Periogard

Mucositis, Chronic Pain, Eczema + 89 more

Treatment

3 FDA approvals

20 Active Studies for Periogard

What is Periogard

Chlorhexidine

The Generic name of this drug

Treatment Summary

Chlorhexidine is a powerful antiseptic and antimicrobial drug used to treat infections on the skin and mouth. It is made up of two 4-chlorophenyl rings and two biguanide groups connected by a central hexamethylene chain. Chlorhexidine has the ability to fight off bacteria, viruses, and yeast. It was first developed in the UK in the 1950s and was later brought to the US in the 1970s.

Hibiclens

is the brand name

image of different drug pills on a surface

Periogard Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Hibiclens

Chlorhexidine

1976

229

Approved as Treatment by the FDA

Chlorhexidine, also called Hibiclens, is approved by the FDA for 3 uses such as Dental Cavity and High Risk .

Dental Cavity

Used to treat Dental Cavity in combination with Sodium fluoride

High Risk

Used to treat High Risk in combination with Sodium fluoride

Dental Caries

Used to treat Dental Cavity in combination with Sodium fluoride

Effectiveness

How Periogard Affects Patients

Chlorhexidine is an antimicrobial that can kill both virus, bacteria, and fungus. It's strength depends on the concentration used - lower concentrations slow down the growth of microorganisms, while higher concentrations kill them. Chlorhexidine has the ability to stick to surfaces, such as teeth, which helps it fight off microorganisms. However, this can cause staining of the teeth if used for long periods of time. People with allergies to chlorhexidine may experience anaphylaxis.

How Periogard works in the body

Chlorhexidine works by damaging the cell membranes of bacteria and other microbes. It does this by attaching to the negative charges found in cell membranes. This reaction weakens the cells, allowing their contents to leak out and eventually causing death. Depending on the concentration of chlorhexidine, the action can be either bacteriostatic (slowing down growth) or bactericidal (killing the bacteria).

When to interrupt dosage

The advised dosage of Periogard is contingent upon the determined circumstances, for example Wound, Oral Hygiene and Ringworm. The amount of dosage is contingent upon the method of administration (e.g. Rinse or Cream; Kit; Ointment; Solution) specified in the table below.

Condition

Dosage

Administration

Difficulty Swallowing

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Ringworm

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Tonsillitis

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Topical Antisepsis

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Minor Surgical Procedures

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Disinfection

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Antisepsis

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Dental Plaque

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Antisepsis

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Glossitis

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Sore Throat

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Gum Disease

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Eye

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Leg Ulcer

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Obstetrics

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Wound

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Cystoscopy

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Catheterization

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Pressure Ulcer

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Pharmacotherapy

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Warnings

Periogard has one contraindication and should not be amalgamated with the conditions outlined in the following table.

Periogard Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Chlorhexidine may interact with Pulse Frequency

There are 1 known major drug interactions with Periogard.

Common Periogard Drug Interactions

Drug Name

Risk Level

Description

Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen

Major

The therapeutic efficacy of Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen can be decreased when used in combination with Chlorhexidine.

Periogard Toxicity & Overdose Risk

The highest dose of chlorhexidine that is toxic to mice is greater than 5g/kg. If a small child consumes 1-2 ounces of chlorhexidine, they may experience stomach upset, nausea, and intoxication. Treatment should be given to reduce symptoms and supportive measures should be used. If a child has ingested more than 4 ounces of chlorhexidine or displays signs of intoxication, medical attention should be sought.

image of a doctor in a lab doing drug, clinical research

Periogard Novel Uses: Which Conditions Have a Clinical Trial Featuring Periogard?

35 active clinical trials are currently exploring the potential of Periogard to provide Disinfection, Augment Breast Milk Production and Mitigate Tissue Damage.

Condition

Clinical Trials

Trial Phases

Eczema

0 Actively Recruiting

Chronic Pain

124 Actively Recruiting

Not Applicable, Phase 2, Phase 4, Phase 3, Early Phase 1, Phase 1

Antisepsis

0 Actively Recruiting

Stomach Diseases

0 Actively Recruiting

recurrent Oral fungal infection

0 Actively Recruiting

Topical Antisepsis

0 Actively Recruiting

Dental Scaling

0 Actively Recruiting

Dental Caries

0 Actively Recruiting

Neurodermatitis

0 Actively Recruiting

Cystoscopy

0 Actively Recruiting

Injury Throat

0 Actively Recruiting

Hoarseness

0 Actively Recruiting

Minor Surgical Procedures

0 Actively Recruiting

Disinfection

0 Actively Recruiting

Mucositis

1 Actively Recruiting

Not Applicable

oral infections

1 Actively Recruiting

Not Applicable

Endoscopy

0 Actively Recruiting

High Risk

0 Actively Recruiting

Post-chemotherapy

0 Actively Recruiting

oral lesions

0 Actively Recruiting

Periogard Reviews: What are patients saying about Periogard?

