Minocycline Hydrochloride

Rocky Mountain Spotted Fever, Relapsing Fever, Trachoma + 22 more

Treatment

5 Active Studies for Minocycline Hydrochloride

What is Minocycline Hydrochloride

Minocycline

The Generic name of this drug

Treatment Summary

Minocycline is an antibiotic that was developed in 1966 and approved by the FDA in 1971. It is more effective at fighting bacteria than earlier tetracycline antibiotics, as it has modifications to the D ring of its molecules. Minocycline is effective against both gram-negative and gram-positive bacteria.

Minocin

is the brand name

image of different drug pills on a surface

Minocycline Hydrochloride Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Minocin

Minocycline

1990

305

Effectiveness

How Minocycline Hydrochloride Affects Patients

Minocycline is an antibiotic that stops bacteria from making proteins, which in turn kills the bacteria. It is usually taken 2-4 times a day, with a maximum of 400mg per day. People should be aware of potential side effects such as tooth and bone development issues, gastrointestinal problems, changes in the nervous system, and increased pressure around the brain.

How Minocycline Hydrochloride works in the body

Tetracyclines work by preventing proteins from forming in bacterial cells. They enter the cells through special channels and dissolve in the cytoplasm. Once inside, they stop amino acids from binding to the ribosome, which is responsible for creating proteins. This stops bacteria from making new proteins, and ultimately kills it.

When to interrupt dosage

The recommended dosage of Minocycline Hydrochloride is contingent upon the determined condition, such as Periodontitis, Rickettsialpox and Lymphogranuloma Venereum. The measure of dosage fluctuates, in relation to the method of application (e.g. Capsule, extended release or Tablet, film coated, extended release) specified in the table beneath.

Condition

Dosage

Administration

Gum Disease

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Campylobacter fetus

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Psittacosis

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Brucellosis

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Lymphogranuloma Venereum

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Granuloma Inguinale

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Respiratory Tract Infections

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Inflammation

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Urethritis

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Typhus, Endemic Flea-Borne

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Rickettsia Infections

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Cat-Scratch Disease

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Dental Root Planing

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Plague

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Acne Vulgaris

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Rickettsialpox

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Disease

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Rocky Mountain Spotted Fever

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Relapsing Fever

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Trachoma

, 75.0 mg, 45.0 mg, 90.0 mg, 135.0 mg, 50.0 mg, 100.0 mg, 80.0 mg, 1.0 mg, 65.0 mg, 115.0 mg, 55.0 mg, 105.0 mg, 67.5 mg, 112.5 mg, 0.04 mg/mg, 0.015 mg/mg, 1.0 mg/mg

, Oral, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, coated pellets, Capsule, coated pellets - Oral, Kit, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Powder, Powder - Oral, Topical, Aerosol, foam - Topical, Aerosol, foam

Warnings

Minocycline Hydrochloride Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Minocycline may interact with Pulse Frequency

There are 20 known major drug interactions with Minocycline Hydrochloride.

Common Minocycline Hydrochloride Drug Interactions

Drug Name

Risk Level

Description

Amdinocillin

Major

The therapeutic efficacy of Amdinocillin can be decreased when used in combination with Minocycline.

Amoxicillin

Major

The therapeutic efficacy of Amoxicillin can be decreased when used in combination with Minocycline.

Ampicillin

Major

The therapeutic efficacy of Ampicillin can be decreased when used in combination with Minocycline.

Aspoxicillin

Major

The therapeutic efficacy of Aspoxicillin can be decreased when used in combination with Minocycline.

Azidocillin

Major

The therapeutic efficacy of Azidocillin can be decreased when used in combination with Minocycline.

Minocycline Hydrochloride Toxicity & Overdose Risk

The lowest toxic dose of minocycline found in rats is 2380mg/kg, and 3600mg/kg in mice. Overdosing on minocycline may cause dizziness, nausea, and vomiting. In such an event, the drug should be stopped and the patient should be given supportive care.

image of a doctor in a lab doing drug, clinical research

Minocycline Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Minocycline Hydrochloride?

10 active trials are currently examining the therapeutic potential of Minocycline Hydrochloride in treating Psittacosis, Tularemia and other Diseases.

