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What is Perforomist
FormoterolThe Generic name of this drug
Treatment SummaryFormoterol is an inhalable medication used to treat COPD and asthma. It helps to relax and open the airways, providing relief from symptoms. It works quickly (within 2-3 minutes) and lasts for up to 12 hours. It is available on its own or in combination with other medications such as corticosteroids and long-acting muscarinic antagonists. It was approved by the FDA in 2001.
Foradilis the brand name
Perforomist Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Foradil
Formoterol
2001
37
Effectiveness
How Perforomist Affects PatientsFormoterol helps open up the airways in the lungs and makes it easier to breathe. It works quickly (around 2-3 minutes) and can last up to 12 hours. People with asthma should not take this alone, as it may increase the risk of death due to asthma.
How Perforomist works in the bodyFormoterol is a drug that helps open up airways and reduce swelling in the lungs. It works by targeting specific receptors in the lungs that cause airways to narrow. By activating these receptors, it increases the production of a molecule that helps relax and widen airway muscles, while also reducing the release of substances that cause inflammation.
When to interrupt dosage
The quantity of Perforomist is contingent upon the identified illness, including Bronchial Asthma, Bronchoconstriction and Asthma. The dosage fluctuates according to the delivery mode (e.g. Solution - Respiratory (inhalation) or Aerosol) featured in the table below.Condition
Dosage
Administration
Chronic Obstructive Pulmonary Disease
, 0.012 mg, 0.005 mg, 0.02 mg/mL, 0.0048 mg, 0.0045 mg, 0.009 mg, 0.012 mg/pump actuation, 0.0058 mg/pump actuation, 0.006 mg/pump actuation, 0.005 mg/pump actuation
, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Powder, metered, Powder, metered - Respiratory (inhalation), Aerosol, Aerosol - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation)
Asthma
, 0.012 mg, 0.005 mg, 0.02 mg/mL, 0.0048 mg, 0.0045 mg, 0.009 mg, 0.012 mg/pump actuation, 0.0058 mg/pump actuation, 0.006 mg/pump actuation, 0.005 mg/pump actuation
, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Powder, metered, Powder, metered - Respiratory (inhalation), Aerosol, Aerosol - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation)
Bronchoconstriction
, 0.012 mg, 0.005 mg, 0.02 mg/mL, 0.0048 mg, 0.0045 mg, 0.009 mg, 0.012 mg/pump actuation, 0.0058 mg/pump actuation, 0.006 mg/pump actuation, 0.005 mg/pump actuation
, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Powder, metered, Powder, metered - Respiratory (inhalation), Aerosol, Aerosol - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation)
maintenance therapy
, 0.012 mg, 0.005 mg, 0.02 mg/mL, 0.0048 mg, 0.0045 mg, 0.009 mg, 0.012 mg/pump actuation, 0.0058 mg/pump actuation, 0.006 mg/pump actuation, 0.005 mg/pump actuation
, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Powder, metered, Powder, metered - Respiratory (inhalation), Aerosol, Aerosol - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation)
Asthma, Exercise-Induced
, 0.012 mg, 0.005 mg, 0.02 mg/mL, 0.0048 mg, 0.0045 mg, 0.009 mg, 0.012 mg/pump actuation, 0.0058 mg/pump actuation, 0.006 mg/pump actuation, 0.005 mg/pump actuation
, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Powder, metered, Powder, metered - Respiratory (inhalation), Aerosol, Aerosol - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation)
Chronic Obstructive Airway Disease
, 0.012 mg, 0.005 mg, 0.02 mg/mL, 0.0048 mg, 0.0045 mg, 0.009 mg, 0.012 mg/pump actuation, 0.0058 mg/pump actuation, 0.006 mg/pump actuation, 0.005 mg/pump actuation
, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Powder, metered, Powder, metered - Respiratory (inhalation), Aerosol, Aerosol - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation)
Asthma
, 0.012 mg, 0.005 mg, 0.02 mg/mL, 0.0048 mg, 0.0045 mg, 0.009 mg, 0.012 mg/pump actuation, 0.0058 mg/pump actuation, 0.006 mg/pump actuation, 0.005 mg/pump actuation
, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Powder, metered, Powder, metered - Respiratory (inhalation), Aerosol, Aerosol - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation)
Chronic Obstructive Airway Disease
, 0.012 mg, 0.005 mg, 0.02 mg/mL, 0.0048 mg, 0.0045 mg, 0.009 mg, 0.012 mg/pump actuation, 0.0058 mg/pump actuation, 0.006 mg/pump actuation, 0.005 mg/pump actuation
, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Powder, metered, Powder, metered - Respiratory (inhalation), Aerosol, Aerosol - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation)
Pulmonary Disease, Chronic Obstructive
, 0.012 mg, 0.005 mg, 0.02 mg/mL, 0.0048 mg, 0.0045 mg, 0.009 mg, 0.012 mg/pump actuation, 0.0058 mg/pump actuation, 0.006 mg/pump actuation, 0.005 mg/pump actuation
, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Powder, Powder - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Powder, metered, Powder, metered - Respiratory (inhalation), Aerosol, Aerosol - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation)
Warnings
Perforomist has four contraindications. It should be avoided when dealing with any of the conditions stipulated in the following table.Perforomist ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Formoterol may interact with Pulse Frequency
Status Asthmaticus
Do Not Combine
Asthma
Do Not Combine
Status Asthmaticus
Do Not Combine
Common Perforomist Drug Interactions
Drug Name
Risk Level
Description
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Formoterol.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Formoterol.
