What is Polymyxin B Sulfate
TrimethoprimThe Generic name of this drug
Treatment SummaryTrimethoprim is an antibiotic used to treat urinary tract infections. It works by blocking a bacterial enzyme that helps the bacteria produce DNA, which leads to the bacteria's death. Trimethoprim is often used in combination with sulfamethoxazole, but can also be used on its own. It is structurally similar to pyrimethamine, another antibiotic used to treat infections caused by parasites.
Septrais the brand name
Polymyxin B Sulfate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Septra
Trimethoprim
1973
343
Approved as Treatment by the FDA
Trimethoprim, also called Septra, is approved by the FDA for 15 uses including Urinary tract infection and susceptible Enteritis infectious caused by Shigella sonnei .Urinary tract infection
Used to treat Urinary Tract Infection caused by susceptible bacteria in combination with Sulfamethoxazole
susceptible Enteritis infectious caused by Shigella sonnei
Used to treat susceptible Enteritis infectious caused by Shigella sonnei in combination with Sulfamethoxazole
Immunocompromised
Used to treat Immunocompromised in combination with Sulfamethoxazole
Genus Pneumocystis
Used to treat risk of Pneumocystis jiroveci pneumonia (PCP) in combination with Sulfamethoxazole
Pneumocystis Jirovecii Pneumonia
Used to treat Pneumocystis Jirovecii Pneumonia in combination with Sulfamethoxazole
Diarrhea
Used to treat susceptible Travelers' Diarrhea caused by Enterotoxigenic E. Coli (ETEC) Infection in combination with Sulfamethoxazole
Fluid replacement therapy
Used to treat Fluid replacement therapy in combination with Sulfamethoxazole
Shigellosis
Used to treat Dysentery, Bacillary in combination with Sulfamethoxazole
Otitis Media
Used to treat Acute Otitis Media caused by susceptible bacteria in combination with Sulfamethoxazole
Brucellosis
Used to treat Brucellosis in combination with Rifampicin
Electrolyte replacement
Used to treat Electrolyte replacement in combination with Sulfamethoxazole
Cholera
Used to treat susceptible Cholera in combination with Sulfamethoxazole
Nocardiosis
Used to treat Nocardiosis in combination with Sulfamethoxazole
Bronchitis
Used to treat Acute Exacerbation of Chronic Bronchitis (AECB) caused by susceptible bacteria in combination with Sulfamethoxazole
susceptible Enteritis infectious caused by Shigella flexneri
Used to treat susceptible Enteritis infectious caused by Shigella flexneri in combination with Sulfamethoxazole
Effectiveness
How Polymyxin B Sulfate Affects PatientsTrimethoprim helps fight bacterial infections by blocking an essential step in the creation of bacterial proteins and nucleic acids. It is effective against some gram-negative bacteria and certain types of _Staphylococcus_. Sometimes bacteria can become resistant to trimethoprim, either by changing their cell wall, overproducing an enzyme, or making a resistant form of the enzyme. Taking trimethoprim can very rarely cause blood disorders like low platelet count or low white blood cell count. Signs like fever, sore throat, and pale skin may happen before the blood disorder develops. To make sure this drug will work, local antibiotic
How Polymyxin B Sulfate works in the bodyTrimethoprim works to kill bacteria by stopping them from making the proteins and nucleic acids they need to survive. It does this by blocking an enzyme in the process of making these molecules. When used alone, trimethoprim can only stop bacteria from reproducing, but when combined with sulfamethoxazole, the two work together to actually kill the bacteria. This combination blocks two steps in the process of making proteins and nucleic acids, making it much more effective than trimethoprim alone.
