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What is Lotrimin
ButenafineThe Generic name of this drug
Treatment SummaryMiconazole is an antifungal medication used to treat yeast infections of the mouth and vagina. It is available in a variety of forms such as creams, gels, suppositories, and tablets, and can be prescribed or purchased over the counter. Miconazole was approved by the FDA in 1974 and has been in clinical use for many years. The drug works by inhibiting a fungal enzyme and has been found to be relatively resistant to resistance from fungi.
Lotrimin Ultra Antifungalis the brand name
Lotrimin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Lotrimin Ultra Antifungal
Butenafine
1993
22
Effectiveness
How Lotrimin Affects PatientsMiconazole is an antifungal medication that is usually applied directly to the skin. It works by blocking a certain enzyme that helps fungi grow. The drug is usually not absorbed into the body, so reactions tend to be limited to allergies and anaphylaxis. Women using miconazole products should not use tampons at the same time and should not rely on contraceptives to prevent pregnancy or sexually transmitted infections.
How Lotrimin works in the bodyMiconazole is an antifungal medication used to treat infections caused by the Candida fungus. It works in three ways. First, it stops fungi from producing the right kind of fats for cell membranes, making the cells more porous and leading to the leakage of proteins and other molecules. Second, it boosts the production of reactive oxygen species (ROS) within the cell, leading to cell death. Lastly, it increases farnesol levels, which prevent the fungus from changing shape and forming a biofilm, which are harder to treat with antibiotics. It also inhibits drug efflux proteins, which makes miconazole more
When to interrupt dosage
The recommended dose of Lotrimin hinges upon the recognized situation, such as Gastrointestinal candidiasis, Nail candida and Infection, Mixed. The measure of dosage is contingent upon administration technique (e.g. Topical or Aerosol, spray - Topical) listed in the table below.Condition
Dosage
Administration
Tinea Pedis
, 0.01 mg/mg, 1.0 %
, Topical, Cream, Cream - Topical
Pityriasis versicolor
, 0.01 mg/mg, 1.0 %
, Topical, Cream, Cream - Topical
Tinea cruris
, 0.01 mg/mg, 1.0 %
, Topical, Cream, Cream - Topical
Tinea Corporis
, 0.01 mg/mg, 1.0 %
, Topical, Cream, Cream - Topical
Warnings
Lotrimin has two contraindications and must not be taken if the individual is experiencing any of the conditions in the following table.Common Lotrimin Drug Interactions
Drug Name
Risk Level
Description
Lotrimin Toxicity & Overdose RiskTaking too much miconazole can lead to symptoms such as headaches, skin irritation, diarrhea, nausea, vomiting, stomach pain, and a distorted sense of taste. It is recommended to seek medical help and provide supportive care for those who overdose. A lethal dose for rats is 500mg/kg.
Lotrimin Novel Uses: Which Conditions Have a Clinical Trial Featuring Lotrimin?
203 active trials are currently being conducted to evaluate the potential of Lotrimin in ameliorating Dermatophytosis, Inflammation and Profuse Perspiration with accompanying body odor.Condition
Clinical Trials
Trial Phases
Tinea Corporis
0 Actively Recruiting
Tinea Pedis
0 Actively Recruiting
Pityriasis versicolor
0 Actively Recruiting
Tinea cruris
0 Actively Recruiting
Lotrimin Reviews: What are patients saying about Lotrimin?
4.7Patient Review
8/9/2014 I had a self-diagnosed yeast infection of the skin in my perineal area. I mixed equal parts Lotrimin with zinc oxide and applied it 3 times a day for about a week. It cleared up quickly and effectively.
3Patient Review
11/7/2017 I liked the treatment, but I accidentally sprayed too much and now my skin is pale and there's a dark spot where it was applied. It's also burning and numb. I don't know what to do or what this is.
1Patient Review
9/1/2016 I had ringworm on my face and applied Lotrimin as directed. In less than 24 hours I got severe allergic reaction, which only developed around the area where I applied the cream (my cheeks). The next day I woke up with my eyes shot, severe redness, swelling and itchiness. I was unable to sleep and had to go to the emergency room.
Patient Q&A Section about lotrimin
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Lotrimin ointment used for?
"This medication can be used to treat fungal infections of the skin such as ringworm, athlete's foot, and jock itch. It can also be used to treat pityriasis, a fungal infection that causes changes in skin color."
Answered by AI
Why has Lotrimin been recalled?
"Bayer is recalling all unexpired Lotrimin AF and Tinactin spray products with lot numbers beginning with TN, CV or NAA, distributed between September 2018 to September 2021, due to the presence of benzene in some samples of the products."
Answered by AI
Is Lotrimin good for yeast infection?
"This medication is used to treat vaginal yeast infections. It reduces the burning, itching, and discharge that may come with the infection. The medication is an azole antifungal. It works by stopping the growth of yeast (fungus) that causes the infection."
Answered by AI
Is Lotrimin and clotrimazole the same thing?
"Clotrimazole, which is sold under the brand name Lotrimin, is an antifungal medication that can be used to treat vaginal yeast infections, oral thrush, diaper rash, tinea versicolor, and types of ringworm, including athlete's foot and jock itch."
Answered by AI