Condition

Clinical Trials

Trial Phases

Gum Disease

3 Actively Recruiting

Phase 3, Not Applicable

Trachoma

2 Actively Recruiting

Phase 4, Not Applicable

Lymphogranuloma Venereum

0 Actively Recruiting

Disease

0 Actively Recruiting

Psittacosis

0 Actively Recruiting

Respiratory Tract Infections

0 Actively Recruiting

Dental Scaling

0 Actively Recruiting

Typhus, Endemic Flea-Borne

0 Actively Recruiting

Acne Vulgaris

0 Actively Recruiting

Relapsing Fever

0 Actively Recruiting

Plague

0 Actively Recruiting

Cat-Scratch Disease

0 Actively Recruiting

Rocky Mountain Spotted Fever

0 Actively Recruiting

Inflammation

0 Actively Recruiting

Brucellosis

0 Actively Recruiting

Rickettsia Infections

0 Actively Recruiting

Chancroid

0 Actively Recruiting

Q Fever

0 Actively Recruiting

Conjunctivitis, Inclusion

0 Actively Recruiting

Rickettsialpox

0 Actively Recruiting

Minocycline Hydrochloride Reviews: What are patients saying about Minocycline Hydrochloride?

5

Patient Review

12/7/2018

Minocycline Hydrochloride for Acne

I had really bad rosacea on my face, and nothing I tried worked for over a year. Finally got this medication and after just three days, the rosacea was gone and hasn't come back in six months!

4.7

Patient Review

4/11/2019

Minocycline Hydrochloride for Acne

I just finished the two-month recommended treatment with this medication. I found it very successful in clearing up my mild acne; however, I did experience some adverse side effects including vaginal yeast infections and a genital skin rash.

4.3

Patient Review

3/18/2019

Minocycline Hydrochloride for Acne

My acne was completely gone within two months, and my skin's texture had improved; however, I experienced increased anxiety and depression. Once I stopped taking the medication, my acne returned slightly but my mental health problems resolved.

4

Patient Review

3/8/2021

Minocycline Hydrochloride for Acne

After using this medication for 3 months, my acne has improved significantly. The majority of my blemishes are gone and I experienced no negative side effects.

3.7

Patient Review

11/19/2019

Minocycline Hydrochloride for Acne

While this medication did clear up my acne to a greater extent, the side effects were really severe. I became incredibly emotional and sensitive, got hives and a skin rash, and just generally didn't feel happy or motivated anymore.

3.3

Patient Review

3/13/2021

Minocycline Hydrochloride for Acne

Minocycline was unfortunately not worth the abdominal pain, diarrhea, and hives I got from it. It did clear up my acne effectively, but I had to discontinue use due to how severe the side effects were.

3

Patient Review

7/6/2022

Minocycline Hydrochloride for Acne

I've been on this medication for a year, and then took a break. Recently started up again and while it's only been a month, I can tell it's working. However, there are some side effects like hives and feeling high/sensitive, but the acne-reduction is worth it to me.

2.7

Patient Review

10/16/2022

Minocycline Hydrochloride for Infection due to Nocardia Bacteria

I've been taking the medication as directed for three days now, and I'm still experiencing symptoms and a lot of pain.

2.7

Patient Review

9/16/2021

Minocycline Hydrochloride for Acne

I was prescribed this medication by my dermatologist for scalp acne. Unfortunately, it has not worked at all for that purpose; however, I have experienced every single listed side effect. This has been a very negative experience overall.

2.3

Patient Review

12/9/2020

Minocycline Hydrochloride for Acne

I experienced a lot of serious side effects from this medication, which ultimately resulted in a pseudo tumor and excess spinal fluid. I'm only 14 years old and very small (under 120lb), so I'm not the typical candidate for these sorts of problems. And unfortunately, this medication did nothing to improve my acne.

2

Patient Review

8/20/2022

Minocycline Hydrochloride for Skin Infection

Rosacea sufferers, beware of Akamin! I was directed to take two per day by my doctor, and after just over a month of use I developed a large and itchy rash on my back and arms. Be sure to do your research before trying any new treatments.

1

Patient Review

10/28/2021

Minocycline Hydrochloride for Acne

I was not given adequate warning about the possible side effects of this medication. I developed meningitis as a result and had to spend four days in the hospital. It took me over a month to recover fully, during which time my acne remained out of control.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about minocycline hydrochloride

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What skin infections does minocycline treat?