5

Patient Review

7/8/2013

Periogard for Inflammation of the Gums

I lost five teeth due to bone loss and gum disease, but this treatment has really helped me keep my gums healthy. I've been using it for a while now and my dentist is always impressed with how healthy my gums are. If I had known about this sooner, I could have prevented the loss of those teeth.

5

Patient Review

2/1/2016

Periogard for Inflammation of the Gums

I found this medication to be very helpful for reducing pain, bleeding and tenderness in my gums. I don't have to use it every day anymore, which is great.

3

Patient Review

8/18/2011

Periogard for Inflammation of the Gums

I've been using this mouth rinse for a little over two days to help with inflammation and sore gums after a dental cleaning. So far, I haven't noticed any difference. Additionally, I have been feeling strange since using it; I have a heavy feeling in my chest that radiates into my stomach. It lasts for a couple hours and is really uncomfortable. Not to mention the horrible taste! I am supposed to use it for another week, but at this point, I'm not sure if I should continue because of how it's making me feel.

2.7

Patient Review

5/10/2013

Periogard for Inflammation of the Gums

I noticed some marginal improvements in my gum health after using Periogard, but then I started to see stains on my teeth. From that experience, I have stopped using the product.

2.7

Patient Review

10/13/2022

Periogard for Inflammation of the Gums

PerioGuard toothpaste caused me to develop a really unpleasant dry mouth that nothing could relieve. Once I stopped using the toothpaste, the dry mouth gradually went away and is now totally fine.

2.3

Patient Review

6/29/2014

Periogard for Inflammation of the Gums

While this oral rinse did help with the bleeding around one tooth, the side effects were not worth it. My tongue was left sore, my mouth dry and I had a persistent metallic taste that lasted for days. If you haven't opened it yet, take it back!
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about periogard

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Periogard over the counter?

"PerioGard is a prescription-strength anti-microbial rinse that is used to treat gingivitis and promote the healing of inflamed gums. This product is only available through a prescription from a healthcare provider."

Answered by AI

What is Periogard used for?

"This medication is used to treat gingivitis in conjunction with regular tooth brushing and flossing. Chlorhexidine is an antimicrobial agent that is known to be effective against bacteria and fungi."

Answered by AI

Do you rinse after Periogard?

"Do not rinse your mouth with water or other mouthwashes immediately after using Periogard. Periogard may leave an unpleasant taste in your mouth, but rinsing it away will reduce the effectiveness of the medication."

Answered by AI

How long should you use Periogard?

"PerioGard should be used twice daily, once in the morning and once at night. To use, rinse for 30 seconds after brushing your teeth."

Answered by AI

Clinical Trials for Periogard

Image of UC Davis Medical Center in Sacramento, United States.

Antibiotic Carriers for Breast Reconstruction

18+
Female
Sacramento, CA

Infections after tissue expander breast reconstruction can lead to pain, additional surgeries, and loss of the reconstruction. This study will compare two types of antibiotic carriers used during surgery to help lower the risk of infection. One carrier is a non-absorbable PMMA disc, and the other is an absorbable antibiotic bead. Both release antibiotics directly into the breast pocket after surgery. About 100 patients will be randomly assigned to receive one of these two carriers at the time of tissue expander placement. After surgery, small samples of fluid around the tissue expander will be collected during routine clinic visits. These samples will be tested to measure how much antibiotic is present over time. The study will also track infections, tissue expander loss, and other complications during the first 90 days after surgery. The goal is to learn how much antibiotic each carrier delivers and whether one method is more effective at preventing infection.

Waitlist Available
Has No Placebo

UC Davis Medical Center

Ara A Salibian, MD

Image of AltaSciences, Inc in Cypress, United States.

SBS-147 Safety Study

18 - 55
All Sexes
Cypress, CA

This study is part of the HEAL Initiative supported by the NIH. The purpose of this study is to learn how safe the study drug, SBS-147, is and how people's bodies respond to and process it. Researchers will also look for any side effects that may occur when taking SBS-147. Some participants will receive SBS-147, and others will receive a placebo, which looks the same but does not contain any medicine. This helps researchers fairly compare results. The study includes two parts: Single-Dose Group, where Participants receive SBS-147 or placebo one time. Multiple-Dose Group, where Participants receive SBS-147 or placebo once or twice daily for 7 days.