When to interrupt dosage
The proposed measure of Polymyxin B Sulfate is contingent upon the determined condition, for example Urinary tract infection, Immunocompromised and Pneumocystis Jirovecii Pneumonia. The dosage also varies as indicated by the delivery approach (e.g. Tablet - Oral or Tablet) listed in the table following.Condition
Dosage
Administration
Pneumocystis Jirovecii Pneumonia
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Fluid replacement therapy
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Electrolyte replacement
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Immunocompromised
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Urinary tract infection
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Urinary tract infection
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Bacterial conjunctivitis
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Nocardiosis
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Blepharoconjunctivitis caused by susceptible bacteria
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Genus Pneumocystis
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Bronchitis
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
bacterial blepharitis caused by susceptible bacteria
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
susceptible Enteritis infectious caused by Shigella flexneri
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Cholera
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Diarrhea
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Otitis Media
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
susceptible Enteritis infectious caused by Shigella sonnei
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Shigellosis
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Brucellosis
, 80.0 mg, 40.0 mg, 9.0 mg/mL, 16.0 mg/mL, 1.0 mg/mL, 50.0 mg/mL, 8.0 mg/mL, 160.0 mg, 40.0 mg/mL, 20.0 mg, 200.0 mg, 100.0 mg, 90.0 mg, 1.6 mg, 0.16 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Warnings
Polymyxin B Sulfate has eight contraindications and should not be combined with any of the situations outlined in the table below.Polymyxin B Sulfate ContraindicationsCondition
Risk Level
Notes
Toxoplasma Infections
Do Not Combine
unable to monitor renal function
Do Not Combine
Disease
Do Not Combine
hepatic damage
Do Not Combine
Megaloblastic anemia caused by Folate deficiency
Do Not Combine
history of immune thrombocytopenia caused by trimethoprim and/or sulfonamide therapy
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Trimethoprim may interact with Toxoplasma Infections
Severe Hypersensitivity Reactions
Do Not Combine
Trimethoprim may interact with Toxoplasma Infections
Common Polymyxin B Sulfate Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The excretion of Abemaciclib can be decreased when combined with Trimethoprim.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Trimethoprim.
Cisplatin
Major
The serum concentration of Cisplatin can be increased when it is combined with Trimethoprim.
Clofarabine
Major
The serum concentration of Clofarabine can be increased when it is combined with Trimethoprim.
Dalfampridine
Major
The serum concentration of Dalfampridine can be increased when it is combined with Trimethoprim.
Polymyxin B Sulfate Toxicity & Overdose RiskIn mice and rats, the lowest toxic dose of trimethoprim is 2764 mg/kg and greater than 5300 mg/kg, respectively. If someone takes a higher dose than 1 gram, they may feel nausea, vomiting, dizziness, headaches, mental depression, confusion, or bone marrow issues. To treat this, supportive care and stomach pumping should be given. Increasing the acidity of the urine may help rid the body of the drug and hemodialysis can also be used, though it is not very effective.
Polymyxin B Sulfate Novel Uses: Which Conditions Have a Clinical Trial Featuring Polymyxin B Sulfate?
8 active clinical trials are currently underway to assess the utility of Polymyxin B Sulfate in treating Shigella flexneri-induced Enteritis, Bacterial-induced Blepharoconjunctivitis and Diarrhea.Condition
Clinical Trials
Trial Phases
Fluid replacement therapy
0 Actively Recruiting
Diarrhea
0 Actively Recruiting
Immunocompromised
3 Actively Recruiting
Phase 3, Phase 1
susceptible Enteritis infectious caused by Shigella flexneri
0 Actively Recruiting
Blepharoconjunctivitis caused by susceptible bacteria
0 Actively Recruiting
Bronchitis
0 Actively Recruiting
Brucellosis
0 Actively Recruiting
Pneumocystis Jirovecii Pneumonia
1 Actively Recruiting
Phase 3
susceptible Enteritis infectious caused by Shigella sonnei
0 Actively Recruiting
bacterial blepharitis caused by susceptible bacteria
0 Actively Recruiting
Electrolyte replacement
0 Actively Recruiting
Nocardiosis
0 Actively Recruiting
Shigellosis
4 Actively Recruiting
Phase 2, Phase 1
Urinary tract infection
0 Actively Recruiting
Otitis Media
0 Actively Recruiting
Urinary tract infection
0 Actively Recruiting
Cholera
0 Actively Recruiting
Bacterial conjunctivitis
0 Actively Recruiting
Genus Pneumocystis
0 Actively Recruiting
Polymyxin B Sulfate Reviews: What are patients saying about Polymyxin B Sulfate?
