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What is Miglitol
MiglitolThe Generic name of this drug
Treatment SummaryMiglitol is an oral medication used to help manage blood sugar levels in people with type 2 diabetes. It works by preventing the digestion of complex carbohydrates into smaller sugars which can be absorbed by the body. Miglitol should be taken at the start of a meal for maximum effectiveness, and the amount of sugar it prevents depends on the types of carbohydrates in the diet. This drug works by blocking the breakdown of carbohydrates into sugars, reducing the amount of sugar in the bloodstream after a meal. Unlike other drugs in its class, miglitol is not metabolized and is instead excreted through the kidneys.
Glysetis the brand name
Miglitol Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Glyset
Miglitol
1996
16
Approved as Treatment by the FDA
Miglitol, also known as Glyset, is approved by the FDA for 1 uses including Type 2 Diabetes .Type 2 Diabetes
Helps manage Type 2 Diabetes Mellitus
Effectiveness
How Miglitol Affects PatientsMiglitol is a medication that slows down the digestion of carbohydrates. This helps to keep blood sugar levels more stable in people with Type II diabetes. Miglitol can be used in combination with other diabetes medications, such as sulfonylureas, to help control blood sugar. Additionally, miglitol can reduce the weight gain and extra insulin sensitivity that sulfonylureas can cause. It does not have any significant effect on lactase, so it should not cause lactose intolerance.
How Miglitol works in the bodyMiglitol works differently than sulfonylureas, which stimulate the release of insulin. Instead, it blocks enzymes in the small intestine that break down complex sugars into glucose. This slows down the absorption of glucose by the body and helps to reduce post-meal blood sugar levels in diabetic patients.
When to interrupt dosage
The endorsed dose of Miglitol is subject to the identified condition, including Type 2 Diabetes, Physical Activity and Diet. The amount of dosage fluctuates, as outlined by the course of delivery (e.g. Tablet, coated - Oral or Oral) detailed in the table below.Condition
Dosage
Administration
Type 2 Diabetes
, 50.0 mg, 100.0 mg, 25.0 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated - Oral, Tablet, film coated
Physical Activity
, 50.0 mg, 100.0 mg, 25.0 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated - Oral, Tablet, film coated
Diet
, 50.0 mg, 100.0 mg, 25.0 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated - Oral, Tablet, film coated
Warnings
Miglitol has nine contraindications, and its use should be abstained from when dealing with any of the conditions stated in the subsequent table.Miglitol ContraindicationsCondition
Risk Level
Notes
Digestive Disorders
Do Not Combine
Pulse Frequency
Do Not Combine
Disease
Do Not Combine
partial intestinal obstruction
Do Not Combine
colonic ulceration
Do Not Combine
Crohn's Disease
Do Not Combine
Intestines
Do Not Combine
Diabetic Ketoacidosis
Do Not Combine
Capillaria philippinensis Infection
Do Not Combine
Common Miglitol Drug Interactions
Drug Name
Risk Level
Description
Ketotifen
Minor
The risk or severity of thrombocytopenia can be increased when Miglitol is combined with Ketotifen.
2,4-thiazolidinedione
Moderate
The risk or severity of hypoglycemia can be increased when Miglitol is combined with 2,4-thiazolidinedione.
AICA ribonucleotide
Moderate
The risk or severity of hypoglycemia can be increased when Miglitol is combined with AICA ribonucleotide.
AMG-222
Moderate
The risk or severity of hypoglycemia can be increased when Miglitol is combined with AMG-222.
Acetohexamide
Moderate
The risk or severity of hypoglycemia can be increased when Miglitol is combined with Acetohexamide.
Miglitol Toxicity & Overdose RiskIf you're taking miglitol, don't worry about an overdose causing low blood sugar levels. An overdose may cause an increase in gas, diarrhea, and stomach upset. However, no serious systemic reactions are expected after taking too much miglitol.
Miglitol Novel Uses: Which Conditions Have a Clinical Trial Featuring Miglitol?
196 active trials are currently assessing the potential of Miglitol to improve Diet, Type 2 Diabetes and Physical Activity outcomes.Condition
Clinical Trials
Trial Phases
Diet
5 Actively Recruiting
Not Applicable
Physical Activity
39 Actively Recruiting
Not Applicable, Phase 2, Phase 1, Early Phase 1
Type 2 Diabetes
192 Actively Recruiting
Phase 2, Not Applicable, Early Phase 1, Phase 1, Phase 4, Phase 3
Miglitol Reviews: What are patients saying about Miglitol?
2Patient Review
12/9/2012 I was initially pleased with the results of this medication, but now I find that it gives me erectile dysfunction. This is a frustrating side effect that seems to be common among many drugs.
Patient Q&A Section about miglitol
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is miglitol used for?
"Miglitol is used to lower high blood sugar levels that are caused by type 2 diabetes."
Answered by AI
When should miglitol be taken?
"Miglitol comes in the form of a tablet that is meant to be taken orally. The recommended dosage is three times a day, with the first dose being taken during the first bite of a meal. It is important to follow the directions on the prescription label carefully and to ask for clarification from a doctor or pharmacist if anything is unclear."
Answered by AI
What are the side effects of miglitol?
"Diarrhea, gas, upset stomach, stomach or abdominal pain, skin rash, or iron deficiency anemia are common side effects in the first few weeks of treatment as the body adjusts to this medication but these side effects usually improve with time."
Answered by AI
What type of medication is miglitol?
"Miglitol works by delaying the digestion of carbohydrates. It inhibits the breakdown of complex carbohydrates into glucose, which helps improve glycemic control."
Answered by AI