Phase 1
Waitlist Available

AltaSciences, Inc

Jeff Reich, MD

Sparian Biosciences, Inc

Have you considered Periogard clinical trials?

We made a collection of clinical trials featuring Periogard, we think they might fit your search criteria.
Go to Trials

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We made a collection of clinical trials featuring Periogard, we think they might fit your search criteria.
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Image of University of Virginia in Charlottesville, United States.

Pharyngeal Wall Augmentation for Speech Disorder

18+
All Sexes
Charlottesville, VA

Some head and neck cancer survivors develop velopharyngeal dysfunction (VPD), a problem with closure between the soft palate and throat that can cause nasal-sounding speech, food or liquid leaking into the nose, difficulty swallowing, and reduced quality of life. This study aims to better understand VPD in this population and to evaluate whether pharyngeal wall augmentation (plumping up the back wall of the throat) can improve speech and swallowing. Participants will undergo a multidisciplinary assessment including physical examination, flexible nasolaryngoscopy, speech recording and acoustic analysis, nasometry, clinical swallowing evaluation, and fiberoptic endoscopic evaluation of swallowing (FEES). Aim 1: Determine the prevalence, severity, and functional impact of VPD in head and neck cancer survivors. Aim 2: Assess the feasibility and usefulness of advanced diagnostic tools for VPD. The investigators hypothesize that high nasalance scores (\>1 SD above normal) will accurately predict VPD with at least 75% positive predictive value and will correlate with worse communication-related quality of life (CPIB). The investigators also hypothesize that participants with VPD will have more pharyngeal residue or nasal regurgitation on FEES, and that these findings will be associated with lower swallowing-related quality of life (SWAL-QOL). Aim 3: Evaluate the effectiveness of pharyngeal wall augmentation injections for improving speech intelligibility and swallowing function. The investigators expect that this treatment will lead to measurable changes in both objective assessments and patient-reported outcomes. The results will help improve diagnosis and management of VPD in head and neck cancer survivors.

Recruiting
Has No Placebo

University of Virginia

Vanessa Torrecillas, MD

Image of University of Toronto in Toronto, Canada.

SALI-10 Oral Probiotics for Gum Disease

18 - 70
All Sexes
Toronto, Canada

Gingivitis is among the most prevalent oral diseases worldwide, affecting an estimated 50-90% of adults. It is a reversible condition primarily caused by microbial plaque accumulation on teeth and gingival surfaces, which triggers inflammation. Standard care emphasizes plaque reduction through oral hygiene, and research shows gingivitis can be reversed once hygiene resumes. The classic experimental gingivitis (EG) model developed in 1965 by Löe and Silness demonstrated the direct link between plaque buildup and gingival inflammation, further confirming that gingival health can be restored after resuming proper care. Microbial ecology shifts are central to gingivitis pathogenesis. In health, the oral microbiome is dominated by gram-positive Streptococcus species. With plaque accumulation, microbial communities transition to gram-negative periopathogens such as Porphyromonas, Tannerella, Treponema, and Prevotella. This dysbiosis provokes heightened inflammation, tissue damage, and, in susceptible individuals, progression to periodontitis. Individual variability in the inflammatory response has been associated with differences in the presence and activity of beneficial streptococci. Certain strains of Streptococcus salivarius produce lantibiotics called salivaricins-polycyclic antimicrobial peptides containing lanthionine residues. Salivaricins inhibit oral pathogens and have been investigated for their antimicrobial and probiotic properties, particularly in the context of rising antibiotic resistance. Probiotic S. salivarius strains isolated from healthy individuals have demonstrated safety and antimicrobial potential in previous studies, supporting their use in preventing oral and respiratory infections. A strain of S. salivarius designated SALI-10 produces a lantibiotic, Salivaricin 10, and is being evaluated as a candidate for gingivitis prevention. This strain is hypothesized to (1) help stabilize populations of beneficial streptococci during plaque accumulation, (2) competitively inhibit periopathogens such as Porphyromonas and Prevotella, and (3) suppress the dysbiotic shift toward gram-negative dominance. By contributing to microbial balance and reducing inflammatory triggers, SALI-10 may support resilient host-microbe interactions associated with gingival health. This approach may offer a dual antimicrobial and microbiome-stabilizing strategy with relevance to gingivitis management and longer-term periodontal health.

Phase 2
Recruiting

University of Toronto

Dr. Michael Goldberg, MDM

Ostia Sciences

Have you considered Periogard clinical trials?

We made a collection of clinical trials featuring Periogard, we think they might fit your search criteria.
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