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What is Navane
ThiothixeneThe Generic name of this drug
Treatment SummaryThiothixene is an antipsychotic medication that works similarly to other antipsychotic drugs. It is used to treat mental health conditions such as schizophrenia and bipolar disorder.
Navaneis the brand name
Navane Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Navane
Thiothixene
1967
50
Approved as Treatment by the FDA
Thiothixene, also known as Navane, is approved by the FDA for 1 uses which include Schizophrenia .Schizophrenia
Helps manage Schizophrenia
Effectiveness
How Navane Affects PatientsThiothixene is an older type of antipsychotic drug that is not used as often today as newer drugs like risperidone. It belongs to a group of drugs called thioxanthene series and shares certain chemical and pharmacological similarities to other antipsychotics. However, it is not as effective as the newer medications.
How Navane works in the bodyThiothixene works by blocking certain receptors in the brain. It works on dopamine receptors to reduce symptoms of psychosis, serotonin receptors to reduce anxiety, depression and aggression, histamine receptors to cause sedation, weight gain and lower blood pressure, alpha receptors to reduce symptoms of Parkinson's and muscarinic receptors to cause dry mouth, blurred vision and difficulty urinating.
When to interrupt dosage
The recommended measure of Navane is contingent upon the confirmed condition. The portion of dosage fluctuates, based on the technique of delivery (e.g. Capsule or Capsule - Oral) featured in the table beneath.Condition
Dosage
Administration
Schizophrenia
, 1.0 mg, 2.0 mg, 5.0 mg, 10.0 mg, 20.0 mg, 5.0 mg/mL
, Capsule, Oral, Capsule - Oral, Tablet - Oral, Tablet, Solution, concentrate, Solution, concentrate - Oral
Warnings
Navane ContraindicationsCondition
Risk Level
Notes
Comatose
Do Not Combine
Shock
Do Not Combine
Disease
Do Not Combine
Mental Depression
Do Not Combine
Common Navane Drug Interactions
Drug Name
Risk Level
Description
Amisulpride
Major
Thiothixene may increase the antipsychotic activities of Amisulpride.
Azelastine
Major
Thiothixene may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Deutetrabenazine
Major
The risk or severity of adverse effects can be increased when Thiothixene is combined with Deutetrabenazine.
Ethanol
Major
Thiothixene may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Hydroxyzine
Major
The risk or severity of QTc prolongation can be increased when Thiothixene is combined with Hydroxyzine.
Navane Toxicity & Overdose RiskSigns of an overdose on Xanax include confusion, trouble swallowing, dizziness, drowsiness, a tilted head, low blood pressure, muscle twitching, stiff muscles, excessive saliva, shaking, difficulty walking, and weakness.
Navane Novel Uses: Which Conditions Have a Clinical Trial Featuring Navane?
Condition
Clinical Trials
Trial Phases
Schizophrenia
175 Actively Recruiting
Not Applicable, Phase 3, Phase 2, Early Phase 1, Phase 4, Phase 1
Navane Reviews: What are patients saying about Navane?
5Patient Review
5/28/2019 Navane has been an absolute godsend. I don't know how I would have lived without it these past 40 years.
5Patient Review
10/26/20075Patient Review
1/30/2009 I sleep very well when I take this drug at night. It's also a lot less expensive than some of the newer drugs on the market.
5Patient Review
3/24/2009 I was having a lot of anxiety and struggling to focus, plus crying spells and involuntary muscle movements. This treatment really helped me get those under control.
5Patient Review
10/2/2010 I've been using this medication to treat my bipolar disorder for twenty years. I find it highly effective with few side effects. It's much better than many of the newer psychiatric medications on the market.
5Patient Review
7/11/2010 Missing a dose of this medication would cause my hallucinations to come back, but Risperdal has completely eliminated that problem for me. I'm on the generic brand and it works just as well as its more expensive counterpart.
4.3Patient Review
1/1/2013 This medication was really effective for my bi-polar disorder. However, I did experience some weight gain and increased prolactin levels.
4.3Patient Review
3/12/2011 I've been on Navane for decades now, and it's the only thing that keeps me stable. I know it's not perfect, but it's better than anything else I've tried.
3.7Patient Review
5/4/2010 I've been on Navane for a couple years now. It's not perfect, but it does the job. That said, be careful; this medication caused me to put on a lot of weight. Additionally, you have to be careful about what other medications you take while on Navane because they tend to interact.
2.7Patient Review
7/19/2009 I was given this medication for psychosis. After a few weeks, I had extremely adverse reactions including shaking, loss of all emotion, depression, and suicide thoughts. I was 36 years old at the time. I was put on the drug again at age 50. It was fine for a few weeks but then I had the same problems, with less shaking.
1.3Patient Review
4/8/2010 I've been taking this medication because I can't afford the more expensive option, risperdal.
Patient Q&A Section about navane
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Navane used for?
"Thiothixene, also known as Navane, is an antipsychotic medication used to treat schizophrenia and other conditions with psychotic features, including bipolar disorder. Thiothixene is rarely used today to treat psychosis."
Answered by AI
Is Navane discontinued?
"The Navane brand name has been discontinued in the U.S. However, if generic versions of this product have been approved by the FDA, there may be generic equivalents available."
Answered by AI
Is Navane an atypical antipsychotic?
"The following is a paraphrased version of the text above:
Navane (Thiothixene) is a typical antipsychotic drug. It is used to treat schizophrenia and other psychotic disorders. It works by blocking dopamine receptors in the brain."
Answered by AI
What drug class is Navane?
"These drugs are also called “typical antipsychotics.”
Navane is a member of the class of drugs known as antipsychotics, or first-generation drugs. These drugs are sometimes referred to as "typical antipsychotics.""
Answered by AI