Nitrostat

prophylaxis of Angina pectoris, Congestive Heart Failure, Chest Pain + 10 more
Treatment
20 Active Studies for Nitrostat

What is Nitrostat

NitroglycerinThe Generic name of this drug
Treatment SummaryNitroglycerin is a medication used to treat chest pain and high blood pressure. It was first approved in 2000 and is now made by Pfizer and other companies in different forms like a spray, tablets, an intravenous form, an extended-release form, and a transdermal form. In addition to treating angina, nitroglycerin can also be used as an ointment to relieve the pain of anal fissures. The rectal ointment form of nitroglycerin was approved by the FDA in 1955.
Nitroglycerinis the brand name
image of different drug pills on a surface
Nitrostat Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Nitroglycerin
Nitroglycerin
1981
182

Effectiveness

How Nitrostat Affects PatientsNitroglycerin helps to relax the walls of blood vessels and increases blood flow to the heart. This reduces the amount of work the heart needs to do and improves symptoms of chest pain. However, taking nitroglycerin for a long time can make it less effective, as the body gets used to it. This is because the enzyme that activates nitroglycerin is blocked. Nitroglycerin tolerance can also lead to other issues, such as a pro-oxidant effect, reduced blood vessel function, and increased sensitivity to medicines that constrict blood vessels.
How Nitrostat works in the bodyNitroglycerin helps to relax and open up blood vessels, allowing more blood to flow. It does this by converting to nitric oxide in the cells, which starts a chain reaction. Nitric oxide activates an enzyme that turns a molecule in the body into cyclic GMP, which relaxes the muscles in the blood vessels and increases blood flow. It also seems to target receptors that help control how much salt and water are in your body.

When to interrupt dosage

The amount of Nitrostat is contingent upon the diagnosed illness, including Coronary Artery Spasm, induction of Uterine relaxation and Anal Fissure. The dosage also depends on the technique of administration (e.g. Tablet or Tablet - Oral) depicted in the table beneath.
Condition
Dosage
Administration
induction of Intraoperative Hypotension
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
prophylaxis of Angina pectoris
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Congestive Heart Failure
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Chest Pain
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Coronary Artery Disease (CAD)
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Hypotension
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Anal Fissure
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Hypertensive disease
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Myocardial Infarction
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
insufficient response to beta-blockers
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
nitroglycerin
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Pain
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous
Angina Attacks
, 160.0 mg, 20.0 mg, 40.0 mg, 60.0 mg, 80.0 mg, 120.0 mg, 0.02 mg/mg, 0.1 mg/hour, 0.2 mg/hour, 0.4 mg/hour, 0.6 mg/hour, 2.5 mg, 9.0 mg, 6.5 mg, 0.4 mg, 0.25 mg/hour, 0.5 mg/hour, 1.0 mg/hour, 1.5 mg/hour, 0.004 mg/mg, 0.3 mg, 5.0 mg/mL, 37.4 mg, 20.8 mg, 50.0 mg, 1.0 mg, 2.0 %, 0.6 mg, 75.0 mg, 54.0 mg, 36.0 mg, 18.0 mg, 25.0 mg, 2.6 mg, 100.0 mg, 0.1 mg/mL, 0.2 mg/mL, 0.4 mg/mL, 0.0004 mg/mg, 18.0 mg/[USP'U], 12.5 mg, 1.0 mg/mL, 0.8 mg/hour, 7.2 mg/cm2, 0.4 mg/pump actuation, 6.0 mg/cm2
, Transdermal, Patch, Patch - Transdermal, Topical, Ointment, Ointment - Topical, Oral, Capsule, Capsule - Oral, Sublingual, Tablet - Sublingual, Tablet, Spray, Spray - Oral, Tablet - Oral, Aerosol, metered, Aerosol, metered - Sublingual, Spray, metered, Spray, metered - Oral, Ointment - Rectal, Rectal, Spray, metered - Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Film, extended release, Film, extended release - Transdermal, Patch, extended release, Patch, extended release - Transdermal, Liquid, Liquid - Intravenous, Solution, Solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Buccal, Tablet, extended release - Buccal, Injection, Injection - Intravenous, Powder, Powder - Sublingual, Transmucosal, Aerosol, spray, Aerosol, spray - Transmucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous

Warnings

Nitrostat Contraindications
Condition
Risk Level
Notes
pericardial tamponade
Do Not Combine
Pulse Frequency
Do Not Combine
Hypovolemic Shock
Do Not Combine
Anemia
Do Not Combine
Pick Disease of Heart
Do Not Combine
Pulse Frequency
Do Not Combine
Acute Circulatory Failure
Do Not Combine
Intracranial Hypertension
Do Not Combine
Cardiomyopathy, Restrictive
Do Not Combine
Myocardial Infarction
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Nitroglycerin may interact with Pulse Frequency
There are 20 known major drug interactions with Nitrostat.
Common Nitrostat Drug Interactions
Drug Name
Risk Level
Description
Amediplase
Major
The therapeutic efficacy of Amediplase can be decreased when used in combination with Nitroglycerin.
Amifostine
Major
Nitroglycerin may increase the hypotensive activities of Amifostine.
Desmoteplase
Major
The therapeutic efficacy of Desmoteplase can be decreased when used in combination with Nitroglycerin.
Reteplase
Major
The therapeutic efficacy of Reteplase can be decreased when used in combination with Nitroglycerin.
Riociguat
Major
Nitroglycerin may increase the hypotensive activities of Riociguat.
Nitrostat Toxicity & Overdose RiskThe toxic dose of nitroglycerin in rats is 105 mg/kg when taken orally, and 23.2 mg/kg when taken intravenously. Symptoms of overdosing on nitroglycerin include low blood pressure, a severe headache, dizziness, palpitations, flushed skin, nausea, vomiting, shortness of breath, a slow pulse, confusion, and possible death due to lack of circulation. Rarely, one may experience a decreased level of oxygen in the blood (methemoglobinemia). There is no known antidote to an overdose and treatment involves supportive measures such as elevating the lower limbs and providing oxygen
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Nitrostat Novel Uses: Which Conditions Have a Clinical Trial Featuring Nitrostat?

