Megestrol Acetate

Endometrial Neoplasms, Endometrial Neoplasms, Acquired Immunodeficiency Syndrome + 7 more
Treatment
5 Active Studies for Megestrol Acetate

What is Megestrol Acetate

Megestrol acetateThe Generic name of this drug
Treatment SummaryNomegestrol acetate (NOMAC) is a hormone medication used in birth control pills, hormone replacement therapy for menopause, and for the treatment of certain gynecological conditions.
Megestrol Acetateis the brand name
image of different drug pills on a surface
Megestrol Acetate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Megestrol Acetate
Megestrol acetate
1988
76

When to interrupt dosage

The portion of Megestrol Acetate corresponds to the recognized ailment, including Oral Contraceptives, Luteal deficiency and Hormone Replacement Therapy. The amount of dosage is contingent upon the technique of delivery (e.g. Tablet, film coated or Tablet, film coated - Oral) featured in the table beneath.
Condition
Dosage
Administration
Endometrial Neoplasms
, 40.0 mg, 125.0 mg/mL, 40.0 mg/mL, 20.0 mg, 80.0 mg/mL, 160.0 mg, 625.0 mg/mL
, Tablet, Oral, Tablet - Oral, Suspension, Suspension - Oral
Endometrial Neoplasms
, 40.0 mg, 125.0 mg/mL, 40.0 mg/mL, 20.0 mg, 80.0 mg/mL, 160.0 mg, 625.0 mg/mL
, Tablet, Oral, Tablet - Oral, Suspension, Suspension - Oral
Acquired Immunodeficiency Syndrome
, 40.0 mg, 125.0 mg/mL, 40.0 mg/mL, 20.0 mg, 80.0 mg/mL, 160.0 mg, 625.0 mg/mL
, Tablet, Oral, Tablet - Oral, Suspension, Suspension - Oral
Palliative Treatment
, 40.0 mg, 125.0 mg/mL, 40.0 mg/mL, 20.0 mg, 80.0 mg/mL, 160.0 mg, 625.0 mg/mL
, Tablet, Oral, Tablet - Oral, Suspension, Suspension - Oral
Anorexia
, 40.0 mg, 125.0 mg/mL, 40.0 mg/mL, 20.0 mg, 80.0 mg/mL, 160.0 mg, 625.0 mg/mL
, Tablet, Oral, Tablet - Oral, Suspension, Suspension - Oral
Breast
, 40.0 mg, 125.0 mg/mL, 40.0 mg/mL, 20.0 mg, 80.0 mg/mL, 160.0 mg, 625.0 mg/mL
, Tablet, Oral, Tablet - Oral, Suspension, Suspension - Oral
Endometrial Carcinoma
, 40.0 mg, 125.0 mg/mL, 40.0 mg/mL, 20.0 mg, 80.0 mg/mL, 160.0 mg, 625.0 mg/mL
, Tablet, Oral, Tablet - Oral, Suspension, Suspension - Oral
Weight decreased
, 40.0 mg, 125.0 mg/mL, 40.0 mg/mL, 20.0 mg, 80.0 mg/mL, 160.0 mg, 625.0 mg/mL
, Tablet, Oral, Tablet - Oral, Suspension, Suspension - Oral
Breast
, 40.0 mg, 125.0 mg/mL, 40.0 mg/mL, 20.0 mg, 80.0 mg/mL, 160.0 mg, 625.0 mg/mL
, Tablet, Oral, Tablet - Oral, Suspension, Suspension - Oral
Breast
, 40.0 mg, 125.0 mg/mL, 40.0 mg/mL, 20.0 mg, 80.0 mg/mL, 160.0 mg, 625.0 mg/mL
, Tablet, Oral, Tablet - Oral, Suspension, Suspension - Oral

Warnings

Megestrol Acetate Contraindications
Condition
Risk Level
Notes
suspected pregnancy
Do Not Combine
There are 20 known major drug interactions with Megestrol Acetate.
Common Megestrol Acetate Drug Interactions
Drug Name
Risk Level
Description
Dofetilide
Major
Megestrol acetate may decrease the excretion rate of Dofetilide which could result in a higher serum level.
Tranexamic acid
Major
Megestrol acetate may increase the thrombogenic activities of Tranexamic acid.
Abacavir
Minor
Megestrol acetate may decrease the excretion rate of Abacavir which could result in a higher serum level.
Acetohexamide
Minor
The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Megestrol acetate.
Aclidinium
Minor
Megestrol acetate may decrease the excretion rate of Aclidinium which could result in a higher serum level.
image of a doctor in a lab doing drug, clinical research

Megestrol Acetate Novel Uses: Which Conditions Have a Clinical Trial Featuring Megestrol Acetate?

Two active studies are currently evaluating the potential of Megestrol Acetate to provide Hormone Replacement Therapy, ameliorate Luteal Insufficiency and reduce Menopausal Symptoms.
Condition
Clinical Trials
Trial Phases
Endometrial Neoplasms
0 Actively Recruiting
Endometrial Carcinoma
0 Actively Recruiting
Palliative Treatment
1 Actively Recruiting
Phase 3
Anorexia
1 Actively Recruiting
Phase 1
Breast
0 Actively Recruiting
Breast
0 Actively Recruiting
Breast
0 Actively Recruiting
Weight decreased
0 Actively Recruiting
Acquired Immunodeficiency Syndrome
3 Actively Recruiting
Phase 1, Phase 2, Not Applicable
Endometrial Neoplasms
0 Actively Recruiting

Megestrol Acetate Reviews: What are patients saying about Megestrol Acetate?

5Patient Review
10/9/2013
Megestrol Acetate for "Change of Life" Signs
I menopause has been a really tough time for me, but this medication has helped to ease some of the symptoms.
5Patient Review
8/13/2011
Megestrol Acetate for "Change of Life" Signs
I was bleeding and spotting for three months before I started this medication, but after just three days on it, the bleeding stopped. I was originally prescribed it for four months, but I was worried about the side effect of weight gain. However, two months in and I haven't gained any weight.
5Patient Review
8/25/2013
Megestrol Acetate for Metastatic Endometrial Carcinoma
I'm doing well on this medication, though I am struggling to keep my weight down. I've gained about eight pounds since starting the treatment.
4.7Patient Review
2/18/2012
Megestrol Acetate for Cancer in the Lining of the Uterus
I've been taking this medication for over two years to treat endometrial hyperplasia. Thankfully, my condition has improved and I was able to lower the dosage. When I started taking the meds, I did gain weight; however, I have since lost some of it.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about megestrol acetate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

When should megestrol be taken?

"You should take megestrol acetate once a day, at the same time each day. However, sometimes the dose is divided up and you will need to take the tablets a couple of times a day."

Answered by AI

Do megestrol acetate make u gain weight?

"What does this medicine do? MEGESTROL (me JES trol) suspension is used to improve appetite and help cause weight gain in conditions that cause significant loss of appetite and weight, such as AIDS."

Answered by AI

What are the side effects of megestrol acetate?

"If you experience any of the following side effects, tell your doctor or pharmacist immediately as they may get worse: trouble sleeping, fever, gas, decreased sexual ability/desire, weight gain, changes in appetite, upset stomach, changes in menstrual periods (including unpredictable bleeding)."

Answered by AI

What is megestrol acetate used for?

"It treats breast cancer and endometrial cancer by affecting female hormones involved in cancer growth, and it increases weight gain by increasing appetite."

Answered by AI

Clinical Trials for Megestrol Acetate

Have you considered Megestrol Acetate clinical trials? We made a collection of clinical trials featuring Megestrol Acetate, we think they might fit your search criteria.
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