5Patient Review
9/20/2020 I had conjunctivitis with blurry vision for four days, then I started taking this medication. I am at almost 100% recovery after 48 hours. Very pleased.
5Patient Review
10/7/2017 Though this medication is intended for children, it can be used on adults with similar reactions such as itching, swelling and pain.
5Patient Review
12/1/2017 This treatment was very easy to use and I didn't experience any pain at all.
4.3Patient Review
8/31/2017 It took a little longer to work than I would have liked, but it did the job perfectly. There was some redness in my eye for a few days afterwards, but that cleared up within a week.
2.7Patient Review
11/14/2019 Ever since my daughter started using this medication, she's been complaining of more burning and stinging in her eyes. She's also having difficulty seeing.
2.7Patient Review
11/25/2018 I've been using this medication for five days now, and I'm still experiencing itchy eyes and dry, blotchy skin around my eyes. This product hasn't worked well for me so far.
2.3Patient Review
9/5/2017 Three days in and my vision seems to have gotten worse. I'm missing work as a result, which is extremely frustrating. I'll be calling the doctor today for something else entirely.
2Patient Review
9/2/2020 Unfortunately, I had really adverse reactions to this medication. Burning, itching, blurred vision, and redness were all problems I experienced shortly after using the drops. These reactions were far from mild.
2Patient Review
6/14/2018 The sulfuric acid in this medication caused burning around my eyes. I had to get a different prescription which cleared the infection in five days.
2Patient Review
2/19/2018 The burning and itching got so bad after just three days of using this drug that I had to stop. It was horrible and did nothing to help my pink eye. Avoid this treatment at all cost.
2Patient Review
3/5/2018 I've been on this medication for two days now and have yet to see any improvement.
1.7Patient Review
2/7/2020 Unfortunately, after using this treatment for just two days, my eyes became more irritated. They were swollen and red, itchy, and crusty.
1.3Patient Review
8/24/2017 My eyes felt incredibly irritated after using this product for just a few days.
1Patient Review
7/24/2019 This pink eye medication is terrible. If anything, it made my symptoms worse. Avoid if you can.
1Patient Review
9/5/2020 I had an allergic reaction to this that led to burning and itching all over my body.
1Patient Review
7/24/2019 This pink eye medication is awful. My eyes are more itchy and irritated than before, and it doesn't help at all. It just makes the Pink Eye worse by drying out my eyes.
Patient Q&A Section about polymyxin b sulfate
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How long does polymyxin take to work for pink eye?
"If your pink eye is caused by bacteria, it will improve within 24-48 hours of taking antibiotics. If it is caused by a virus, it may take a few days to more than a week to resolve."
Answered by AI
What are the side effects of polymyxin eye drops?
"Please seek medical help if you experience any of the following symptoms: severe eye pain, swelling, or redness; crusting or drainage (which may be signs of infection); swelling or redness of your eyelids; or new or worsening symptoms."
Answered by AI
What is polymyxin B sulfate drops used for?
"This medicine is a combination of two antibiotics, polymyxin B and trimethoprim, and is used to treat eye infections, including acute bacterial conjunctivitis and blepharoconjunctivitis. This medicine works by killing the bacteria or preventing their growth."
Answered by AI
Is polymyxin B sulfate used for pink eye?
"Polymyxin B and trimethoprim ophthalmic combination are used to treat bacterial infections of the eye, including conjunctivitis (pinkeye; infection of the membrane that covers the outside of the eyeball and the inside of the eyelid) or blepharoconjunctivitis (infection of the membrane that covers the outside of the eyelid and the inner surface of the eyelid)."
Answered by AI