Oxandrin

Chronic Pain, Obesity, weight gain therapy + 3 more
Treatment
10 FDA approvals
20 Active Studies for Oxandrin

What is Oxandrin

OxandroloneThe Generic name of this drug
Treatment SummaryA synthetic hormone with the ability to increase muscle growth and strength as well as promote male characteristics.
Oxandrinis the brand name
image of different drug pills on a surface
Oxandrin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Oxandrin
Oxandrolone
2005
16

Approved as Treatment by the FDA

Oxandrolone, also known as Oxandrin, is approved by the FDA for 10 uses like Obesity and Osteoarthritis (OA) .
Obesity
Osteoarthritis (OA)
Helps manage Osteoarthritis (OA)
Weight Gain
weight gain therapy
Pain
Helps manage Pain
Amino acid catabolism disorder
Helps manage Amino acid catabolism disorder
Chronic Pain
Helps manage Pain
Osteoarthritis
Helps manage Osteoarthritis (OA)
Amino Acid Metabolism, Inborn Errors
Helps manage Amino acid catabolism disorder
corticosteroid therapy
Helps manage corticosteroid therapy

Effectiveness

How Oxandrin Affects PatientsOxandrolone is a type of anabolic steroid used to help people who have lost a lot of weight due to surgery, infection, or injury gain weight. It is also used to counteract the muscle-weakening effects of taking corticosteroids for a long time and to reduce pain from weakening bones caused by osteoporosis. Anabolic steroids are a synthetic form of testosterone.
How Oxandrin works in the bodyOxandrolones attach to androgen receptors in specific areas of the body.

When to interrupt dosage

The suggested dosage of Oxandrin depends upon the diagnosed condition, which may include Obesity, Amino acid catabolism disorder and corticosteroid therapy. The amount of dosage will vary, contingent upon the method of delivery provided in the below table.
Condition
Dosage
Administration
Chronic Pain
, 2.5 mg, 10.0 mg
, Tablet, Oral, Tablet - Oral
weight gain therapy
, 2.5 mg, 10.0 mg
, Tablet, Oral, Tablet - Oral
Amino Acid Metabolism, Inborn Errors
, 2.5 mg, 10.0 mg
, Tablet, Oral, Tablet - Oral
corticosteroid therapy
, 2.5 mg, 10.0 mg
, Tablet, Oral, Tablet - Oral
Osteoarthritis
, 2.5 mg, 10.0 mg
, Tablet, Oral, Tablet - Oral
Obesity
, 2.5 mg, 10.0 mg
, Tablet, Oral, Tablet - Oral

Warnings

Oxandrin has five contraindications and should not be utilized alongside the conditions specified in the following table.Oxandrin Contraindications
Condition
Risk Level
Notes
Breast Cancer
Do Not Combine
Hypercalcemia
Do Not Combine
Breast Cancer
Do Not Combine
Nephrosis
Do Not Combine
Breast
Do Not Combine
There are 20 known major drug interactions with Oxandrin.
Common Oxandrin Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Oxandrolone.
Cabozantinib
Major
The metabolism of Cabozantinib can be decreased when combined with Oxandrolone.
Capecitabine
Major
The metabolism of Capecitabine can be decreased when combined with Oxandrolone.
Cyclophosphamide
Major
The metabolism of Cyclophosphamide can be decreased when combined with Oxandrolone.
Dabrafenib
Major
The metabolism of Dabrafenib can be decreased when combined with Oxandrolone.
Oxandrin Toxicity & Overdose RiskThe lowest toxic dose of oxandrolone when taken orally in mice and dogs has been found to be greater than 5,000mg/kg.
image of a doctor in a lab doing drug, clinical research

Oxandrin Novel Uses: Which Conditions Have a Clinical Trial Featuring Oxandrin?

