Miglitol

Q: What are the side effects of miglitol?

<p>Diarrhea, gas, upset stomach, stomach or abdominal <a href="https://www.withpower.com/clinical-trials/pain">pain</a>, skin rash, or iron deficiency anemia are common side effects in the first few weeks of treatment as the body adjusts to this medication but these side effects usually improve with time.</p>

Physical Activity, Type 2 Diabetes, Diet

Treatment

2 FDA approvals

20 Active Studies for Miglitol

Treatment for

Physical Activity

What is Miglitol

MiglitolThe Generic name of this drug

Treatment SummaryMiglitol is an oral medication used to help manage blood sugar levels in people with type 2 diabetes. It works by preventing the digestion of complex carbohydrates into smaller sugars which can be absorbed by the body. Miglitol should be taken at the start of a meal for maximum effectiveness, and the amount of sugar it prevents depends on the types of carbohydrates in the diet. This drug works by blocking the breakdown of carbohydrates into sugars, reducing the amount of sugar in the bloodstream after a meal. Unlike other drugs in its class, miglitol is not metabolized and is instead excreted through the kidneys.

Glysetis the brand name

image of different drug pills on a surface

Miglitol Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Glyset

Miglitol

1996

Approved as Treatment by the FDA

Miglitol, also known as Glyset, is approved by the FDA for 2 uses including Type 2 Diabetes Mellitus and Type 2 Diabetes .

Type 2 Diabetes Mellitus

Helps manage Type 2 Diabetes Mellitus

Type 2 Diabetes

Helps manage Type 2 Diabetes Mellitus

Effectiveness

How Miglitol Affects PatientsMiglitol is a medication that slows down the digestion of carbohydrates. This helps to keep blood sugar levels more stable in people with Type II diabetes. Miglitol can be used in combination with other diabetes medications, such as sulfonylureas, to help control blood sugar. Additionally, miglitol can reduce the weight gain and extra insulin sensitivity that sulfonylureas can cause. It does not have any significant effect on lactase, so it should not cause lactose intolerance.

How Miglitol works in the bodyMiglitol works differently than sulfonylureas, which stimulate the release of insulin. Instead, it blocks enzymes in the small intestine that break down complex sugars into glucose. This slows down the absorption of glucose by the body and helps to reduce post-meal blood sugar levels in diabetic patients.

When to interrupt dosage

The endorsed dose of Miglitol is subject to the identified condition, including Type 2 Diabetes, Physical Activity and Diet. The amount of dosage fluctuates, as outlined by the course of delivery (e.g. Tablet, coated - Oral or Oral) detailed in the table below.

Condition

Dosage

Administration

Physical Activity

, 50.0 mg, 100.0 mg, 25.0 mg

, Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated - Oral, Tablet, film coated

Type 2 Diabetes

, 50.0 mg, 100.0 mg, 25.0 mg

, Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated - Oral, Tablet, film coated

Diet

, 50.0 mg, 100.0 mg, 25.0 mg

, Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated - Oral, Tablet, film coated

Warnings

Miglitol has nine contraindications, and its use should be abstained from when dealing with any of the conditions stated in the subsequent table.Miglitol Contraindications

Condition

Risk Level

Notes

Digestive Disorders

Do Not Combine

Pulse Frequency

Do Not Combine

Disease

Do Not Combine

Intestinal Obstruction

Do Not Combine

colonic ulceration

Do Not Combine

Crohn's Disease

Do Not Combine

Intestines

Do Not Combine

Diabetic Ketoacidosis

Do Not Combine

Capillaria philippinensis Infection

Do Not Combine

There are 20 known major drug interactions with Miglitol.

Common Miglitol Drug Interactions

Drug Name

Risk Level

Description

Ketotifen

Minor

The risk or severity of thrombocytopenia can be increased when Miglitol is combined with Ketotifen.

2,4-thiazolidinedione

Moderate

The risk or severity of hypoglycemia can be increased when Miglitol is combined with 2,4-thiazolidinedione.

AICA ribonucleotide

Moderate

The risk or severity of hypoglycemia can be increased when Miglitol is combined with AICA ribonucleotide.

AMG-222

Moderate

The risk or severity of hypoglycemia can be increased when Miglitol is combined with AMG-222.

Acetohexamide

Moderate

The risk or severity of hypoglycemia can be increased when Miglitol is combined with Acetohexamide.

Miglitol Toxicity & Overdose RiskIf you're taking miglitol, don't worry about an overdose causing low blood sugar levels. An overdose may cause an increase in gas, diarrhea, and stomach upset. However, no serious systemic reactions are expected after taking too much miglitol.

image of a doctor in a lab doing drug, clinical research

Miglitol Novel Uses: Which Conditions Have a Clinical Trial Featuring Miglitol?

196 active trials are currently assessing the potential of Miglitol to improve Diet, Type 2 Diabetes and Physical Activity outcomes.

Condition

Clinical Trials

Trial Phases

Type 2 Diabetes

177 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1

Physical Activity

35 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Early Phase 1

Diet

5 Actively Recruiting

Not Applicable, Phase 1

Miglitol Reviews: What are patients saying about Miglitol?

2Patient Review

12/9/2012

Miglitol for Type 2 Diabetes Mellitus

I was initially pleased with the results of this medication, but now I find that it gives me erectile dysfunction. This is a frustrating side effect that seems to be common among many drugs.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about miglitol

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is miglitol used for?

"Miglitol is used to lower high blood sugar levels that are caused by type 2 diabetes."

Answered by AI

When should miglitol be taken?

"Miglitol comes in the form of a tablet that is meant to be taken orally. The recommended dosage is three times a day, with the first dose being taken during the first bite of a meal. It is important to follow the directions on the prescription label carefully and to ask for clarification from a doctor or pharmacist if anything is unclear."

Answered by AI

What are the side effects of miglitol?

"Diarrhea, gas, upset stomach, stomach or abdominal pain, skin rash, or iron deficiency anemia are common side effects in the first few weeks of treatment as the body adjusts to this medication but these side effects usually improve with time."

Answered by AI

What type of medication is miglitol?

"Miglitol works by delaying the digestion of carbohydrates. It inhibits the breakdown of complex carbohydrates into glucose, which helps improve glycemic control."

Answered by AI

Clinical Trials for Miglitol

Have you considered Miglitol clinical trials? We made a collection of clinical trials featuring Miglitol, we think they might fit your search criteria.

Have you considered Miglitol clinical trials? We made a collection of clinical trials featuring Miglitol, we think they might fit your search criteria.