Curcumin Supplements for Arthritis
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to determine if two different curcumin supplements can alleviate joint discomfort in individuals who have experienced it for at least six months. Researchers seek to understand if these supplements can enhance participants' perceptions of joint comfort and overall quality of life. Participants will take each supplement and a placebo (a pill with no active ingredient) without knowing which is which, while wearing a fitness tracker. This trial suits those with mild to moderate joint discomfort who do not have major joint diseases or conditions affecting walking. As an unphased trial, it offers participants the chance to contribute to valuable research that could improve joint comfort solutions.
Do I have to stop taking my current medications for the trial?
Yes, you will need to stop taking certain medications, such as blood thinners, opioid painkillers, topical joint treatments, and NSAIDs like ibuprofen or naproxen, as they are not allowed during the study.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Studies have shown that curcumin, a natural ingredient in turmeric, is generally safe for people. Research indicates it may help with conditions like arthritis, inflammation, and pain. The FDA considers curcumin "generally recognized as safe," meaning it is unlikely to cause harm when used as directed.
In studies with arthritis patients, curcumin did not cause serious side effects. Some people might experience mild stomach upset, but this is rare. Overall, curcumin is well-tolerated and usually does not cause significant problems.
These findings apply to both types of curcumin tested in the trial. Participants can feel confident about the safety of these curcumin supplements based on existing research.12345Why are researchers excited about this trial's treatments?
Researchers are excited about using curcumin supplements for arthritis because, unlike standard treatments like NSAIDs or corticosteroids, curcumin is a natural compound found in turmeric. Curcumin is believed to reduce inflammation through a different mechanism by inhibiting certain molecules known as cytokines, which are responsible for promoting inflammation. Additionally, curcumin has antioxidant properties, potentially providing dual benefits in managing arthritis symptoms with fewer side effects. This natural approach offers promise as a complementary or alternative option for those seeking relief from arthritis without the risks associated with long-term use of conventional medications.
What evidence suggests that this trial's treatments could be effective for arthritis?
This trial will compare two different curcumin supplements for arthritis. Studies have shown that curcumin can reduce pain and improve joint function. Research indicates that curcumin supplements significantly lower pain levels in people with knee osteoarthritis compared to a placebo. Other studies found that turmeric products, which contain curcumin, effectively ease knee osteoarthritis pain when used alone. Curcumin has also reduced inflammation and pain in arthritis patients. Overall, these findings suggest that curcumin supplements may improve joint comfort and reduce pain.23678
Who Is on the Research Team?
Adam Payne, CEO, MBA
Principal Investigator
Ultra Botanica LLC
Are You a Good Fit for This Trial?
Adults with self-reported joint discomfort, possibly due to arthritis, are eligible for this trial. They must be willing to take supplements, wear a fitness tracker, and complete questionnaires. Details on specific inclusion or exclusion criteria are not provided.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Placebo Run-In
Participants receive a placebo to establish baseline measurements
Treatment Phase 1
Participants take the first curcumin supplement twice daily for 30 days
Washout
Participants undergo a 7-day washout period between treatments
Treatment Phase 2
Participants take the second curcumin supplement twice daily for 30 days
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Supplement 1
- Supplement 2
Find a Clinic Near You
Who Is Running the Clinical Trial?
Ultra Botanica LLC
Lead Sponsor