211 active clinical trials are currently being conducted to assess the effectiveness of Oxandrin as a weight gain therapy, Obesity treatment and Osteoarthritis (OA) remedy.
Condition
Clinical Trials
Trial Phases
Amino Acid Metabolism, Inborn Errors
3 Actively Recruiting
Phase 1, Phase 2
weight gain therapy
0 Actively Recruiting
Obesity
14 Actively Recruiting
Not Applicable, Phase 2, Phase 3
Osteoarthritis
0 Actively Recruiting
corticosteroid therapy
0 Actively Recruiting
Chronic Pain
129 Actively Recruiting
Not Applicable, Phase 4, Phase 2, Phase 3, Early Phase 1, Phase 1

Oxandrin Reviews: What are patients saying about Oxandrin?

4.7Patient Review
1/28/2009
Oxandrin for Metabolic Process Which Breaks Down Substances in the Body
This treatment is effective on its own, and has the same effect as if taken with marinol.
3.7Patient Review
2/16/2009
Oxandrin for Inherited Disorder of Continuing Episodes of Swelling
This medicine has been helpful in managing my hereditary angioedema.

Patient Q&A Section about oxandrin

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is oxandrin used for?

"This medication helps people regain weight that they have lost because of certain medical conditions. These include surgery, chronic infection, trauma, and the long-term use of corticosteroid medication such as hydrocortisone or prednisone. The medication is also used to relieve bone pain that is caused by bone loss, such as osteoporosis."

Answered by AI

Is oxandrin a controlled substance?

"Oxandrolone is a controlled substance that is classified as a non-narcotic drug."

Answered by AI

What is the generic name for oxandrin?

"Oxandrin® oral tablets contain 2.5 mg or 10 mg of the anabolic steroid oxandrolone."

Answered by AI

What does oxandrolone do to your body?

"Oxandrolone is a medication that belongs to a class of hormones called androgenic hormones. This medication works by increasing the amount of protein the body makes. More muscle and increased body weight occur when there is more protein."

Answered by AI

Clinical Trials for Oxandrin

Image of Vanderbilt University Medical Center in Nashville, United States.

Lidocaine Infusions for Postoperative Pain

18+
All Sexes
Nashville, TN
The goal of this single-center, pragmatic, randomized, blinded, placebo-controlled trial is to evaluate the impact of intravenous (IV) lidocaine within the existing Enhanced Recovery After Surgery (ERAS)program on outcomes in patients after major abdominal surgery. The main questions the trial aims to answer are: The primary hypothesis is that utilization of IV lidocaine as part of a perioperative multimodal pain regimen will result in a reduction in hospital Case Mix Index-Adjusted Resource Length of Stay (CARLOS). The secondary hypotheses are that lidocaine infusion will result in a reduction in total inpatient opioid consumption (oral morphine milligram equivalents, oMMEs) and pain scores, and improved surgical outcomes (including return of bowel function, ileus, nausea, rapid responses called, surgical site infections, and ICU transfers), while also having minimal incidence of side effects (including double/blurry vision, tinnitus, sedation, and adverse events requiring early cessation).
Phase 4
Waitlist Available
Vanderbilt University Medical CenterDanial Shams, MD
Image of Baylor College of Medicine/Texas Children's Hospital in Austin, United States.

Guided Imagery Therapy for Abdominal Pain

7 - 12
All Sexes
Austin, TX
Chronic abdominal pain is common among children, and the majority of cases are attributed to functional abdominal pain disorders. One approach to treating these disorders is by using psychological therapies. This clinical trial aims to see how well pre-recorded guided imagery therapy sessions help children's abdominal pain when delivered via a mobile application (app) on a smartphone or tablet. Participants will complete a baseline abdominal pain and stooling diary to determine eligibility, as well as other surveys. Eligible participants will be given access to the guided imagery therapy mobile application. This intervention asks participants to listen to a 10- to 15-minute GIT session 5 out of 7 days per week for 8 weeks, in addition to their usual care for their abdominal pain. Then, participants will complete another abdominal pain and stooling diary, along with other psychometric surveys, at the end of this intervention period. Participants will also collect another diary and surveys 3 months post-treatment.
Waitlist Available
Has No Placebo
Baylor College of Medicine/Texas Children's Hospital (+1 Sites)
Have you considered Oxandrin clinical trials? We made a collection of clinical trials featuring Oxandrin, we think they might fit your search criteria.Go to Trials
Image of University Hospitals Cleveland Medical Center in Cleveland, United States.

