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What is Lysteda
Tranexamic acidThe Generic name of this drug
Treatment SummaryTranexamic acid is a medication derived from lysine that is used to prevent or reduce excessive bleeding. It works by preventing the breakdown of blood clots and is more powerful than other similar drugs. Tranexamic acid was first patented in 1957 and received FDA approval in 1986.
Cyklokapronis the brand name
Lysteda Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Cyklokapron
Tranexamic acid
1986
57
Effectiveness
How Lysteda Affects PatientsTranexamic acid is a medication that stops the breakdown of blood clots. It works by blocking the enzyme plasmin, which helps break down clots. This medication is 10 times more effective than a similar drug called aminocaproic acid. Tranexamic acid is used to prevent attacks of angioedema, a condition where swelling occurs in the face or throat, by reducing the activity of plasmin. While this drug can reduce the risk of seizures, there is a risk of convulsions and increased excitability if it's not properly administered or used during cardiovascular surgery. It is recommended to
How Lysteda works in the bodyTranexamic acid helps to prevent bleeding by preventing plasminogen from binding to fibrin. Plasminogen is a molecule that helps to dissolve clots, so tranexamic acid prevents it from doing its job. This allows the clot to remain stable and prevents hemorrhage.
When to interrupt dosage
The measure of Lysteda is contingent upon the perceived affliction, including Tooth Extractions, Angioedemas, Hereditary and Hemophilia. The dosage fluctuates according to the method of administration (e.g. Cream - Topical or Injection, solution - Intravenous) detailed in the table beneath.Condition
Dosage
Administration
Angioedemas, Hereditary
100.0 mg/mL, , 650.0 mg, 0.005 mg/mL, 500.0 mg, 2.0 mg/mL, 5.0 mg/mL, 0.1 mg/mL, 10.0 mg/mL, 500.0 mg/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, Tablet - Oral, Oral, Tablet, film coated, Tablet, film coated - Oral, Topical, Cream, Cream - Topical, Solution, Solution - Intravenous, Injection, Injection - Intravenous, Liquid, Liquid - Topical
Hyperfibrinolysis
100.0 mg/mL, , 650.0 mg, 0.005 mg/mL, 500.0 mg, 2.0 mg/mL, 5.0 mg/mL, 0.1 mg/mL, 10.0 mg/mL, 500.0 mg/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, Tablet - Oral, Oral, Tablet, film coated, Tablet, film coated - Oral, Topical, Cream, Cream - Topical, Solution, Solution - Intravenous, Injection, Injection - Intravenous, Liquid, Liquid - Topical
Hemorrhage
100.0 mg/mL, , 650.0 mg, 0.005 mg/mL, 500.0 mg, 2.0 mg/mL, 5.0 mg/mL, 0.1 mg/mL, 10.0 mg/mL, 500.0 mg/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, Tablet - Oral, Oral, Tablet, film coated, Tablet, film coated - Oral, Topical, Cream, Cream - Topical, Solution, Solution - Intravenous, Injection, Injection - Intravenous, Liquid, Liquid - Topical
Hemophilia
100.0 mg/mL, , 650.0 mg, 0.005 mg/mL, 500.0 mg, 2.0 mg/mL, 5.0 mg/mL, 0.1 mg/mL, 10.0 mg/mL, 500.0 mg/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, Tablet - Oral, Oral, Tablet, film coated, Tablet, film coated - Oral, Topical, Cream, Cream - Topical, Solution, Solution - Intravenous, Injection, Injection - Intravenous, Liquid, Liquid - Topical
Menorrhagia
100.0 mg/mL, , 650.0 mg, 0.005 mg/mL, 500.0 mg, 2.0 mg/mL, 5.0 mg/mL, 0.1 mg/mL, 10.0 mg/mL, 500.0 mg/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, Tablet - Oral, Oral, Tablet, film coated, Tablet, film coated - Oral, Topical, Cream, Cream - Topical, Solution, Solution - Intravenous, Injection, Injection - Intravenous, Liquid, Liquid - Topical
Tooth Extractions
100.0 mg/mL, , 650.0 mg, 0.005 mg/mL, 500.0 mg, 2.0 mg/mL, 5.0 mg/mL, 0.1 mg/mL, 10.0 mg/mL, 500.0 mg/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, Tablet - Oral, Oral, Tablet, film coated, Tablet, film coated - Oral, Topical, Cream, Cream - Topical, Solution, Solution - Intravenous, Injection, Injection - Intravenous, Liquid, Liquid - Topical
Warnings
Lysteda has six contraindications. It should not be taken if you have any of the circumstances detailed in the subsequent table.Lysteda ContraindicationsCondition
Risk Level
Notes
NF1 gene
Do Not Combine
active intravascular clotting
Do Not Combine
history of thromboembolism
Do Not Combine
Pulse Frequency
Do Not Combine
Subarachnoid Hemorrhage
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Tranexamic Acid may interact with Pulse Frequency
Common Lysteda Drug Interactions
Drug Name
Risk Level
Description
Albutrepenonacog alfa
Major
Tranexamic acid may increase the thrombogenic activities of Albutrepenonacog alfa.
