Mental Stress for Heart Failure
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this study is to investigate whether acute stress can precipitate congestive heart failure (CHF) exacerbation in patients with CHF.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. However, if you use chronic opioids, you cannot participate in the trial.
Is mental stress safe for people with heart failure?
How does this treatment for heart failure differ from other treatments?
This treatment focuses on managing mental stress, which is unique because it addresses psychological factors that can worsen heart failure symptoms. Unlike traditional treatments that primarily target physical symptoms, this approach considers stress as a modifiable factor that can improve quality of life and outcomes for heart failure patients.23678
What data supports the effectiveness of the treatment Mental Stress, Psychological Stress, Emotional Stress, Anxiety for heart failure?
Who Is on the Research Team?
Rachel Lampert, MD
Principal Investigator
Yale University
Are You a Good Fit for This Trial?
This trial is for heart failure patients over 18 with a Cardiomems PAP monitor. It's not for those on chronic opioids, with disabilities preventing assessments, other conditions affecting PA pressures, physical limitations to participate, non-compliance with PAP monitoring or Class IV heart failure.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Laboratory Component
Participants undergo a laboratory mental stress protocol including resting, relaxation, stress, and recovery periods with PAP and blood pressure assessments.
Field Component
Participants complete daily PAP assessments and eDiary-based EMA for six months, with additional evening assessments for one month.
Follow-up
Clinical outcomes are determined through review of the Cardiomems Merlin database and medical record review.
What Are the Treatments Tested in This Trial?
Interventions
- Mental Stress
Find a Clinic Near You
Who Is Running the Clinical Trial?
Yale University
Lead Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Collaborator