"Minocycline is an antibiotic that belongs to the class of tetracycline antibiotics. It is used to treat infections by preventing the growth and spread of bacteria. Additionally, minocycline can be used to treat acne by killing the bacteria that infects pores, and by decreases the production of a natural oily substance that contributes to the formation of acne."

Answered by AI

What are side effects of taking minocycline?

"The following are symptoms of a heart attack: black, tarry stools; blistering, peeling, or loosening of the skin; blood in the urine or stools; blurred or double vision; bulging soft spot on the head of an infant; chest pain, possibly moving to the left arm, neck, or shoulder; dizziness or lightheadedness; and eye pain."

Answered by AI

What is minocycline hydrochloride used for?

"Minocycline capsules are used to treat bacterial infections. It is also used to treat anthrax infection and other infections."

Answered by AI

How long does it take for minocycline hydrochloride to work?

"It usually takes minocycline (Minocin) 2 days to start working on an infection."

Answered by AI

Clinical Trials for Minocycline Hydrochloride

Image of University of North Carolina in Chapel Hill, United States.

BLTR vs B-RAP for Trichiasis

18+
All Sexes
Chapel Hill, NC

The primary objective of this randomized clinical trial is to determine whether repeat trichiasis surgery performed with Bevel-Rotate Advancement Procedure (B-RAP) improves surgical success compared to Bilamellar Tarsal Rotation (BLTR) among a group of 8-10 TT surgeons in Tanzania. The study aims to enroll 1,000 individuals with PTT. The primary outcome is repeat PTT within one year after surgery. Additionally, the study will assess eyelid contour abnormalities and how they change over a two-year period as well as patient reported outcomes. If this project is successful in improving surgical outcomes, it could change the approach to treating PTT globally. Individuals with trichiasis have a significantly reduced quality of life; correcting their trichiasis long-term has the potential to improve their quality of life and their family members' quality of life considerably.

Waitlist Available
Has No Placebo

University of North Carolina

Emily Gower, PhD

Image of Office of Dental Health, Department of Health and Senior Services in Jefferson City, United States.

Dental Care for Pneumonia Prevention

60 - 100
All Sexes
Jefferson City, MO

The goal of this study is to learn if dental infection control treatment delivered to older adult nursing home residents at their place of residence will result in : * improved dental health * reduced risk of pneumonia * better glucose control for diabetic patients compared to the pre-project dental and general health evaluations of residents and the pre-project facility incidence of pneumonia. Dental infection control treatment includes treating gum infections, stopping or slowing decay with fluoride, and assisting residents with effective tooth brushing and denture cleaning daily. Previous studies indicate dental infections can be inhaled and cause pneumonia or make diabetes worse. A shortage of dentists has limited care for nursing home residents. This project will allow dental hygienists and specially trained dental assistants to treat nursing home residents using telehealth methods (computers, cameras, internet, and telephone) to talk and work with dentists in different locations.

Recruiting
Has No Placebo

Office of Dental Health, Department of Health and Senior Services

Image of University of Alabame in Birmingham, United States.

Antibiotics for Gum Disease

18+
All Sexes
Birmingham, AL

Periodontitis is a bacterial inflammatory disease and antibiotic use is being empirically used as part of its treatment. However, a clinical practice guideline on periodontal treatment adjuncts published in 2015 identified weak evidence on the use of systemic antibiotics and large heterogeneity across small scale studies, suggesting that larger pragmatic clinical trials would benefit clinical decision making. This will be a prospective, randomized, placebo-controlled trial, stratified by practice and practitioner. The study will investigate the effectiveness of adjunctive antibiotics as adjunct to scaling and root planing (SRP) compared to SRP with placebo for the treatment of generalized stage II-III, grades A-C periodontitis in patient participants from National Dental PBRN practices. Periodontal data will be collected at baseline, re-evaluation (6 weeks), and final (4-12 months) study visits. Changes in periodontal clinical and patient-reported outcomes will be assessed to determine the effectiveness of SRP plus adjunctive systemic Amoxicillin / Metronidazole antibiotics (AMXM) versus SRP with Placebo.

Phase 3
Recruiting

University of Alabame

Georgios Kotsakis, DDS

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