Aminocaproic acid
Major
Tranexamic acid may increase the thrombogenic activities of Aminocaproic acid.
Aminomethylbenzoic acid
Major
Tranexamic acid may increase the thrombogenic activities of Aminomethylbenzoic acid.
Andexanet alfa
Major
Tranexamic acid may increase the thrombogenic activities of Andexanet alfa.
Anti-inhibitor coagulant complex
Major
Tranexamic acid may increase the thrombogenic activities of Anti-inhibitor coagulant complex.
Lysteda Toxicity & Overdose RiskTaking too much tranexamic acid may result in stomachaches, low blood pressure, blood clots, vision issues, seizures, changes in behavior, and skin rashes.
Lysteda Novel Uses: Which Conditions Have a Clinical Trial Featuring Lysteda?
34 active studies are presently investigating the potential of Lysteda to manage Hemophilia, Hereditary Hemorrhage and Angioedemas.Condition
Clinical Trials
Trial Phases
Tooth Extractions
3 Actively Recruiting
Not Applicable
Hyperfibrinolysis
0 Actively Recruiting
Hemorrhage
13 Actively Recruiting
Phase 4, Phase 3, Not Applicable, Phase 1, Phase 2
Menorrhagia
3 Actively Recruiting
Phase 3, Phase 4, Not Applicable
Hemophilia
4 Actively Recruiting
Phase 3
Angioedemas, Hereditary
13 Actively Recruiting
Phase 2, Phase 3, Phase 1
Lysteda Reviews: What are patients saying about Lysteda?
5Patient Review
5/28/2014 I had extremely heavy periods due to a 7cm fibroid. My doctor prescribed this medication, and it has been an absolute life-saver. I highly recommend it to anyone who is dealing with heavy periods.
5Patient Review
7/30/2014 I called it the miracle drug because it worked so well for me with no side effects.
5Patient Review
9/2/2017 Lysteda was a life-saver for me. I had to take it days before my fibroid surgery due to heavy bleeding, and it worked immediately. I would highly recommend this medication to anyone dealing with similar issues.
5Patient Review
11/20/2015 This pill has been a life-saver, especially given that I'm already 52. Heavier and longer periods were becoming unmanageable, but this medication put a stop to it.
4.3Patient Review
9/24/2017 As an elementary teacher, it can be really tough to deal with my period. I was experiencing heavy bleeding and needed to go to the bathroom frequently, which made things even more difficult.
4.3Patient Review
9/12/2017 Not a miracle cure, but this treatment has definitely improved my quality of life. The pain is manageable now instead of debilitating. Give it time to work; I didn't see results for a few months, but they were well worth the wait.
4.3Patient Review
3/7/2016 Lysteda has helped me to manage my heavy bleeding and fibroids by cutting down the amount of blood flow and clots. The occasional headaches are a manageable side effect. I take two pills, three times a day for five days when needed.
4Patient Review
11/20/2019 I'm 51 years old with multiple fibroids, and I'm not ready for a hysterectomy. So, I decided to give Lysteda a try. Three days in, and I'm already thrilled that I don't have to change my pad every hour. The pain is tolerable, and I can wear a tampon without any issues. Here's hoping this keeps working well!
4Patient Review
6/30/2022 Lysteda helped to reduce my heavy periods caused by fibroids, but I still experience some flooding on the first day of my period. After the first two days, the bleeding is much lighter and I don't need to take as high of a dose. The main side effect I've experienced is mild headaches and fatigue.
4Patient Review
2/23/2018 I found this drug to be helpful while going through menopause.
1.7Patient Review
7/14/2016 Lysteda was unfortunately ineffective for me. I still experience heavy, long periods despite taking this medication as prescribed.
Patient Q&A Section about lysteda
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What are the side effects of Lysteda?
"fatigue
The main symptoms of the coronavirus are nausea, vomiting, diarrhea, joint or muscle pain, muscle cramps, headache or migraine, runny or stuffy nose, stomach or abdominal pain, and fatigue."
Answered by AI
Does Lysteda shorten your period?
"The results showed that LYSTEDA can reduce menstrual flow by nearly 40%. A wide range of patients benefited from the treatment in the clinical studies, including women ages 18 to 49 with body mass indexes from 25 to more than 30, and individuals with and without uterine fibroids."
Answered by AI
How long does Lysteda stop bleeding?
"There are no hormones in LYSTEDA and it will not impact your fertility. You only take it during your period for up to 5 days, not every day. On average, LYSTEDA has been shown to reduce blood loss by one-third for women with HMB**."
Answered by AI
How does Lysteda stop bleeding?
"The purpose of this medication is to treat heavy bleeding during menstruation. Tranexamic acid slows the breakdown of blood clots, which helps to prevent prolonged bleeding. It belongs to a class of drugs called antifibrinolytics."
Answered by AI