38 active investigations are presently assessing the potential of Nitrostat to prevent Gastroesophageal variceal hemorrhage, Hypotension and Congestive Heart Failure.
Condition
Clinical Trials
Trial Phases
Congestive Heart Failure
23 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1
Myocardial Infarction
0 Actively Recruiting
Anal Fissure
0 Actively Recruiting
Chest Pain
6 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 4
insufficient response to beta-blockers
0 Actively Recruiting
Hypotension
1 Actively Recruiting
Early Phase 1
Coronary Artery Disease (CAD)
1 Actively Recruiting
Not Applicable
induction of Intraoperative Hypotension
0 Actively Recruiting
prophylaxis of Angina pectoris
0 Actively Recruiting
nitroglycerin
0 Actively Recruiting
Hypertensive disease
0 Actively Recruiting
Angina Attacks
0 Actively Recruiting
Pain
0 Actively Recruiting

Nitrostat Reviews: What are patients saying about Nitrostat?

5Patient Review
7/13/2009
Nitrostat for Angina
5Patient Review
1/13/2010
Nitrostat for Chronic Heart Failure
5Patient Review
8/25/2011
Nitrostat for Angina
This drug is really effective in a short amount of time. I have COPD and use it before physical activity to help with my breathing. In the 35 days that I've been using it, some days I don't need it at all.
5Patient Review
10/23/2011
Nitrostat for Angina Pectoris Prevention
Worked well after two doses, but caused a nasty headache. According to the cardiologist I saw, this is apparently normal.
5Patient Review
5/17/2012
Nitrostat for Angina
So far, one tablet has been working great for me.
5Patient Review
7/10/2013
Nitrostat for Angina
This pill completely removed my pain in just three minutes- it was amazing!
5Patient Review
7/29/2010
Nitrostat for Angina
This treatment really helped me. I'm grateful for modern medicine.
5Patient Review
11/28/2016
Nitrostat for Angina Pectoris Prevention
The results of this medication are great, but the high price tag is due to a monopoly on its production.
5Patient Review
7/27/2015
Nitrostat for Angina
I've found this medication to be effective in treating occasional chest pain and angina attacks. Sometimes I have had to take a second one for the same episode, but my doctor says no more than 3.
5Patient Review
5/31/2018
Nitrostat for Angina
NitroStat is extremely effective against the pain of coronary spasms. I've taken up to three pills in a short period of time and found that the pain fades to a tolerable level within minutes.
4.7Patient Review
9/27/2011
Nitrostat for Heart Attack
I was having chest pains and took one tablet of this medication. I then went to the hospital, where they told me I was having a heart attack and needed surgery.
4.3Patient Review
10/13/2011
Nitrostat for Angina
I accidentally swallowed the pill, but it was still effective.
4.3Patient Review
11/30/2014
Nitrostat for Angina
Nitrostat is very effective at quickly reducing the intensity of my angina pain, though it doesn't completely eliminate it. I worry about taking a second pill since it might drop my blood pressure too low; however, if the pain becomes unbearable, I would take another one and call for medical assistance.
3Patient Review
3/15/2010
Nitrostat for Osteoporosis

Patient Q&A Section about nitrostat

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is nitrostat and nitroglycerin the same?

"This can help to lower your blood pressure. Nitroglycerin is used to treat chest pain (angina).

Nitrostat (nitroglycerin) is a type of nitrate that works to relax your blood vessels and lower your blood pressure. Nitroglycerin is used to treat chest pain (angina)."

Answered by AI

What are the side effects of nitrostat?

"You may experience headache, weakness, dizziness, lightheadedness, nausea, and flushing as your body adjusts to this medication."

Answered by AI

What type of drug is nitrostat?

"NITROSTAT is a medication used to treat angina, which is a type of chest pain caused by restricted blood flow to the heart."

Answered by AI

How does nitrostat make you feel?

"Nitroglycerin relaxes smooth muscle and blood vessels, increasing the amount of blood and oxygen that reaches the heart, and reduces chest pain."

Answered by AI

Clinical Trials for Nitrostat

Have you considered Nitrostat clinical trials? We made a collection of clinical trials featuring Nitrostat, we think they might fit your search criteria.
Have you considered Nitrostat clinical trials? We made a collection of clinical trials featuring Nitrostat, we think they might fit your search criteria.
Have you considered Nitrostat clinical trials? We made a collection of clinical trials featuring Nitrostat, we think they might fit your search criteria.
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