Erector Spinae Plane Block for Pain

21 - 75
All Sexes
Cleveland, OH
As per usual care for spine surgery, participants will have their back cleaned with alcohol and a needle will be placed using ultrasound for the ESP block. Through the needle, a small catheter will be placed in the participants back and the needle removed. Approximately one hour prior to the start of surgery, a numbing medication (ropivacaine, similar to Novocaine) in combination with dexmedetomidine (a pain medicine that is used in nerve block and that is not a narcotic) and contrast dye (iohexol) will be injected through the catheter. Participants will then go through the QST procedure (test of buzzing sensation and temperature sensation through pads applied to their skin) to assess the numb areas and then head to the operating room. In the operating room, the catheter will be removed after the surgeon obtains baseline CT scan images of the spine. Once surgery is completed, investigators will record pain scores over the next four days in the hospital and the amount of pain medication needed for controlling pain related to the surgery.
Recruiting
Has No Placebo
University Hospitals Cleveland Medical CenterSalim Hayek, MD
Have you considered Oxandrin clinical trials? We made a collection of clinical trials featuring Oxandrin, we think they might fit your search criteria.Go to Trials
Image of BC Children's Hospital in Vancouver, Canada.

Digital Media for Anxiety in Children

5 - 23
All Sexes
Vancouver, Canada
The goal of this clinical trial is to learn whether different forms of media (2D, 360, or 360 in virtual reality) have different impacts on pre-procedural anxiety and post-procedural pain in children. The main questions it aims to answer are: Does one type (and richness) of media reduce pre-procedural anxiety and post-procedural pain more than another type of media? For example, will learning about an upcoming procedure by watching a 360 video in virtual reality reduce pre-procedural anxiety more than learning about the same upcoming procedure by watching it in a 2D video or 360 video? The second question is whether watching a 360 video in VR about an upcoming procedure more effective in reducing pre-procedural anxiety and post-procedural pain compared to the 2D video or the 360 video without VR groups for specific procedures? For example, is watching an explanation of a procedure in VR always more effective in reducing pre-procedural anxiety and post-procedural pain, or is it procedure specific (i.e., watching a video about surgery preparation is more effective in VR, but for cast removal it doesn't matter whether participants learn about their procedure viewed through VR, 360 video, or 2D)?
Recruiting
Has No Placebo
BC Children's Hospital
Image of Active Aging Research Team, Robert H. N. Ho Research Centre in Vancouver, Canada.

Choose to Move Replacement Ready for Osteoarthritis

18+
All Sexes
Vancouver, Canada
Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada. Recently, the investigators adapted CTM for the \>14000 people in BC who are on surgical waitlists for total knee replacement or total hip replacement (TKR/THR) for osteoarthritis (OA). The primary goal of this observational study is to learn if the adapted program, Choose to Move Replacement Ready (CTM-RR), is feasible to deliver to people with hip and/or knee osteoarthritis who are on surgical waitlists for TKR/THR. Participants who enrol in CTM-RR will answer online survey questions about the program and about their physical activity, mobility, pain, function, quality of life, willingness to undergo surgery, overall perception of their joint condition, psychosocial health, self-efficacy, social isolation, loneliness, and sedentary time. CTM-RR activity coaches will also answer online survey questions about the program. CTM-RR participants, activity coaches, and referral partners will also participate in interviews about the program.
Recruiting
Has No Placebo
Active Aging Research Team, Robert H. N. Ho Research CentreHeather A. McKay, PhD
Have you considered Oxandrin clinical trials? We made a collection of clinical trials featuring Oxandrin, we think they might fit your search criteria.Go to Trials
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