower than other diabetes medications and does not usually cause hyp
Prandinis the brand name
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Prandin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Prandin
Repaglinide
2000
59

Approved as Treatment by the FDA

Repaglinide, otherwise called Prandin, is approved by the FDA for 4 uses which include Diet and Type 2 Diabetes Mellitus .
Diet
Used to treat Diet in combination with Metformin
Type 2 Diabetes Mellitus
Helps manage Type 2 Diabetes Mellitus
Physical Activity
Used to treat Exercise in combination with Metformin
Type 2 Diabetes
Helps manage Type 2 Diabetes Mellitus

Effectiveness

How Prandin Affects PatientsRepaglinide helps increase insulin secretion by the pancreas in response to changes in blood sugar levels. When blood sugar is high, it triggers a process that closes off potassium channels in cell membranes and opens up calcium channels, allowing calcium ions to enter the cell and stimulate the release of insulin granules. Repaglinide works by blocking the potassium channels, which helps increase insulin secretion when blood sugar is low.
How Prandin works in the bodyRepaglinide is a drug that works to reduce postmeal blood sugar levels. Unlike other diabetic medications, repaglinide needs glucose present in order to do its job. It helps boost the body's response to glucose, but won't do anything at all unless glucose is present. This means it's best for controlling postmeal blood sugar levels, but won't help with fasting blood sugar levels. Repaglinide also only affects pancreatic beta cells, so there are no side effects on other organs like the heart or thyroid.

When to interrupt dosage

The quantity of Prandin is contingent upon the diagnosed state, including Diet, Physical Activity and Type 2 Diabetes. The dosage likewise fluctuates per the mode of delivery (e.g. Tablet or Tablet - Oral) laid out in the table below.
Condition
Dosage
Administration
Physical Activity
, 0.5 mg, 2.0 mg, 1.0 mg, 2.0 mg/mg, 1.0 mg/mg
Tablet, , Oral, Tablet - Oral, Pill - Oral, Pill
Diet
, 0.5 mg, 2.0 mg, 1.0 mg, 2.0 mg/mg, 1.0 mg/mg
Tablet, , Oral, Tablet - Oral, Pill - Oral, Pill
Type 2 Diabetes
, 0.5 mg, 2.0 mg, 1.0 mg, 2.0 mg/mg, 1.0 mg/mg
Tablet, , Oral, Tablet - Oral, Pill - Oral, Pill

Warnings

There are 20 known major drug interactions with Prandin.
Common Prandin Drug Interactions
Drug Name
Risk Level
Description
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Repaglinide.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Repaglinide.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Repaglinide.
Erlotinib
Major
The metabolism of Erlotinib can be decreased when combined with Repaglinide.
Fluorouracil
Major
The metabolism of Fluorouracil can be decreased when combined with Repaglinide.
Prandin Toxicity & Overdose RiskThe lethal dose for rats is higher than 1 gram per kilogram of body weight.
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Prandin Novel Uses: Which Conditions Have a Clinical Trial Featuring Prandin?

196 active studies are presently being conducted to determine the effectiveness of Prandin in Diet, Physical Activity and the management of Type 2 Diabetes.
Condition
Clinical Trials
Trial Phases
Type 2 Diabetes
177 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1
Diet
5 Actively Recruiting
Not Applicable, Phase 1
Physical Activity
35 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Early Phase 1

Prandin Reviews: What are patients saying about Prandin?

5Patient Review
9/12/2010
Prandin for Type 2 Diabetes Mellitus
I experienced chest pain, back pain, and palpitation when taking this drug in combination with glimepiride. These symptoms stopped when I discontinued the medication.
5Patient Review
6/1/2013
Prandin for Type 2 Diabetes Mellitus
I've been on this treatment for a little over two years now. I haven't had any significant side effects, other than feeling low blood sugar levels on the occasions when I forget to eat after taking the medication. My A1C was 6.3, but I also exercise regularly and have a good diet and control my weight. For me, insulin is like the bogeyman, so I work hard to avoid having to take it.
5Patient Review
11/3/2011
Prandin for Type 2 Diabetes Mellitus
Prandin has been really effective in lowering my blood sugar, though the initial week was quite uncomfortable due to digestive issues. Another downside is that I've started putting on weight, so I may have to stop taking it if I can't get the pounds off.
5Patient Review
11/6/2012
Prandin for Type 2 Diabetes Mellitus
Prandin has been going very well for me, except for the awful bloating I've been experiencing in my stomach. It's gotten to the point where it actually hurts. Has anybody else had this issue?
5Patient Review
4/2/2011
Prandin for Type 2 Diabetes Mellitus
I've been taking Prandin for 16 years with excellent results. I started with 1.5mg and increased to 3.5mg over time. Suddenly, I started getting low blood sugar reactions [glucose level ~60]. Now I only take 1 pill of 1/2mg at dinner, eat anything and my blood always reads good. Are there any records of diabetes curing itself like this? Could some other medical condition be affecting my body's insulin production? Is this a miracle?
View All Reviews
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Patient Q&A Section about prandin

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the side effects of Prandin?

"Side effects from taking Benicar may include: low blood sugar, nausea, diarrhea, headache, back pain, joint pain, or cold symptoms such as a stuffy nose, sneezing, and sore throat."

Answered by AI

What class of drugs is Prandin?

"PRANDIN is an oral diabetes medication that helps control blood sugar levels. It belongs to a class of drugs called glinides."

Answered by AI

Is Prandin the same as metformin?

"Glucophage is the primary medication used to regulate blood sugar and lower the mortality risk associated with diabetes. A small number of people may experience digestive issues as a side effect of the medication. Prandin is a medication that rapidly lowers blood sugar, and is most effective around mealtimes."

Answered by AI

What is Prandin used for?

"It is used in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. This medication works by stimulating the body to produce more insulin."

Answered by AI

Clinical Trials for Prandin

Have you considered Prandin clinical trials? We made a collection of clinical trials featuring Prandin, we think they might fit your search criteria.
Have you considered Prandin clinical trials? We made a collection of clinical trials featuring Prandin, we think they might fit your search criteria.
Have you considered Prandin clinical trials? We made a collection of clinical trials featuring Prandin, we think they might fit your search criteria.
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