Clomipramine
Major
The metabolism of Clomipramine can be decreased when combined with Formoterol.
Cyclophosphamide
Major
The metabolism of Cyclophosphamide can be decreased when combined with Formoterol.
Dacomitinib
Major
The metabolism of Dacomitinib can be decreased when combined with Formoterol.
Perforomist Toxicity & Overdose RiskThe toxic dose of formoterol in rats has been found to be 3130mg/kg. Potential symptoms of overdose include chest pain, high or low blood pressure, rapid heartbeat, nervousness, headache, tremors, seizures, and dry mouth. Lab tests may show low potassium levels, high blood sugar, and acidosis. Treatment of an overdose should focus on providing supportive care and monitoring the patient's heart rate. It may also be helpful to use a medication that blocks certain types of adrenergic stimulation.
Perforomist Novel Uses: Which Conditions Have a Clinical Trial Featuring Perforomist?
251 active studies are currently investigating the effectiveness of Perforomist in managing Chronic Obstructive Pulmonary Disease (COPD), Moderate to Severe COPD and Chronic Obstructive Airways Disease.Condition
Clinical Trials
Trial Phases
Chronic Obstructive Pulmonary Disease
85 Actively Recruiting
Phase 3, Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 4
Chronic Obstructive Airway Disease
6 Actively Recruiting
Not Applicable, Phase 4
maintenance therapy
0 Actively Recruiting
Chronic Obstructive Airway Disease
0 Actively Recruiting
Pulmonary Disease, Chronic Obstructive
0 Actively Recruiting
Asthma, Exercise-Induced
1 Actively Recruiting
Not Applicable
Asthma
1 Actively Recruiting
Phase 4
Bronchoconstriction
0 Actively Recruiting
Asthma
88 Actively Recruiting
Phase 4, Early Phase 1, Phase 2, Not Applicable, Phase 1, Phase 3
Perforomist Reviews: What are patients saying about Perforomist?
5Patient Review
11/1/2013 At first, I had a burning sensation in the back of my throat. But after five days of use, my symptoms got worse. I started having a tight chest and severe wheezing. It became difficult to breathe, so I went to see a doctor.
5Patient Review
3/10/2013 This medication has really helped me out and made a big difference in my life.
5Patient Review
10/10/2010 The only side effects I experience are dry mouth, losing my voice occasionally, and sometimes feeling off-balance.
5Patient Review
12/23/20075Patient Review
10/23/2008Patient Q&A Section about perforomist
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the generic for Perforomist?
"Both Perforomist and Brovana are brand-name drugs and there are no generic forms currently available."
Answered by AI
Is Perforomist a steroid?
"Formoterol relaxes the muscles that allow air to enter the lungs, rather than being a steroid. It is classified as a long-acting beta-agonist (LABA)."
Answered by AI
What are the side effects of Perforomist?
"You may experience some, all, or none of the following side effects while taking Perforomist: shakiness (tremor), nausea, headache, nervousness, dizziness, dry mouth, trouble sleeping (insomnia), anxiety, back pain, muscle cramps, sore throat, cough, stuffy nose, skin rash, itching, or changes in your voice."
Answered by AI
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